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The map label for this gene is tqsA [H]

Identifier: 29141854

GI number: 29141854

Start: 1446522

End: 1447556

Strand: Reverse

Name: tqsA [H]

Synonym: t1401

Alternate gene names: 29141854

Gene position: 1447556-1446522 (Counterclockwise)

Preceding gene: 29141857

Following gene: 29141851

Centisome position: 30.21

GC content: 49.37

Gene sequence:

>1035_bases
ATGGCAAAACCGATCATCACGCTCAATGGTCTAAAAATCGTCATTATGCTGGGAATGCTGGTGGTTATTCTGAGCGGTAT
CCGCTTCGCCGCAGATATCATTGTTCCCTTTATTTTGGCGTTATTTATTGCAGTCGTTCTCAATCCCGTTGTGCAACGGA
TGACCCGATGTCGAATTCCGCGCGTTATCGCCGTATCATTGCTCATTGTGATTATTGTTATGTTAATGGTACTGCTACTG
GCCTATTTGGGGACATCATTAAATGAACTGGCCCGTACCCTACCGCAGTATCGCTCCTCATTGGTGATACCGTTGCAACG
TATTGAACCGTGGTTGCAGCGAGCAGGCATTGGCGTGTCGGTTGATGAGCTGGCGAAATATATCGATCCAAACGCCGCCA
TGACTCTGGTAACGAACCTGCTCACCCAACTGTCCAATGCCATGTCATCCATCTTTTTATTGTTATTGACCGTGGTATTC
ATGCTGCTGGAGGTTCCACAACTGCCTGAAAAACTGCAGCAGATGATGAGCCGTCCGGTAGAAGGTATGGCGGCAATTCA
ACGCGCGCTTGATAGCGTTTCACATTATCTGGTGCTAAAAACAGCGATCAGTATCGTGACGGGACTGGTCGCATGGGGAA
TGCTGGCCGCTCTGGATGTCCGCTTCGCCTTTGTCTGGGGTCTACTGGCCTTCGCGCTGAACTATATCCCTAATATTGGA
TCGGTGCTCGCTGCCCTGCCGCCCATTATTCAGGTGCTGGTATTTAACGGGTTTTATGATGCGCTGCTGGTGCTGGCGGG
CTATCTGCTGATTAATCTGGTCTTCGGCAATATCCTTGAGCCACGTATCATGGGACGTGGTTTAGGCCTTTCAACCTTAG
TGGTATTTTTGTCGTTAATTTTCTGGGGCTGGCTATTAGGTCCGGTGGGCATGTTGCTCTCCGTTCCGTTAACCATCATT
GTCAAAATCGCCCTCGAACAGACCACCGGCGGGCAGAGTATCGCCGTTCTGCTTAGCGATTTAAACAAAAGATAA

Upstream 100 bases:

>100_bases
AAATATTTTCACTTCTTTACCTGAAGTGTTTGATTTTAACCAGAACAGGTCGACCGACATCACATTATTATTCGTGTCGG
CATAGAAAACAGGGACTGAT

Downstream 100 bases:

>100_bases
AATGCAATATATACACAAAATCATTCAAGATGCATCGCGGCGGCAAGGGAAGAAATCCCCGGGAGCATAGATAACGATGT
GACCGGGGTTTCTGAGCGCA

Product: transport protein

Products: NA

Alternate protein names: Transport of quorum-sensing signal protein [H]

Number of amino acids: Translated: 344; Mature: 343

Protein sequence:

>344_residues
MAKPIITLNGLKIVIMLGMLVVILSGIRFAADIIVPFILALFIAVVLNPVVQRMTRCRIPRVIAVSLLIVIIVMLMVLLL
AYLGTSLNELARTLPQYRSSLVIPLQRIEPWLQRAGIGVSVDELAKYIDPNAAMTLVTNLLTQLSNAMSSIFLLLLTVVF
MLLEVPQLPEKLQQMMSRPVEGMAAIQRALDSVSHYLVLKTAISIVTGLVAWGMLAALDVRFAFVWGLLAFALNYIPNIG
SVLAALPPIIQVLVFNGFYDALLVLAGYLLINLVFGNILEPRIMGRGLGLSTLVVFLSLIFWGWLLGPVGMLLSVPLTII
VKIALEQTTGGQSIAVLLSDLNKR

Sequences:

>Translated_344_residues
MAKPIITLNGLKIVIMLGMLVVILSGIRFAADIIVPFILALFIAVVLNPVVQRMTRCRIPRVIAVSLLIVIIVMLMVLLL
AYLGTSLNELARTLPQYRSSLVIPLQRIEPWLQRAGIGVSVDELAKYIDPNAAMTLVTNLLTQLSNAMSSIFLLLLTVVF
MLLEVPQLPEKLQQMMSRPVEGMAAIQRALDSVSHYLVLKTAISIVTGLVAWGMLAALDVRFAFVWGLLAFALNYIPNIG
SVLAALPPIIQVLVFNGFYDALLVLAGYLLINLVFGNILEPRIMGRGLGLSTLVVFLSLIFWGWLLGPVGMLLSVPLTII
VKIALEQTTGGQSIAVLLSDLNKR
>Mature_343_residues
AKPIITLNGLKIVIMLGMLVVILSGIRFAADIIVPFILALFIAVVLNPVVQRMTRCRIPRVIAVSLLIVIIVMLMVLLLA
YLGTSLNELARTLPQYRSSLVIPLQRIEPWLQRAGIGVSVDELAKYIDPNAAMTLVTNLLTQLSNAMSSIFLLLLTVVFM
LLEVPQLPEKLQQMMSRPVEGMAAIQRALDSVSHYLVLKTAISIVTGLVAWGMLAALDVRFAFVWGLLAFALNYIPNIGS
VLAALPPIIQVLVFNGFYDALLVLAGYLLINLVFGNILEPRIMGRGLGLSTLVVFLSLIFWGWLLGPVGMLLSVPLTIIV
KIALEQTTGGQSIAVLLSDLNKR

Specific function: Controls the transport of the quorum-sensing signal AI-2 either by enhancing its secretion or inhibiting its uptake and consequently represses biofilm formation and motility and affects the global gene expression in biofilms [H]

COG id: COG0628

COG function: function code R; Predicted permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0118 (perM) family [H]

Homologues:

Organism=Escherichia coli, GI1787885, Length=344, Percent_Identity=88.0813953488372, Blast_Score=555, Evalue=1e-159,
Organism=Escherichia coli, GI87082271, Length=339, Percent_Identity=46.9026548672566, Blast_Score=300, Evalue=7e-83,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002549 [H]

Pfam domain/function: PF01594 UPF0118 [H]

EC number: NA

Molecular weight: Translated: 37546; Mature: 37414

Theoretical pI: Translated: 10.15; Mature: 10.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKPIITLNGLKIVIMLGMLVVILSGIRFAADIIVPFILALFIAVVLNPVVQRMTRCRIP
CCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
RVIAVSLLIVIIVMLMVLLLAYLGTSLNELARTLPQYRSSLVIPLQRIEPWLQRAGIGVS
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
VDELAKYIDPNAAMTLVTNLLTQLSNAMSSIFLLLLTVVFMLLEVPQLPEKLQQMMSRPV
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCH
EGMAAIQRALDSVSHYLVLKTAISIVTGLVAWGMLAALDVRFAFVWGLLAFALNYIPNIG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
SVLAALPPIIQVLVFNGFYDALLVLAGYLLINLVFGNILEPRIMGRGLGLSTLVVFLSLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
FWGWLLGPVGMLLSVPLTIIVKIALEQTTGGQSIAVLLSDLNKR
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCC
>Mature Secondary Structure 
AKPIITLNGLKIVIMLGMLVVILSGIRFAADIIVPFILALFIAVVLNPVVQRMTRCRIP
CCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
RVIAVSLLIVIIVMLMVLLLAYLGTSLNELARTLPQYRSSLVIPLQRIEPWLQRAGIGVS
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
VDELAKYIDPNAAMTLVTNLLTQLSNAMSSIFLLLLTVVFMLLEVPQLPEKLQQMMSRPV
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCH
EGMAAIQRALDSVSHYLVLKTAISIVTGLVAWGMLAALDVRFAFVWGLLAFALNYIPNIG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
SVLAALPPIIQVLVFNGFYDALLVLAGYLLINLVFGNILEPRIMGRGLGLSTLVVFLSLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
FWGWLLGPVGMLLSVPLTIIVKIALEQTTGGQSIAVLLSDLNKR
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]