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The map label for this gene is lrhA [H]

Identifier: 29141049

GI number: 29141049

Start: 608626

End: 609564

Strand: Direct

Name: lrhA [H]

Synonym: t0534

Alternate gene names: 29141049

Gene position: 608626-609564 (Clockwise)

Preceding gene: 29141046

Following gene: 29141050

Centisome position: 12.7

GC content: 52.18

Gene sequence:

>939_bases
ATGATAAATGCAAATCGTCCGATAATTAACCTCGATCTCGATCTGCTGAGAACGTTCGTGGCCGTTGCCGATCTGAACAC
CTTCGCCGCGGCGGCGGCGGCGGTATGTCGTACTCAGTCTGCGGTCAGTCAGCAAATGCAGCGTCTTGAGCAACTCGTGG
GAAAGGAATTGTTCGCCCGCCATGGTCGTAACAAACTTTTGAGCGAACACGGTATCCAGCTTCTGGGGTACGCCAGAAAA
ATCCTGCGTTTTAATGATGAGGCGTGTTCATCATTAATGTTCAGTAATCTTCAGGGAGTGTTAACAATCGGCGCTTCTGA
TGAATCAGCTGATACTATCCTGCCTTTTTTGCTTAGCCGAATCAGCTCGGTTTATCCGAAACTCGCGCTTGATGTACGGG
TAAAACGCAACGCCTATATGGTGGACATGGTTAAATCGCAGGAAGTAGATTTGGTGGTGACGACTAACCAACCTCATTCG
CTGGACTGTCTGAATTTGCGGACCTCGCCCACCCATTGGTATTGTGCGGCTGAGTATGTTTTGCAAAGGGGAGAGCCCGT
ACCATTAGTCCTGCTGGACGATCCCAGCCCATTCCGCGATATGGTGCTGGAGACGCTAAATGCAGCGGGTATTCCCTGGC
GGCTGGCCTATGTGGCCTCTACATTACTGGCGGTACGCGCGGCCGTTAAAGCCGGTCTTGGCGTAACGGCTCGACCTGTC
GAAATGATGAGTCCCGACCTTCGCGTGCTGGGCGCCGCAGATGGATTACCGCCTTTGCTGGATACGGAATATATGTTGTG
CCGCGATCCCAATAGCCAGAACGAGCTGGCGATGGTGATTTTCCATGCGATGGAAAGCTATCAAAACCCATGGCATTACA
ACCAGTTTTCTGCAGAGGGCGGAGATGATCCGCTGATGGTGGAAGGGGGTTTTGAGTAG

Upstream 100 bases:

>100_bases
GGTACTGCGAAGGATGCACATTACAAATGGAATTGCTTGTTTCTGAATGCACAGCATTAACCAGGTCAGCCCGATATGAC
CCGTCAGTAAGTGAAAAATT

Downstream 100 bases:

>100_bases
CTCGCAGGCAAAAGGCGCTAAGTCGTAAATGTAAAAAAGAGCCGCTGGCGATGAAAAAACGCTCAGTGGCTCTTTTTTTG
TGCCCATCTGTACGCGCTTA

Product: NADH dehydrogenase operon transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 312; Mature: 312

Protein sequence:

>312_residues
MINANRPIINLDLDLLRTFVAVADLNTFAAAAAAVCRTQSAVSQQMQRLEQLVGKELFARHGRNKLLSEHGIQLLGYARK
ILRFNDEACSSLMFSNLQGVLTIGASDESADTILPFLLSRISSVYPKLALDVRVKRNAYMVDMVKSQEVDLVVTTNQPHS
LDCLNLRTSPTHWYCAAEYVLQRGEPVPLVLLDDPSPFRDMVLETLNAAGIPWRLAYVASTLLAVRAAVKAGLGVTARPV
EMMSPDLRVLGAADGLPPLLDTEYMLCRDPNSQNELAMVIFHAMESYQNPWHYNQFSAEGGDDPLMVEGGFE

Sequences:

>Translated_312_residues
MINANRPIINLDLDLLRTFVAVADLNTFAAAAAAVCRTQSAVSQQMQRLEQLVGKELFARHGRNKLLSEHGIQLLGYARK
ILRFNDEACSSLMFSNLQGVLTIGASDESADTILPFLLSRISSVYPKLALDVRVKRNAYMVDMVKSQEVDLVVTTNQPHS
LDCLNLRTSPTHWYCAAEYVLQRGEPVPLVLLDDPSPFRDMVLETLNAAGIPWRLAYVASTLLAVRAAVKAGLGVTARPV
EMMSPDLRVLGAADGLPPLLDTEYMLCRDPNSQNELAMVIFHAMESYQNPWHYNQFSAEGGDDPLMVEGGFE
>Mature_312_residues
MINANRPIINLDLDLLRTFVAVADLNTFAAAAAAVCRTQSAVSQQMQRLEQLVGKELFARHGRNKLLSEHGIQLLGYARK
ILRFNDEACSSLMFSNLQGVLTIGASDESADTILPFLLSRISSVYPKLALDVRVKRNAYMVDMVKSQEVDLVVTTNQPHS
LDCLNLRTSPTHWYCAAEYVLQRGEPVPLVLLDDPSPFRDMVLETLNAAGIPWRLAYVASTLLAVRAAVKAGLGVTARPV
EMMSPDLRVLGAADGLPPLLDTEYMLCRDPNSQNELAMVIFHAMESYQNPWHYNQFSAEGGDDPLMVEGGFE

Specific function: Not known, does not seem to act on the proton translocating NADH dehydrogenase genes (nuoA-N) which are part of the lrhA operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788626, Length=312, Percent_Identity=84.9358974358974, Blast_Score=538, Evalue=1e-154,
Organism=Escherichia coli, GI48994962, Length=151, Percent_Identity=29.8013245033113, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1787806, Length=134, Percent_Identity=31.3432835820896, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1787879, Length=133, Percent_Identity=36.0902255639098, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI145693105, Length=242, Percent_Identity=23.5537190082645, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1788481, Length=237, Percent_Identity=24.8945147679325, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34465; Mature: 34465

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINANRPIINLDLDLLRTFVAVADLNTFAAAAAAVCRTQSAVSQQMQRLEQLVGKELFAR
CCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HGRNKLLSEHGIQLLGYARKILRFNDEACSSLMFSNLQGVLTIGASDESADTILPFLLSR
CCHHHHHHHHCHHHHHHHHHHHHCCHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHH
ISSVYPKLALDVRVKRNAYMVDMVKSQEVDLVVTTNQPHSLDCLNLRTSPTHWYCAAEYV
HHHHCCHHEEEEEECCCEEEEEEECCCCEEEEEECCCCCCEEEEECCCCCCCHHHHHHHH
LQRGEPVPLVLLDDPSPFRDMVLETLNAAGIPWRLAYVASTLLAVRAAVKAGLGVTARPV
HHCCCCCEEEEECCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCH
EMMSPDLRVLGAADGLPPLLDTEYMLCRDPNSQNELAMVIFHAMESYQNPWHYNQFSAEG
HHCCCCCEEEECCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCC
GDDPLMVEGGFE
CCCCEEEECCCC
>Mature Secondary Structure
MINANRPIINLDLDLLRTFVAVADLNTFAAAAAAVCRTQSAVSQQMQRLEQLVGKELFAR
CCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HGRNKLLSEHGIQLLGYARKILRFNDEACSSLMFSNLQGVLTIGASDESADTILPFLLSR
CCHHHHHHHHCHHHHHHHHHHHHCCHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHH
ISSVYPKLALDVRVKRNAYMVDMVKSQEVDLVVTTNQPHSLDCLNLRTSPTHWYCAAEYV
HHHHCCHHEEEEEECCCEEEEEEECCCCEEEEEECCCCCCEEEEECCCCCCCHHHHHHHH
LQRGEPVPLVLLDDPSPFRDMVLETLNAAGIPWRLAYVASTLLAVRAAVKAGLGVTARPV
HHCCCCCEEEEECCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCH
EMMSPDLRVLGAADGLPPLLDTEYMLCRDPNSQNELAMVIFHAMESYQNPWHYNQFSAEG
HHCCCCCEEEECCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCC
GDDPLMVEGGFE
CCCCEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]