Click here to switch to the map view.

The map label for this gene is accD [H]

Identifier: 29141013

GI number: 29141013

Start: 570088

End: 571002

Strand: Direct

Name: accD [H]

Synonym: t0498

Alternate gene names: 29141013

Gene position: 570088-571002 (Clockwise)

Preceding gene: 29141012

Following gene: 29141014

Centisome position: 11.9

GC content: 57.27

Gene sequence:

>915_bases
ATGAGCTGGATTGAACGAATTAAAAGCAACATTACTCCCACCCGCAAGGCAAGCATTCCTGAAGGGGTGTGGACCAAGTG
TGATAGCTGCGGTCAGGTTTTATACCGCGCTGAGCTGGAACGTAATCTTGAGGTCTGTCCTAAGTGTGACCATCATATGC
GCATGTCGGCGCGCAATCGCCTGCATAGCCTGTTAGATGAAGGTTCCCTTGTGGAGTTGGGTAGCGAGCTGGAGCCGAAA
GACGTGCTCAAGTTTCGCGACTCCAAAAAATATAAAGACAGACTGGCGTCCGCGCAGAAAGAAACCGGCGAGAAAGACGC
GCTGGTGGTCATGAAAGGGACGCTTCACGGTATGCCGGTTGTCGCCGCCGCGTTTGAATTCGCGTTCATGGGCGGCTCAA
TGGGGTCTGTCGTTGGCGCACGCTTCGTTCGCGCCGTTGAACAGGCGCTGGAAGACAACTGTCCGTTAGTGTGTTTCTCT
GCTTCCGGCGGCGCGCGTATGCAAGAAGCGCTGATGTCGCTGATGCAGATGGCGAAAACCTCGGCGGCGCTGGCTAAAAT
GCAGGAACGTGGTCTGCCCTACATCTCGGTATTGACCGATCCGACAATGGGCGGCGTTTCCGCCAGTTTTGCGATGCTGG
GCGATCTCAACATCGCCGAGCCAAAAGCCCTGATTGGCTTCGCCGGCCCGCGCGTTATCGAACAAACCGTTCGTGAGAAG
CTCCCGCCAGGATTCCAGCGCAGTGAGTTCCTGATCGAAAAAGGCGCTATTGATATGATAGTCCGCCGTCCGGAAATGCG
CCTGAAGCTGGCGAGCATTCTGGCGAAGCTGATGAATCTGCCCGCGCCGAACCCGGACGCCCCGCGTGAAGGCGTGGTGG
TGCCTCCGGCGCCGGATCAGGAGTCTGAGGCCTGA

Upstream 100 bases:

>100_bases
TATGTTTTAATGTGCAACATTCATGGTCTGTTGGGGGCAAAAATGGCATTATGCGCCCCTTATAATAAAGCTGACTAAGG
TTCAGGCAGAAAGGTCACCA

Downstream 100 bases:

>100_bases
TAACTGAAAAGGGCAGGGCCGCAGGCTCTGCCCTTTTGCTTTTCACCGTAAAGAAGCAGCGGAATCAATGAAAAACAAAT
CTATACCTCAAGCTGCGTCG

Product: acetyl-CoA carboxylase subunit beta

Products: NA

Alternate protein names: ACCase subunit beta; Acetyl-CoA carboxylase carboxyltransferase subunit beta [H]

Number of amino acids: Translated: 304; Mature: 303

Protein sequence:

>304_residues
MSWIERIKSNITPTRKASIPEGVWTKCDSCGQVLYRAELERNLEVCPKCDHHMRMSARNRLHSLLDEGSLVELGSELEPK
DVLKFRDSKKYKDRLASAQKETGEKDALVVMKGTLHGMPVVAAAFEFAFMGGSMGSVVGARFVRAVEQALEDNCPLVCFS
ASGGARMQEALMSLMQMAKTSAALAKMQERGLPYISVLTDPTMGGVSASFAMLGDLNIAEPKALIGFAGPRVIEQTVREK
LPPGFQRSEFLIEKGAIDMIVRRPEMRLKLASILAKLMNLPAPNPDAPREGVVVPPAPDQESEA

Sequences:

>Translated_304_residues
MSWIERIKSNITPTRKASIPEGVWTKCDSCGQVLYRAELERNLEVCPKCDHHMRMSARNRLHSLLDEGSLVELGSELEPK
DVLKFRDSKKYKDRLASAQKETGEKDALVVMKGTLHGMPVVAAAFEFAFMGGSMGSVVGARFVRAVEQALEDNCPLVCFS
ASGGARMQEALMSLMQMAKTSAALAKMQERGLPYISVLTDPTMGGVSASFAMLGDLNIAEPKALIGFAGPRVIEQTVREK
LPPGFQRSEFLIEKGAIDMIVRRPEMRLKLASILAKLMNLPAPNPDAPREGVVVPPAPDQESEA
>Mature_303_residues
SWIERIKSNITPTRKASIPEGVWTKCDSCGQVLYRAELERNLEVCPKCDHHMRMSARNRLHSLLDEGSLVELGSELEPKD
VLKFRDSKKYKDRLASAQKETGEKDALVVMKGTLHGMPVVAAAFEFAFMGGSMGSVVGARFVRAVEQALEDNCPLVCFSA
SGGARMQEALMSLMQMAKTSAALAKMQERGLPYISVLTDPTMGGVSASFAMLGDLNIAEPKALIGFAGPRVIEQTVREKL
PPGFQRSEFLIEKGAIDMIVRRPEMRLKLASILAKLMNLPAPNPDAPREGVVVPPAPDQESEA

Specific function: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA [H

COG id: COG0777

COG function: function code I; Acetyl-CoA carboxylase beta subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AccD/PCCB family [H]

Homologues:

Organism=Homo sapiens, GI119943100, Length=189, Percent_Identity=26.4550264550265, Blast_Score=66, Evalue=3e-11,
Organism=Escherichia coli, GI1788655, Length=304, Percent_Identity=98.0263157894737, Blast_Score=612, Evalue=1e-177,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000438
- InterPro:   IPR000022
- InterPro:   IPR011762 [H]

Pfam domain/function: PF01039 Carboxyl_trans [H]

EC number: =6.4.1.2 [H]

Molecular weight: Translated: 33216; Mature: 33085

Theoretical pI: Translated: 7.81; Mature: 7.81

Prosite motif: PS50980 COA_CT_NTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
5.6 %Met     (Translated Protein)
7.6 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
5.3 %Met     (Mature Protein)
7.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSWIERIKSNITPTRKASIPEGVWTKCDSCGQVLYRAELERNLEVCPKCDHHMRMSARNR
CCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
LHSLLDEGSLVELGSELEPKDVLKFRDSKKYKDRLASAQKETGEKDALVVMKGTLHGMPV
HHHHHCCCCHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHH
VAAAFEFAFMGGSMGSVVGARFVRAVEQALEDNCPLVCFSASGGARMQEALMSLMQMAKT
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHH
SAALAKMQERGLPYISVLTDPTMGGVSASFAMLGDLNIAEPKALIGFAGPRVIEQTVREK
HHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHCCCCCCCCHHHHHCCCHHHHHHHHHHH
LPPGFQRSEFLIEKGAIDMIVRRPEMRLKLASILAKLMNLPAPNPDAPREGVVVPPAPDQ
CCCCCCHHHHHHHCCCHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCCC
ESEA
CCCC
>Mature Secondary Structure 
SWIERIKSNITPTRKASIPEGVWTKCDSCGQVLYRAELERNLEVCPKCDHHMRMSARNR
CHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
LHSLLDEGSLVELGSELEPKDVLKFRDSKKYKDRLASAQKETGEKDALVVMKGTLHGMPV
HHHHHCCCCHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHH
VAAAFEFAFMGGSMGSVVGARFVRAVEQALEDNCPLVCFSASGGARMQEALMSLMQMAKT
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHH
SAALAKMQERGLPYISVLTDPTMGGVSASFAMLGDLNIAEPKALIGFAGPRVIEQTVREK
HHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHCCCCCCCCHHHHHCCCHHHHHHHHHHH
LPPGFQRSEFLIEKGAIDMIVRRPEMRLKLASILAKLMNLPAPNPDAPREGVVVPPAPDQ
CCCCCCHHHHHHHCCCHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCCC
ESEA
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA