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The map label for this gene is eutG [H]

Identifier: 29140924

GI number: 29140924

Start: 471941

End: 473128

Strand: Direct

Name: eutG [H]

Synonym: t0397

Alternate gene names: 29140924

Gene position: 471941-473128 (Clockwise)

Preceding gene: 29140923

Following gene: 29140925

Centisome position: 9.85

GC content: 63.22

Gene sequence:

>1188_bases
ATGCAAGCTGAACTACAGACGGCGCTGTTTCAGGCATTCAACACCCTGAATCTGCAACGGGTGAAAACGTTCAGCGTACC
GCCGGTCACGCTGTGCGGGCTTGGGGCGCTCGGCGCCTGCGGGCAGGAAGCGCAAGCGCGGGGCGTAAGCCATTTGTTTG
TGATGGTCGACAGCTTCCTGCATCAGGCGGGAATGACCGCGCCGCTGGCACGCAGCCTGGCGATGAAAGGCGTGGCGATG
ACGGTCTGGCCGTGTCCGCCAGGCGAGCCGTGCATCACCGATGTCTGCGCGGCGGTGGCGCAACTGCGTGAGGCGGCGTG
CGACGGCGTAGTGGCCTTTGGCGGCGGTTCGGTGTTGGACGCGGCGAAAGCGGTCGCCCTGCTGGTGACTAACCCTGACC
AGACGCTGAGCGCCATGACCGAGCGCAGTACATTACGCCCGCGTCTGCCGCTGATTGCGGTGCCGACCACCGCCGGAACC
GGTTCAGAAACCACCAACGTGACGGTGATTATCGACGCGGTCAGCGGGCGCAAGCAGGTGCTGGCACACGCGTCACTAAT
GCCGGATGTGGCGATTCTTGATGCTGCCGTGACCGAAGGCGTTCCGCCAAATGTGACGGCGATGACCGGTATCGATGCGC
TGACGCATGCGATTGAGGCCTACAGCGCGCTCAACGCCACGCCGTTTACCGACAGCCTGGCGATTGGCGCGATAGCGATG
ATTGGCAAATCGCTGCCGAAGGCCGTCGGCTATGGGCAGGATCTGGCGGCGCGTGAAAATATGTTGCTGGCCTCCTGTAT
GGCGGGAATGGCCTTTTCCAGCGCCGGTCTGGGGCTGTGTCATGCGATGGCGCACCAGCCAGGGGCGGCGCTGCATATTC
CGCACGGCCAGGCCAACGCCATGCTGCTGCCGACAGTCATGGGCTTTAACCGGATGGTATGCCGCGAGCGCTTCAGTCAA
ATCGGTCGGGCGTTAACCAATAAGAAATCGGACGATCGCGATGCGATTGCGGCGGTGTGCGAGCTGATTGCCGAAGTGGG
GCAGAGCAAACGGCTGGCTGACGCTGGCGCCAAACCCGAACACTACAGCGCGTGGGCGCAAGCCGCGCTGGAGGATATTT
GTCTGCGCAGTAACCCACGCACCGCCACACAGGCACAGATTATCGACCTGTACGCGGCTGCCGGGTAA

Upstream 100 bases:

>100_bases
CAGCGTTTCCCGGAGTTACAGGTGCATTTACCGCAGCACAGCCTGTTTATGACCCCGCTGGCGATAGCTAACAGCGGGAG
AGCGAAAGCGGAGGGACTCT

Downstream 100 bases:

>100_bases
TGCTGTAGGCCGGATAAGGTGCTCGCATCGCCATCCGGCAATAACACGGCGTTAATGCCGGAGGCGACGTAAACGTCTTA
TCCGGCTTACAAATCAAAAA

Product: alchohol dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 395; Mature: 395

Protein sequence:

>395_residues
MQAELQTALFQAFNTLNLQRVKTFSVPPVTLCGLGALGACGQEAQARGVSHLFVMVDSFLHQAGMTAPLARSLAMKGVAM
TVWPCPPGEPCITDVCAAVAQLREAACDGVVAFGGGSVLDAAKAVALLVTNPDQTLSAMTERSTLRPRLPLIAVPTTAGT
GSETTNVTVIIDAVSGRKQVLAHASLMPDVAILDAAVTEGVPPNVTAMTGIDALTHAIEAYSALNATPFTDSLAIGAIAM
IGKSLPKAVGYGQDLAARENMLLASCMAGMAFSSAGLGLCHAMAHQPGAALHIPHGQANAMLLPTVMGFNRMVCRERFSQ
IGRALTNKKSDDRDAIAAVCELIAEVGQSKRLADAGAKPEHYSAWAQAALEDICLRSNPRTATQAQIIDLYAAAG

Sequences:

>Translated_395_residues
MQAELQTALFQAFNTLNLQRVKTFSVPPVTLCGLGALGACGQEAQARGVSHLFVMVDSFLHQAGMTAPLARSLAMKGVAM
TVWPCPPGEPCITDVCAAVAQLREAACDGVVAFGGGSVLDAAKAVALLVTNPDQTLSAMTERSTLRPRLPLIAVPTTAGT
GSETTNVTVIIDAVSGRKQVLAHASLMPDVAILDAAVTEGVPPNVTAMTGIDALTHAIEAYSALNATPFTDSLAIGAIAM
IGKSLPKAVGYGQDLAARENMLLASCMAGMAFSSAGLGLCHAMAHQPGAALHIPHGQANAMLLPTVMGFNRMVCRERFSQ
IGRALTNKKSDDRDAIAAVCELIAEVGQSKRLADAGAKPEHYSAWAQAALEDICLRSNPRTATQAQIIDLYAAAG
>Mature_395_residues
MQAELQTALFQAFNTLNLQRVKTFSVPPVTLCGLGALGACGQEAQARGVSHLFVMVDSFLHQAGMTAPLARSLAMKGVAM
TVWPCPPGEPCITDVCAAVAQLREAACDGVVAFGGGSVLDAAKAVALLVTNPDQTLSAMTERSTLRPRLPLIAVPTTAGT
GSETTNVTVIIDAVSGRKQVLAHASLMPDVAILDAAVTEGVPPNVTAMTGIDALTHAIEAYSALNATPFTDSLAIGAIAM
IGKSLPKAVGYGQDLAARENMLLASCMAGMAFSSAGLGLCHAMAHQPGAALHIPHGQANAMLLPTVMGFNRMVCRERFSQ
IGRALTNKKSDDRDAIAAVCELIAEVGQSKRLADAGAKPEHYSAWAQAALEDICLRSNPRTATQAQIIDLYAAAG

Specific function: May act on the acetaldehyde produced from the degradation of ethanolamine [H]

COG id: COG1454

COG function: function code C; Alcohol dehydrogenase, class IV

Gene ontology:

Cell location: Integral Membrane Protein [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI133922590, Length=323, Percent_Identity=28.7925696594427, Blast_Score=103, Evalue=2e-22,
Organism=Escherichia coli, GI87082107, Length=394, Percent_Identity=86.0406091370558, Blast_Score=692, Evalue=0.0,
Organism=Escherichia coli, GI48994951, Length=378, Percent_Identity=35.978835978836, Blast_Score=228, Evalue=4e-61,
Organism=Escherichia coli, GI1789163, Length=372, Percent_Identity=38.1720430107527, Blast_Score=228, Evalue=7e-61,
Organism=Escherichia coli, GI1787493, Length=393, Percent_Identity=31.2977099236641, Blast_Score=177, Evalue=8e-46,
Organism=Escherichia coli, GI1789386, Length=296, Percent_Identity=28.0405405405405, Blast_Score=93, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17537053, Length=305, Percent_Identity=28.1967213114754, Blast_Score=115, Evalue=4e-26,
Organism=Saccharomyces cerevisiae, GI6321181, Length=374, Percent_Identity=33.9572192513369, Blast_Score=214, Evalue=1e-56,
Organism=Drosophila melanogaster, GI24657991, Length=284, Percent_Identity=30.9859154929577, Blast_Score=89, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670
- InterPro:   IPR018211 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: NA

Molecular weight: Translated: 40913; Mature: 40913

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: PS00913 ADH_IRON_1 ; PS00060 ADH_IRON_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQAELQTALFQAFNTLNLQRVKTFSVPPVTLCGLGALGACGQEAQARGVSHLFVMVDSFL
CCHHHHHHHHHHHHCCCHHHEEECCCCCHHHHCCCHHCCCCCHHHHCCHHHHHHHHHHHH
HQAGMTAPLARSLAMKGVAMTVWPCPPGEPCITDVCAAVAQLREAACDGVVAFGGGSVLD
HHCCCCHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCEEEECCCHHHH
AAKAVALLVTNPDQTLSAMTERSTLRPRLPLIAVPTTAGTGSETTNVTVIIDAVSGRKQV
HHHEEEEEEECCHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCEEEEEEECCCCHHHH
LAHASLMPDVAILDAAVTEGVPPNVTAMTGIDALTHAIEAYSALNATPFTDSLAIGAIAM
HHHHHHCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
IGKSLPKAVGYGQDLAARENMLLASCMAGMAFSSAGLGLCHAMAHQPGAALHIPHGQANA
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCEEECCCCCCCC
MLLPTVMGFNRMVCRERFSQIGRALTNKKSDDRDAIAAVCELIAEVGQSKRLADAGAKPE
EEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCHHHCCCCCH
HYSAWAQAALEDICLRSNPRTATQAQIIDLYAAAG
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MQAELQTALFQAFNTLNLQRVKTFSVPPVTLCGLGALGACGQEAQARGVSHLFVMVDSFL
CCHHHHHHHHHHHHCCCHHHEEECCCCCHHHHCCCHHCCCCCHHHHCCHHHHHHHHHHHH
HQAGMTAPLARSLAMKGVAMTVWPCPPGEPCITDVCAAVAQLREAACDGVVAFGGGSVLD
HHCCCCHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCEEEECCCHHHH
AAKAVALLVTNPDQTLSAMTERSTLRPRLPLIAVPTTAGTGSETTNVTVIIDAVSGRKQV
HHHEEEEEEECCHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCEEEEEEECCCCHHHH
LAHASLMPDVAILDAAVTEGVPPNVTAMTGIDALTHAIEAYSALNATPFTDSLAIGAIAM
HHHHHHCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
IGKSLPKAVGYGQDLAARENMLLASCMAGMAFSSAGLGLCHAMAHQPGAALHIPHGQANA
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCEEECCCCCCCC
MLLPTVMGFNRMVCRERFSQIGRALTNKKSDDRDAIAAVCELIAEVGQSKRLADAGAKPE
EEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCHHHCCCCCH
HYSAWAQAALEDICLRSNPRTATQAQIIDLYAAAG
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7868611; 10464203; 11677609 [H]