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The map label for this gene is lspA [H]

Identifier: 29140591

GI number: 29140591

Start: 56686

End: 57186

Strand: Direct

Name: lspA [H]

Synonym: t0049

Alternate gene names: 29140591

Gene position: 56686-57186 (Clockwise)

Preceding gene: 29140590

Following gene: 29140592

Centisome position: 1.18

GC content: 51.7

Gene sequence:

>501_bases
ATGAGTAAACCACTCTGTTCAACAGGACTACGCTGGCTATGGCTGGTAGTAGTCGTGCTGATTATCGATTTGGGCAGCAA
ATACCTGATCCTCCAGAATTTCGCTCTGGGGGATACGGTAGGGCTGTTCCCGTCGCTTAATCTGCATTATGCGCGTAACT
ACGGCGCGGCTTTTAGCTTCCTGGCGGATAGCGGCAGCTGGCAGCGCTGGTTCTTTGCCGGGATTGCGATAGGGATCTGC
GTAATTCTTTTGGTGATGATGTATCGCTCGAAAGCGACGCAGAAGCTGAATAACATCGCTTATGCGCTCATTATTGGCGG
CGCGCTGGGTAATTTGTTCGATCGTCTGTGGCACGGCTTCGTTGTCGATATGATCGATTTTTACGTCGGCGACTGGCATT
TCGCGACGTTCAACCTTGCCGATACGGCAATTTGTATCGGTGCTGCGCTGATAGTACTGGAAGGCTTTTTGCCGAAGCCG
ACAGCGAAAGAGCAGGCATAA

Upstream 100 bases:

>100_bases
ACTACACTACTGATGTCGGCAAGGTGGCGGAACATGCAGATATCTGCGGACGCTGTGTCAGCAACATCGCCGGTAATGGC
GAACAACGTAAATTTGCCTG

Downstream 100 bases:

>100_bases
GCGTAAATACCGGGTTGCGCTTATCCGGTTTTGTAGGCCTGATAAGCGCAGCGCCATCAGGCAAACGTGGTGCCGGATGG
CGGTGAAAACGCCTTATCCG

Product: lipoprotein signal peptidase

Products: NA

Alternate protein names: Prolipoprotein signal peptidase; Signal peptidase II; SPase II [H]

Number of amino acids: Translated: 166; Mature: 165

Protein sequence:

>166_residues
MSKPLCSTGLRWLWLVVVVLIIDLGSKYLILQNFALGDTVGLFPSLNLHYARNYGAAFSFLADSGSWQRWFFAGIAIGIC
VILLVMMYRSKATQKLNNIAYALIIGGALGNLFDRLWHGFVVDMIDFYVGDWHFATFNLADTAICIGAALIVLEGFLPKP
TAKEQA

Sequences:

>Translated_166_residues
MSKPLCSTGLRWLWLVVVVLIIDLGSKYLILQNFALGDTVGLFPSLNLHYARNYGAAFSFLADSGSWQRWFFAGIAIGIC
VILLVMMYRSKATQKLNNIAYALIIGGALGNLFDRLWHGFVVDMIDFYVGDWHFATFNLADTAICIGAALIVLEGFLPKP
TAKEQA
>Mature_165_residues
SKPLCSTGLRWLWLVVVVLIIDLGSKYLILQNFALGDTVGLFPSLNLHYARNYGAAFSFLADSGSWQRWFFAGIAIGICV
ILLVMMYRSKATQKLNNIAYALIIGGALGNLFDRLWHGFVVDMIDFYVGDWHFATFNLADTAICIGAALIVLEGFLPKPT
AKEQA

Specific function: This protein specifically catalyzes the removal of signal peptides from prolipoproteins [H]

COG id: COG0597

COG function: function code MU; Lipoprotein signal peptidase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase A8 family [H]

Homologues:

Organism=Escherichia coli, GI1786210, Length=164, Percent_Identity=92.0731707317073, Blast_Score=306, Evalue=4e-85,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001872 [H]

Pfam domain/function: PF01252 Peptidase_A8 [H]

EC number: =3.4.23.36 [H]

Molecular weight: Translated: 18384; Mature: 18253

Theoretical pI: Translated: 8.06; Mature: 8.06

Prosite motif: PS00855 SPASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKPLCSTGLRWLWLVVVVLIIDLGSKYLILQNFALGDTVGLFPSLNLHYARNYGAAFSF
CCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHCCCCCCCHHHHCCCHHHHH
LADSGSWQRWFFAGIAIGICVILLVMMYRSKATQKLNNIAYALIIGGALGNLFDRLWHGF
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VVDMIDFYVGDWHFATFNLADTAICIGAALIVLEGFLPKPTAKEQA
HHHHHHHHHCCEEEEEECHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
SKPLCSTGLRWLWLVVVVLIIDLGSKYLILQNFALGDTVGLFPSLNLHYARNYGAAFSF
CCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHCCCCCCCHHHHCCCHHHHH
LADSGSWQRWFFAGIAIGICVILLVMMYRSKATQKLNNIAYALIIGGALGNLFDRLWHGF
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VVDMIDFYVGDWHFATFNLADTAICIGAALIVLEGFLPKPTAKEQA
HHHHHHHHHCCEEEEEECHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA