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The map label for this gene is fur [H]

Identifier: 28379623

GI number: 28379623

Start: 2893560

End: 2894042

Strand: Direct

Name: fur [H]

Synonym: lp_3247

Alternate gene names: 28379623

Gene position: 2893560-2894042 (Clockwise)

Preceding gene: 28379621

Following gene: 28379627

Centisome position: 87.46

GC content: 42.44

Gene sequence:

>483_bases
GTGGCAGAAGATATGTTGACCCAAGCCTTGCAGCAATTAAAGGACCATAAAATCCGTGTAACGCCGCAACGGCAAATCAT
TCTTAATTATTTGATTACTCACCATAATCATCCATCCGTCGAAACCATCTATCAGGAATTAGCAACTCAATTACCTAACC
TGAGCTTGGCAACGGTTTACAATACGTTAAAACTTTTTGTCGACTTAGGAATCGTAATTGAATTACAAAATGGCGATGCT
GGCACCCACTATGACTTTTTCGGTCGACCACATTATCACGTCGTTTGTGAGAATTGTGGTAAAATTACTGACGTTTTCGA
ACCCGACCTCCGCAGTGTCGAAGCCAAGGCGGCGGAACTCTCTGGGTACTTGGTTACGGGTCACAATATGGAAGTCTATG
GATTATGCCCAGACTGCCAGAAACTACTCAATGTAACTAAAACAGCTGATTTAAAGCGATTGAAATTGACGCACAGTGAA
TAG

Upstream 100 bases:

>100_bases
AATTTTGTCAAAAGTTTTATCTAGTAATGTTTCTAAATTGGAATCCTTCTAAAAAGTGTGGTTTAATAAGGGTGAATATG
ATAAAAGGAGGAACCGCGTC

Downstream 100 bases:

>100_bases
AACCAGTTCAATGGCAACCGGCTATTTAGCGCGCTGGTTATCCTAAAACAAAAGGAACACTTTCAGTTTTCCTGTATTAG
TCCCTGTCAACCTTAAGTGG

Product: ferric uptake regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 160; Mature: 159

Protein sequence:

>160_residues
MAEDMLTQALQQLKDHKIRVTPQRQIILNYLITHHNHPSVETIYQELATQLPNLSLATVYNTLKLFVDLGIVIELQNGDA
GTHYDFFGRPHYHVVCENCGKITDVFEPDLRSVEAKAAELSGYLVTGHNMEVYGLCPDCQKLLNVTKTADLKRLKLTHSE

Sequences:

>Translated_160_residues
MAEDMLTQALQQLKDHKIRVTPQRQIILNYLITHHNHPSVETIYQELATQLPNLSLATVYNTLKLFVDLGIVIELQNGDA
GTHYDFFGRPHYHVVCENCGKITDVFEPDLRSVEAKAAELSGYLVTGHNMEVYGLCPDCQKLLNVTKTADLKRLKLTHSE
>Mature_159_residues
AEDMLTQALQQLKDHKIRVTPQRQIILNYLITHHNHPSVETIYQELATQLPNLSLATVYNTLKLFVDLGIVIELQNGDAG
THYDFFGRPHYHVVCENCGKITDVFEPDLRSVEAKAAELSGYLVTGHNMEVYGLCPDCQKLLNVTKTADLKRLKLTHSE

Specific function: Manganese-dependent repressor that controls a regulon of oxidative stress resistance and iron-storage proteins. May act as a hydrogen peroxide and organic hydroperoxide sensor [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

None

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 18130; Mature: 17999

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEDMLTQALQQLKDHKIRVTPQRQIILNYLITHHNHPSVETIYQELATQLPNLSLATVY
CCHHHHHHHHHHHHCCCEEECCHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHH
NTLKLFVDLGIVIELQNGDAGTHYDFFGRPHYHVVCENCGKITDVFEPDLRSVEAKAAEL
HHHHHHHCCCEEEEECCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHH
SGYLVTGHNMEVYGLCPDCQKLLNVTKTADLKRLKLTHSE
CCEEEECCCEEEEEECHHHHHHHHHHHCCCHHEEEECCCC
>Mature Secondary Structure 
AEDMLTQALQQLKDHKIRVTPQRQIILNYLITHHNHPSVETIYQELATQLPNLSLATVY
CHHHHHHHHHHHHCCCEEECCHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHH
NTLKLFVDLGIVIELQNGDAGTHYDFFGRPHYHVVCENCGKITDVFEPDLRSVEAKAAEL
HHHHHHHCCCEEEEECCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHH
SGYLVTGHNMEVYGLCPDCQKLLNVTKTADLKRLKLTHSE
CCEEEECCCEEEEEECHHHHHHHHHHHCCCHHEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA