Click here to switch to the map view.

The map label for this gene is ywbI [H]

Identifier: 28379612

GI number: 28379612

Start: 2882390

End: 2883262

Strand: Direct

Name: ywbI [H]

Synonym: lp_3234

Alternate gene names: 28379612

Gene position: 2882390-2883262 (Clockwise)

Preceding gene: 28379607

Following gene: 28379613

Centisome position: 87.13

GC content: 38.6

Gene sequence:

>873_bases
ATGGATTTACAATACTTAGATAACTTTTTAGCTCTCGCCCATTACCGTAGCTTTTCTGCAGCGGCAGATGCCTGTTATAT
CTCACAATCCTCATTTTCAAAACGAATCATGCGTTTAGAAAATAATCTTGGGGTAACACTCTTTGAACGCTCAACCCGTC
AAGTATCATTGACAGAATACGGTCAGATCTATTTGAAATACGCCCAGCAAATTAAAACTTTATCACGCCAAGCAACGGAT
GAAATCAACCGACGTCATGCCGAAGACGAAGGTATTGTCATCGGCGGTATTCCATCTATCAGTGAATATGGAATTTTGGA
TTTGATTTCAGGTTTCATAAAAACAACCCACATTCACTGTCAGGTAAAGTCTGCCCCTTCCGAAGATCTAGAACCCATGC
TACTCAATCAGACTCTAGACTTCGCCTTCATTAAAGAAGTTCACCACACTAATTTATTTTATCAACTTCCCTATGCTGAG
GATCATCTAGTTGCTGTCCTCCCTGCTAATCATCCCTTAGCAAACCTATCTGAAATCAAGCTACAGCAACTAGCGAACGA
AGACTTTATCTTCCAACCAGTTAACTCACGACCATATGAACTTTGCATGATGATTTGCAAACAAAATGGTTTTACACCTA
ATGTTATCTACGCCGATCGTATTATTGAAAATATTCTTAACTTTGTTAAAAAAGGACTAGGTGTTTCTTTGCTCATGGAG
AAATTGGTTCCTAAAGATTCTGAGTTGATCTGCCTTCCTATCCACCCCGCAGTAGTAGCTGACATCAACCTTTGTTATCT
AAAGAAAGAACCTTTAAGTCAGTATGGTTATGCTTTTCTGAATTATTTTTCACATCAAAATAATGCTCGCTAA

Upstream 100 bases:

>100_bases
AGTTTCCATTTGACACGCAATTCTAAGTCTGACTATACTTATTCCAGCAAAGAATAAAGCGATTTCAATTTGTTACAAAT
TTATACGAGGTGGCCTTGCA

Downstream 100 bases:

>100_bases
TAAATATTGCTAAGGTCATGATTATATTTCAGAGGAAGCGCTCACTAATTGGTGCAACAAGGAGCCAAAAAACTTAAATC
TAATCTTGAAAAATTAAATA

Product: transcription regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 290; Mature: 290

Protein sequence:

>290_residues
MDLQYLDNFLALAHYRSFSAAADACYISQSSFSKRIMRLENNLGVTLFERSTRQVSLTEYGQIYLKYAQQIKTLSRQATD
EINRRHAEDEGIVIGGIPSISEYGILDLISGFIKTTHIHCQVKSAPSEDLEPMLLNQTLDFAFIKEVHHTNLFYQLPYAE
DHLVAVLPANHPLANLSEIKLQQLANEDFIFQPVNSRPYELCMMICKQNGFTPNVIYADRIIENILNFVKKGLGVSLLME
KLVPKDSELICLPIHPAVVADINLCYLKKEPLSQYGYAFLNYFSHQNNAR

Sequences:

>Translated_290_residues
MDLQYLDNFLALAHYRSFSAAADACYISQSSFSKRIMRLENNLGVTLFERSTRQVSLTEYGQIYLKYAQQIKTLSRQATD
EINRRHAEDEGIVIGGIPSISEYGILDLISGFIKTTHIHCQVKSAPSEDLEPMLLNQTLDFAFIKEVHHTNLFYQLPYAE
DHLVAVLPANHPLANLSEIKLQQLANEDFIFQPVNSRPYELCMMICKQNGFTPNVIYADRIIENILNFVKKGLGVSLLME
KLVPKDSELICLPIHPAVVADINLCYLKKEPLSQYGYAFLNYFSHQNNAR
>Mature_290_residues
MDLQYLDNFLALAHYRSFSAAADACYISQSSFSKRIMRLENNLGVTLFERSTRQVSLTEYGQIYLKYAQQIKTLSRQATD
EINRRHAEDEGIVIGGIPSISEYGILDLISGFIKTTHIHCQVKSAPSEDLEPMLLNQTLDFAFIKEVHHTNLFYQLPYAE
DHLVAVLPANHPLANLSEIKLQQLANEDFIFQPVNSRPYELCMMICKQNGFTPNVIYADRIIENILNFVKKGLGVSLLME
KLVPKDSELICLPIHPAVVADINLCYLKKEPLSQYGYAFLNYFSHQNNAR

Specific function: Hydrogen Peroxide Sensor. Activates The Expression Of A Regulon Of Hydrogen Peroxide-Inducible Genes Such As Katg, Gor, Ahpc, Ahpf, Oxys (A Regulatory RNA), Dps, Fur And Grxa. Oxyr Expression Is Negatively Autoregulated By Binding To A 43 Bp Region Upstre

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790399, Length=285, Percent_Identity=27.0175438596491, Blast_Score=98, Evalue=6e-22,
Organism=Escherichia coli, GI157672245, Length=271, Percent_Identity=25.0922509225092, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1787879, Length=246, Percent_Identity=29.2682926829268, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1788887, Length=241, Percent_Identity=29.045643153527, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1787530, Length=299, Percent_Identity=24.4147157190635, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI145693105, Length=298, Percent_Identity=25.1677852348993, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI48994962, Length=104, Percent_Identity=37.5, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1788748, Length=295, Percent_Identity=23.0508474576271, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1788481, Length=299, Percent_Identity=24.0802675585284, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33053; Mature: 33053

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLQYLDNFLALAHYRSFSAAADACYISQSSFSKRIMRLENNLGVTLFERSTRQVSLTEY
CCHHHHHHHHHHHHHHHHHHHHHHHEECHHHHHHHHHHHHCCCCEEEEECCCCEEEHHHH
GQIYLKYAQQIKTLSRQATDEINRRHAEDEGIVIGGIPSISEYGILDLISGFIKTTHIHC
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCHHHHHHHHHHHEEEEE
QVKSAPSEDLEPMLLNQTLDFAFIKEVHHTNLFYQLPYAEDHLVAVLPANHPLANLSEIK
EEECCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCEEEEEECCCCCCCHHHHH
LQQLANEDFIFQPVNSRPYELCMMICKQNGFTPNVIYADRIIENILNFVKKGLGVSLLME
HHHHCCCCCEEECCCCCHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHCCCHHHHHH
KLVPKDSELICLPIHPAVVADINLCYLKKEPLSQYGYAFLNYFSHQNNAR
HHCCCCCCEEEEECCCHHHHCCEEEEEECCHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MDLQYLDNFLALAHYRSFSAAADACYISQSSFSKRIMRLENNLGVTLFERSTRQVSLTEY
CCHHHHHHHHHHHHHHHHHHHHHHHEECHHHHHHHHHHHHCCCCEEEEECCCCEEEHHHH
GQIYLKYAQQIKTLSRQATDEINRRHAEDEGIVIGGIPSISEYGILDLISGFIKTTHIHC
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCHHHHHHHHHHHEEEEE
QVKSAPSEDLEPMLLNQTLDFAFIKEVHHTNLFYQLPYAEDHLVAVLPANHPLANLSEIK
EEECCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCEEEEEECCCCCCCHHHHH
LQQLANEDFIFQPVNSRPYELCMMICKQNGFTPNVIYADRIIENILNFVKKGLGVSLLME
HHHHCCCCCEEECCCCCHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHCCCHHHHHH
KLVPKDSELICLPIHPAVVADINLCYLKKEPLSQYGYAFLNYFSHQNNAR
HHCCCCCCEEEEECCCHHHHCCEEEEEECCHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377 [H]