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The map label for this gene is 28379523

Identifier: 28379523

GI number: 28379523

Start: 2771288

End: 2772124

Strand: Direct

Name: 28379523

Synonym: lp_3112

Alternate gene names: NA

Gene position: 2771288-2772124 (Clockwise)

Preceding gene: 28379520

Following gene: 28379524

Centisome position: 83.77

GC content: 47.43

Gene sequence:

>837_bases
ATGCAATCAAAATTAGCTGTTATTATTGGTGGGACTTCTGGCGTTGGTAAACACACCGCAATTGACCTTGCCAACCAAAA
CTATCATGTGATTATCGTCGGCAGTCGGGCTGACAAAGGACGACAGGCTCAAGCCGATATTAGTCAAGCAACTGGCAATC
AGGCTGTCCAATTGGCTTTGGCCGATCTGAGTACCAAAACTGGTGTTCAACAATTTGCTCATCAGCTTGCAGCCATGACG
GATCATATCGATATTCTACTCAATAGTATTGGTGTGATACTACCTGAGCGACATTTATCGGCAGATGGTTATGATTTGAA
CCTAGTTTTAAATTACCTCACCCATTTTTGGACCATTCAAGCCTTGTTACCGTTGCTAAAGCACAGTGACCAAGCGCGCA
TTCTATTGGTTGGTGCCCTGCCATTCGTGATTAACCATGCTAAAGTGAGTCTTCCAGACTTTGACGCCCCGGCCACATCC
AAGTACAATGCCATGACCGTCACAGCCCAGGCCACTGCTGCGCGCGTACTACTCACGTTAGCTCTCAGTGAACGCTTAAC
AGCAACCAACGTGACAATCAACATTTTCCACCCCGGCTATGTCCCAGATTCTAACTTTGGTGCTGGCGGTAGTTGGGTGA
GTCGTTTGGCTGGTCGGATACTGGGTGAAAGTTTCTCTCGCAAAAATTCCCCGATTGGTGCATGGTTAGCTACTGCTCCC
GAACTCACTCACACAAGTGGACACTTCTACGATGACCGCCTACGTCAAGTTCGGTTATCTAAGCAGTACACTCGCTCTAA
GGCCAACGACTTATGGCGACTCAGTTCTCAATATTAA

Upstream 100 bases:

>100_bases
CCAATAACTACTGCACGTCATAATTAATTTAATGCTTGCTATCGGGTCGACCCCATAGTTTATACTTGTGCATAATCATC
GAATTGAAGGAGTGACTGAC

Downstream 100 bases:

>100_bases
GGAGACGCTCTTGTTAACGTTTAAAATTCCTGAGCAACAGCATTACTTCACTACGAAGGAAGTCACCGCGATGACTGGAA
TGACTAAGGATGCGTTACGA

Product: short-chain dehydrogenase/oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 278; Mature: 278

Protein sequence:

>278_residues
MQSKLAVIIGGTSGVGKHTAIDLANQNYHVIIVGSRADKGRQAQADISQATGNQAVQLALADLSTKTGVQQFAHQLAAMT
DHIDILLNSIGVILPERHLSADGYDLNLVLNYLTHFWTIQALLPLLKHSDQARILLVGALPFVINHAKVSLPDFDAPATS
KYNAMTVTAQATAARVLLTLALSERLTATNVTINIFHPGYVPDSNFGAGGSWVSRLAGRILGESFSRKNSPIGAWLATAP
ELTHTSGHFYDDRLRQVRLSKQYTRSKANDLWRLSSQY

Sequences:

>Translated_278_residues
MQSKLAVIIGGTSGVGKHTAIDLANQNYHVIIVGSRADKGRQAQADISQATGNQAVQLALADLSTKTGVQQFAHQLAAMT
DHIDILLNSIGVILPERHLSADGYDLNLVLNYLTHFWTIQALLPLLKHSDQARILLVGALPFVINHAKVSLPDFDAPATS
KYNAMTVTAQATAARVLLTLALSERLTATNVTINIFHPGYVPDSNFGAGGSWVSRLAGRILGESFSRKNSPIGAWLATAP
ELTHTSGHFYDDRLRQVRLSKQYTRSKANDLWRLSSQY
>Mature_278_residues
MQSKLAVIIGGTSGVGKHTAIDLANQNYHVIIVGSRADKGRQAQADISQATGNQAVQLALADLSTKTGVQQFAHQLAAMT
DHIDILLNSIGVILPERHLSADGYDLNLVLNYLTHFWTIQALLPLLKHSDQARILLVGALPFVINHAKVSLPDFDAPATS
KYNAMTVTAQATAARVLLTLALSERLTATNVTINIFHPGYVPDSNFGAGGSWVSRLAGRILGESFSRKNSPIGAWLATAP
ELTHTSGHFYDDRLRQVRLSKQYTRSKANDLWRLSSQY

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI193804850, Length=284, Percent_Identity=30.2816901408451, Blast_Score=112, Evalue=4e-25,
Organism=Homo sapiens, GI225579078, Length=287, Percent_Identity=29.9651567944251, Blast_Score=108, Evalue=4e-24,
Organism=Homo sapiens, GI186928839, Length=279, Percent_Identity=29.0322580645161, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI166795268, Length=198, Percent_Identity=31.3131313131313, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI10190746, Length=299, Percent_Identity=27.7591973244147, Blast_Score=92, Evalue=3e-19,
Organism=Homo sapiens, GI7706523, Length=281, Percent_Identity=25.2669039145907, Blast_Score=88, Evalue=9e-18,
Organism=Homo sapiens, GI19923931, Length=250, Percent_Identity=30.4, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI146231950, Length=201, Percent_Identity=27.8606965174129, Blast_Score=79, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17505416, Length=226, Percent_Identity=24.3362831858407, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI72001364, Length=286, Percent_Identity=25.5244755244755, Blast_Score=77, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI115533172, Length=276, Percent_Identity=26.4492753623188, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI115533174, Length=276, Percent_Identity=26.4492753623188, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17532791, Length=261, Percent_Identity=24.904214559387, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17558006, Length=202, Percent_Identity=27.2277227722772, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17532805, Length=293, Percent_Identity=23.2081911262799, Blast_Score=68, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24586328, Length=282, Percent_Identity=27.6595744680851, Blast_Score=109, Evalue=2e-24,
Organism=Drosophila melanogaster, GI45554248, Length=285, Percent_Identity=28.7719298245614, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24640117, Length=285, Percent_Identity=28.7719298245614, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI28573296, Length=282, Percent_Identity=26.9503546099291, Blast_Score=101, Evalue=5e-22,
Organism=Drosophila melanogaster, GI22024069, Length=198, Percent_Identity=30.8080808080808, Blast_Score=101, Evalue=6e-22,
Organism=Drosophila melanogaster, GI19921754, Length=198, Percent_Identity=29.7979797979798, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI45553409, Length=285, Percent_Identity=27.0175438596491, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24647948, Length=285, Percent_Identity=27.0175438596491, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24647946, Length=260, Percent_Identity=28.4615384615385, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI161076371, Length=256, Percent_Identity=26.953125, Blast_Score=94, Evalue=7e-20,
Organism=Drosophila melanogaster, GI24647931, Length=281, Percent_Identity=28.1138790035587, Blast_Score=88, Evalue=7e-18,
Organism=Drosophila melanogaster, GI20129347, Length=289, Percent_Identity=24.9134948096886, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24656154, Length=214, Percent_Identity=28.9719626168224, Blast_Score=65, Evalue=7e-11,
Organism=Drosophila melanogaster, GI19922628, Length=214, Percent_Identity=28.9719626168224, Blast_Score=65, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: NA

Molecular weight: Translated: 30204; Mature: 30204

Theoretical pI: Translated: 9.87; Mature: 9.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSKLAVIIGGTSGVGKHTAIDLANQNYHVIIVGSRADKGRQAQADISQATGNQAVQLAL
CCCCEEEEEECCCCCCCCEEEEECCCCEEEEEEECCCCCCCCHHHHHHHCCCCCEEEEEE
ADLSTKTGVQQFAHQLAAMTDHIDILLNSIGVILPERHLSADGYDLNLVLNYLTHFWTIQ
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCHHHHHHHHHHHHHHHH
ALLPLLKHSDQARILLVGALPFVINHAKVSLPDFDAPATSKYNAMTVTAQATAARVLLTL
HHHHHHHCCCCCEEEEEECHHHHHCCCEEECCCCCCCCCCCCCEEEEEEHHHHHHHHHHH
ALSERLTATNVTINIFHPGYVPDSNFGAGGSWVSRLAGRILGESFSRKNSPIGAWLATAP
HHHHCEEEEEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCC
ELTHTSGHFYDDRLRQVRLSKQYTRSKANDLWRLSSQY
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MQSKLAVIIGGTSGVGKHTAIDLANQNYHVIIVGSRADKGRQAQADISQATGNQAVQLAL
CCCCEEEEEECCCCCCCCEEEEECCCCEEEEEEECCCCCCCCHHHHHHHCCCCCEEEEEE
ADLSTKTGVQQFAHQLAAMTDHIDILLNSIGVILPERHLSADGYDLNLVLNYLTHFWTIQ
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCHHHHHHHHHHHHHHHH
ALLPLLKHSDQARILLVGALPFVINHAKVSLPDFDAPATSKYNAMTVTAQATAARVLLTL
HHHHHHHCCCCCEEEEEECHHHHHCCCEEECCCCCCCCCCCCCEEEEEEHHHHHHHHHHH
ALSERLTATNVTINIFHPGYVPDSNFGAGGSWVSRLAGRILGESFSRKNSPIGAWLATAP
HHHHCEEEEEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCC
ELTHTSGHFYDDRLRQVRLSKQYTRSKANDLWRLSSQY
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8383668 [H]