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The map label for this gene is oxyR [H]

Identifier: 28379389

GI number: 28379389

Start: 2619990

End: 2620892

Strand: Direct

Name: oxyR [H]

Synonym: lp_2942

Alternate gene names: 28379389

Gene position: 2619990-2620892 (Clockwise)

Preceding gene: 28379385

Following gene: 28379392

Centisome position: 79.2

GC content: 45.85

Gene sequence:

>903_bases
ATGACCATTAATGACCTCCAAGCATTCGTGATGGTGTACGATTTACGCCACATTTCTAACGCTGCCGTAGAACTCCACTT
ATCACAATCGGAATTGTCCAAACGAATGCGAGCCCTTGAGAACGAACTGAACATTAAACTACTAGATACACACAACAAGC
GCCGTCTACAAATCACGCCAGCTGGTGAAACGTTCTATCATCATGCGCATAAAATGATTACAGACTATGAGACCATGATG
CACGATTTGGCACCGAATCGGCCAACGACATTTGCCAAGCTCATCATTGGCGCCATTCCAATCTCAGGTCAATATAACAT
TGCCAAAAAGATCGCCACTTTTGATACTCAGCATCCTGATACTGAAATCAAAATCATCGAGGATGAGGGCGACCAAATCG
TCAAACGGTTACTGAGTGGTGAGCTACAAGCGGCCATCATTCGCGATACTCAGACGACCCAATTGCAACCCACCGAATTT
CAAAAACAACCACTACTCGCTGACGAACTCAAAATTATTTTACCGCGTGATCACCCCCTAGCTACCCAGCCAGTCATTCG
GATTCAAGACTTAGCGCGGCAGAAAATTGCAACGTTACCACCGGGCTCCGGTGTTTACGAACCGATCAACGCACTCTTTG
CTCAGCAAGGCATGACGCCCCAATTCTTCTTTGAAAGTACGCATATTGAAACGCTCCTGGGCATTCTCAATCAAAATAAC
GTGACTTTCTTATTTAAACAATCGGTACTTCCGTTCATGACTGAACACGTGGTCATGCGCTCACTCGCCATCCCGTTCAT
CAGTCAACTGAACTTTGTATATCCCCAGCGAACGGGGAACCAGTTACTCACCGACTTAATTGACTACTTGACGGTGACTG
CCCAGGAAAATCAACAAGTTTAA

Upstream 100 bases:

>100_bases
GGCCTCACAATATTGATACTAATTTATACCGTTACTTAATTAGGTGGGCCCCGCCATCGGTGTTAGAATAGAATTTAACC
TAAAGAAAAGTGTGACTGCT

Downstream 100 bases:

>100_bases
AAAACACCCTTTCCATCCGACCAACCGGCCGTTTGAAAAGGGTATTTTTTAAACTTATCCGCTTATGCCAACCCAACGAG
GTGGAACCAGAACATCTCAA

Product: transcription regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 300; Mature: 299

Protein sequence:

>300_residues
MTINDLQAFVMVYDLRHISNAAVELHLSQSELSKRMRALENELNIKLLDTHNKRRLQITPAGETFYHHAHKMITDYETMM
HDLAPNRPTTFAKLIIGAIPISGQYNIAKKIATFDTQHPDTEIKIIEDEGDQIVKRLLSGELQAAIIRDTQTTQLQPTEF
QKQPLLADELKIILPRDHPLATQPVIRIQDLARQKIATLPPGSGVYEPINALFAQQGMTPQFFFESTHIETLLGILNQNN
VTFLFKQSVLPFMTEHVVMRSLAIPFISQLNFVYPQRTGNQLLTDLIDYLTVTAQENQQV

Sequences:

>Translated_300_residues
MTINDLQAFVMVYDLRHISNAAVELHLSQSELSKRMRALENELNIKLLDTHNKRRLQITPAGETFYHHAHKMITDYETMM
HDLAPNRPTTFAKLIIGAIPISGQYNIAKKIATFDTQHPDTEIKIIEDEGDQIVKRLLSGELQAAIIRDTQTTQLQPTEF
QKQPLLADELKIILPRDHPLATQPVIRIQDLARQKIATLPPGSGVYEPINALFAQQGMTPQFFFESTHIETLLGILNQNN
VTFLFKQSVLPFMTEHVVMRSLAIPFISQLNFVYPQRTGNQLLTDLIDYLTVTAQENQQV
>Mature_299_residues
TINDLQAFVMVYDLRHISNAAVELHLSQSELSKRMRALENELNIKLLDTHNKRRLQITPAGETFYHHAHKMITDYETMMH
DLAPNRPTTFAKLIIGAIPISGQYNIAKKIATFDTQHPDTEIKIIEDEGDQIVKRLLSGELQAAIIRDTQTTQLQPTEFQ
KQPLLADELKIILPRDHPLATQPVIRIQDLARQKIATLPPGSGVYEPINALFAQQGMTPQFFFESTHIETLLGILNQNNV
TFLFKQSVLPFMTEHVVMRSLAIPFISQLNFVYPQRTGNQLLTDLIDYLTVTAQENQQV

Specific function: Required for the induction of a regulon of hydrogen peroxide inducible genes such as catalase and glutathione- reductase [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790399, Length=252, Percent_Identity=26.5873015873016, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI145693105, Length=234, Percent_Identity=22.2222222222222, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1788887, Length=280, Percent_Identity=29.2857142857143, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI157672245, Length=278, Percent_Identity=24.4604316546763, Blast_Score=81, Evalue=9e-17,
Organism=Escherichia coli, GI1787879, Length=288, Percent_Identity=23.6111111111111, Blast_Score=77, Evalue=9e-16,
Organism=Escherichia coli, GI1787806, Length=256, Percent_Identity=22.65625, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1787530, Length=216, Percent_Identity=24.0740740740741, Blast_Score=68, Evalue=9e-13,
Organism=Escherichia coli, GI1787601, Length=223, Percent_Identity=26.457399103139, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34176; Mature: 34045

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTINDLQAFVMVYDLRHISNAAVELHLSQSELSKRMRALENELNIKLLDTHNKRRLQITP
CCHHHHHHHHHHHHHHHHCCEEEEEEECHHHHHHHHHHHHHHCCEEEEECCCCEEEEEEC
AGETFYHHAHKMITDYETMMHDLAPNRPTTFAKLIIGAIPISGQYNIAKKIATFDTQHPD
CCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCC
TEIKIIEDEGDQIVKRLLSGELQAAIIRDTQTTQLQPTEFQKQPLLADELKIILPRDHPL
CEEEEEECCHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHCCCCCHHCEEEEECCCCCC
ATQPVIRIQDLARQKIATLPPGSGVYEPINALFAQQGMTPQFFFESTHIETLLGILNQNN
CCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCHHHEECHHHHHHHHHHHCCCC
VTFLFKQSVLPFMTEHVVMRSLAIPFISQLNFVYPQRTGNQLLTDLIDYLTVTAQENQQV
EEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHEEECCCCCCC
>Mature Secondary Structure 
TINDLQAFVMVYDLRHISNAAVELHLSQSELSKRMRALENELNIKLLDTHNKRRLQITP
CHHHHHHHHHHHHHHHHCCEEEEEEECHHHHHHHHHHHHHHCCEEEEECCCCEEEEEEC
AGETFYHHAHKMITDYETMMHDLAPNRPTTFAKLIIGAIPISGQYNIAKKIATFDTQHPD
CCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCC
TEIKIIEDEGDQIVKRLLSGELQAAIIRDTQTTQLQPTEFQKQPLLADELKIILPRDHPL
CEEEEEECCHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHCCCCCHHCEEEEECCCCCC
ATQPVIRIQDLARQKIATLPPGSGVYEPINALFAQQGMTPQFFFESTHIETLLGILNQNN
CCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCHHHEECHHHHHHHHHHHCCCC
VTFLFKQSVLPFMTEHVVMRSLAIPFISQLNFVYPQRTGNQLLTDLIDYLTVTAQENQQV
EEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA