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The map label for this gene is sip1 [H]

Identifier: 28379329

GI number: 28379329

Start: 2551838

End: 2552455

Strand: Direct

Name: sip1 [H]

Synonym: lp_2862

Alternate gene names: 28379329

Gene position: 2551838-2552455 (Clockwise)

Preceding gene: 28379324

Following gene: 28379330

Centisome position: 77.14

GC content: 46.28

Gene sequence:

>618_bases
TTGAAAACATTTAAAAGCATTATGAGCTGGGTGGTTCCGATTGCGATTGGCTTGATCATCGCCCTACTGATTCGTCAGTT
CTGGTTTACTATGGTCAAAGTCGATGGGACTTCGATGCAACCGAATTTACAAAATAACGAACGCGTCGTAGCTTTTAAGA
CTAGCAAAATCAAAGCAGGTTCCGTCGTCGTCTTCAACGCCTACGGACTCGATCCGAACCAGACCGACAAAAACGCCGTT
TATGTTAAGCGGGTCATTGGGATGCCTGGGGATACGGTCCGCTACACAAGTTCCGGTAAACTTTACGTGAACAACAAATT
AGTCAAGCAAACCTACCTCAAAAATAAGTATCAACAAACGACTGGGTCCTTCATGGCTAATAGTCACAGCAAGTTCACTG
GTTGGACACTCAATAGTTTGAGCCATGATCAAGGCTGGGCCAAGTCCGTGACCAACAATACGGTGCCGAAGGGTTACTAC
TTTGTCCTTGGTGATCACCGGAGCGTCTCTAACGATGGCCGTTACTGGGGGCTCGTTCCTAAGAGCAAGATGATTGGGGT
CGTCAAAGCATGGCCATGGCAGAACCGCAAACAATATATTAATAACTACCAACCTTAA

Upstream 100 bases:

>100_bases
CATTTTGAGTATCGTTGAACTTTTAAGCTTTTTTATACTGCGAAAAAATCATTATCGTTTATAATGAGAGGTATACACAC
AATTAAGGGAGTTTTAACCA

Downstream 100 bases:

>100_bases
GATTTGAACACCTTATCAGCAAGTCGTTAACTGCGACTTGCTTTTTGTTATACTGAAAATATTATTTAAATAATAAGGAG
CCTAATCAATGACCACCAAA

Product: signal peptidase I

Products: NA

Alternate protein names: SPase IB; Leader peptidase IB [H]

Number of amino acids: Translated: 205; Mature: 205

Protein sequence:

>205_residues
MKTFKSIMSWVVPIAIGLIIALLIRQFWFTMVKVDGTSMQPNLQNNERVVAFKTSKIKAGSVVVFNAYGLDPNQTDKNAV
YVKRVIGMPGDTVRYTSSGKLYVNNKLVKQTYLKNKYQQTTGSFMANSHSKFTGWTLNSLSHDQGWAKSVTNNTVPKGYY
FVLGDHRSVSNDGRYWGLVPKSKMIGVVKAWPWQNRKQYINNYQP

Sequences:

>Translated_205_residues
MKTFKSIMSWVVPIAIGLIIALLIRQFWFTMVKVDGTSMQPNLQNNERVVAFKTSKIKAGSVVVFNAYGLDPNQTDKNAV
YVKRVIGMPGDTVRYTSSGKLYVNNKLVKQTYLKNKYQQTTGSFMANSHSKFTGWTLNSLSHDQGWAKSVTNNTVPKGYY
FVLGDHRSVSNDGRYWGLVPKSKMIGVVKAWPWQNRKQYINNYQP
>Mature_205_residues
MKTFKSIMSWVVPIAIGLIIALLIRQFWFTMVKVDGTSMQPNLQNNERVVAFKTSKIKAGSVVVFNAYGLDPNQTDKNAV
YVKRVIGMPGDTVRYTSSGKLYVNNKLVKQTYLKNKYQQTTGSFMANSHSKFTGWTLNSLSHDQGWAKSVTNNTVPKGYY
FVLGDHRSVSNDGRYWGLVPKSKMIGVVKAWPWQNRKQYINNYQP

Specific function: Essential for cell viability [H]

COG id: COG0681

COG function: function code U; Signal peptidase I

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S26 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000223
- InterPro:   IPR019758
- InterPro:   IPR019757
- InterPro:   IPR019756
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056 [H]

Pfam domain/function: PF00717 Peptidase_S24 [H]

EC number: =3.4.21.89 [H]

Molecular weight: Translated: 23316; Mature: 23316

Theoretical pI: Translated: 10.72; Mature: 10.72

Prosite motif: PS00760 SPASE_I_2 ; PS00761 SPASE_I_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTFKSIMSWVVPIAIGLIIALLIRQFWFTMVKVDGTSMQPNLQNNERVVAFKTSKIKAG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCCEEEEEECCCCCCC
SVVVFNAYGLDPNQTDKNAVYVKRVIGMPGDTVRYTSSGKLYVNNKLVKQTYLKNKYQQT
CEEEEEEECCCCCCCCCCCEEEEHHHCCCCCCEEEECCCEEEECCHHHHHHHHHHHHHHH
TGSFMANSHSKFTGWTLNSLSHDQGWAKSVTNNTVPKGYYFVLGDHRSVSNDGRYWGLVP
HHHHHHCCCCCCCCEEECCCCCCCCHHHHHCCCCCCCCEEEEEECCCCCCCCCCEEEECC
KSKMIGVVKAWPWQNRKQYINNYQP
CHHHEEEEECCCCCCHHHHHCCCCC
>Mature Secondary Structure
MKTFKSIMSWVVPIAIGLIIALLIRQFWFTMVKVDGTSMQPNLQNNERVVAFKTSKIKAG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCCEEEEEECCCCCCC
SVVVFNAYGLDPNQTDKNAVYVKRVIGMPGDTVRYTSSGKLYVNNKLVKQTYLKNKYQQT
CEEEEEEECCCCCCCCCCCEEEEHHHCCCCCCEEEECCCEEEECCHHHHHHHHHHHHHHH
TGSFMANSHSKFTGWTLNSLSHDQGWAKSVTNNTVPKGYYFVLGDHRSVSNDGRYWGLVP
HHHHHHCCCCCCCCEEECCCCCCCCHHHHHCCCCCCCCEEEEEECCCCCCCCCCEEEECC
KSKMIGVVKAWPWQNRKQYINNYQP
CHHHEEEEECCCCCCHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA