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The map label for this gene is ycaM [H]

Identifier: 28379282

GI number: 28379282

Start: 2493046

End: 2494482

Strand: Direct

Name: ycaM [H]

Synonym: lp_2799

Alternate gene names: 28379282

Gene position: 2493046-2494482 (Clockwise)

Preceding gene: 28379277

Following gene: 28379283

Centisome position: 75.36

GC content: 45.23

Gene sequence:

>1437_bases
ATGGCAAACGAAAAACAACTTCGATGGTCCAACATTGCTTTAATTGCATTCGTGGCGGTCTGGGGCCTAGGTAACGTTGT
CAATAATTTTGCGTTACAAGGGCTTTCAGTCGTCACTTCTTGGATTTTGATCATGATTATTTATTTTATTCCCTACACCT
TGATTGTGGGTCAACTGGGTTCGACCTTTAAGGATGCTGAGGGGGGCGTCTCATCTTGGATTCGAGCAACGAGTACCAAG
CGCCTAGCTTACTATGCTGCCTGGACTTATTGGATCGTGCACATTCCGTACTTAGCACAAAAACCCCAAGGGATTCTAAT
TGCATTCAGCTGGCTGTTCCGCGGTAATGGGAACTTCGTCAACACGACACCTGCGTTAGTCGTTCAAGCCATTTGTTTAG
TGCTATTCTTATTCTTCCTCTGGATTGCTTCATTGGGACTAACGACACTGAAACGCATCGGGAGCGTTGCTGGTACGGGG
ATGTTCATCATGTCGATTTTATTCATCATCTTGGCCGTATCAGCACCGTTTATGACCAAGGCGACTGTTCAGACACCGAA
CATGTTTTCACTCAAGTCCTACTTACCTAAGTTTGACTTTACCTACTTTACGACCGTTTCAATGTTAGTCTTCGCGGTCG
GGGGATCTGAAAAGATTTCGCCGTACGTTAATAAAACCAAAAATCCGGGACGTGAGTTTCCGTTAGGCATGTTAGTGCTC
GCAGGTATGGTCGCAATCTGTGCCCTGCTGGGTTCATTTGCCATGGGGATTCTGTTTAACTCCAAGCACATTCCCGCTGA
TTTGATGGCCAACGGTGCTTACTACGCGTTTCAACGACTAGGTGCCTTCTACCACGTGGGCAATCTGTTCTTGATCCTCT
ACGCAATTGCCAATGTGCTTGCCCAAATCTCCGCCTTAGCGTTCTCAATCGATGCGCCATTGAAGATTTTGCTTGGTGAT
GCCGACCCTGAATTTATTCCCAAAAAATTAAGTAAAATGAACAAGAAGGATGTGCCCGTCAACGGTTACATCTTAACTGG
GGTTTTGGTCAGCATTCTCATTATCATTCCTGCATTAGGGATTGGAAACATGAATGAACTCTTTAATTGGTTATTGAACT
TAAATTCGGTCGTAATGCCGATGCGCTACCTGTGGGTCTTTCTAGCTTACATGCTACTCAACAAGCACTTAAAGGAATTC
AAGAGTGATTACAAGTTCCTGAAAAACCCAGTCGCTGGCCGTTTGGTCGGTGCTTGGTGCTTCCTGTTTACAGCATTTGC
TTGCATCCTCGGAATGGTTCCAAAGACTTCCTACGCTAGCAATCCTAGCAGTTGGCTCTTCCAACTGACTTTAAATATTC
TAACGCCAATTATCTTTGTTGCCTTAGGGATGATTTTGCCGATGATTGCTCGTCGTCATCGCACTAAAACCGCTTAG

Upstream 100 bases:

>100_bases
TTAAAATTTAAAGCGCTTTTAATATTAACTTGTTAATACTGGCATCGCTTTCAGTTTGGCCTTACAATTAAGCATACTTT
AGCTCACAAAGGAGTTCAAC

Downstream 100 bases:

>100_bases
TGCGTCACCGATCTTTACGCCCGCATCGTCGCTCTACGCCTGCGGACTCACTGACTTTTTTGTAACGTTGATCGATAATC
TATTCGCCACCGCTGACAGC

Product: amino acid transport protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 478; Mature: 477

Protein sequence:

>478_residues
MANEKQLRWSNIALIAFVAVWGLGNVVNNFALQGLSVVTSWILIMIIYFIPYTLIVGQLGSTFKDAEGGVSSWIRATSTK
RLAYYAAWTYWIVHIPYLAQKPQGILIAFSWLFRGNGNFVNTTPALVVQAICLVLFLFFLWIASLGLTTLKRIGSVAGTG
MFIMSILFIILAVSAPFMTKATVQTPNMFSLKSYLPKFDFTYFTTVSMLVFAVGGSEKISPYVNKTKNPGREFPLGMLVL
AGMVAICALLGSFAMGILFNSKHIPADLMANGAYYAFQRLGAFYHVGNLFLILYAIANVLAQISALAFSIDAPLKILLGD
ADPEFIPKKLSKMNKKDVPVNGYILTGVLVSILIIIPALGIGNMNELFNWLLNLNSVVMPMRYLWVFLAYMLLNKHLKEF
KSDYKFLKNPVAGRLVGAWCFLFTAFACILGMVPKTSYASNPSSWLFQLTLNILTPIIFVALGMILPMIARRHRTKTA

Sequences:

>Translated_478_residues
MANEKQLRWSNIALIAFVAVWGLGNVVNNFALQGLSVVTSWILIMIIYFIPYTLIVGQLGSTFKDAEGGVSSWIRATSTK
RLAYYAAWTYWIVHIPYLAQKPQGILIAFSWLFRGNGNFVNTTPALVVQAICLVLFLFFLWIASLGLTTLKRIGSVAGTG
MFIMSILFIILAVSAPFMTKATVQTPNMFSLKSYLPKFDFTYFTTVSMLVFAVGGSEKISPYVNKTKNPGREFPLGMLVL
AGMVAICALLGSFAMGILFNSKHIPADLMANGAYYAFQRLGAFYHVGNLFLILYAIANVLAQISALAFSIDAPLKILLGD
ADPEFIPKKLSKMNKKDVPVNGYILTGVLVSILIIIPALGIGNMNELFNWLLNLNSVVMPMRYLWVFLAYMLLNKHLKEF
KSDYKFLKNPVAGRLVGAWCFLFTAFACILGMVPKTSYASNPSSWLFQLTLNILTPIIFVALGMILPMIARRHRTKTA
>Mature_477_residues
ANEKQLRWSNIALIAFVAVWGLGNVVNNFALQGLSVVTSWILIMIIYFIPYTLIVGQLGSTFKDAEGGVSSWIRATSTKR
LAYYAAWTYWIVHIPYLAQKPQGILIAFSWLFRGNGNFVNTTPALVVQAICLVLFLFFLWIASLGLTTLKRIGSVAGTGM
FIMSILFIILAVSAPFMTKATVQTPNMFSLKSYLPKFDFTYFTTVSMLVFAVGGSEKISPYVNKTKNPGREFPLGMLVLA
GMVAICALLGSFAMGILFNSKHIPADLMANGAYYAFQRLGAFYHVGNLFLILYAIANVLAQISALAFSIDAPLKILLGDA
DPEFIPKKLSKMNKKDVPVNGYILTGVLVSILIIIPALGIGNMNELFNWLLNLNSVVMPMRYLWVFLAYMLLNKHLKEFK
SDYKFLKNPVAGRLVGAWCFLFTAFACILGMVPKTSYASNPSSWLFQLTLNILTPIIFVALGMILPMIARRHRTKTA

Specific function: Unknown

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Escherichia coli, GI87081798, Length=474, Percent_Identity=58.0168776371308, Blast_Score=592, Evalue=1e-170,
Organism=Escherichia coli, GI48994921, Length=393, Percent_Identity=25.6997455470738, Blast_Score=125, Evalue=4e-30,
Organism=Escherichia coli, GI87082380, Length=413, Percent_Identity=21.7917675544794, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1787768, Length=394, Percent_Identity=28.4263959390863, Blast_Score=77, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 53003; Mature: 52872

Theoretical pI: Translated: 10.30; Mature: 10.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANEKQLRWSNIALIAFVAVWGLGNVVNNFALQGLSVVTSWILIMIIYFIPYTLIVGQLG
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
STFKDAEGGVSSWIRATSTKRLAYYAAWTYWIVHIPYLAQKPQGILIAFSWLFRGNGNFV
CCHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEHHCCCCCEE
NTTPALVVQAICLVLFLFFLWIASLGLTTLKRIGSVAGTGMFIMSILFIILAVSAPFMTK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCC
ATVQTPNMFSLKSYLPKFDFTYFTTVSMLVFAVGGSEKISPYVNKTKNPGREFPLGMLVL
CCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCCCCCHHHHHH
AGMVAICALLGSFAMGILFNSKHIPADLMANGAYYAFQRLGAFYHVGNLFLILYAIANVL
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AQISALAFSIDAPLKILLGDADPEFIPKKLSKMNKKDVPVNGYILTGVLVSILIIIPALG
HHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHCCCCCCCCCCEEHHHHHHHHHHHHHCCC
IGNMNELFNWLLNLNSVVMPMRYLWVFLAYMLLNKHLKEFKSDYKFLKNPVAGRLVGAWC
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
FLFTAFACILGMVPKTSYASNPSSWLFQLTLNILTPIIFVALGMILPMIARRHRTKTA
HHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
ANEKQLRWSNIALIAFVAVWGLGNVVNNFALQGLSVVTSWILIMIIYFIPYTLIVGQLG
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
STFKDAEGGVSSWIRATSTKRLAYYAAWTYWIVHIPYLAQKPQGILIAFSWLFRGNGNFV
CCHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEHHCCCCCEE
NTTPALVVQAICLVLFLFFLWIASLGLTTLKRIGSVAGTGMFIMSILFIILAVSAPFMTK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCC
ATVQTPNMFSLKSYLPKFDFTYFTTVSMLVFAVGGSEKISPYVNKTKNPGREFPLGMLVL
CCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCCCCCHHHHHH
AGMVAICALLGSFAMGILFNSKHIPADLMANGAYYAFQRLGAFYHVGNLFLILYAIANVL
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AQISALAFSIDAPLKILLGDADPEFIPKKLSKMNKKDVPVNGYILTGVLVSILIIIPALG
HHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHCCCCCCCCCCEEHHHHHHHHHHHHHCCC
IGNMNELFNWLLNLNSVVMPMRYLWVFLAYMLLNKHLKEFKSDYKFLKNPVAGRLVGAWC
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
FLFTAFACILGMVPKTSYASNPSSWLFQLTLNILTPIIFVALGMILPMIARRHRTKTA
HHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]