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The map label for this gene is aspB [C]

Identifier: 28378420

GI number: 28378420

Start: 1578264

End: 1579469

Strand: Direct

Name: aspB [C]

Synonym: lp_1739

Alternate gene names: 28378420

Gene position: 1578264-1579469 (Clockwise)

Preceding gene: 28378419

Following gene: 28378421

Centisome position: 47.71

GC content: 46.27

Gene sequence:

>1206_bases
ATGTACATGGAATTATCGCGTAAAGTAATGCAGGTTCAACCGTCAGCGACATTGAAGATCAGTGCGACTGCCAAGCAAAT
GATGGCGGACGGCGTTGACGTTATCAATTTAGGAATCGGTGAACCGGATTTTCAGACCCCGGATAACATTAAGCAAGCAG
CCATTGATAGTATTCAAAATGGTCAAGCGAGTTTCTACACACCGGCAACTGGATTACCAGCTTTAAAACAAGCCATCAGT
CAGCGAATTGAGGCTGACCATCACTACCATTTTGATCCTAATCAGATCGTCGTAACGGATGGCGCAAAAATGGCGTTGTT
TACGTTATTCCAAGTTATTCTGAATCCCGACGATGAAGTGTTATTACCAGTCCCATACTGGGTCAGCTATTCGGAGCAAG
TTAAATTAGCTGGTGGTGTGCCAGTCGAAGTTAGCACCGATGAACAGTTGCGGTTTACCACTGCTGATTTGGAAGCGCAG
CGGACGCCTAAGACGAAGGCCTTAGTCTTGAATTCGCCACAGAATCCATCCGGTCTGGTTTTCAGCCGTGCAGAATTGAC
GGCGATCGTGAATTGGGCCGTTGAACACGACGTTTTGGTAATTGCGGATGAAATTTATGAAAAGTTATTATATAACGGTA
ATGAATTTACATCCGTGTTAGAATTAGATGATGCTAATATGGATCACGTGGTTTTGATCAATGGGGTTTCAAAAGCCTAT
TCCATGACTGGTTGGCGTATCGGATATGCTGCCGGGCCACAAACCATCATGGCTAAGATGGGGGTCGTGTTAGGTCACGC
TGCTAGCAACCCAGCCGCCGTATCACAATATGCTGCGATTGAAGCTTTTAGTGGTGACCAATCATCGGTTGAAACGATGC
GTCAGGGCTTTGAAGCGCGGTTAAACGAACTATACCCACTGATCGAGCGTTTACCTGGGTTTAAGATGCCTGCTGGCAAA
CCAGCGGGAGCCTTTTACTTGTTCCCAGATATTACGGAAGCATTGCGTTTAACAGGCTATGCAGATGCACCGGCCTTTGT
GACGGCAGTGTTATTAGAAGCCCATGTCGGTTTAGTGCCTGGAGAGGCGTTTGGCATGCCCGGTTGTTTACGGTTAAGCT
ATGCAACTGATATCGATTCCTTGCGAGAGGCCCATCGACGGTTACAAAAATTTATGACAGAAAAAATTGCTGAACAAGCA
AAGTAA

Upstream 100 bases:

>100_bases
TACTTGAACCAGAAAAAGAATTTATGTTATGAAATTTTGCAGTATTCTAATGGAAACCAGCTGAAATCAATTATTAACAT
TTAAGGTTAAAGGAGTGCGG

Downstream 100 bases:

>100_bases
TTGGAGGATGTAAGTAAATGGTGCAACAGATCAACATTATCGATGCTAAGGACCATGTCGACGAAAAAGTAAAGATTGGG
GCTTGGCTCACTAATAAACG

Product: aspartate aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 401; Mature: 401

Protein sequence:

>401_residues
MYMELSRKVMQVQPSATLKISATAKQMMADGVDVINLGIGEPDFQTPDNIKQAAIDSIQNGQASFYTPATGLPALKQAIS
QRIEADHHYHFDPNQIVVTDGAKMALFTLFQVILNPDDEVLLPVPYWVSYSEQVKLAGGVPVEVSTDEQLRFTTADLEAQ
RTPKTKALVLNSPQNPSGLVFSRAELTAIVNWAVEHDVLVIADEIYEKLLYNGNEFTSVLELDDANMDHVVLINGVSKAY
SMTGWRIGYAAGPQTIMAKMGVVLGHAASNPAAVSQYAAIEAFSGDQSSVETMRQGFEARLNELYPLIERLPGFKMPAGK
PAGAFYLFPDITEALRLTGYADAPAFVTAVLLEAHVGLVPGEAFGMPGCLRLSYATDIDSLREAHRRLQKFMTEKIAEQA
K

Sequences:

>Translated_401_residues
MYMELSRKVMQVQPSATLKISATAKQMMADGVDVINLGIGEPDFQTPDNIKQAAIDSIQNGQASFYTPATGLPALKQAIS
QRIEADHHYHFDPNQIVVTDGAKMALFTLFQVILNPDDEVLLPVPYWVSYSEQVKLAGGVPVEVSTDEQLRFTTADLEAQ
RTPKTKALVLNSPQNPSGLVFSRAELTAIVNWAVEHDVLVIADEIYEKLLYNGNEFTSVLELDDANMDHVVLINGVSKAY
SMTGWRIGYAAGPQTIMAKMGVVLGHAASNPAAVSQYAAIEAFSGDQSSVETMRQGFEARLNELYPLIERLPGFKMPAGK
PAGAFYLFPDITEALRLTGYADAPAFVTAVLLEAHVGLVPGEAFGMPGCLRLSYATDIDSLREAHRRLQKFMTEKIAEQA
K
>Mature_401_residues
MYMELSRKVMQVQPSATLKISATAKQMMADGVDVINLGIGEPDFQTPDNIKQAAIDSIQNGQASFYTPATGLPALKQAIS
QRIEADHHYHFDPNQIVVTDGAKMALFTLFQVILNPDDEVLLPVPYWVSYSEQVKLAGGVPVEVSTDEQLRFTTADLEAQ
RTPKTKALVLNSPQNPSGLVFSRAELTAIVNWAVEHDVLVIADEIYEKLLYNGNEFTSVLELDDANMDHVVLINGVSKAY
SMTGWRIGYAAGPQTIMAKMGVVLGHAASNPAAVSQYAAIEAFSGDQSSVETMRQGFEARLNELYPLIERLPGFKMPAGK
PAGAFYLFPDITEALRLTGYADAPAFVTAVLLEAHVGLVPGEAFGMPGCLRLSYATDIDSLREAHRRLQKFMTEKIAEQA
K

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713254, Length=323, Percent_Identity=30.3405572755418, Blast_Score=151, Evalue=9e-37,
Organism=Homo sapiens, GI56713256, Length=323, Percent_Identity=30.3405572755418, Blast_Score=150, Evalue=1e-36,
Organism=Homo sapiens, GI95147551, Length=403, Percent_Identity=28.0397022332506, Blast_Score=149, Evalue=7e-36,
Organism=Homo sapiens, GI169881279, Length=403, Percent_Identity=28.0397022332506, Blast_Score=149, Evalue=7e-36,
Organism=Homo sapiens, GI169881281, Length=397, Percent_Identity=25.4408060453401, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI4507369, Length=413, Percent_Identity=24.2130750605327, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI4885351, Length=368, Percent_Identity=25.5434782608696, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI149944424, Length=404, Percent_Identity=23.019801980198, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI7705897, Length=330, Percent_Identity=22.4242424242424, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI33469970, Length=330, Percent_Identity=22.4242424242424, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI187936925, Length=328, Percent_Identity=24.6951219512195, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI14211921, Length=328, Percent_Identity=24.6951219512195, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI19263340, Length=376, Percent_Identity=25, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI215599424, Length=349, Percent_Identity=24.6418338108883, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI1788627, Length=413, Percent_Identity=29.7820823244552, Blast_Score=145, Evalue=4e-36,
Organism=Escherichia coli, GI1788722, Length=380, Percent_Identity=27.8947368421053, Blast_Score=131, Evalue=8e-32,
Organism=Escherichia coli, GI1786816, Length=258, Percent_Identity=31.0077519379845, Blast_Score=125, Evalue=6e-30,
Organism=Caenorhabditis elegans, GI71994472, Length=417, Percent_Identity=29.2565947242206, Blast_Score=145, Evalue=5e-35,
Organism=Caenorhabditis elegans, GI71994476, Length=417, Percent_Identity=29.2565947242206, Blast_Score=145, Evalue=5e-35,
Organism=Caenorhabditis elegans, GI17567663, Length=381, Percent_Identity=26.7716535433071, Blast_Score=122, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17567369, Length=269, Percent_Identity=30.4832713754647, Blast_Score=112, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI71981209, Length=382, Percent_Identity=23.8219895287958, Blast_Score=66, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6322401, Length=319, Percent_Identity=26.3322884012539, Blast_Score=115, Evalue=1e-26,
Organism=Saccharomyces cerevisiae, GI6323118, Length=356, Percent_Identity=26.685393258427, Blast_Score=85, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6320317, Length=348, Percent_Identity=23.8505747126437, Blast_Score=80, Evalue=7e-16,
Organism=Drosophila melanogaster, GI28573069, Length=244, Percent_Identity=31.9672131147541, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24646114, Length=244, Percent_Identity=31.9672131147541, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI28573067, Length=244, Percent_Identity=31.9672131147541, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI28573065, Length=244, Percent_Identity=31.9672131147541, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI18859735, Length=406, Percent_Identity=23.8916256157635, Blast_Score=99, Evalue=5e-21,
Organism=Drosophila melanogaster, GI24641770, Length=396, Percent_Identity=25.5050505050505, Blast_Score=82, Evalue=9e-16,
Organism=Drosophila melanogaster, GI24641760, Length=396, Percent_Identity=25.5050505050505, Blast_Score=82, Evalue=9e-16,
Organism=Drosophila melanogaster, GI24641768, Length=396, Percent_Identity=25.5050505050505, Blast_Score=82, Evalue=9e-16,
Organism=Drosophila melanogaster, GI24641766, Length=396, Percent_Identity=25.5050505050505, Blast_Score=82, Evalue=9e-16,
Organism=Drosophila melanogaster, GI24641764, Length=396, Percent_Identity=25.5050505050505, Blast_Score=82, Evalue=9e-16,
Organism=Drosophila melanogaster, GI45551451, Length=396, Percent_Identity=25.5050505050505, Blast_Score=81, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 43784; Mature: 43784

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYMELSRKVMQVQPSATLKISATAKQMMADGVDVINLGIGEPDFQTPDNIKQAAIDSIQN
CCHHHHHHHHHCCCCCEEEEEHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHHHHCC
GQASFYTPATGLPALKQAISQRIEADHHYHFDPNQIVVTDGAKMALFTLFQVILNPDDEV
CCCEEECCCCCCHHHHHHHHHHHCCCCCEECCCCEEEEECCCHHHHHHHHHHHHCCCCCE
LLPVPYWVSYSEQVKLAGGVPVEVSTDEQLRFTTADLEAQRTPKTKALVLNSPQNPSGLV
EEECCHHCCCCCCEEECCCCEEEECCCCCEEEEEECCCCCCCCCCEEEEEECCCCCCCEE
FSRAELTAIVNWAVEHDVLVIADEIYEKLLYNGNEFTSVLELDDANMDHVVLINGVSKAY
EEHHHHHHHHHHHHHCCEEEEHHHHHHHHHCCCCCCEEEEEECCCCCCEEEEEECCHHHH
SMTGWRIGYAAGPQTIMAKMGVVLGHAASNPAAVSQYAAIEAFSGDQSSVETMRQGFEAR
HCCCEEEEECCCHHHHHHHHHHHEECCCCCCHHHHHHHHHEECCCCHHHHHHHHHHHHHH
LNELYPLIERLPGFKMPAGKPAGAFYLFPDITEALRLTGYADAPAFVTAVLLEAHVGLVP
HHHHHHHHHHCCCCCCCCCCCCCEEEECCCHHHHHHHCCCCCCHHHHHHHHHHHHCCCCC
GEAFGMPGCLRLSYATDIDSLREAHRRLQKFMTEKIAEQAK
CHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MYMELSRKVMQVQPSATLKISATAKQMMADGVDVINLGIGEPDFQTPDNIKQAAIDSIQN
CCHHHHHHHHHCCCCCEEEEEHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHHHHCC
GQASFYTPATGLPALKQAISQRIEADHHYHFDPNQIVVTDGAKMALFTLFQVILNPDDEV
CCCEEECCCCCCHHHHHHHHHHHCCCCCEECCCCEEEEECCCHHHHHHHHHHHHCCCCCE
LLPVPYWVSYSEQVKLAGGVPVEVSTDEQLRFTTADLEAQRTPKTKALVLNSPQNPSGLV
EEECCHHCCCCCCEEECCCCEEEECCCCCEEEEEECCCCCCCCCCEEEEEECCCCCCCEE
FSRAELTAIVNWAVEHDVLVIADEIYEKLLYNGNEFTSVLELDDANMDHVVLINGVSKAY
EEHHHHHHHHHHHHHCCEEEEHHHHHHHHHCCCCCCEEEEEECCCCCCEEEEEECCHHHH
SMTGWRIGYAAGPQTIMAKMGVVLGHAASNPAAVSQYAAIEAFSGDQSSVETMRQGFEAR
HCCCEEEEECCCHHHHHHHHHHHEECCCCCCHHHHHHHHHEECCCCHHHHHHHHHHHHHH
LNELYPLIERLPGFKMPAGKPAGAFYLFPDITEALRLTGYADAPAFVTAVLLEAHVGLVP
HHHHHHHHHHCCCCCCCCCCCCCEEEECCCHHHHHHHCCCCCCHHHHHHHHHHHHCCCCC
GEAFGMPGCLRLSYATDIDSLREAHRRLQKFMTEKIAEQAK
CHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1990006; 2155199 [H]