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The map label for this gene is recG [H]

Identifier: 28378326

GI number: 28378326

Start: 1480673

End: 1482712

Strand: Direct

Name: recG [H]

Synonym: lp_1627

Alternate gene names: 28378326

Gene position: 1480673-1482712 (Clockwise)

Preceding gene: 28378325

Following gene: 28378327

Centisome position: 44.76

GC content: 48.73

Gene sequence:

>2040_bases
ATGGGACAACAGTTGAGTGACGCGGTTGCAACTTTAAGTGGTGTCGGCCCAGCCCGCCAAAAAGGTTTAGCGGAGCTTGG
GATTAATACGATTGCAGATCTATTGACCTATTATCCCTTTCGCTATGAAGATCTACAGGTCAAAGACGTCAATGAAATCG
CCGATCAAGAAAAGGTGACACTAAAGGGTACTGTGGCTTCTGAACCTGTGCTAGCACGGTTTGGCCGTAAGAAGAATCGC
CTGAATTTTCGCTTGTTAATCGACCATGACGTCTATATGGTGACTTTTTTTAATCAACCATACTTGATGAAACAGATTGA
GACTGGCCAAGATTTAGCCGTTTATGGCAAGTGGGACGCCACGCGCAGTAGCTTGACGGGAATGAAGATCATCAATCCCA
ATAATGCGGATTCAGCGTTTGGTTCGATTTATCCGGCCAGCAAGACGGTCAAGCAGGGGACGATTCAGAAGATGATCAAA
CAAGCATATGAGTTATATGCCCCAGTCATTACGGACATTGTGCCTGCTAACTTACGTGCTAAATACCGACTGTTACCGCG
GCGCCAAATGATTCATGATATGCACTTCCCAGCTAGTCAAGCCGATTCAACGGCCGCTCGACGCTCAGCGACCTACGAGG
AGTTCTTGTTGTTTCAAATGCAAATGCAAGTTCTGAAGCAAACGGACGCGACGACGAACGGTATTGCGATCGCTTATGAC
AATGACCGACTAAAGGCGTTTATTAAAACACTGCCATTTGAATTGACCCACGCCCAAAAACGTGTCGTCAATGAAATTTG
TTTGGATTTGAAGTCACCGAAGCATATGAATCGGTTGCTTCAAGGTGACGTGGGGTCCGGGAAAACGATTGTGGCTGCCA
TTGTCATGTATGCGGCGATTACCGCTGGTTATCAGGCCGCGTTGATGGCGCCAACCGAAATTTTGGCTGAACAACACGCA
AATAACTTGGCCCAGGTCTTTGCCGACACGGATGTCAACGTTGCGCTGTTAACGGGTGCGACCAAGCCAGCTGCCCGCAA
GACATTGTTAGCAGCGCTGGCTGCTGGTGAGATCAACTTATTGATTGGCACGCACGCCCTGATCCAGGACGGGGTGACTT
ATGCTAATTTGGGATTAGTTATTACCGATGAGCAACATCGCTTTGGGGTTAACCAACGGGCCGCCTTTCGTCAAAAAGGC
GGGCAACCTGATGCACTAGCCATGACGGCAACACCAATTCCAAGGACATTGGCGATTACGGCGTATGGTGAAATGGACGT
TTCTGAAATTGATGAATTACCGGCTGGTCGGCAACCGATTCAAACCACTTGGGTACGGAGCAACCAAGCTAATTCGGCGT
TAAGCTTTGTTCATCAACAGATTGACAATGGATCGCAAGCCTATGTGGTGACACCATTGATTGAGGAATCCGAGACGCTG
GATGTTAAAAACGCCGAGGCTCTGTCAGCTAATTTACAAGAGTATTTTGGGGCGAGTGTTAAAGTTGGACTGTTGCACGG
TCGAATGAAACCTGAGGAAAAAGACGCGGTCATGGCGGCTTTTAAGGCGGGAGACATTCAGTTACTTGTTTCCACGACCG
TGATTGAAGTGGGTGTTGACGTCAAGAATGCCACAATCATGATGATTTATGATGCTGACCGTTTTGGCTTGGCGCAACTA
CATCAATTACGCGGACGCGTCGGTCGTGGGACCAAGGCTTCATACTGTATTTTGGTGGCTGATCCCAAGAACCAGCAAGG
GATTGAGCGGATGCAGATCATGACGCAGACAACAAATGGTTTTGTTTTGGCACAAAAAGACTTAGAATTACGAGGAGCCG
GTGATGTGCTGGGTGTCAAGCAATCGGGAATGCCGGAATTTAAAGTGGGTGATCCGATTGCGGATTTGACCGTGCTACAA
GTTGCCCAGCAAGATGCCCACGCAATCGTGCAGCAACCGGATTGGCAAAGTCAACCGGATAATCGGGCACTAGCCGCCTA
TTTGAGCCAGAAGTTGGCTGCGGTGGGGACGCTCGATTAA

Upstream 100 bases:

>100_bases
TGTTTTTGTACGGACGGATACTTCCCGCGGGATTGAAACGTTTTTTTGGTATAATTAATATTGGTAAAGGCAATTATTTT
AGAAAGGGCGGTGGTCAGGC

Downstream 100 bases:

>100_bases
TAACCTAAATACAGTACTGTGATGAGAGGAATGGTGACACAATGATTAAAATTGCGATTGATGCCATGGGTGGCGATTAC
GCCCCTAACGCTGTGATCGA

Product: ATP-dependent DNA helicase RecG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 679; Mature: 678

Protein sequence:

>679_residues
MGQQLSDAVATLSGVGPARQKGLAELGINTIADLLTYYPFRYEDLQVKDVNEIADQEKVTLKGTVASEPVLARFGRKKNR
LNFRLLIDHDVYMVTFFNQPYLMKQIETGQDLAVYGKWDATRSSLTGMKIINPNNADSAFGSIYPASKTVKQGTIQKMIK
QAYELYAPVITDIVPANLRAKYRLLPRRQMIHDMHFPASQADSTAARRSATYEEFLLFQMQMQVLKQTDATTNGIAIAYD
NDRLKAFIKTLPFELTHAQKRVVNEICLDLKSPKHMNRLLQGDVGSGKTIVAAIVMYAAITAGYQAALMAPTEILAEQHA
NNLAQVFADTDVNVALLTGATKPAARKTLLAALAAGEINLLIGTHALIQDGVTYANLGLVITDEQHRFGVNQRAAFRQKG
GQPDALAMTATPIPRTLAITAYGEMDVSEIDELPAGRQPIQTTWVRSNQANSALSFVHQQIDNGSQAYVVTPLIEESETL
DVKNAEALSANLQEYFGASVKVGLLHGRMKPEEKDAVMAAFKAGDIQLLVSTTVIEVGVDVKNATIMMIYDADRFGLAQL
HQLRGRVGRGTKASYCILVADPKNQQGIERMQIMTQTTNGFVLAQKDLELRGAGDVLGVKQSGMPEFKVGDPIADLTVLQ
VAQQDAHAIVQQPDWQSQPDNRALAAYLSQKLAAVGTLD

Sequences:

>Translated_679_residues
MGQQLSDAVATLSGVGPARQKGLAELGINTIADLLTYYPFRYEDLQVKDVNEIADQEKVTLKGTVASEPVLARFGRKKNR
LNFRLLIDHDVYMVTFFNQPYLMKQIETGQDLAVYGKWDATRSSLTGMKIINPNNADSAFGSIYPASKTVKQGTIQKMIK
QAYELYAPVITDIVPANLRAKYRLLPRRQMIHDMHFPASQADSTAARRSATYEEFLLFQMQMQVLKQTDATTNGIAIAYD
NDRLKAFIKTLPFELTHAQKRVVNEICLDLKSPKHMNRLLQGDVGSGKTIVAAIVMYAAITAGYQAALMAPTEILAEQHA
NNLAQVFADTDVNVALLTGATKPAARKTLLAALAAGEINLLIGTHALIQDGVTYANLGLVITDEQHRFGVNQRAAFRQKG
GQPDALAMTATPIPRTLAITAYGEMDVSEIDELPAGRQPIQTTWVRSNQANSALSFVHQQIDNGSQAYVVTPLIEESETL
DVKNAEALSANLQEYFGASVKVGLLHGRMKPEEKDAVMAAFKAGDIQLLVSTTVIEVGVDVKNATIMMIYDADRFGLAQL
HQLRGRVGRGTKASYCILVADPKNQQGIERMQIMTQTTNGFVLAQKDLELRGAGDVLGVKQSGMPEFKVGDPIADLTVLQ
VAQQDAHAIVQQPDWQSQPDNRALAAYLSQKLAAVGTLD
>Mature_678_residues
GQQLSDAVATLSGVGPARQKGLAELGINTIADLLTYYPFRYEDLQVKDVNEIADQEKVTLKGTVASEPVLARFGRKKNRL
NFRLLIDHDVYMVTFFNQPYLMKQIETGQDLAVYGKWDATRSSLTGMKIINPNNADSAFGSIYPASKTVKQGTIQKMIKQ
AYELYAPVITDIVPANLRAKYRLLPRRQMIHDMHFPASQADSTAARRSATYEEFLLFQMQMQVLKQTDATTNGIAIAYDN
DRLKAFIKTLPFELTHAQKRVVNEICLDLKSPKHMNRLLQGDVGSGKTIVAAIVMYAAITAGYQAALMAPTEILAEQHAN
NLAQVFADTDVNVALLTGATKPAARKTLLAALAAGEINLLIGTHALIQDGVTYANLGLVITDEQHRFGVNQRAAFRQKGG
QPDALAMTATPIPRTLAITAYGEMDVSEIDELPAGRQPIQTTWVRSNQANSALSFVHQQIDNGSQAYVVTPLIEESETLD
VKNAEALSANLQEYFGASVKVGLLHGRMKPEEKDAVMAAFKAGDIQLLVSTTVIEVGVDVKNATIMMIYDADRFGLAQLH
QLRGRVGRGTKASYCILVADPKNQQGIERMQIMTQTTNGFVLAQKDLELRGAGDVLGVKQSGMPEFKVGDPIADLTVLQV
AQQDAHAIVQQPDWQSQPDNRALAAYLSQKLAAVGTLD

Specific function: Critical role in recombination and DNA repair. Help process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3' to 5' polarity. RecG unwind branched dup

COG id: COG1200

COG function: function code LK; RecG-like helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI2367254, Length=677, Percent_Identity=40.4726735598227, Blast_Score=432, Evalue=1e-122,
Organism=Escherichia coli, GI1787357, Length=400, Percent_Identity=37, Blast_Score=255, Evalue=7e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004609
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR016027 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 74260; Mature: 74129

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: PS00435 PEROXIDASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGQQLSDAVATLSGVGPARQKGLAELGINTIADLLTYYPFRYEDLQVKDVNEIADQEKVT
CCCHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHHHCCCCCCCEEECCHHHHCCCCCEE
LKGTVASEPVLARFGRKKNRLNFRLLIDHDVYMVTFFNQPYLMKQIETGQDLAVYGKWDA
EEECCCCCHHHHHHCCCCCCCEEEEEEECCEEEEEEECCCHHHHHHCCCCCEEEEECCCC
TRSSLTGMKIINPNNADSAFGSIYPASKTVKQGTIQKMIKQAYELYAPVITDIVPANLRA
CHHCCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
KYRLLPRRQMIHDMHFPASQADSTAARRSATYEEFLLFQMQMQVLKQTDATTNGIAIAYD
HHEECCHHHHHHHCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEC
NDRLKAFIKTLPFELTHAQKRVVNEICLDLKSPKHMNRLLQGDVGSGKTIVAAIVMYAAI
CHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHH
TAGYQAALMAPTEILAEQHANNLAQVFADTDVNVALLTGATKPAARKTLLAALAAGEINL
HCCCHHEECCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHCCCEEE
LIGTHALIQDGVTYANLGLVITDEQHRFGVNQRAAFRQKGGQPDALAMTATPIPRTLAIT
EEECHHHHHCCCEEEEEEEEEECCHHHCCCCHHHHHHHCCCCCCEEEEECCCCCCEEEEE
AYGEMDVSEIDELPAGRQPIQTTWVRSNQANSALSFVHQQIDNGSQAYVVTPLIEESETL
EECCCCHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCCCEEEEEEECCCCCCC
DVKNAEALSANLQEYFGASVKVGLLHGRMKPEEKDAVMAAFKAGDIQLLVSTTVIEVGVD
CCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHEECCCCEEEEEEEEEEEECCC
VKNATIMMIYDADRFGLAQLHQLRGRVGRGTKASYCILVADPKNQQGIERMQIMTQTTNG
CCCEEEEEEEECCCCCHHHHHHHHHHCCCCCCCEEEEEEECCCCCHHHHHHHHHEECCCC
FVLAQKDLELRGAGDVLGVKQSGMPEFKVGDPIADLTVLQVAQQDAHAIVQQPDWQSQPD
EEEEECCCEECCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCC
NRALAAYLSQKLAAVGTLD
CHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
GQQLSDAVATLSGVGPARQKGLAELGINTIADLLTYYPFRYEDLQVKDVNEIADQEKVT
CCHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHHHCCCCCCCEEECCHHHHCCCCCEE
LKGTVASEPVLARFGRKKNRLNFRLLIDHDVYMVTFFNQPYLMKQIETGQDLAVYGKWDA
EEECCCCCHHHHHHCCCCCCCEEEEEEECCEEEEEEECCCHHHHHHCCCCCEEEEECCCC
TRSSLTGMKIINPNNADSAFGSIYPASKTVKQGTIQKMIKQAYELYAPVITDIVPANLRA
CHHCCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
KYRLLPRRQMIHDMHFPASQADSTAARRSATYEEFLLFQMQMQVLKQTDATTNGIAIAYD
HHEECCHHHHHHHCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEC
NDRLKAFIKTLPFELTHAQKRVVNEICLDLKSPKHMNRLLQGDVGSGKTIVAAIVMYAAI
CHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHH
TAGYQAALMAPTEILAEQHANNLAQVFADTDVNVALLTGATKPAARKTLLAALAAGEINL
HCCCHHEECCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHCCCEEE
LIGTHALIQDGVTYANLGLVITDEQHRFGVNQRAAFRQKGGQPDALAMTATPIPRTLAIT
EEECHHHHHCCCEEEEEEEEEECCHHHCCCCHHHHHHHCCCCCCEEEEECCCCCCEEEEE
AYGEMDVSEIDELPAGRQPIQTTWVRSNQANSALSFVHQQIDNGSQAYVVTPLIEESETL
EECCCCHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCCCEEEEEEECCCCCCC
DVKNAEALSANLQEYFGASVKVGLLHGRMKPEEKDAVMAAFKAGDIQLLVSTTVIEVGVD
CCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHEECCCCEEEEEEEEEEEECCC
VKNATIMMIYDADRFGLAQLHQLRGRVGRGTKASYCILVADPKNQQGIERMQIMTQTTNG
CCCEEEEEEEECCCCCHHHHHHHHHHCCCCCCCEEEEEEECCCCCHHHHHHHHHEECCCC
FVLAQKDLELRGAGDVLGVKQSGMPEFKVGDPIADLTVLQVAQQDAHAIVQQPDWQSQPD
EEEEECCCEECCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCC
NRALAAYLSQKLAAVGTLD
CHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377 [H]