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The map label for this gene is udk

Identifier: 28378268

GI number: 28378268

Start: 1428060

End: 1428689

Strand: Direct

Name: udk

Synonym: lp_1562

Alternate gene names: 28378268

Gene position: 1428060-1428689 (Clockwise)

Preceding gene: 28378267

Following gene: 28378269

Centisome position: 43.17

GC content: 43.02

Gene sequence:

>630_bases
ATGACTGAAAATAAACATCGCCGACCAGTAGTCATCGGGGTAACTGGTGGTTCCGGTAGTGGTAAAACTACGGTCAGCAA
TGCAATTTACAACCAATTATCTGGTCAATCATTGTTGATCTTACAACAGGATTCCTATTACAATGATCAAAGTGAAATGA
CAATGGCTGAGCGCCATGCCGTTAATTACGACCACCCACTGGCTTTCGATACAGATTTGATGATTAAGCAAATCAAGCAG
TTGCTGGCCTATCAACCAATTGAAAAGCCGGTCTATGATTACGAGCAGTATACGCGTAGCGACAAGACCATTCATCAAGA
ACCGCGTGATGTGATCATTGTCGAAGGGGTATTGATCCTAGATGATCAGCGTTTACGCGACCTGATGGATATTAAGGTGT
TCGTCGATACCGACGATGATATTCGAATCATTCGGCGCATTCAGCGTGATATCAAAGAGCGGGGCCGGACACTAGACTCT
GTGATTGGTCAATATTTGGCGACGGTCAAACCAATGTATCATCAGTTTGTGGAACCAACGAAACGTTATGCCGATCTAAT
TGTGCCAGAAGGTGGCGAAAATGAAGTTGCCATTGATTTATTGACAACTAAAGTTCGTTCAATTTTATAA

Upstream 100 bases:

>100_bases
TGTCTATTATGCAAAGGATGCTGCGGGTCACGCGGCAAACATCAAGAAGGTTTCGAAGCACAACGAAGCCGCTGAAAAAT
AAGAATGAGGCGTAACTTAA

Downstream 100 bases:

>100_bases
AAAATAACGTCTTAACCAGCGCTATTTTAGATTTAAGAGTTTACTTTTAAAATCTGAAATGGTAGGCTGGTTTTTGATAA
CTATATTGCGTATTTGAGGA

Product: uridine kinase

Products: NA

Alternate protein names: Cytidine monophosphokinase; Uridine monophosphokinase

Number of amino acids: Translated: 209; Mature: 208

Protein sequence:

>209_residues
MTENKHRRPVVIGVTGGSGSGKTTVSNAIYNQLSGQSLLILQQDSYYNDQSEMTMAERHAVNYDHPLAFDTDLMIKQIKQ
LLAYQPIEKPVYDYEQYTRSDKTIHQEPRDVIIVEGVLILDDQRLRDLMDIKVFVDTDDDIRIIRRIQRDIKERGRTLDS
VIGQYLATVKPMYHQFVEPTKRYADLIVPEGGENEVAIDLLTTKVRSIL

Sequences:

>Translated_209_residues
MTENKHRRPVVIGVTGGSGSGKTTVSNAIYNQLSGQSLLILQQDSYYNDQSEMTMAERHAVNYDHPLAFDTDLMIKQIKQ
LLAYQPIEKPVYDYEQYTRSDKTIHQEPRDVIIVEGVLILDDQRLRDLMDIKVFVDTDDDIRIIRRIQRDIKERGRTLDS
VIGQYLATVKPMYHQFVEPTKRYADLIVPEGGENEVAIDLLTTKVRSIL
>Mature_208_residues
TENKHRRPVVIGVTGGSGSGKTTVSNAIYNQLSGQSLLILQQDSYYNDQSEMTMAERHAVNYDHPLAFDTDLMIKQIKQL
LAYQPIEKPVYDYEQYTRSDKTIHQEPRDVIIVEGVLILDDQRLRDLMDIKVFVDTDDDIRIIRRIQRDIKERGRTLDSV
IGQYLATVKPMYHQFVEPTKRYADLIVPEGGENEVAIDLLTTKVRSIL

Specific function: Pyrimidine salvage pathway. [C]

COG id: COG0572

COG function: function code F; Uridine kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uridine kinase family

Homologues:

Organism=Homo sapiens, GI18699734, Length=211, Percent_Identity=41.7061611374408, Blast_Score=179, Evalue=2e-45,
Organism=Homo sapiens, GI57863312, Length=214, Percent_Identity=42.0560747663551, Blast_Score=171, Evalue=6e-43,
Organism=Homo sapiens, GI301129207, Length=210, Percent_Identity=41.9047619047619, Blast_Score=171, Evalue=6e-43,
Organism=Homo sapiens, GI13899253, Length=214, Percent_Identity=40.1869158878505, Blast_Score=169, Evalue=1e-42,
Organism=Homo sapiens, GI209863022, Length=151, Percent_Identity=38.4105960264901, Blast_Score=112, Evalue=3e-25,
Organism=Escherichia coli, GI87082034, Length=209, Percent_Identity=46.4114832535885, Blast_Score=208, Evalue=2e-55,
Organism=Caenorhabditis elegans, GI17539894, Length=205, Percent_Identity=43.4146341463415, Blast_Score=177, Evalue=2e-45,
Organism=Caenorhabditis elegans, GI17539892, Length=205, Percent_Identity=43.4146341463415, Blast_Score=177, Evalue=3e-45,
Organism=Caenorhabditis elegans, GI71981181, Length=210, Percent_Identity=33.8095238095238, Blast_Score=130, Evalue=4e-31,
Organism=Saccharomyces cerevisiae, GI6324339, Length=191, Percent_Identity=35.0785340314136, Blast_Score=117, Evalue=1e-27,
Organism=Saccharomyces cerevisiae, GI6320223, Length=114, Percent_Identity=33.3333333333333, Blast_Score=71, Evalue=2e-13,
Organism=Drosophila melanogaster, GI221458995, Length=214, Percent_Identity=40.1869158878505, Blast_Score=172, Evalue=2e-43,
Organism=Drosophila melanogaster, GI24649624, Length=214, Percent_Identity=40.1869158878505, Blast_Score=170, Evalue=6e-43,
Organism=Drosophila melanogaster, GI28573516, Length=203, Percent_Identity=41.3793103448276, Blast_Score=163, Evalue=6e-41,
Organism=Drosophila melanogaster, GI28573514, Length=203, Percent_Identity=41.3793103448276, Blast_Score=163, Evalue=6e-41,
Organism=Drosophila melanogaster, GI28573512, Length=203, Percent_Identity=41.3793103448276, Blast_Score=163, Evalue=6e-41,
Organism=Drosophila melanogaster, GI45550449, Length=203, Percent_Identity=41.3793103448276, Blast_Score=163, Evalue=6e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): URK_LACPL (Q88WR0)

Other databases:

- EMBL:   AL935256
- RefSeq:   NP_785160.1
- ProteinModelPortal:   Q88WR0
- GeneID:   1064138
- GenomeReviews:   AL935263_GR
- KEGG:   lpl:lp_1562
- NMPDR:   fig|220668.1.peg.1294
- HOGENOM:   HBG527126
- OMA:   NQFVEPT
- ProtClustDB:   PRK05480
- BioCyc:   LPLA220668:LP_1562-MONOMER
- BRENDA:   2.7.1.48
- GO:   GO:0005737
- HAMAP:   MF_00551
- InterPro:   IPR006083
- InterPro:   IPR000764
- PANTHER:   PTHR10285:SF6
- PRINTS:   PR00988
- TIGRFAMs:   TIGR00235

Pfam domain/function: PF00485 PRK

EC number: =2.7.1.48

Molecular weight: Translated: 24055; Mature: 23924

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTENKHRRPVVIGVTGGSGSGKTTVSNAIYNQLSGQSLLILQQDSYYNDQSEMTMAERHA
CCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHC
VNYDHPLAFDTDLMIKQIKQLLAYQPIEKPVYDYEQYTRSDKTIHQEPRDVIIVEGVLIL
CCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCHHHCCCCCEEEECCEEEE
DDQRLRDLMDIKVFVDTDDDIRIIRRIQRDIKERGRTLDSVIGQYLATVKPMYHQFVEPT
CCHHHHHHHHEEEEEECCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
KRYADLIVPEGGENEVAIDLLTTKVRSIL
HHHHHEECCCCCCCCEEHHHHHHHHHHHC
>Mature Secondary Structure 
TENKHRRPVVIGVTGGSGSGKTTVSNAIYNQLSGQSLLILQQDSYYNDQSEMTMAERHA
CCCCCCCCEEEEEECCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHC
VNYDHPLAFDTDLMIKQIKQLLAYQPIEKPVYDYEQYTRSDKTIHQEPRDVIIVEGVLIL
CCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCHHHCCCCCEEEECCEEEE
DDQRLRDLMDIKVFVDTDDDIRIIRRIQRDIKERGRTLDSVIGQYLATVKPMYHQFVEPT
CCHHHHHHHHEEEEEECCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
KRYADLIVPEGGENEVAIDLLTTKVRSIL
HHHHHEECCCCCCCCEEHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12566566