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The map label for this gene is nadD

Identifier: 28378242

GI number: 28378242

Start: 1398997

End: 1399632

Strand: Direct

Name: nadD

Synonym: lp_1530

Alternate gene names: 28378242

Gene position: 1398997-1399632 (Clockwise)

Preceding gene: 28378241

Following gene: 28378243

Centisome position: 42.29

GC content: 47.17

Gene sequence:

>636_bases
GTGCAGACGGTTAATCAAACAGCGACAAAAGTTCTGACGGAAACGGTGACGGCAATTCCGCATCGCCGTGTTGGTATTTT
AGGTGGCACGTTTAACCCACCGCATTTGGGACATTTGATCATGGCCCAGCAAGTTGGTGATCAACTGGGTTTGGATGAAG
TTCGCTTTATGCCGGACGCTCAACCACCGCATGTCGACGAAAAGAAGACGATTGCGGTGGAAGATCGTGCGAATATGGTC
CAAGAAGCCATTGTTGATAATCCACTATTTCGGTTGGAGACGGCGGAAATCGAGCGGGGTGGCAAAAGCTATACTTACGA
AACGATGAAGTTTTTGAAAGCTAAGCATCCGGACACGCAGTACTATTTCATCATTGGCGGCGACATGGTCGATTATTTGC
ATACTTGGTATCACATTGACGAGCTAGTTAAATTAGTCACCTTTGTTGGTATCAAACGAACCGGGTACCCAACGACGAGT
CAATATCCGGTTATTTGGGTCGACGCACCGTTGATCGATATTAGTTCCACTCAGATTCGTCAAAAAATCAGCCACGGGCA
TTCGGTCCGTTATCTGGTTCCGGAAGCCGTGGCCGCTTATATTAAGGAGCATCATTTGTATGAGCAAAACGATTGA

Upstream 100 bases:

>100_bases
TCAAACAATTGGCCGGGTGTTAGTCTTATACTTGCCAGCTAGTCATGAAGAAGACCAGCACTATTCATTGGAAGTTGCTA
AGTTATAGGAGGAATGACGG

Downstream 100 bases:

>100_bases
GTATACTGAAGCGATTGTTCCATATCGTCACGAGGAGCTAATGGCAAAAGTTGCCGCCCAGTTGACTGACAAACGCTATC
AACACTGCTTACGGGTCGAG

Product: nicotinic acid mononucleotide adenylyltransferase

Products: NA

Alternate protein names: Deamido-NAD(+) diphosphorylase; Deamido-NAD(+) pyrophosphorylase; Nicotinate mononucleotide adenylyltransferase; NaMN adenylyltransferase

Number of amino acids: Translated: 211; Mature: 211

Protein sequence:

>211_residues
MQTVNQTATKVLTETVTAIPHRRVGILGGTFNPPHLGHLIMAQQVGDQLGLDEVRFMPDAQPPHVDEKKTIAVEDRANMV
QEAIVDNPLFRLETAEIERGGKSYTYETMKFLKAKHPDTQYYFIIGGDMVDYLHTWYHIDELVKLVTFVGIKRTGYPTTS
QYPVIWVDAPLIDISSTQIRQKISHGHSVRYLVPEAVAAYIKEHHLYEQND

Sequences:

>Translated_211_residues
MQTVNQTATKVLTETVTAIPHRRVGILGGTFNPPHLGHLIMAQQVGDQLGLDEVRFMPDAQPPHVDEKKTIAVEDRANMV
QEAIVDNPLFRLETAEIERGGKSYTYETMKFLKAKHPDTQYYFIIGGDMVDYLHTWYHIDELVKLVTFVGIKRTGYPTTS
QYPVIWVDAPLIDISSTQIRQKISHGHSVRYLVPEAVAAYIKEHHLYEQND
>Mature_211_residues
MQTVNQTATKVLTETVTAIPHRRVGILGGTFNPPHLGHLIMAQQVGDQLGLDEVRFMPDAQPPHVDEKKTIAVEDRANMV
QEAIVDNPLFRLETAEIERGGKSYTYETMKFLKAKHPDTQYYFIIGGDMVDYLHTWYHIDELVKLVTFVGIKRTGYPTTS
QYPVIWVDAPLIDISSTQIRQKISHGHSVRYLVPEAVAAYIKEHHLYEQND

Specific function: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)

COG id: COG1057

COG function: function code H; Nicotinic acid mononucleotide adenylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nadD family

Homologues:

Organism=Escherichia coli, GI1786858, Length=208, Percent_Identity=30.7692307692308, Blast_Score=111, Evalue=3e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NADD_LACPL (Q88WT5)

Other databases:

- EMBL:   AL935256
- RefSeq:   NP_785134.1
- ProteinModelPortal:   Q88WT5
- SMR:   Q88WT5
- GeneID:   1064140
- GenomeReviews:   AL935263_GR
- KEGG:   lpl:lp_1530
- NMPDR:   fig|220668.1.peg.1268
- HOGENOM:   HBG739448
- OMA:   LLGWDAF
- ProtClustDB:   PRK00071
- BioCyc:   LPLA220668:LP_1530-MONOMER
- BRENDA:   2.7.7.18
- HAMAP:   MF_00244
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR005248
- InterPro:   IPR019450
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR12039
- TIGRFAMs:   TIGR00125
- TIGRFAMs:   TIGR00482

Pfam domain/function: PF01467 CTP_transf_2; PF10362 DUF2432

EC number: =2.7.7.18

Molecular weight: Translated: 24028; Mature: 24028

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTVNQTATKVLTETVTAIPHRRVGILGGTFNPPHLGHLIMAQQVGDQLGLDEVRFMPDA
CCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHHHHCCCCHHHCCCCC
QPPHVDEKKTIAVEDRANMVQEAIVDNPLFRLETAEIERGGKSYTYETMKFLKAKHPDTQ
CCCCCCCCCEEEEHHHHHHHHHHHHCCCCCEEEHHHHHCCCCCHHHHHHHHHHHCCCCCE
YYFIIGGDMVDYLHTWYHIDELVKLVTFVGIKRTGYPTTSQYPVIWVDAPLIDISSTQIR
EEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCEEECCHHHHH
QKISHGHSVRYLVPEAVAAYIKEHHLYEQND
HHHHCCCEEEEECHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MQTVNQTATKVLTETVTAIPHRRVGILGGTFNPPHLGHLIMAQQVGDQLGLDEVRFMPDA
CCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHHHHCCCCHHHCCCCC
QPPHVDEKKTIAVEDRANMVQEAIVDNPLFRLETAEIERGGKSYTYETMKFLKAKHPDTQ
CCCCCCCCCEEEEHHHHHHHHHHHHCCCCCEEEHHHHHCCCCCHHHHHHHHHHHCCCCCE
YYFIIGGDMVDYLHTWYHIDELVKLVTFVGIKRTGYPTTSQYPVIWVDAPLIDISSTQIR
EEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCEEECCHHHHH
QKISHGHSVRYLVPEAVAAYIKEHHLYEQND
HHHHCCCEEEEECHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12566566