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The map label for this gene is nrnA [H]

Identifier: 28378117

GI number: 28378117

Start: 1264324

End: 1265301

Strand: Direct

Name: nrnA [H]

Synonym: lp_1380

Alternate gene names: 28378117

Gene position: 1264324-1265301 (Clockwise)

Preceding gene: 28378116

Following gene: 28378118

Centisome position: 38.22

GC content: 49.69

Gene sequence:

>978_bases
ATGTCAGTTTGGTTACTGCAAATGAAAACTAATGCAATCATTACTGACATCACAAAATCGATTGTGAAAATGGACCGAAT
CTTGGTCTATCGTCATACGAATCCGGATCCCGATGCAATCGGGGCACAATTTGGACTAGTCGCCTTGCTCAAAGCGGCTT
ACCCGGAGAAACTTGTTGTGGCGATGGCCCCAGTTCCGGGCCATTTGGCGTGGATCGATACAACCGATGAGCAGTTAGTG
ACCCCCCAAGCAACGGACTTAGTCATTGCCGTAGATTGTGCTAACCATGAGCGCCTAGCTGGGGAGTTGCCAACAGGTGC
CTTTGTGATTAAAATCGACCATCACCCGAATCACGATCCCTATGGGCAACTGAACTGGGTCGATGAAACTTATAGCAGTT
GCTCGGAGATGATTTATGAGTTGGCGCAAGCGGGGTGTTTTACAGTGACGGCGGCCGTTGCAACCAAGCTATATGCCGGA
ATTATCGGCGATACGGTGCGCTTTTCAACTCCCGAGACGTCCACTCGAACTCTGAAGATTGCTAGTGCACTCGCGGCAAC
GGACATTGATATTGCCACTATTAGTCACCACGAAATGGACTTAACGCCAGCACTCAGCAAGTTGTATGGGTACGTCCTGA
GTGAACAAACTATTGAGCCAAGTGGTCTGGCACACGTTGTCTTACCACAACGGATATTTAGTGACTTGAGTCTGGAATAT
GGCGATGAGGATGCGCTTGTCCCGTTGCCCGGTAACCTGACGACGGTCAAAGTTTGGTTGTTCTTCATTGAAACCCCACA
GGGGCAATACCGCGTACATTTTCGGTCGAAAGCAATCAATGTCAATGCGGTCGCAAAAGCGTTCAATGGCGGCGGTCATC
CGTTAGCAAGTGGGGCATTTGTTCCTGACCTAGCGACAGTTGGACAAGTCATTGAGCAAATGCAGGCGCAAGTATTGGCT
GCGACGGCAGTAGATTAA

Upstream 100 bases:

>100_bases
TACGAAGCACCTATCGATCCTGAGATTACGATTGACACGTCCAAACAACCACTGACCGCTTCCGTCCAACAAGTATTGAA
TTACTTGGCGGAACACCATT

Downstream 100 bases:

>100_bases
GTATAATAAATTTAATATAAACTGAACTGATTCGGTTCGGCATGGCAATTGTTAGTCATTCTGTGTCGGTCACGTGGGTT
GCCACGGGAAGGTTAGACCG

Product: exopolyphosphatase-related protein (putative)

Products: NA

Alternate protein names: 3'(2'),5'-bisphosphate nucleotidase; 3'-phosphoadenosine 5'-phosphate phosphatase; PAP phosphatase; nanoRNAse [H]

Number of amino acids: Translated: 325; Mature: 324

Protein sequence:

>325_residues
MSVWLLQMKTNAIITDITKSIVKMDRILVYRHTNPDPDAIGAQFGLVALLKAAYPEKLVVAMAPVPGHLAWIDTTDEQLV
TPQATDLVIAVDCANHERLAGELPTGAFVIKIDHHPNHDPYGQLNWVDETYSSCSEMIYELAQAGCFTVTAAVATKLYAG
IIGDTVRFSTPETSTRTLKIASALAATDIDIATISHHEMDLTPALSKLYGYVLSEQTIEPSGLAHVVLPQRIFSDLSLEY
GDEDALVPLPGNLTTVKVWLFFIETPQGQYRVHFRSKAINVNAVAKAFNGGGHPLASGAFVPDLATVGQVIEQMQAQVLA
ATAVD

Sequences:

>Translated_325_residues
MSVWLLQMKTNAIITDITKSIVKMDRILVYRHTNPDPDAIGAQFGLVALLKAAYPEKLVVAMAPVPGHLAWIDTTDEQLV
TPQATDLVIAVDCANHERLAGELPTGAFVIKIDHHPNHDPYGQLNWVDETYSSCSEMIYELAQAGCFTVTAAVATKLYAG
IIGDTVRFSTPETSTRTLKIASALAATDIDIATISHHEMDLTPALSKLYGYVLSEQTIEPSGLAHVVLPQRIFSDLSLEY
GDEDALVPLPGNLTTVKVWLFFIETPQGQYRVHFRSKAINVNAVAKAFNGGGHPLASGAFVPDLATVGQVIEQMQAQVLA
ATAVD
>Mature_324_residues
SVWLLQMKTNAIITDITKSIVKMDRILVYRHTNPDPDAIGAQFGLVALLKAAYPEKLVVAMAPVPGHLAWIDTTDEQLVT
PQATDLVIAVDCANHERLAGELPTGAFVIKIDHHPNHDPYGQLNWVDETYSSCSEMIYELAQAGCFTVTAAVATKLYAGI
IGDTVRFSTPETSTRTLKIASALAATDIDIATISHHEMDLTPALSKLYGYVLSEQTIEPSGLAHVVLPQRIFSDLSLEYG
DEDALVPLPGNLTTVKVWLFFIETPQGQYRVHFRSKAINVNAVAKAFNGGGHPLASGAFVPDLATVGQVIEQMQAQVLAA
TAVD

Specific function: Bifunctional enzyme which has both oligoribonuclease and pAp-phosphatase activities. Degrades RNA oligonucleotides with a length of 5 nucleotides and shorter. Converts 3'(2')- phosphoadenosine 5'-phosphate (PAP) to AMP [H]

COG id: COG0618

COG function: function code R; Exopolyphosphatase-related proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003156
- InterPro:   IPR001667 [H]

Pfam domain/function: PF01368 DHH; PF02272 DHHA1 [H]

EC number: =3.1.3.7 [H]

Molecular weight: Translated: 35163; Mature: 35031

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVWLLQMKTNAIITDITKSIVKMDRILVYRHTNPDPDAIGAQFGLVALLKAAYPEKLVV
CCEEEEEEECCHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHHHHHHHCCCCEEEE
AMAPVPGHLAWIDTTDEQLVTPQATDLVIAVDCANHERLAGELPTGAFVIKIDHHPNHDP
EECCCCCCEEEEECCCCCEECCCCCCEEEEEECCCCCHHCCCCCCCEEEEEECCCCCCCC
YGQLNWVDETYSSCSEMIYELAQAGCFTVTAAVATKLYAGIIGDTVRFSTPETSTRTLKI
CCCEECHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCEEEH
ASALAATDIDIATISHHEMDLTPALSKLYGYVLSEQTIEPSGLAHVVLPQRIFSDLSLEY
HHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEHHHHHHHCCCCC
GDEDALVPLPGNLTTVKVWLFFIETPQGQYRVHFRSKAINVNAVAKAFNGGGHPLASGAF
CCCCCEEECCCCCEEEEEEEEEEECCCCCEEEEEEECEEEHHHHHHHHCCCCCCCCCCCC
VPDLATVGQVIEQMQAQVLAATAVD
CCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SVWLLQMKTNAIITDITKSIVKMDRILVYRHTNPDPDAIGAQFGLVALLKAAYPEKLVV
CEEEEEEECCHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHHHHHHHCCCCEEEE
AMAPVPGHLAWIDTTDEQLVTPQATDLVIAVDCANHERLAGELPTGAFVIKIDHHPNHDP
EECCCCCCEEEEECCCCCEECCCCCCEEEEEECCCCCHHCCCCCCCEEEEEECCCCCCCC
YGQLNWVDETYSSCSEMIYELAQAGCFTVTAAVATKLYAGIIGDTVRFSTPETSTRTLKI
CCCEECHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCEEEH
ASALAATDIDIATISHHEMDLTPALSKLYGYVLSEQTIEPSGLAHVVLPQRIFSDLSLEY
HHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEHHHHHHHCCCCC
GDEDALVPLPGNLTTVKVWLFFIETPQGQYRVHFRSKAINVNAVAKAFNGGGHPLASGAF
CCCCCEEECCCCCEEEEEEEEEEECCCCCEEEEEEECEEEHHHHHHHHCCCCCCCCCCCC
VPDLATVGQVIEQMQAQVLAATAVD
CCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9387221; 9384377 [H]