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The map label for this gene is asd1 [H]

Identifier: 28378089

GI number: 28378089

Start: 1236566

End: 1237648

Strand: Direct

Name: asd1 [H]

Synonym: lp_1346

Alternate gene names: 28378089

Gene position: 1236566-1237648 (Clockwise)

Preceding gene: 28378087

Following gene: 28378090

Centisome position: 37.38

GC content: 42.84

Gene sequence:

>1083_bases
ATGTCTAAAAGTTATGTTGTTGCAATTTTAGGTGCTACTGGCGCAGTGGGCACGCGGATGGTTGATCAGCTCGCTGAATC
TGATATTCAGGTATCCAAGTTGAAGTTGCTGGCTTCTGCACGCTCGGTTGGCAAAAAAATGGGCTTTCGAGGTCAAAGTT
TGACTGTGCAGGCCGCCACGCCTGATTCCTTTAACGGTGTTGATATTGTGTTGGCATCCGCAGGGGGGCAGGTTTCTGCT
AGATTATTACCCGAAGCAGTTAAAAGAGGTGCTGTTTGCATTGATAATACATCTTATTTTCGGATGAATGACCACGTCCC
ACTGATCGTACCAGAAGTAAATGTCGACCAAATTCAGAATCATCATGGCATAATTGCAAATCCAAATTGTTCGACCATTG
AAATGGTCGTTGCCTTGAATCCAGTACGTGTAAAGTATGGATTGAAACAGATTATTGTCTCAACTTATCAATCAGCTGGT
GGTGCAGGACAAGCGGGGATTAAAGAATTGTACCGTGAGGCTAAAGCGTATTTAAACAATGAGCCCGTAAAAAGTGAAAT
TTTACCTGTCAAAGGTGGTAAACGGCATTATCCCATTGCTTTTAATTTATTACCGCAAATCGATGTCTTTGAAAATAATG
ATTATACTCATGAAGAACAAAAAATGATTCATGAGACTAAGAAGATAATGTGTGGAGATAAGAATAGTACCGAGTTAAAA
ATCACGGCAACTTGTGTCCGTGTCCCAATCCCAATTGCTCACGGTGAAACAGTTTATTTTACAACTGAAATGACGCCATC
ATCAGATGATATTAGGAGAACCTTGACGAAGGCGCCTGGTGTTGTTGTGCAAGATGATCCACAACATCAGGTTTACCCAC
AGCCTGTAAATGTGATTGGGAGCGATGCGACCTTTGTGGGCCGAGTTCGCTCAGATATGGAAAATCAGCGAGCTTACCAT
ATGTGGGTGGTTGCGGATAATCTCATAAAAGGGGCTGCTGGCAACGCTGTTCAGATTGCGGAAGAACTAATTAACCAAGG
TGCTGTTCACGAGTCGAAAGCCTCAGCGGTATTATTTGAATAG

Upstream 100 bases:

>100_bases
GCATAGGAAGAAAAAAGTGCGTACTTTACATTTTCGCTCTTGAGTTTTATTCTAACCCGTGAAACAAAAAATAATCTCGA
AAATTGGTGGCGTTAATATT

Downstream 100 bases:

>100_bases
TTGGTTCGGTAAATTAGTTACAATTAAATACTGATAAACACATTTTAATGAAAGCCTTCTTGGAGAATTATTGAGGAGGC
TTTTAAAAAAGATTCTAGGG

Product: aspartate-semialdehyde dehydrogenase

Products: NA

Alternate protein names: ASA dehydrogenase; ASADH [H]

Number of amino acids: Translated: 360; Mature: 359

Protein sequence:

>360_residues
MSKSYVVAILGATGAVGTRMVDQLAESDIQVSKLKLLASARSVGKKMGFRGQSLTVQAATPDSFNGVDIVLASAGGQVSA
RLLPEAVKRGAVCIDNTSYFRMNDHVPLIVPEVNVDQIQNHHGIIANPNCSTIEMVVALNPVRVKYGLKQIIVSTYQSAG
GAGQAGIKELYREAKAYLNNEPVKSEILPVKGGKRHYPIAFNLLPQIDVFENNDYTHEEQKMIHETKKIMCGDKNSTELK
ITATCVRVPIPIAHGETVYFTTEMTPSSDDIRRTLTKAPGVVVQDDPQHQVYPQPVNVIGSDATFVGRVRSDMENQRAYH
MWVVADNLIKGAAGNAVQIAEELINQGAVHESKASAVLFE

Sequences:

>Translated_360_residues
MSKSYVVAILGATGAVGTRMVDQLAESDIQVSKLKLLASARSVGKKMGFRGQSLTVQAATPDSFNGVDIVLASAGGQVSA
RLLPEAVKRGAVCIDNTSYFRMNDHVPLIVPEVNVDQIQNHHGIIANPNCSTIEMVVALNPVRVKYGLKQIIVSTYQSAG
GAGQAGIKELYREAKAYLNNEPVKSEILPVKGGKRHYPIAFNLLPQIDVFENNDYTHEEQKMIHETKKIMCGDKNSTELK
ITATCVRVPIPIAHGETVYFTTEMTPSSDDIRRTLTKAPGVVVQDDPQHQVYPQPVNVIGSDATFVGRVRSDMENQRAYH
MWVVADNLIKGAAGNAVQIAEELINQGAVHESKASAVLFE
>Mature_359_residues
SKSYVVAILGATGAVGTRMVDQLAESDIQVSKLKLLASARSVGKKMGFRGQSLTVQAATPDSFNGVDIVLASAGGQVSAR
LLPEAVKRGAVCIDNTSYFRMNDHVPLIVPEVNVDQIQNHHGIIANPNCSTIEMVVALNPVRVKYGLKQIIVSTYQSAGG
AGQAGIKELYREAKAYLNNEPVKSEILPVKGGKRHYPIAFNLLPQIDVFENNDYTHEEQKMIHETKKIMCGDKNSTELKI
TATCVRVPIPIAHGETVYFTTEMTPSSDDIRRTLTKAPGVVVQDDPQHQVYPQPVNVIGSDATFVGRVRSDMENQRAYHM
WVVADNLIKGAAGNAVQIAEELINQGAVHESKASAVLFE

Specific function: Unknown

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1788658, Length=349, Percent_Identity=29.7994269340974, Blast_Score=153, Evalue=1e-38,
Organism=Escherichia coli, GI1789841, Length=360, Percent_Identity=25.2777777777778, Blast_Score=79, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6320362, Length=404, Percent_Identity=27.4752475247525, Blast_Score=89, Evalue=8e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000319
- InterPro:   IPR012080
- InterPro:   IPR005986
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.11 [H]

Molecular weight: Translated: 39120; Mature: 38989

Theoretical pI: Translated: 7.32; Mature: 7.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKSYVVAILGATGAVGTRMVDQLAESDIQVSKLKLLASARSVGKKMGFRGQSLTVQAAT
CCCCEEEEEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECC
PDSFNGVDIVLASAGGQVSARLLPEAVKRGAVCIDNTSYFRMNDHVPLIVPEVNVDQIQN
CCCCCCEEEEEECCCCCCHHHHHHHHHHCCCEEEECCEEEEECCCCEEEEECCCHHHHHC
HHGIIANPNCSTIEMVVALNPVRVKYGLKQIIVSTYQSAGGAGQAGIKELYREAKAYLNN
CCCEEECCCCCEEEEEEEECCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCC
EPVKSEILPVKGGKRHYPIAFNLLPQIDVFENNDYTHEEQKMIHETKKIMCGDKNSTELK
CCCHHCEEECCCCCEECCEEEECCCCEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCEEE
ITATCVRVPIPIAHGETVYFTTEMTPSSDDIRRTLTKAPGVVVQDDPQHQVYPQPVNVIG
EEEEEEEEEEEECCCCEEEEEEECCCCHHHHHHHHHHCCCEEEECCCCCCCCCCCCCEEC
SDATFVGRVRSDMENQRAYHMWVVADNLIKGAAGNAVQIAEELINQGAVHESKASAVLFE
CCCHHHHHHHHHHHCCCEEEEEEEECCHHCCCCCCHHHHHHHHHHCCCCCCCCCCEEECC
>Mature Secondary Structure 
SKSYVVAILGATGAVGTRMVDQLAESDIQVSKLKLLASARSVGKKMGFRGQSLTVQAAT
CCCEEEEEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECC
PDSFNGVDIVLASAGGQVSARLLPEAVKRGAVCIDNTSYFRMNDHVPLIVPEVNVDQIQN
CCCCCCEEEEEECCCCCCHHHHHHHHHHCCCEEEECCEEEEECCCCEEEEECCCHHHHHC
HHGIIANPNCSTIEMVVALNPVRVKYGLKQIIVSTYQSAGGAGQAGIKELYREAKAYLNN
CCCEEECCCCCEEEEEEEECCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCC
EPVKSEILPVKGGKRHYPIAFNLLPQIDVFENNDYTHEEQKMIHETKKIMCGDKNSTELK
CCCHHCEEECCCCCEECCEEEECCCCEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCEEE
ITATCVRVPIPIAHGETVYFTTEMTPSSDDIRRTLTKAPGVVVQDDPQHQVYPQPVNVIG
EEEEEEEEEEEECCCCEEEEEEECCCCHHHHHHHHHHCCCEEEECCCCCCCCCCCCCEEC
SDATFVGRVRSDMENQRAYHMWVVADNLIKGAAGNAVQIAEELINQGAVHESKASAVLFE
CCCHHHHHHHHHHHCCCEEEEEEEECCHHCCCCCCHHHHHHHHHHCCCCCCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8098035; 9384377; 8345520 [H]