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The map label for this gene is ltaS1 [H]

Identifier: 28378043

GI number: 28378043

Start: 1166254

End: 1168359

Strand: Direct

Name: ltaS1 [H]

Synonym: lp_1283

Alternate gene names: 28378043

Gene position: 1166254-1168359 (Clockwise)

Preceding gene: 28378042

Following gene: 28378048

Centisome position: 35.25

GC content: 43.73

Gene sequence:

>2106_bases
ATGCCTAAATTTATAAAAAACACGGTTGGGAAGGTCAACACAACGTTGGGCTTTTACCTCCTAACCGTGGTCTTATTTTG
GCTAAAGACATATATCGCTTATAAGAGCGAGTTTACTTTAGGGGTTAAGGGACCCGTTCAGGAATTTATCTTGTTCTTGA
ATCCATTTCCGACAGCGATCGTGCTGCTCGGTATTGCCCTATATTTCCGTGGTCGCTTAAAGTATTGGATTATGATGATC
ATTGACGCCCTACAGACGACGTGGTTATTTGCCAATATCTTGTATTACCGGGAATTCTCTGATTTCATGTCGGCGGGGGT
AATTAAGAGTTCCGGTGCTGCTAGTAATAACCTCGGAAAGAGTTTGGGACAGATCATTCATGGAACCGACTTCCTAGTTT
ATGCAGATGTCGTGTTGCTGATTCTGTTATTAGCCTTCAAGGTCATTCGGATCGATCCACGGCCTTTCAAAATTCGGTAT
GCGGCAACACTGACCATGATTGGGGTGGCGTTGTTTGCTGTTGACCTCGGCATGTCTGAACATGACCGTTCAGATTTATT
GACGCGGACTTTTGATAACAACTACATCGTTAAGTACTTGGGACTCAACACATATGCAGGGTATAGCTTCTATCAGACCG
AAAAGGAAAGTGCGACGCGCGCCCAAGCAAGTAGTAGTGATATGAAGAGTGTGCTAGCCTACCTCAAGAAAAACCAGGCT
GGCGAGAACGTCAAATACTTTGGTAAAGCGAAGGGCAAGAACGTCTTCGTGATTCATTTGGAAAGTTTCCAGCAATTTTT
AATTGATTATAAGGTCGATGGTAAGGAAGTTACCCCGAACCTGAACAAGTTCTATCATGATAAGAGTACTTTGAGTTTTG
ATAATTTCTACCATCAAGTGGCGCAAGGGAAGACCTCTGATGCTGAAATGATGATGGAAAACTCTTTGTTTGGTTTACCA
ACCGGGTCAGCGATGACGCAGTATGGGACGTCGAACACGTTCCAGGCAGCGCCAGCAATCCTGTCACAAAAGGGCTATAC
GACTGCGGCTTTCCACGGTGATGTGGCTAGTTTCTGGAATCGGGATAACGCGTATAAGTCGTGGGGGTATAACTACTTCT
TCTACTCTTCTTACTATAAAGAGAAGTCAGACTACAATATTGGTTATGGCTTGAAGGATAAAATCTTCTTCAAAGACTCT
GTTAAGTATTTGGAGCAATTACCACAACCGTTCTACGCAAAGCTGATTACGTTGACGAACCACTATCCATACGAATTGGA
TAAGAAGAACCAGTCGATCGATAAGACGACGACCGGGGATTCAACCGTTGATGGCTACGTTCAGACGGCCCATTATCTTG
ATCAAGCCTTTGCCGAATTCATTAGTTACTTGAAGAAGGCCGGCTTATATAAGAATAGTATGATTGTGCTTTATGGAGAT
CATTATGGGATTTCAAACAACCATAAGGCTGCCATTGCACAGTTATTGGGTAAAAAGTCGGTAACGAGTTTCGACTTGGC
TCAATTCCAGAAAGTACCATTTATGATTCATTCTGAAGGAATCAAGGGTGGTATTAACCACACGTATGGTGGTGAAATTG
ATGCGTTGCCAACGATTTTTGACCTGTTAGGGATCAAGAACAAGGGTTACATCCAGTTCGGAACGGACTTACTGTCGAAA
CAGCATAACCAGACAGTGGCTTTCCGGAACGGGGATTTTGTCTCACCGACATATACGAAGATCAGTGGGACAGTCTATGA
TTCGAAGACCGGTAAGAAGCTAACGGATATGACGACGAAGCAGAAGGATACCGTCAAACAGATGCAAAATCATGTGACGA
CGGAACTCTCACTCTCTGATCGGGTCATCCAGGGTGACTTACTACGGTTCTACACGCCTAAGGGCTTTAAGAAGGTCAAT
AAGTCGGACTATAGTTATAAGCTGACTAAGACCCTCAAATCATTGAAAGAGATCCAAGCTGAGAAGAAGACGAGTGTTCT
CTCGAAGCATAAGGGCAAATCAACGGAGAGTCTGTATAAGACGGATGCACCAGAACTGTCTAGCTCAAGTGACAGTAGTA
GTAGTTCAAGCAGTAGTTCTGATTAA

Upstream 100 bases:

>100_bases
TGTTGAAGAATTTTTGAAGAAATCTTCAAGATATTGCTAACTAGTACGCAACCGTTATAATATGGATTTGTTAATAGCAA
TAACGGAGGAAGAAATTACC

Downstream 100 bases:

>100_bases
TCGAACTCGTATCAACTAAGGGATAACGCTGACGGCGTTATCCCTTTTTGGTTGCGGAAATAAGCTGCCACTTGTTTTGA
CCACAGCGCGGTACACTATT

Product: alkaline phosphatase superfamily protein

Products: NA

Alternate protein names: LTA synthase 1; Polyglycerol phosphate synthase 1 [H]

Number of amino acids: Translated: 701; Mature: 700

Protein sequence:

>701_residues
MPKFIKNTVGKVNTTLGFYLLTVVLFWLKTYIAYKSEFTLGVKGPVQEFILFLNPFPTAIVLLGIALYFRGRLKYWIMMI
IDALQTTWLFANILYYREFSDFMSAGVIKSSGAASNNLGKSLGQIIHGTDFLVYADVVLLILLLAFKVIRIDPRPFKIRY
AATLTMIGVALFAVDLGMSEHDRSDLLTRTFDNNYIVKYLGLNTYAGYSFYQTEKESATRAQASSSDMKSVLAYLKKNQA
GENVKYFGKAKGKNVFVIHLESFQQFLIDYKVDGKEVTPNLNKFYHDKSTLSFDNFYHQVAQGKTSDAEMMMENSLFGLP
TGSAMTQYGTSNTFQAAPAILSQKGYTTAAFHGDVASFWNRDNAYKSWGYNYFFYSSYYKEKSDYNIGYGLKDKIFFKDS
VKYLEQLPQPFYAKLITLTNHYPYELDKKNQSIDKTTTGDSTVDGYVQTAHYLDQAFAEFISYLKKAGLYKNSMIVLYGD
HYGISNNHKAAIAQLLGKKSVTSFDLAQFQKVPFMIHSEGIKGGINHTYGGEIDALPTIFDLLGIKNKGYIQFGTDLLSK
QHNQTVAFRNGDFVSPTYTKISGTVYDSKTGKKLTDMTTKQKDTVKQMQNHVTTELSLSDRVIQGDLLRFYTPKGFKKVN
KSDYSYKLTKTLKSLKEIQAEKKTSVLSKHKGKSTESLYKTDAPELSSSSDSSSSSSSSSD

Sequences:

>Translated_701_residues
MPKFIKNTVGKVNTTLGFYLLTVVLFWLKTYIAYKSEFTLGVKGPVQEFILFLNPFPTAIVLLGIALYFRGRLKYWIMMI
IDALQTTWLFANILYYREFSDFMSAGVIKSSGAASNNLGKSLGQIIHGTDFLVYADVVLLILLLAFKVIRIDPRPFKIRY
AATLTMIGVALFAVDLGMSEHDRSDLLTRTFDNNYIVKYLGLNTYAGYSFYQTEKESATRAQASSSDMKSVLAYLKKNQA
GENVKYFGKAKGKNVFVIHLESFQQFLIDYKVDGKEVTPNLNKFYHDKSTLSFDNFYHQVAQGKTSDAEMMMENSLFGLP
TGSAMTQYGTSNTFQAAPAILSQKGYTTAAFHGDVASFWNRDNAYKSWGYNYFFYSSYYKEKSDYNIGYGLKDKIFFKDS
VKYLEQLPQPFYAKLITLTNHYPYELDKKNQSIDKTTTGDSTVDGYVQTAHYLDQAFAEFISYLKKAGLYKNSMIVLYGD
HYGISNNHKAAIAQLLGKKSVTSFDLAQFQKVPFMIHSEGIKGGINHTYGGEIDALPTIFDLLGIKNKGYIQFGTDLLSK
QHNQTVAFRNGDFVSPTYTKISGTVYDSKTGKKLTDMTTKQKDTVKQMQNHVTTELSLSDRVIQGDLLRFYTPKGFKKVN
KSDYSYKLTKTLKSLKEIQAEKKTSVLSKHKGKSTESLYKTDAPELSSSSDSSSSSSSSSD
>Mature_700_residues
PKFIKNTVGKVNTTLGFYLLTVVLFWLKTYIAYKSEFTLGVKGPVQEFILFLNPFPTAIVLLGIALYFRGRLKYWIMMII
DALQTTWLFANILYYREFSDFMSAGVIKSSGAASNNLGKSLGQIIHGTDFLVYADVVLLILLLAFKVIRIDPRPFKIRYA
ATLTMIGVALFAVDLGMSEHDRSDLLTRTFDNNYIVKYLGLNTYAGYSFYQTEKESATRAQASSSDMKSVLAYLKKNQAG
ENVKYFGKAKGKNVFVIHLESFQQFLIDYKVDGKEVTPNLNKFYHDKSTLSFDNFYHQVAQGKTSDAEMMMENSLFGLPT
GSAMTQYGTSNTFQAAPAILSQKGYTTAAFHGDVASFWNRDNAYKSWGYNYFFYSSYYKEKSDYNIGYGLKDKIFFKDSV
KYLEQLPQPFYAKLITLTNHYPYELDKKNQSIDKTTTGDSTVDGYVQTAHYLDQAFAEFISYLKKAGLYKNSMIVLYGDH
YGISNNHKAAIAQLLGKKSVTSFDLAQFQKVPFMIHSEGIKGGINHTYGGEIDALPTIFDLLGIKNKGYIQFGTDLLSKQ
HNQTVAFRNGDFVSPTYTKISGTVYDSKTGKKLTDMTTKQKDTVKQMQNHVTTELSLSDRVIQGDLLRFYTPKGFKKVNK
SDYSYKLTKTLKSLKEIQAEKKTSVLSKHKGKSTESLYKTDAPELSSSSDSSSSSSSSSD

Specific function: Catalyzes the polymerization of lipoteichoic acid (LTA) polyglycerol phosphate, a reaction that presumably uses phosphatidylglycerol (PG) as substrate [H]

COG id: COG1368

COG function: function code M; Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily

Gene ontology:

Cell location: Processed glycerol phosphate lipoteichoic acid synthase 1:Secreted. Note=The secretion into the extracellular medium is dependent on secA and ffh [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the LTA synthase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017849
- InterPro:   IPR017850
- InterPro:   IPR012160
- InterPro:   IPR000917 [H]

Pfam domain/function: PF00884 Sulfatase [H]

EC number: NA

Molecular weight: Translated: 79044; Mature: 78913

Theoretical pI: Translated: 9.72; Mature: 9.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKFIKNTVGKVNTTLGFYLLTVVLFWLKTYIAYKSEFTLGVKGPVQEFILFLNPFPTAI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHCCHHHHH
VLLGIALYFRGRLKYWIMMIIDALQTTWLFANILYYREFSDFMSAGVIKSSGAASNNLGK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHH
SLGQIIHGTDFLVYADVVLLILLLAFKVIRIDPRPFKIRYAATLTMIGVALFAVDLGMSE
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHEECCCCEEEEHHHHHHHHHHHHHHHHCCCCC
HDRSDLLTRTFDNNYIVKYLGLNTYAGYSFYQTEKESATRAQASSSDMKSVLAYLKKNQA
CCHHHHHHEECCCCEEEEEECCCCCCCCCEEECCHHHHHHHHCCHHHHHHHHHHHHHCCC
GENVKYFGKAKGKNVFVIHLESFQQFLIDYKVDGKEVTPNLNKFYHDKSTLSFDNFYHQV
CCCCEEEECCCCCEEEEEEHHHHHHHHHHEECCCCCCCCCHHHHHCCCCCCCHHHHHHHH
AQGKTSDAEMMMENSLFGLPTGSAMTQYGTSNTFQAAPAILSQKGYTTAAFHGDVASFWN
HCCCCCHHHHHHHCCCCCCCCCCHHHHCCCCCCHHHHHHHHHCCCCEEEEECCCHHHHHC
RDNAYKSWGYNYFFYSSYYKEKSDYNIGYGLKDKIFFKDSVKYLEQLPQPFYAKLITLTN
CCCCHHHCCCCEEEEEHHHCCCCCCCCCCCCCCCEEEHHHHHHHHHCCCHHHHHHHHHCC
HYPYELDKKNQSIDKTTTGDSTVDGYVQTAHYLDQAFAEFISYLKKAGLYKNSMIVLYGD
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECC
HYGISNNHKAAIAQLLGKKSVTSFDLAQFQKVPFMIHSEGIKGGINHTYGGEIDALPTIF
CCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHCCEEEECCCCCCCCCCCCCCCCCHHHHHH
DLLGIKNKGYIQFGTDLLSKQHNQTVAFRNGDFVSPTYTKISGTVYDSKTGKKLTDMTTK
HHHCCCCCCEEEECHHHHCCCCCCEEEEECCCCCCCCHHEEEEEEEECCCCCCHHHHHHH
QKDTVKQMQNHVTTELSLSDRVIQGDLLRFYTPKGFKKVNKSDYSYKLTKTLKSLKEIQA
HHHHHHHHHHHCCEEEECCCHHHHCCHHHHCCCCHHHHCCCCCCCCHHHHHHHHHHHHHH
EKKTSVLSKHKGKSTESLYKTDAPELSSSSDSSSSSSSSSD
HHHHHHHHHCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PKFIKNTVGKVNTTLGFYLLTVVLFWLKTYIAYKSEFTLGVKGPVQEFILFLNPFPTAI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHCCHHHHH
VLLGIALYFRGRLKYWIMMIIDALQTTWLFANILYYREFSDFMSAGVIKSSGAASNNLGK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHH
SLGQIIHGTDFLVYADVVLLILLLAFKVIRIDPRPFKIRYAATLTMIGVALFAVDLGMSE
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHEECCCCEEEEHHHHHHHHHHHHHHHHCCCCC
HDRSDLLTRTFDNNYIVKYLGLNTYAGYSFYQTEKESATRAQASSSDMKSVLAYLKKNQA
CCHHHHHHEECCCCEEEEEECCCCCCCCCEEECCHHHHHHHHCCHHHHHHHHHHHHHCCC
GENVKYFGKAKGKNVFVIHLESFQQFLIDYKVDGKEVTPNLNKFYHDKSTLSFDNFYHQV
CCCCEEEECCCCCEEEEEEHHHHHHHHHHEECCCCCCCCCHHHHHCCCCCCCHHHHHHHH
AQGKTSDAEMMMENSLFGLPTGSAMTQYGTSNTFQAAPAILSQKGYTTAAFHGDVASFWN
HCCCCCHHHHHHHCCCCCCCCCCHHHHCCCCCCHHHHHHHHHCCCCEEEEECCCHHHHHC
RDNAYKSWGYNYFFYSSYYKEKSDYNIGYGLKDKIFFKDSVKYLEQLPQPFYAKLITLTN
CCCCHHHCCCCEEEEEHHHCCCCCCCCCCCCCCCEEEHHHHHHHHHCCCHHHHHHHHHCC
HYPYELDKKNQSIDKTTTGDSTVDGYVQTAHYLDQAFAEFISYLKKAGLYKNSMIVLYGD
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECC
HYGISNNHKAAIAQLLGKKSVTSFDLAQFQKVPFMIHSEGIKGGINHTYGGEIDALPTIF
CCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHCCEEEECCCCCCCCCCCCCCCCCHHHHHH
DLLGIKNKGYIQFGTDLLSKQHNQTVAFRNGDFVSPTYTKISGTVYDSKTGKKLTDMTTK
HHHCCCCCCEEEECHHHHCCCCCCEEEEECCCCCCCCHHEEEEEEEECCCCCCHHHHHHH
QKDTVKQMQNHVTTELSLSDRVIQGDLLRFYTPKGFKKVNKSDYSYKLTKTLKSLKEIQA
HHHHHHHHHHHCCEEEECCCHHHHCCHHHHCCCCHHHHCCCCCCCCHHHHHHHHHHHHHH
EKKTSVLSKHKGKSTESLYKTDAPELSSSSDSSSSSSSSSD
HHHHHHHHHCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9141694; 9384377; 10658653 [H]