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The map label for this gene is galE2 [C]

Identifier: 28377974

GI number: 28377974

Start: 1093199

End: 1094146

Strand: Direct

Name: galE2 [C]

Synonym: lp_1200

Alternate gene names: 28377974

Gene position: 1093199-1094146 (Clockwise)

Preceding gene: 28377973

Following gene: 28377975

Centisome position: 33.04

GC content: 40.93

Gene sequence:

>948_bases
ATGAAAGCATTAGTAACTGGAGGAGCAGGATTTATTGGTTCCCACCTTGTGGATCACTTGGTCTCAGAAGGTTTGGACGT
TGTCGTAGTTGATAACTTGTCCATGGGGGACTTGCATAATATTAAGTATCAGGATGAAGTCACTATTTATGTTGAAGATG
TCCGCAACGAAAAATTCATGCAACAATTGCTACAGGAAGAACGGCCTGATTATATTTACTTTTTAGCAGCTGTTGCTAGT
GTTGCCGATTCGATTGAACGTCCAGCTGAAACCCATTCAGTGAATCAAACTGCAGTATTCAATATGTTGGAATATATTCG
GAAGACTAATTTACCAATTAAACAGTTCCTATTTACGTCTTCGGCAGCTGTTTACGGTAATCTTCCAGAATTACCTAAGA
AAGAAGACTCACGAGTTGATCCATTATCACCATATGCGATTGATAAGTATGCTACGGAACGTTTTGTACTAGCATATGGT
GAACTTTATGATTTACCAACTGTCTGTGTGCGTTTCTTCAATGTTTATGGCCCTGGTCAAAATCCCAGTTCGCCATATTC
AGGGGTGCTGTCGATCTTGACCGATTGTCTCAATAACAAGAAGCCATTTACCTTGTACGGAGACGGGAGTCAGACGCGAG
ATTTTGTGTATGTTGAAGATGTTATCCAAGCATTATGGTTGATAACGAAAAGTGATACTGAGCATGAAGTCTTTAATATC
GCTAATGGTAATGAAGCCAGCTTAAATGCTATTATTGAAACATATGAGAAGGTTGCAGAAACGTCATTGCAGATTAAAAA
GGCGCCAGGGCGTGAAGGGGAAGTAAAACGTTCGGTGGCCAACATCGGTAAGTTAATTAAGTTGGGATACACGACGAAGT
GGTCGTTAGAAGCGGGCTTGAGCAAATATTGGGAAGGGGCGCAACAACGTGAAGCAAGTCGAAATTAA

Upstream 100 bases:

>100_bases
CTCGGGATTTGTTGAATGGTGAACAGATTGAGATGGGGCAGATTGAGATACCACGAAAACAGCGAAAGCACTGGTTGTTC
TAAAAGAAGGAGCGAGTTAA

Downstream 100 bases:

>100_bases
TGAAACAGTTAAAGTTGGTCATGTACAACCACAAACGGATTATCGTTTTCCAACTATGATTGGAAAGCCAGTTACGGGCT
GGAAACTATTTGTAAAACGG

Product: UDP-glucose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 315; Mature: 315

Protein sequence:

>315_residues
MKALVTGGAGFIGSHLVDHLVSEGLDVVVVDNLSMGDLHNIKYQDEVTIYVEDVRNEKFMQQLLQEERPDYIYFLAAVAS
VADSIERPAETHSVNQTAVFNMLEYIRKTNLPIKQFLFTSSAAVYGNLPELPKKEDSRVDPLSPYAIDKYATERFVLAYG
ELYDLPTVCVRFFNVYGPGQNPSSPYSGVLSILTDCLNNKKPFTLYGDGSQTRDFVYVEDVIQALWLITKSDTEHEVFNI
ANGNEASLNAIIETYEKVAETSLQIKKAPGREGEVKRSVANIGKLIKLGYTTKWSLEAGLSKYWEGAQQREASRN

Sequences:

>Translated_315_residues
MKALVTGGAGFIGSHLVDHLVSEGLDVVVVDNLSMGDLHNIKYQDEVTIYVEDVRNEKFMQQLLQEERPDYIYFLAAVAS
VADSIERPAETHSVNQTAVFNMLEYIRKTNLPIKQFLFTSSAAVYGNLPELPKKEDSRVDPLSPYAIDKYATERFVLAYG
ELYDLPTVCVRFFNVYGPGQNPSSPYSGVLSILTDCLNNKKPFTLYGDGSQTRDFVYVEDVIQALWLITKSDTEHEVFNI
ANGNEASLNAIIETYEKVAETSLQIKKAPGREGEVKRSVANIGKLIKLGYTTKWSLEAGLSKYWEGAQQREASRN
>Mature_315_residues
MKALVTGGAGFIGSHLVDHLVSEGLDVVVVDNLSMGDLHNIKYQDEVTIYVEDVRNEKFMQQLLQEERPDYIYFLAAVAS
VADSIERPAETHSVNQTAVFNMLEYIRKTNLPIKQFLFTSSAAVYGNLPELPKKEDSRVDPLSPYAIDKYATERFVLAYG
ELYDLPTVCVRFFNVYGPGQNPSSPYSGVLSILTDCLNNKKPFTLYGDGSQTRDFVYVEDVIQALWLITKSDTEHEVFNI
ANGNEASLNAIIETYEKVAETSLQIKKAPGREGEVKRSVANIGKLIKLGYTTKWSLEAGLSKYWEGAQQREASRN

Specific function: DTDP-L-RHAMNOSE BIOSYNTHESIS WITHIN THE O ANTIGEN BIOSYNTHESIS PATHWAY OF LIPOPOLYSACCHARIDE BIOSYNTHESIS. [C]

COG id: COG0451

COG function: function code MG; Nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI7657641, Length=284, Percent_Identity=29.5774647887324, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI42516563, Length=310, Percent_Identity=28.3870967741935, Blast_Score=112, Evalue=5e-25,
Organism=Homo sapiens, GI56237023, Length=339, Percent_Identity=25.9587020648968, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI56118217, Length=339, Percent_Identity=25.9587020648968, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI189083684, Length=339, Percent_Identity=25.9587020648968, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI4504031, Length=263, Percent_Identity=25.0950570342205, Blast_Score=77, Evalue=2e-14,
Organism=Escherichia coli, GI1788353, Length=335, Percent_Identity=28.6567164179104, Blast_Score=117, Evalue=9e-28,
Organism=Escherichia coli, GI1786974, Length=308, Percent_Identity=26.6233766233766, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI48994969, Length=329, Percent_Identity=29.483282674772, Blast_Score=111, Evalue=5e-26,
Organism=Escherichia coli, GI1788366, Length=275, Percent_Identity=26.5454545454545, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1790049, Length=259, Percent_Identity=29.7297297297297, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1788365, Length=326, Percent_Identity=22.6993865030675, Blast_Score=70, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71982035, Length=338, Percent_Identity=29.2899408284024, Blast_Score=117, Evalue=8e-27,
Organism=Caenorhabditis elegans, GI71982038, Length=340, Percent_Identity=29.4117647058824, Blast_Score=117, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17539532, Length=255, Percent_Identity=30.1960784313725, Blast_Score=105, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI115532424, Length=276, Percent_Identity=26.4492753623188, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17568069, Length=257, Percent_Identity=31.9066147859922, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI133901786, Length=260, Percent_Identity=26.1538461538462, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI133901788, Length=260, Percent_Identity=26.1538461538462, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17507723, Length=259, Percent_Identity=26.2548262548263, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17539422, Length=260, Percent_Identity=26.1538461538462, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17539424, Length=260, Percent_Identity=26.1538461538462, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI133901790, Length=259, Percent_Identity=26.2548262548263, Blast_Score=77, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6319493, Length=337, Percent_Identity=24.3323442136499, Blast_Score=97, Evalue=4e-21,
Organism=Drosophila melanogaster, GI21356223, Length=310, Percent_Identity=29.0322580645161, Blast_Score=117, Evalue=9e-27,
Organism=Drosophila melanogaster, GI19923002, Length=340, Percent_Identity=26.7647058823529, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24158427, Length=262, Percent_Identity=22.5190839694656, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 35272; Mature: 35272

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKALVTGGAGFIGSHLVDHLVSEGLDVVVVDNLSMGDLHNIKYQDEVTIYVEDVRNEKFM
CCEEEECCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCEECCCEEEEEEHHCCHHHH
QQLLQEERPDYIYFLAAVASVADSIERPAETHSVNQTAVFNMLEYIRKTNLPIKQFLFTS
HHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHC
SAAVYGNLPELPKKEDSRVDPLSPYAIDKYATERFVLAYGELYDLPTVCVRFFNVYGPGQ
CCHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHEEEHHHHHCHHHHHHHHHHHCCCCC
NPSSPYSGVLSILTDCLNNKKPFTLYGDGSQTRDFVYVEDVIQALWLITKSDTEHEVFNI
CCCCHHHHHHHHHHHHHCCCCCEEEECCCCCCCCEEEHHHHHHHHHHHCCCCCCCCEEEC
ANGNEASLNAIIETYEKVAETSLQIKKAPGREGEVKRSVANIGKLIKLGYTTKWSLEAGL
CCCCCHHHHHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHHCCCCEEHHHHHH
SKYWEGAQQREASRN
HHHHCCHHHHHCCCC
>Mature Secondary Structure
MKALVTGGAGFIGSHLVDHLVSEGLDVVVVDNLSMGDLHNIKYQDEVTIYVEDVRNEKFM
CCEEEECCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCEECCCEEEEEEHHCCHHHH
QQLLQEERPDYIYFLAAVASVADSIERPAETHSVNQTAVFNMLEYIRKTNLPIKQFLFTS
HHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHC
SAAVYGNLPELPKKEDSRVDPLSPYAIDKYATERFVLAYGELYDLPTVCVRFFNVYGPGQ
CCHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHEEEHHHHHCHHHHHHHHHHHCCCCC
NPSSPYSGVLSILTDCLNNKKPFTLYGDGSQTRDFVYVEDVIQALWLITKSDTEHEVFNI
CCCCHHHHHHHHHHHHHCCCCCEEEECCCCCCCCEEEHHHHHHHHHHHCCCCCCCCEEEC
ANGNEASLNAIIETYEKVAETSLQIKKAPGREGEVKRSVANIGKLIKLGYTTKWSLEAGL
CCCCCHHHHHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHHCCCCEEHHHHHH
SKYWEGAQQREASRN
HHHHCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]