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The map label for this gene is yfnA [H]

Identifier: 28377907

GI number: 28377907

Start: 1018290

End: 1019717

Strand: Direct

Name: yfnA [H]

Synonym: lp_1120

Alternate gene names: 28377907

Gene position: 1018290-1019717 (Clockwise)

Preceding gene: 28377906

Following gene: 28377908

Centisome position: 30.78

GC content: 45.73

Gene sequence:

>1428_bases
ATGAAAGCATCACAACGATTGCTGGTTAAAAAATCAGTCAATCCAGCTAATTTTAATAAGGGTGGCCTCGAAAAGACGTT
GAGCGCATTTAGTTTAACCATGATGGGTGTTGGCGCAATCGTGGGTTCTGGGATTTTTATCACACCCGGAATTATCGCCG
CTAAGTATGCCGGTCCGGCTGCCATGCTCTCATTTGTGATTGCTGCGGTCGTGTGTTCGTTGGCCGCATTATGTTACGCT
GAATTTTCTTCAACCATTCCCTTGGCGGGGAGTGCCTATACTTACGTTTATACCGTTTTTGGGGAATTCTTAGCGTGGAT
TCTTGGTTGGTCTCTGATCTCAGAATATTTATTCGCGGTATCTTCGGTGGCAGTAAGTTGGTCATCGTACTTTCAGAATT
TAATGAGCGGCTTTGGCCTAAAACTACCAACATTTCTGACCGCCGCAGCTGGTACTGCCGGTGTCAGTGGTGCTGGATTC
AACTTAATTGCTTTTGTCGTGGTTTTGGCCGTCTCACTGTTATTGGTCGGTGGGCTACAAGAGTCAACACGGGTCAATTC
AATTATGGTAATCGTTAAGATTCTAGTGATTGTTCTTTTCATTGGCGTGGCAATTTTCTTTGTGAAACCTGCCAATTATC
ATCCGTTCATGCCCCATGGTGTTAGCGGACTGGTCAAAGGCGCGTCGTTAGCATTCTACGCGTATATTGGGTTTGATGCG
GTGTCGACTGCTTCAGAAGAAGTGAAAAATCCTAAGCGTAATATGCCAATCGGAATTGTCGGTTCGTTAGTCGTAGCATC
GATTTTATACGTGGCAATGGCCGCCGTTCTGGTCGGGGTCGTGCATTACAGTAAGCTTAACGTGGGTGATCCCGTGGCGT
ATGCCTTAGCCGTCATTCATCAAAACTGGGCGGCGGGGATTGTGTCACTGGGTGCCGTTGTCGGTATGACGACCGTTTTG
ATTGTCATGTTATATGGTGGGACCCGGTTACTGTTTGCGATTAGCCGGGATGGGTTGTTACCGAAAGTCTTTCGGACGGT
CAGTCCCCATACCAAAGTGCCAGTTAAGAGTACTTGGATTTTTGGCATTATTGCCAGTGTATTTGCGGCTGTGATTCCAT
TAGATAAAATTGCGGAGTTAGTCAATATTGGAACGCTATTTGCATTCGCTATGGTGTCTATCGGTGTTGTCTTCCTGCGT
CGACACGAAACGCTACAACAAATCAATAGTTCATTTAAAGTACCATTTTATCCAGTGTTACCAGTTGTCTCGTTCCTCGC
ATGTGTCTACCTGATGCTTAATTTGCAGGCATTTACGTGGCATATGTTTGGTATTTGGCTGGTTATTGGCATCGTGATTT
ACTTTGCCTATAGTTATCGGCACTCCCGTATTCGAGCAGGGTTACGTGCCAAAGAATCAAAATCGTAA

Upstream 100 bases:

>100_bases
GGAATTGATTGAAATTGTTAGATTTACTTGACTAATTGCACAAAAATTAATAGAATTAACAACGTTGCATTATTAAGATT
TTGATTAGGAGGCGTACCGG

Downstream 100 bases:

>100_bases
TTAATAGTGGGTGCTTACCGGGGCGGGTAAGCACCCATTCTTTTCGCGGCTACTAAGCTTTGGGATATGCTATAATTAAG
CGCATAATTCATAAGGTAAA

Product: amino acid transport protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 475; Mature: 475

Protein sequence:

>475_residues
MKASQRLLVKKSVNPANFNKGGLEKTLSAFSLTMMGVGAIVGSGIFITPGIIAAKYAGPAAMLSFVIAAVVCSLAALCYA
EFSSTIPLAGSAYTYVYTVFGEFLAWILGWSLISEYLFAVSSVAVSWSSYFQNLMSGFGLKLPTFLTAAAGTAGVSGAGF
NLIAFVVVLAVSLLLVGGLQESTRVNSIMVIVKILVIVLFIGVAIFFVKPANYHPFMPHGVSGLVKGASLAFYAYIGFDA
VSTASEEVKNPKRNMPIGIVGSLVVASILYVAMAAVLVGVVHYSKLNVGDPVAYALAVIHQNWAAGIVSLGAVVGMTTVL
IVMLYGGTRLLFAISRDGLLPKVFRTVSPHTKVPVKSTWIFGIIASVFAAVIPLDKIAELVNIGTLFAFAMVSIGVVFLR
RHETLQQINSSFKVPFYPVLPVVSFLACVYLMLNLQAFTWHMFGIWLVIGIVIYFAYSYRHSRIRAGLRAKESKS

Sequences:

>Translated_475_residues
MKASQRLLVKKSVNPANFNKGGLEKTLSAFSLTMMGVGAIVGSGIFITPGIIAAKYAGPAAMLSFVIAAVVCSLAALCYA
EFSSTIPLAGSAYTYVYTVFGEFLAWILGWSLISEYLFAVSSVAVSWSSYFQNLMSGFGLKLPTFLTAAAGTAGVSGAGF
NLIAFVVVLAVSLLLVGGLQESTRVNSIMVIVKILVIVLFIGVAIFFVKPANYHPFMPHGVSGLVKGASLAFYAYIGFDA
VSTASEEVKNPKRNMPIGIVGSLVVASILYVAMAAVLVGVVHYSKLNVGDPVAYALAVIHQNWAAGIVSLGAVVGMTTVL
IVMLYGGTRLLFAISRDGLLPKVFRTVSPHTKVPVKSTWIFGIIASVFAAVIPLDKIAELVNIGTLFAFAMVSIGVVFLR
RHETLQQINSSFKVPFYPVLPVVSFLACVYLMLNLQAFTWHMFGIWLVIGIVIYFAYSYRHSRIRAGLRAKESKS
>Mature_475_residues
MKASQRLLVKKSVNPANFNKGGLEKTLSAFSLTMMGVGAIVGSGIFITPGIIAAKYAGPAAMLSFVIAAVVCSLAALCYA
EFSSTIPLAGSAYTYVYTVFGEFLAWILGWSLISEYLFAVSSVAVSWSSYFQNLMSGFGLKLPTFLTAAAGTAGVSGAGF
NLIAFVVVLAVSLLLVGGLQESTRVNSIMVIVKILVIVLFIGVAIFFVKPANYHPFMPHGVSGLVKGASLAFYAYIGFDA
VSTASEEVKNPKRNMPIGIVGSLVVASILYVAMAAVLVGVVHYSKLNVGDPVAYALAVIHQNWAAGIVSLGAVVGMTTVL
IVMLYGGTRLLFAISRDGLLPKVFRTVSPHTKVPVKSTWIFGIIASVFAAVIPLDKIAELVNIGTLFAFAMVSIGVVFLR
RHETLQQINSSFKVPFYPVLPVVSFLACVYLMLNLQAFTWHMFGIWLVIGIVIYFAYSYRHSRIRAGLRAKESKS

Specific function: Probable Amino-Acid Or Metabolite Transport Protein. [C]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Homo sapiens, GI181337167, Length=386, Percent_Identity=34.4559585492228, Blast_Score=218, Evalue=1e-56,
Organism=Homo sapiens, GI4507047, Length=428, Percent_Identity=34.1121495327103, Blast_Score=215, Evalue=6e-56,
Organism=Homo sapiens, GI258614005, Length=430, Percent_Identity=33.7209302325581, Blast_Score=211, Evalue=2e-54,
Organism=Homo sapiens, GI258614003, Length=430, Percent_Identity=33.7209302325581, Blast_Score=210, Evalue=2e-54,
Organism=Homo sapiens, GI258645169, Length=430, Percent_Identity=34.4186046511628, Blast_Score=210, Evalue=2e-54,
Organism=Homo sapiens, GI110347453, Length=405, Percent_Identity=33.3333333333333, Blast_Score=207, Evalue=3e-53,
Organism=Homo sapiens, GI114326544, Length=431, Percent_Identity=31.0904872389791, Blast_Score=201, Evalue=1e-51,
Organism=Homo sapiens, GI114326550, Length=431, Percent_Identity=31.0904872389791, Blast_Score=201, Evalue=1e-51,
Organism=Homo sapiens, GI187423910, Length=477, Percent_Identity=25.5765199161426, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI7657591, Length=477, Percent_Identity=25.5765199161426, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI186910308, Length=418, Percent_Identity=25.8373205741627, Blast_Score=102, Evalue=6e-22,
Organism=Homo sapiens, GI186910306, Length=418, Percent_Identity=25.8373205741627, Blast_Score=102, Evalue=6e-22,
Organism=Homo sapiens, GI186910304, Length=418, Percent_Identity=25.8373205741627, Blast_Score=102, Evalue=6e-22,
Organism=Homo sapiens, GI115648063, Length=430, Percent_Identity=23.4883720930233, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI115648022, Length=430, Percent_Identity=23.4883720930233, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI71979932, Length=452, Percent_Identity=26.5486725663717, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI33286428, Length=365, Percent_Identity=24.6575342465753, Blast_Score=81, Evalue=3e-15,
Organism=Homo sapiens, GI7657683, Length=380, Percent_Identity=21.5789473684211, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI87081869, Length=480, Percent_Identity=25.2083333333333, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI87082023, Length=462, Percent_Identity=25.5411255411255, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI87082250, Length=401, Percent_Identity=24.9376558603491, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI87081708, Length=433, Percent_Identity=21.0161662817552, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI2367353, Length=356, Percent_Identity=29.2134831460674, Blast_Score=85, Evalue=8e-18,
Organism=Escherichia coli, GI1786302, Length=471, Percent_Identity=21.4437367303609, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1788480, Length=456, Percent_Identity=22.3684210526316, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1786789, Length=445, Percent_Identity=21.3483146067416, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1786602, Length=417, Percent_Identity=22.0623501199041, Blast_Score=65, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17532491, Length=438, Percent_Identity=33.5616438356164, Blast_Score=237, Evalue=8e-63,
Organism=Caenorhabditis elegans, GI17533459, Length=412, Percent_Identity=33.0097087378641, Blast_Score=205, Evalue=4e-53,
Organism=Caenorhabditis elegans, GI17531343, Length=411, Percent_Identity=31.8734793187348, Blast_Score=205, Evalue=5e-53,
Organism=Caenorhabditis elegans, GI17540018, Length=457, Percent_Identity=25.382932166302, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI71982612, Length=406, Percent_Identity=24.1379310344828, Blast_Score=100, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI71982608, Length=406, Percent_Identity=24.6305418719212, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17568033, Length=349, Percent_Identity=26.3610315186246, Blast_Score=95, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI32566699, Length=370, Percent_Identity=22.7027027027027, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI32566695, Length=420, Percent_Identity=22.3809523809524, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI193208714, Length=420, Percent_Identity=22.3809523809524, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI71993915, Length=387, Percent_Identity=21.4470284237726, Blast_Score=78, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI71995382, Length=445, Percent_Identity=22.4719101123595, Blast_Score=77, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI71995388, Length=445, Percent_Identity=22.4719101123595, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI71982623, Length=266, Percent_Identity=25.187969924812, Blast_Score=76, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17537453, Length=306, Percent_Identity=24.1830065359477, Blast_Score=72, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI71990446, Length=455, Percent_Identity=22.4175824175824, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24667468, Length=409, Percent_Identity=34.9633251833741, Blast_Score=268, Evalue=5e-72,
Organism=Drosophila melanogaster, GI221512776, Length=412, Percent_Identity=36.8932038834951, Blast_Score=257, Evalue=1e-68,
Organism=Drosophila melanogaster, GI24666159, Length=412, Percent_Identity=36.8932038834951, Blast_Score=257, Evalue=1e-68,
Organism=Drosophila melanogaster, GI24668806, Length=424, Percent_Identity=33.0188679245283, Blast_Score=239, Evalue=3e-63,
Organism=Drosophila melanogaster, GI21356285, Length=424, Percent_Identity=33.0188679245283, Blast_Score=239, Evalue=3e-63,
Organism=Drosophila melanogaster, GI24668802, Length=424, Percent_Identity=33.0188679245283, Blast_Score=239, Evalue=3e-63,
Organism=Drosophila melanogaster, GI161077963, Length=389, Percent_Identity=33.9331619537275, Blast_Score=206, Evalue=3e-53,
Organism=Drosophila melanogaster, GI281366235, Length=419, Percent_Identity=31.5035799522673, Blast_Score=197, Evalue=2e-50,
Organism=Drosophila melanogaster, GI116007820, Length=419, Percent_Identity=31.5035799522673, Blast_Score=197, Evalue=2e-50,
Organism=Drosophila melanogaster, GI116007818, Length=413, Percent_Identity=31.9612590799031, Blast_Score=192, Evalue=3e-49,
Organism=Drosophila melanogaster, GI85725152, Length=413, Percent_Identity=31.9612590799031, Blast_Score=192, Evalue=3e-49,
Organism=Drosophila melanogaster, GI221331183, Length=484, Percent_Identity=23.9669421487603, Blast_Score=96, Evalue=5e-20,
Organism=Drosophila melanogaster, GI17647653, Length=484, Percent_Identity=23.9669421487603, Blast_Score=96, Evalue=5e-20,
Organism=Drosophila melanogaster, GI24664379, Length=484, Percent_Identity=23.9669421487603, Blast_Score=96, Evalue=5e-20,
Organism=Drosophila melanogaster, GI24651635, Length=408, Percent_Identity=23.7745098039216, Blast_Score=89, Evalue=6e-18,
Organism=Drosophila melanogaster, GI24651633, Length=408, Percent_Identity=23.7745098039216, Blast_Score=89, Evalue=6e-18,
Organism=Drosophila melanogaster, GI21357367, Length=444, Percent_Identity=21.8468468468468, Blast_Score=86, Evalue=7e-17,
Organism=Drosophila melanogaster, GI45550968, Length=486, Percent_Identity=23.8683127572016, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI19921172, Length=486, Percent_Identity=23.8683127572016, Blast_Score=84, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR015606 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 50782; Mature: 50782

Theoretical pI: Translated: 10.17; Mature: 10.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9141694; 9384377 [H]