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The map label for this gene is aroD1 [H]

Identifier: 28377877

GI number: 28377877

Start: 986628

End: 987521

Strand: Direct

Name: aroD1 [H]

Synonym: lp_1084

Alternate gene names: 28377877

Gene position: 986628-987521 (Clockwise)

Preceding gene: 28377876

Following gene: 28377878

Centisome position: 29.82

GC content: 50.78

Gene sequence:

>894_bases
ATGATTGATGGACAAACGGCACTCTTTGGATTTATCGCGCACCCCGCGCGGCACAGTCGCTCACCGCGAATGCATAATTT
GAGTTTTGACTACTGGGGGCTAAATGCGCGCTACTTGGCGTTTGATGTGGCACCGGATGGATTGGCTGGTACGCTTGCTG
GAATTCGTAGCATGGGTATCGCGGGGGTGAACCTTTCAATGCCATTCAAACAAACCGTTGTACCGCTACTAGATGGTTTG
ACAGTGCGAGCGCAACGGATTCAAGCGGTCAATACGATTAAGAATGAAGCTGGCAAGCTGATTGGTGACAGCACGGACGG
CGCTGGAGTTTTTCAGGATCTCTTACATCAAGGTCTGAACTTGGTTGATAAGCACGTCATGGTTTTAGGCGCGGGAGGCG
CAGGTAAGGCAATCATTGCGGCGGCTTTAGATTATGGTGTCGCGAGTGTAACGGTCTTTAAACGCAACAACGAACGCTAC
GCCGGTGTTCAGCACTGGTTGGAGCAACTCAGTACCACGACTTCGGTACCACTCCGGCTCTGTGCCTATGAAGACCAAGT
ACGGATGCAGCAAGTTGCTCGTACCAGCAATTTGATCATTAACGCGACCAATATCGGCATGACGACTGCTGGAACGCCAT
TACCAATCTCAATTATCCAGCAATTAGTCCCACAACAGACGGTCTATGATGTGATTTACCAACCGCTAGAAACGACCTTT
TTGCGCTTAGCGCGTCAGCAGGGGTGCGCCACATATAATGGTTTGGGGATGTTGATTTGGCAAGGTGCCTTGGCTTTTGA
GTTTTGGACTGGTAAGCAGATGCCAGTTCAACAGGTCCGCCAAGATATGTTAGCCAGTATTCAAGCGACTCCGCCGATTA
CGGCGCAGGCTTAG

Upstream 100 bases:

>100_bases
AACCAGTTCACGGTAGCAGACCTAGTGCGGACGTATCAACAAACGCACGTGGATCTTGGTCAACAATTGCGAGTCATTTA
GAAAGGAAGTTAGTTAAAGC

Downstream 100 bases:

>100_bases
GCCTTAACTTTTGAGAATTGATTAGTAGGAGGAAATTATTATGATTATTATATTAAAACCAGCAACCGCTACGGCTATGC
AGGCAAAGTTAGTGAGTCAA

Product: shikimate 5-dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 297; Mature: 297

Protein sequence:

>297_residues
MIDGQTALFGFIAHPARHSRSPRMHNLSFDYWGLNARYLAFDVAPDGLAGTLAGIRSMGIAGVNLSMPFKQTVVPLLDGL
TVRAQRIQAVNTIKNEAGKLIGDSTDGAGVFQDLLHQGLNLVDKHVMVLGAGGAGKAIIAAALDYGVASVTVFKRNNERY
AGVQHWLEQLSTTTSVPLRLCAYEDQVRMQQVARTSNLIINATNIGMTTAGTPLPISIIQQLVPQQTVYDVIYQPLETTF
LRLARQQGCATYNGLGMLIWQGALAFEFWTGKQMPVQQVRQDMLASIQATPPITAQA

Sequences:

>Translated_297_residues
MIDGQTALFGFIAHPARHSRSPRMHNLSFDYWGLNARYLAFDVAPDGLAGTLAGIRSMGIAGVNLSMPFKQTVVPLLDGL
TVRAQRIQAVNTIKNEAGKLIGDSTDGAGVFQDLLHQGLNLVDKHVMVLGAGGAGKAIIAAALDYGVASVTVFKRNNERY
AGVQHWLEQLSTTTSVPLRLCAYEDQVRMQQVARTSNLIINATNIGMTTAGTPLPISIIQQLVPQQTVYDVIYQPLETTF
LRLARQQGCATYNGLGMLIWQGALAFEFWTGKQMPVQQVRQDMLASIQATPPITAQA
>Mature_297_residues
MIDGQTALFGFIAHPARHSRSPRMHNLSFDYWGLNARYLAFDVAPDGLAGTLAGIRSMGIAGVNLSMPFKQTVVPLLDGL
TVRAQRIQAVNTIKNEAGKLIGDSTDGAGVFQDLLHQGLNLVDKHVMVLGAGGAGKAIIAAALDYGVASVTVFKRNNERY
AGVQHWLEQLSTTTSVPLRLCAYEDQVRMQQVARTSNLIINATNIGMTTAGTPLPISIIQQLVPQQTVYDVIYQPLETTF
LRLARQQGCATYNGLGMLIWQGALAFEFWTGKQMPVQQVRQDMLASIQATPPITAQA

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; fourth step. [C]

COG id: COG0169

COG function: function code E; Shikimate 5-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1787983, Length=276, Percent_Identity=34.0579710144928, Blast_Score=177, Evalue=8e-46,
Organism=Escherichia coli, GI1789675, Length=285, Percent_Identity=29.8245614035088, Blast_Score=105, Evalue=4e-24,
Organism=Saccharomyces cerevisiae, GI6320332, Length=286, Percent_Identity=24.1258741258741, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR013708
- InterPro:   IPR022893
- InterPro:   IPR006151 [H]

Pfam domain/function: PF01488 Shikimate_DH; PF08501 Shikimate_dh_N [H]

EC number: =1.1.1.25 [H]

Molecular weight: Translated: 32222; Mature: 32222

Theoretical pI: Translated: 9.03; Mature: 9.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDGQTALFGFIAHPARHSRSPRMHNLSFDYWGLNARYLAFDVAPDGLAGTLAGIRSMGI
CCCCHHHHHHHHHCHHHCCCCCCCCCCCCEEECCCEEEEEEECCCCCHHHHHHHHHHCCC
AGVNLSMPFKQTVVPLLDGLTVRAQRIQAVNTIKNEAGKLIGDSTDGAGVFQDLLHQGLN
CCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
LVDKHVMVLGAGGAGKAIIAAALDYGVASVTVFKRNNERYAGVQHWLEQLSTTTSVPLRL
HHCCEEEEEECCCCCHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHCCCCCCEEE
CAYEDQVRMQQVARTSNLIINATNIGMTTAGTPLPISIIQQLVPQQTVYDVIYQPLETTF
ECCHHHHHHHHHHHHCCEEEEEECCCEECCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHH
LRLARQQGCATYNGLGMLIWQGALAFEFWTGKQMPVQQVRQDMLASIQATPPITAQA
HHHHHHCCCCCCCCCCCEEECCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MIDGQTALFGFIAHPARHSRSPRMHNLSFDYWGLNARYLAFDVAPDGLAGTLAGIRSMGI
CCCCHHHHHHHHHCHHHCCCCCCCCCCCCEEECCCEEEEEEECCCCCHHHHHHHHHHCCC
AGVNLSMPFKQTVVPLLDGLTVRAQRIQAVNTIKNEAGKLIGDSTDGAGVFQDLLHQGLN
CCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
LVDKHVMVLGAGGAGKAIIAAALDYGVASVTVFKRNNERYAGVQHWLEQLSTTTSVPLRL
HHCCEEEEEECCCCCHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHCCCCCCEEE
CAYEDQVRMQQVARTSNLIINATNIGMTTAGTPLPISIIQQLVPQQTVYDVIYQPLETTF
ECCHHHHHHHHHHHHCCEEEEEECCCEECCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHH
LRLARQQGCATYNGLGMLIWQGALAFEFWTGKQMPVQQVRQDMLASIQATPPITAQA
HHHHHHCCCCCCCCCCCEEECCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA