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The map label for this gene is rpoB

Identifier: 28377825

GI number: 28377825

Start: 939961

End: 943575

Strand: Direct

Name: rpoB

Synonym: lp_1021

Alternate gene names: 28377825

Gene position: 939961-943575 (Clockwise)

Preceding gene: 28377824

Following gene: 28377826

Centisome position: 28.41

GC content: 45.92

Gene sequence:

>3615_bases
GTGAACAACTTGGCCGGACATTTAGTAAAATACGGTAAACACCGTACCCGTAGAAGTTATGCACGTATCAAGGAAGTTCT
TGATTTGCCTAACTTGATCGAAATCCAGACCGATTCTTACCAATGGTTCTTGGATGAAGGTCTCCGGGAAATGTTTGAAG
ATATTATGCCGATCGACGATTTCGCAGGAAAACTTTCACTTGAATTTGTCGACTATCAATTATTAGAACCAAAGTACACC
GTCGAAGAAGCTCGTGAACATGATGCCAACTACTCGGCACCATTGCACGTTACCCTACGTTTAACTAACCATGAAACTGG
TGAAATTAAGTCGCAAGACGTATTCTTCGGTGATTTTCCATTAATGACTGAACAAGGGACGTTTATTATCAACGGTGCCG
AACGGGTCATTGTTTCACAATTGGTTCGTTCACCCGGCGTTTACTTCAATGAAGAATTAGATAAAAATGGGCGTCCTAGC
TACGGCACAACGGTTATTCCTAACCGGGGTGCTTGGTTAGAACTTGAAACTGACGCCAAGAATGTCTCATACGTACGGAT
CGACCGTACGCGGAAGATTCCATTGACGGAATTAGTCCGGGCCTTAGGCTATGGTTCTGACGATGACATTATTGACATGT
TGGGTGAAACTGACAGTTTGATGTTGACGTTGGAAAAGGACGTTCATAAGAACACCGACGACTCCCGGGTTGAAGAATCC
TTAAAAGATATCTACGAACGGCTACGTCCTGGTGAACCTAAGACGGCTGACAGTTCGCGGAGCCTATTGACTGCTCGGTT
CTTCGATCCAAAACGGTATGACTTCGCACCAGTTGGTCGCTACAAGGTTAACAAGAAGTTAAGCATGAAGACGCGCTTAA
TGGACCAAACGTTAGCTGAGACATTAGCTGATCCTGATACTGGTGAAGTTATTGCGCAAAAGGATACGGTCATTGACAAG
AATGTCATGGCTAAACTATCCCCATACTTGGAACGTGACGACTTTAAGACGGTTACTTACACACCATCTGACGAAGCCGT
TGTTACGAATCCAATGGTCTTACAAGTTGTTAAGGTTTATTCACAAAACGACCCTGAAAAGGTTGTGAACGTGATTGGTA
ATGGCAACATTGATTTGAAGTTCAAGCACATTGTGCCTGCTGATATCATTGCTTCCATTAATTACTTCTTCAACTTGCAA
GAAGGTCTTGGCTCAACCGATGATATTGATCACTTGGGTAACCGGCGGATTCGTTCCGTGGGTGAATTATTGCAAAACCA
ATTCCGGATTGGGTTATCCCGGATGGAACGGGTTGTGCGTGAACGGATGTCGATTCAAGATGCTGCGACGGTAACGCCAC
AACAATTGATTAACATTCGCCCAGTGGTTGCTTCAATTAAGGAATTCTTTGGGTCATCACAATTGTCACAATTCATGGAC
CAAACCAACCCCTTAGGTGAATTAACGCATAAGCGGCGTTTATCAGCCTTAGGACCTGGTGGTTTGACTCGTGATCGGGC
CGGATATGAAGTTCGTGACGTGCACTATACCCACTACGGTCGGATGTGCCCAATCGAAACGCCTGAAGGCCCTAACATTG
GTTTGATCAACAGTTTGTCTTCTTATGCGAAGGTCAACCGTTCCGGCTTCATCGAAACGCCATACCGGCGTGTCGATTGG
ACAACGCATAAGGTTACCGATAAGATCGACTACTTAGCAGCCGATGAAGAAGACCAATTTGTGATTGCACAAGCCAACTC
TCCATTGAATGATGATGGTTCTTTCGTTGAAGACACTGTTTTAGCTCGTAACAAGGAAGAAAACTTGGAAACGCCAATCG
AAAATGTCGATTACATGGACGTTTCGCCTAAACAAGTGGTTGCCGTCGCAACGGCATGTATTCCTTTCTTGGAAAACGAT
GACTCTAACCGTGCTTTGATGGGTGCCAACATGCAACGACAAGCGGTGCCGTTACTTGATCCTCACGCGCCATTAATTGG
GACTGGGATTGAATATAAAGCTGCACATGACTCAGGGATTGCCTTGATTTGTCGTCATGAAGGAACGGTTGAATACGTTG
ATGCTCGCGAAGTTCGCGTTCGTCGCGATGATGGTTCATTAGACACTTACAAGTTAATGAAATTCCGTCGTTCTAACGGT
GGTAAGAACTATAACCAACGGCCAATCGTTAAAGTTGGCGATCACGTTGATAACGATGAAGTCTTAGCCGATGGTCCAGC
AATGGAAGGTGGGGAATTAGCCCTTGGGCAAAACCCATTAGTTGCCTTCATGACTTGGAATGGTTATAACTTCGAAGATG
CCATCATTATTAATGAACGTTTAGTCCGTGAAGACGTCTACACGTCAATTCATATTGAAGAATATGAATCAGAAGCACGT
GACACCAAGCTTGGACCTGAAGAAATGACTCGTGAAATTCCTAACGTCGGGGAAGATGCATTGAAGAACCTTGACGAAGA
CGGGATTATCCGGATTGGGGCCGAAGTTAAAGACGGTGACATCTTGGTTGGTAAGGTAACGCCTAAAGGGGTTACGGAAT
TGTCAGCTGAAGAACGGCTTCTCCATGCGATCTTTGGTGAAAAGGCGCGTGAAGTTCGGGATACGTCACTCCGGGTTCCT
CATGGTGGCGGCGGTATCATCCAGGACGTTAAGATCTTCACTCGTGAAAACGGTGATGAATTATCTCCTGGCGTTAACAT
GATGGTTCGGGTCTACATCGCACAAAAGCGGAAGATCCAAGTTGGTGACAAGATGGCCGGTCGGCATGGTAACAAAGGGA
CGGTTTCAATCGTGGTTCCTGAAGAAGACATGCCGTACATGCCTGATGGAACACCAATCGATATCATGTTAAGCCCAATG
GGTGTGCCTTCTCGTATGAATATCGGGCAAGTGCTCGAATTGCATTTGGGGATGGCTGCTCGGAAGTTAGGAATTCACAT
GGCAACGCCTGTCTTTGATGGTGCTCAAGATACAGATATTTGGGAAGCCATTCGTGAAGCTGGGGTTGATTCAGATGCCA
AGTCGATCGTCTATGATGGTCGGACTGGTGAACCGTTCGATAAGCGGGTCGCTGTTGGGGTCATGCACTACATGAAGCTT
AGTCACATGGTTGACGATAAGATCCATGCTCGTTCAATCGGACCTTACTCTTTGGTTACGCAACAACCACTTGGTGGGAA
AGCGCAATTTGGGGGCCAACGTTTCGGTGAAATGGAAGTTTGGGCCTTGGAAGCTTATGGTGCAGCTTATACCTTGCAGG
AAATCTTGACTTACAAGTCCGATGACGTTGTTGGTCGGGTTAAGACCTATGAAGCAATCGTTAAGGGCGAACCAATTCCA
AAGCCTGGCGTACCGGAATCATTCCGCGTGTTGGTTAAGGAATTGCAAGCACTCGGTCTTGACATGAAAGTCTTGGATTC
TGAAGACAAAGAAATCGAATTGCGGGACATGGATGATGATGACGATGAAGTTGTCAATGTCGATGCACTCAGCAAGTTTA
AACAACAACAAGATGAGAAGGCTGCGGACAAGGCCGCAAAAGCTGACGCCGCTAAGCCTTCTGAAACAACCAACGCTCAG
CAAGATAATCAATAA

Upstream 100 bases:

>100_bases
ATTTTTGGTTTTTTTATGCCTAAAATTCGGTCAAAAACGCATTTGTAACACAAATGTAATATTTGGCCGGAGGTGGCGGG
TTCCGGAATAATAAGAAGGG

Downstream 100 bases:

>100_bases
AAAGGGAGGTCGGTCCTTTGATCGATGTCAACAAGTTTGAAAGCATGCAAATCGGTCTGGCATCCCCAGACAAGATTCGC
AGCTGGTCATATGGCGAAGT

Product: DNA-directed RNA polymerase subunit beta

Products: NA

Alternate protein names: RNAP subunit beta; RNA polymerase subunit beta; Transcriptase subunit beta

Number of amino acids: Translated: 1204; Mature: 1204

Protein sequence:

>1204_residues
MNNLAGHLVKYGKHRTRRSYARIKEVLDLPNLIEIQTDSYQWFLDEGLREMFEDIMPIDDFAGKLSLEFVDYQLLEPKYT
VEEAREHDANYSAPLHVTLRLTNHETGEIKSQDVFFGDFPLMTEQGTFIINGAERVIVSQLVRSPGVYFNEELDKNGRPS
YGTTVIPNRGAWLELETDAKNVSYVRIDRTRKIPLTELVRALGYGSDDDIIDMLGETDSLMLTLEKDVHKNTDDSRVEES
LKDIYERLRPGEPKTADSSRSLLTARFFDPKRYDFAPVGRYKVNKKLSMKTRLMDQTLAETLADPDTGEVIAQKDTVIDK
NVMAKLSPYLERDDFKTVTYTPSDEAVVTNPMVLQVVKVYSQNDPEKVVNVIGNGNIDLKFKHIVPADIIASINYFFNLQ
EGLGSTDDIDHLGNRRIRSVGELLQNQFRIGLSRMERVVRERMSIQDAATVTPQQLINIRPVVASIKEFFGSSQLSQFMD
QTNPLGELTHKRRLSALGPGGLTRDRAGYEVRDVHYTHYGRMCPIETPEGPNIGLINSLSSYAKVNRSGFIETPYRRVDW
TTHKVTDKIDYLAADEEDQFVIAQANSPLNDDGSFVEDTVLARNKEENLETPIENVDYMDVSPKQVVAVATACIPFLEND
DSNRALMGANMQRQAVPLLDPHAPLIGTGIEYKAAHDSGIALICRHEGTVEYVDAREVRVRRDDGSLDTYKLMKFRRSNG
GKNYNQRPIVKVGDHVDNDEVLADGPAMEGGELALGQNPLVAFMTWNGYNFEDAIIINERLVREDVYTSIHIEEYESEAR
DTKLGPEEMTREIPNVGEDALKNLDEDGIIRIGAEVKDGDILVGKVTPKGVTELSAEERLLHAIFGEKAREVRDTSLRVP
HGGGGIIQDVKIFTRENGDELSPGVNMMVRVYIAQKRKIQVGDKMAGRHGNKGTVSIVVPEEDMPYMPDGTPIDIMLSPM
GVPSRMNIGQVLELHLGMAARKLGIHMATPVFDGAQDTDIWEAIREAGVDSDAKSIVYDGRTGEPFDKRVAVGVMHYMKL
SHMVDDKIHARSIGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEILTYKSDDVVGRVKTYEAIVKGEPIP
KPGVPESFRVLVKELQALGLDMKVLDSEDKEIELRDMDDDDDEVVNVDALSKFKQQQDEKAADKAAKADAAKPSETTNAQ
QDNQ

Sequences:

>Translated_1204_residues
MNNLAGHLVKYGKHRTRRSYARIKEVLDLPNLIEIQTDSYQWFLDEGLREMFEDIMPIDDFAGKLSLEFVDYQLLEPKYT
VEEAREHDANYSAPLHVTLRLTNHETGEIKSQDVFFGDFPLMTEQGTFIINGAERVIVSQLVRSPGVYFNEELDKNGRPS
YGTTVIPNRGAWLELETDAKNVSYVRIDRTRKIPLTELVRALGYGSDDDIIDMLGETDSLMLTLEKDVHKNTDDSRVEES
LKDIYERLRPGEPKTADSSRSLLTARFFDPKRYDFAPVGRYKVNKKLSMKTRLMDQTLAETLADPDTGEVIAQKDTVIDK
NVMAKLSPYLERDDFKTVTYTPSDEAVVTNPMVLQVVKVYSQNDPEKVVNVIGNGNIDLKFKHIVPADIIASINYFFNLQ
EGLGSTDDIDHLGNRRIRSVGELLQNQFRIGLSRMERVVRERMSIQDAATVTPQQLINIRPVVASIKEFFGSSQLSQFMD
QTNPLGELTHKRRLSALGPGGLTRDRAGYEVRDVHYTHYGRMCPIETPEGPNIGLINSLSSYAKVNRSGFIETPYRRVDW
TTHKVTDKIDYLAADEEDQFVIAQANSPLNDDGSFVEDTVLARNKEENLETPIENVDYMDVSPKQVVAVATACIPFLEND
DSNRALMGANMQRQAVPLLDPHAPLIGTGIEYKAAHDSGIALICRHEGTVEYVDAREVRVRRDDGSLDTYKLMKFRRSNG
GKNYNQRPIVKVGDHVDNDEVLADGPAMEGGELALGQNPLVAFMTWNGYNFEDAIIINERLVREDVYTSIHIEEYESEAR
DTKLGPEEMTREIPNVGEDALKNLDEDGIIRIGAEVKDGDILVGKVTPKGVTELSAEERLLHAIFGEKAREVRDTSLRVP
HGGGGIIQDVKIFTRENGDELSPGVNMMVRVYIAQKRKIQVGDKMAGRHGNKGTVSIVVPEEDMPYMPDGTPIDIMLSPM
GVPSRMNIGQVLELHLGMAARKLGIHMATPVFDGAQDTDIWEAIREAGVDSDAKSIVYDGRTGEPFDKRVAVGVMHYMKL
SHMVDDKIHARSIGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEILTYKSDDVVGRVKTYEAIVKGEPIP
KPGVPESFRVLVKELQALGLDMKVLDSEDKEIELRDMDDDDDEVVNVDALSKFKQQQDEKAADKAAKADAAKPSETTNAQ
QDNQ
>Mature_1204_residues
MNNLAGHLVKYGKHRTRRSYARIKEVLDLPNLIEIQTDSYQWFLDEGLREMFEDIMPIDDFAGKLSLEFVDYQLLEPKYT
VEEAREHDANYSAPLHVTLRLTNHETGEIKSQDVFFGDFPLMTEQGTFIINGAERVIVSQLVRSPGVYFNEELDKNGRPS
YGTTVIPNRGAWLELETDAKNVSYVRIDRTRKIPLTELVRALGYGSDDDIIDMLGETDSLMLTLEKDVHKNTDDSRVEES
LKDIYERLRPGEPKTADSSRSLLTARFFDPKRYDFAPVGRYKVNKKLSMKTRLMDQTLAETLADPDTGEVIAQKDTVIDK
NVMAKLSPYLERDDFKTVTYTPSDEAVVTNPMVLQVVKVYSQNDPEKVVNVIGNGNIDLKFKHIVPADIIASINYFFNLQ
EGLGSTDDIDHLGNRRIRSVGELLQNQFRIGLSRMERVVRERMSIQDAATVTPQQLINIRPVVASIKEFFGSSQLSQFMD
QTNPLGELTHKRRLSALGPGGLTRDRAGYEVRDVHYTHYGRMCPIETPEGPNIGLINSLSSYAKVNRSGFIETPYRRVDW
TTHKVTDKIDYLAADEEDQFVIAQANSPLNDDGSFVEDTVLARNKEENLETPIENVDYMDVSPKQVVAVATACIPFLEND
DSNRALMGANMQRQAVPLLDPHAPLIGTGIEYKAAHDSGIALICRHEGTVEYVDAREVRVRRDDGSLDTYKLMKFRRSNG
GKNYNQRPIVKVGDHVDNDEVLADGPAMEGGELALGQNPLVAFMTWNGYNFEDAIIINERLVREDVYTSIHIEEYESEAR
DTKLGPEEMTREIPNVGEDALKNLDEDGIIRIGAEVKDGDILVGKVTPKGVTELSAEERLLHAIFGEKAREVRDTSLRVP
HGGGGIIQDVKIFTRENGDELSPGVNMMVRVYIAQKRKIQVGDKMAGRHGNKGTVSIVVPEEDMPYMPDGTPIDIMLSPM
GVPSRMNIGQVLELHLGMAARKLGIHMATPVFDGAQDTDIWEAIREAGVDSDAKSIVYDGRTGEPFDKRVAVGVMHYMKL
SHMVDDKIHARSIGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEILTYKSDDVVGRVKTYEAIVKGEPIP
KPGVPESFRVLVKELQALGLDMKVLDSEDKEIELRDMDDDDDEVVNVDALSKFKQQQDEKAADKAAKADAAKPSETTNAQ
QDNQ

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates

COG id: COG0085

COG function: function code K; DNA-directed RNA polymerase, beta subunit/140 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA polymerase beta chain family

Homologues:

Organism=Homo sapiens, GI238908505, Length=854, Percent_Identity=25.5269320843091, Blast_Score=196, Evalue=9e-50,
Organism=Homo sapiens, GI238908503, Length=854, Percent_Identity=25.5269320843091, Blast_Score=196, Evalue=1e-49,
Organism=Homo sapiens, GI4505941, Length=418, Percent_Identity=30.8612440191388, Blast_Score=185, Evalue=3e-46,
Organism=Homo sapiens, GI212286172, Length=421, Percent_Identity=29.2161520190024, Blast_Score=167, Evalue=8e-41,
Organism=Homo sapiens, GI33469941, Length=421, Percent_Identity=29.2161520190024, Blast_Score=166, Evalue=1e-40,
Organism=Escherichia coli, GI1790419, Length=963, Percent_Identity=46.6251298026999, Blast_Score=793, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17552304, Length=418, Percent_Identity=31.5789473684211, Blast_Score=186, Evalue=8e-47,
Organism=Caenorhabditis elegans, GI25144348, Length=437, Percent_Identity=29.7482837528604, Blast_Score=183, Evalue=6e-46,
Organism=Caenorhabditis elegans, GI17506623, Length=362, Percent_Identity=29.0055248618785, Blast_Score=129, Evalue=1e-29,
Organism=Saccharomyces cerevisiae, GI6324725, Length=412, Percent_Identity=30.5825242718447, Blast_Score=189, Evalue=2e-48,
Organism=Saccharomyces cerevisiae, GI6324781, Length=437, Percent_Identity=28.8329519450801, Blast_Score=168, Evalue=6e-42,
Organism=Saccharomyces cerevisiae, GI6325267, Length=359, Percent_Identity=32.3119777158774, Blast_Score=143, Evalue=2e-34,
Organism=Drosophila melanogaster, GI17647877, Length=471, Percent_Identity=29.0870488322718, Blast_Score=187, Evalue=5e-47,
Organism=Drosophila melanogaster, GI17136444, Length=359, Percent_Identity=33.1476323119777, Blast_Score=184, Evalue=2e-46,
Organism=Drosophila melanogaster, GI17136446, Length=360, Percent_Identity=30.8333333333333, Blast_Score=140, Evalue=4e-33,

Paralogues:

None

Copy number: 4233 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): RPOB_LACPL (Q88XZ3)

Other databases:

- EMBL:   AL935254
- RefSeq:   NP_784717.1
- ProteinModelPortal:   Q88XZ3
- GeneID:   1062809
- GenomeReviews:   AL935263_GR
- KEGG:   lpl:lp_1021
- NMPDR:   fig|220668.1.peg.851
- HOGENOM:   HBG285547
- OMA:   FMTWEGY
- ProtClustDB:   PRK00405
- BioCyc:   LPLA220668:LP_1021-MONOMER
- BRENDA:   2.7.7.6
- HAMAP:   MF_01321
- InterPro:   IPR010243
- InterPro:   IPR019462
- InterPro:   IPR015712
- InterPro:   IPR007120
- InterPro:   IPR007121
- InterPro:   IPR007644
- InterPro:   IPR007642
- InterPro:   IPR007645
- InterPro:   IPR007641
- InterPro:   IPR014724
- Gene3D:   G3DSA:2.40.50.150
- PANTHER:   PTHR20856
- TIGRFAMs:   TIGR02013

Pfam domain/function: PF04563 RNA_pol_Rpb2_1; PF04561 RNA_pol_Rpb2_2; PF04565 RNA_pol_Rpb2_3; PF10385 RNA_pol_Rpb2_45; PF00562 RNA_pol_Rpb2_6; PF04560 RNA_pol_Rpb2_7

EC number: =2.7.7.6

Molecular weight: Translated: 134845; Mature: 134845

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: PS01166 RNA_POL_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNLAGHLVKYGKHRTRRSYARIKEVLDLPNLIEIQTDSYQWFLDEGLREMFEDIMPIDD
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCH
FAGKLSLEFVDYQLLEPKYTVEEAREHDANYSAPLHVTLRLTNHETGEIKSQDVFFGDFP
HCCCEEEEEECEEECCCCCHHHHHHHCCCCCCCCEEEEEEEECCCCCCCCCCCEEECCCC
LMTEQGTFIINGAERVIVSQLVRSPGVYFNEELDKNGRPSYGTTVIPNRGAWLELETDAK
EEECCCCEEECCHHHHHHHHHHHCCCCEECHHCCCCCCCCCCCEECCCCCCEEEEECCCC
NVSYVRIDRTRKIPLTELVRALGYGSDDDIIDMLGETDSLMLTLEKDVHKNTDDSRVEES
CEEEEEECCCCCCCHHHHHHHHCCCCCCHHHHHHCCCCEEEEEEEHHHCCCCCHHHHHHH
LKDIYERLRPGEPKTADSSRSLLTARFFDPKRYDFAPVGRYKVNKKLSMKTRLMDQTLAE
HHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCEECCCHHHHHHHHHHHHHHH
TLADPDTGEVIAQKDTVIDKNVMAKLSPYLERDDFKTVTYTPSDEAVVTNPMVLQVVKVY
HHCCCCCCCEEECCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCEECCHHHHHHHHHH
SQNDPEKVVNVIGNGNIDLKFKHIVPADIIASINYFFNLQEGLGSTDDIDHLGNRRIRSV
CCCCHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHEEEEHHHCCCCCCHHHHCCHHHHHH
GELLQNQFRIGLSRMERVVRERMSIQDAATVTPQQLINIRPVVASIKEFFGSSQLSQFMD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHH
QTNPLGELTHKRRLSALGPGGLTRDRAGYEVRDVHYTHYGRMCPIETPEGPNIGLINSLS
CCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCHHHHHH
SYAKVNRSGFIETPYRRVDWTTHKVTDKIDYLAADEEDQFVIAQANSPLNDDGSFVEDTV
HHHHHCCCCCCCCCCHHCCCCHHHHHHHHHHEECCCCCCEEEEECCCCCCCCCCHHHHHH
LARNKEENLETPIENVDYMDVSPKQVVAVATACIPFLENDDSNRALMGANMQRQAVPLLD
HHCCCCCCCCCCHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCC
PHAPLIGTGIEYKAAHDSGIALICRHEGTVEYVDAREVRVRRDDGSLDTYKLMKFRRSNG
CCCCEEECCCEEEECCCCCEEEEEECCCCEEEECCEEEEEECCCCCCHHHHHHHHHHCCC
GKNYNQRPIVKVGDHVDNDEVLADGPAMEGGELALGQNPLVAFMTWNGYNFEDAIIINER
CCCCCCCCCEEECCCCCCCCEEECCCCCCCCCEEECCCCEEEEEEECCCCCCCEEEEHHH
LVREDVYTSIHIEEYESEARDTKLGPEEMTREIPNVGEDALKNLDEDGIIRIGAEVKDGD
HHHHHHHHEEEHHHHHHHHHHCCCCHHHHHHHCCCCCHHHHHCCCCCCEEEECCEECCCC
ILVGKVTPKGVTELSAEERLLHAIFGEKAREVRDTSLRVPHGGGGIIQDVKIFTRENGDE
EEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCEEECCCCCCCCCEEEEEEECCCCCC
LSPGVNMMVRVYIAQKRKIQVGDKMAGRHGNKGTVSIVVPEEDMPYMPDGTPIDIMLSPM
CCCCHHEEEEEEEHHCCEEECCCHHCCCCCCCCEEEEEECCCCCCCCCCCCCEEEEECCC
GVPSRMNIGQVLELHLGMAARKLGIHMATPVFDGAQDTDIWEAIREAGVDSDAKSIVYDG
CCCCCCCHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCHHHHHHHHCCCCCCCCEEEECC
RTGEPFDKRVAVGVMHYMKLSHMVDDKIHARSIGPYSLVTQQPLGGKAQFGGQRFGEMEV
CCCCCHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCHHEEECCCCCCCCCCCCCCCCCEEE
WALEAYGAAYTLQEILTYKSDDVVGRVKTYEAIVKGEPIPKPGVPESFRVLVKELQALGL
EEEECCCHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCC
DMKVLDSEDKEIELRDMDDDDDEVVNVDALSKFKQQQDEKAADKAAKADAAKPSETTNAQ
CEEEECCCCCEEEEECCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
QDNQ
CCCC
>Mature Secondary Structure
MNNLAGHLVKYGKHRTRRSYARIKEVLDLPNLIEIQTDSYQWFLDEGLREMFEDIMPIDD
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCH
FAGKLSLEFVDYQLLEPKYTVEEAREHDANYSAPLHVTLRLTNHETGEIKSQDVFFGDFP
HCCCEEEEEECEEECCCCCHHHHHHHCCCCCCCCEEEEEEEECCCCCCCCCCCEEECCCC
LMTEQGTFIINGAERVIVSQLVRSPGVYFNEELDKNGRPSYGTTVIPNRGAWLELETDAK
EEECCCCEEECCHHHHHHHHHHHCCCCEECHHCCCCCCCCCCCEECCCCCCEEEEECCCC
NVSYVRIDRTRKIPLTELVRALGYGSDDDIIDMLGETDSLMLTLEKDVHKNTDDSRVEES
CEEEEEECCCCCCCHHHHHHHHCCCCCCHHHHHHCCCCEEEEEEEHHHCCCCCHHHHHHH
LKDIYERLRPGEPKTADSSRSLLTARFFDPKRYDFAPVGRYKVNKKLSMKTRLMDQTLAE
HHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCEECCCHHHHHHHHHHHHHHH
TLADPDTGEVIAQKDTVIDKNVMAKLSPYLERDDFKTVTYTPSDEAVVTNPMVLQVVKVY
HHCCCCCCCEEECCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCEECCHHHHHHHHHH
SQNDPEKVVNVIGNGNIDLKFKHIVPADIIASINYFFNLQEGLGSTDDIDHLGNRRIRSV
CCCCHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHEEEEHHHCCCCCCHHHHCCHHHHHH
GELLQNQFRIGLSRMERVVRERMSIQDAATVTPQQLINIRPVVASIKEFFGSSQLSQFMD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHH
QTNPLGELTHKRRLSALGPGGLTRDRAGYEVRDVHYTHYGRMCPIETPEGPNIGLINSLS
CCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCHHHHHH
SYAKVNRSGFIETPYRRVDWTTHKVTDKIDYLAADEEDQFVIAQANSPLNDDGSFVEDTV
HHHHHCCCCCCCCCCHHCCCCHHHHHHHHHHEECCCCCCEEEEECCCCCCCCCCHHHHHH
LARNKEENLETPIENVDYMDVSPKQVVAVATACIPFLENDDSNRALMGANMQRQAVPLLD
HHCCCCCCCCCCHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCC
PHAPLIGTGIEYKAAHDSGIALICRHEGTVEYVDAREVRVRRDDGSLDTYKLMKFRRSNG
CCCCEEECCCEEEECCCCCEEEEEECCCCEEEECCEEEEEECCCCCCHHHHHHHHHHCCC
GKNYNQRPIVKVGDHVDNDEVLADGPAMEGGELALGQNPLVAFMTWNGYNFEDAIIINER
CCCCCCCCCEEECCCCCCCCEEECCCCCCCCCEEECCCCEEEEEEECCCCCCCEEEEHHH
LVREDVYTSIHIEEYESEARDTKLGPEEMTREIPNVGEDALKNLDEDGIIRIGAEVKDGD
HHHHHHHHEEEHHHHHHHHHHCCCCHHHHHHHCCCCCHHHHHCCCCCCEEEECCEECCCC
ILVGKVTPKGVTELSAEERLLHAIFGEKAREVRDTSLRVPHGGGGIIQDVKIFTRENGDE
EEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCEEECCCCCCCCCEEEEEEECCCCCC
LSPGVNMMVRVYIAQKRKIQVGDKMAGRHGNKGTVSIVVPEEDMPYMPDGTPIDIMLSPM
CCCCHHEEEEEEEHHCCEEECCCHHCCCCCCCCEEEEEECCCCCCCCCCCCCEEEEECCC
GVPSRMNIGQVLELHLGMAARKLGIHMATPVFDGAQDTDIWEAIREAGVDSDAKSIVYDG
CCCCCCCHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCHHHHHHHHCCCCCCCCEEEECC
RTGEPFDKRVAVGVMHYMKLSHMVDDKIHARSIGPYSLVTQQPLGGKAQFGGQRFGEMEV
CCCCCHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCHHEEECCCCCCCCCCCCCCCCCEEE
WALEAYGAAYTLQEILTYKSDDVVGRVKTYEAIVKGEPIPKPGVPESFRVLVKELQALGL
EEEECCCHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCC
DMKVLDSEDKEIELRDMDDDDDEVVNVDALSKFKQQQDEKAADKAAKADAAKPSETTNAQ
CEEEECCCCCEEEEECCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
QDNQ
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12566566