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The map label for this gene is clpC [H]

Identifier: 28377823

GI number: 28377823

Start: 936430

End: 938943

Strand: Direct

Name: clpC [H]

Synonym: lp_1019

Alternate gene names: 28377823

Gene position: 936430-938943 (Clockwise)

Preceding gene: 28377822

Following gene: 28377824

Centisome position: 28.31

GC content: 46.62

Gene sequence:

>2514_bases
ATGGATAACTTATTTACACCTAGTGCCAAAAGTGTGCTGGTACTGGCACAGGAACAGGCCAAATATTTCAAGCATCAGGC
AGTTGGTACGGAGCATTTGCTATTAGCATTGGCCATCGAAAAGAATGGAATTGCTAATAAGGTGCTACAACAATATGCCG
TTAGTGAAGATGACATTCGTGAAGAAATCGAACGGTTCACTGGCTATGGGACGTTGAGCAATGTTGGCAAGGATACCTAC
TTGCCATATTCACCAAAGGCCAAAGAAATTTTGTCCGTTGCCGGTGATGAAGCAAAACGGCTCGGTGCCAACAAGATTGG
AACGGAACATTTGTTGTTAGCGATGCTCTCTGATGAAAGTATCCTTTCCTCGCGAATTTTAATGAATTTAAACTTAGATC
TAGGTCAGACGCGTAAAGTCGTTCTTCGCAAGCTAGGTGTCAGTGACGCCATGAGTAAGCGCAAGGGTAACGCGGCTAAT
CGCGGTGGCAAGAAGACTGAAGGAACGCCAACCTTGGATTCTCTGGCGCGCGATTTGACCCAATTAGCCAGTGAACAGGA
AATGGACCCGGTAGTAGGTCGTTCCAAGGAAGTCAAACGGGTCATTCAGATTTTGTCACGGCGGACGAAGAATAATCCGG
TCTTGATTGGTGAACCAGGGGTTGGGAAGACTGCAATCGCCGAAGGTCTAGCCCAAAAGATCGTGGCCGGTGATGTGCCA
ACTGATATGGCAGATAAGCGCTTGATGATGCTCGATATGGGATCATTAGTCGCTGGGACAAAGTATCGTGGTGAATTCGA
AGACCGCCTGAAAAAAGTGATTGATGAAATTTACAACGATGGCCATGTGATCTTATTTATCGATGAATTGCATACCTTGA
TTGGTGCCGGTGGTGCTGAAGGGGCTATTGATGCTTCTAATATTCTGAAACCCGCACTTGCACGAGGGGAACTCCAAACG
ATTGGGGCAACCACTTTAAATGAATATCAAAAGTACATTGAATCTGACGCTGCGTTGGAACGGCGTTTTGCAACGGTCAT
GGTCAATGAACCGACCGAAGATGAAGCCGTTGAAATCTTAGATGGACTACGGCCACGCTATGAAGAACATCATCGGGTTA
CGATTACGGATGAAGCTGTTGATCAAGCAGTCAAGCTATCCAGCCGGTATATCAGTGATCGTTTCTTGCCTGATAAGGCC
ATTGACTTGATGGATGAGGCGGCAGCCAAAGTTCGCATCGATCAGATGGATCAACCAACGAAGTTATCCAAGAACCAGGA
CAAGTTAGCACAACTGCGTGAGGATAAAGAAACAGCGATCGAAGCACAAGATTTTGAACAGGCCGCTGATATTCGTAAGC
AGGAGATGCAACTGAAGCAACGCCTAGATCGAATCGAAGCTGACCAAGACGCTGAAGTGACTGAGGGGGCAACACCACAC
TATGATTTACAAGTCACAGGTGAGGATATTGCTCAGGTCGTTGCCGAATGGACCGGGGTTCCGTTAACGCAATTGCAAAA
ATCTGAAAGTGAACGCTTAGTTAACTTGGAAAAGATTTTGCATGAACGGGTTGTTGGACAGCCAGAAGCCGTATCCGCAG
TGGCTCGTGCTATTCGCCGTGCGCGCAGCGGGTTGAAAGATCCGAGTCGGCCAATTGGTTCCTTTATGTTCTTAGGACCA
ACTGGGGTTGGTAAGACGGAGCTAGCAAAAGCCTTGGCAGCAGCGATGTTCGGGTCTGAAGATAATATGATTCGGATCGA
CATGTCTGAATACATGGAACGCTATTCGACTAGTCGTTTGATTGGCTCGGCACCTGGTTACGTTGGTTATGACGAGGGTG
GTCAGCTGACAGAGAAGGTTCGCCAGAAACCATACTCGGTCGTGCTATTTGATGAAGTTGAAAAAGCTCATCCGGACGTT
TTTAACATTTTGTTACAAGTTTTGGATGACGGCTACTTGACGGATTCTAAGGGTCGGAAGGTAGACTTCAGAAATACGAT
TCTGATTATGACGTCGAACCTTGGGGCAACCACACTTCGTGATGAAAAATCAGTTGGTTTTGGTGCAACTGATAAGGCCA
ATGACTACAATGCGGTTGCTGCGACGATTCGAGCAACGTTAAAACAGACGTTCCGCCCAGAATTCTTAAACCGGATCGAC
GAAACAATCGTCTTCCATTCATTGAATAAGGAAGAATTACACGAAATCGTTAAGTTGATGTCACAAGAAATTGTTGATCG
AGTGGGCCAACAAGGTATCAAGATCAAAATCACTCCGGCTGCCATTGACGTGGTTGCGAAGGCTGGCTTTGACCCTGAGT
ACGGAGCACGACCAATTCGACGGGCATTACAGACTGAAATCGAAGATCGGTTGAGTGAAGAATTATTGACCGGCGCGATC
AAGGTCGATGACCAAGTTACGATTGGTGCTAGCAAGGGTACCATTACAATTAATATTAAAACCAGCCTAAGGCAGATGGT
CGTTCGACCGTTTCTTCAAAGTAGGCGCGATTAA

Upstream 100 bases:

>100_bases
ATTAACGGACCGGGACTTAGAAAACAGTCTGCGGGCCCGGATAATTATCGGAATCTTGAACCACTTGCGTTACGAAAGCT
AAAGAAAGCGAGGAATCGCA

Downstream 100 bases:

>100_bases
ATTAAAGATGACGCTTGAAGTGGTAGTCCACTTCAGGCGTCATCTTTTAGGTTCAATCGGTATTAAGATGCTACCCACTG
AAGTGAACTGTAGGATCTGA

Product: ATP-dependent Clp protease, ATP-binding subunit ClpC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 837; Mature: 837

Protein sequence:

>837_residues
MDNLFTPSAKSVLVLAQEQAKYFKHQAVGTEHLLLALAIEKNGIANKVLQQYAVSEDDIREEIERFTGYGTLSNVGKDTY
LPYSPKAKEILSVAGDEAKRLGANKIGTEHLLLAMLSDESILSSRILMNLNLDLGQTRKVVLRKLGVSDAMSKRKGNAAN
RGGKKTEGTPTLDSLARDLTQLASEQEMDPVVGRSKEVKRVIQILSRRTKNNPVLIGEPGVGKTAIAEGLAQKIVAGDVP
TDMADKRLMMLDMGSLVAGTKYRGEFEDRLKKVIDEIYNDGHVILFIDELHTLIGAGGAEGAIDASNILKPALARGELQT
IGATTLNEYQKYIESDAALERRFATVMVNEPTEDEAVEILDGLRPRYEEHHRVTITDEAVDQAVKLSSRYISDRFLPDKA
IDLMDEAAAKVRIDQMDQPTKLSKNQDKLAQLREDKETAIEAQDFEQAADIRKQEMQLKQRLDRIEADQDAEVTEGATPH
YDLQVTGEDIAQVVAEWTGVPLTQLQKSESERLVNLEKILHERVVGQPEAVSAVARAIRRARSGLKDPSRPIGSFMFLGP
TGVGKTELAKALAAAMFGSEDNMIRIDMSEYMERYSTSRLIGSAPGYVGYDEGGQLTEKVRQKPYSVVLFDEVEKAHPDV
FNILLQVLDDGYLTDSKGRKVDFRNTILIMTSNLGATTLRDEKSVGFGATDKANDYNAVAATIRATLKQTFRPEFLNRID
ETIVFHSLNKEELHEIVKLMSQEIVDRVGQQGIKIKITPAAIDVVAKAGFDPEYGARPIRRALQTEIEDRLSEELLTGAI
KVDDQVTIGASKGTITINIKTSLRQMVVRPFLQSRRD

Sequences:

>Translated_837_residues
MDNLFTPSAKSVLVLAQEQAKYFKHQAVGTEHLLLALAIEKNGIANKVLQQYAVSEDDIREEIERFTGYGTLSNVGKDTY
LPYSPKAKEILSVAGDEAKRLGANKIGTEHLLLAMLSDESILSSRILMNLNLDLGQTRKVVLRKLGVSDAMSKRKGNAAN
RGGKKTEGTPTLDSLARDLTQLASEQEMDPVVGRSKEVKRVIQILSRRTKNNPVLIGEPGVGKTAIAEGLAQKIVAGDVP
TDMADKRLMMLDMGSLVAGTKYRGEFEDRLKKVIDEIYNDGHVILFIDELHTLIGAGGAEGAIDASNILKPALARGELQT
IGATTLNEYQKYIESDAALERRFATVMVNEPTEDEAVEILDGLRPRYEEHHRVTITDEAVDQAVKLSSRYISDRFLPDKA
IDLMDEAAAKVRIDQMDQPTKLSKNQDKLAQLREDKETAIEAQDFEQAADIRKQEMQLKQRLDRIEADQDAEVTEGATPH
YDLQVTGEDIAQVVAEWTGVPLTQLQKSESERLVNLEKILHERVVGQPEAVSAVARAIRRARSGLKDPSRPIGSFMFLGP
TGVGKTELAKALAAAMFGSEDNMIRIDMSEYMERYSTSRLIGSAPGYVGYDEGGQLTEKVRQKPYSVVLFDEVEKAHPDV
FNILLQVLDDGYLTDSKGRKVDFRNTILIMTSNLGATTLRDEKSVGFGATDKANDYNAVAATIRATLKQTFRPEFLNRID
ETIVFHSLNKEELHEIVKLMSQEIVDRVGQQGIKIKITPAAIDVVAKAGFDPEYGARPIRRALQTEIEDRLSEELLTGAI
KVDDQVTIGASKGTITINIKTSLRQMVVRPFLQSRRD
>Mature_837_residues
MDNLFTPSAKSVLVLAQEQAKYFKHQAVGTEHLLLALAIEKNGIANKVLQQYAVSEDDIREEIERFTGYGTLSNVGKDTY
LPYSPKAKEILSVAGDEAKRLGANKIGTEHLLLAMLSDESILSSRILMNLNLDLGQTRKVVLRKLGVSDAMSKRKGNAAN
RGGKKTEGTPTLDSLARDLTQLASEQEMDPVVGRSKEVKRVIQILSRRTKNNPVLIGEPGVGKTAIAEGLAQKIVAGDVP
TDMADKRLMMLDMGSLVAGTKYRGEFEDRLKKVIDEIYNDGHVILFIDELHTLIGAGGAEGAIDASNILKPALARGELQT
IGATTLNEYQKYIESDAALERRFATVMVNEPTEDEAVEILDGLRPRYEEHHRVTITDEAVDQAVKLSSRYISDRFLPDKA
IDLMDEAAAKVRIDQMDQPTKLSKNQDKLAQLREDKETAIEAQDFEQAADIRKQEMQLKQRLDRIEADQDAEVTEGATPH
YDLQVTGEDIAQVVAEWTGVPLTQLQKSESERLVNLEKILHERVVGQPEAVSAVARAIRRARSGLKDPSRPIGSFMFLGP
TGVGKTELAKALAAAMFGSEDNMIRIDMSEYMERYSTSRLIGSAPGYVGYDEGGQLTEKVRQKPYSVVLFDEVEKAHPDV
FNILLQVLDDGYLTDSKGRKVDFRNTILIMTSNLGATTLRDEKSVGFGATDKANDYNAVAATIRATLKQTFRPEFLNRID
ETIVFHSLNKEELHEIVKLMSQEIVDRVGQQGIKIKITPAAIDVVAKAGFDPEYGARPIRRALQTEIEDRLSEELLTGAI
KVDDQVTIGASKGTITINIKTSLRQMVVRPFLQSRRD

Specific function: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 UVR domain [H]

Homologues:

Organism=Homo sapiens, GI13540606, Length=345, Percent_Identity=37.6811594202899, Blast_Score=199, Evalue=1e-50,
Organism=Escherichia coli, GI1788943, Length=857, Percent_Identity=43.5239206534422, Blast_Score=680, Evalue=0.0,
Organism=Escherichia coli, GI1787109, Length=417, Percent_Identity=41.0071942446043, Blast_Score=288, Evalue=9e-79,
Organism=Saccharomyces cerevisiae, GI6320464, Length=699, Percent_Identity=46.6380543633763, Blast_Score=589, Evalue=1e-169,
Organism=Saccharomyces cerevisiae, GI6323002, Length=778, Percent_Identity=39.4601542416452, Blast_Score=519, Evalue=1e-148,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR018368
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR004176
- InterPro:   IPR023150
- InterPro:   IPR001943 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small; PF02151 UVR [H]

EC number: NA

Molecular weight: Translated: 92644; Mature: 92644

Theoretical pI: Translated: 5.28; Mature: 5.28

Prosite motif: PS50151 UVR ; PS00870 CLPAB_1 ; PS00871 CLPAB_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDNLFTPSAKSVLVLAQEQAKYFKHQAVGTEHLLLALAIEKNGIANKVLQQYAVSEDDIR
CCCCCCCCCCCEEEEEHHHHHHHHHHHCCHHHEEEEEEECCCCHHHHHHHHHCCCHHHHH
EEIERFTGYGTLSNVGKDTYLPYSPKAKEILSVAGDEAKRLGANKIGTEHLLLAMLSDES
HHHHHHCCCCCHHHCCCCCCCCCCCCHHHHHHHCCHHHHHCCCCCCCHHHHHHHHHCCHH
ILSSRILMNLNLDLGQTRKVVLRKLGVSDAMSKRKGNAANRGGKKTEGTPTLDSLARDLT
HHHHHHHEEECCCCCHHHHHHHHHHCHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHH
QLASEQEMDPVVGRSKEVKRVIQILSRRTKNNPVLIGEPGVGKTAIAEGLAQKIVAGDVP
HHHHHCCCCHHCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCC
TDMADKRLMMLDMGSLVAGTKYRGEFEDRLKKVIDEIYNDGHVILFIDELHTLIGAGGAE
CCHHCCEEHEEECCHHHCCCCCCCCHHHHHHHHHHHHHCCCCEEEEHHHHHHHHCCCCCC
GAIDASNILKPALARGELQTIGATTLNEYQKYIESDAALERRFATVMVNEPTEDEAVEIL
CCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHH
DGLRPRYEEHHRVTITDEAVDQAVKLSSRYISDRFLPDKAIDLMDEAAAKVRIDQMDQPT
HCCCCCHHCCCEEEEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHEEHHCCCCCC
KLSKNQDKLAQLREDKETAIEAQDFEQAADIRKQEMQLKQRLDRIEADQDAEVTEGATPH
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
YDLQVTGEDIAQVVAEWTGVPLTQLQKSESERLVNLEKILHERVVGQPEAVSAVARAIRR
EEEEECHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
ARSGLKDPSRPIGSFMFLGPTGVGKTELAKALAAAMFGSEDNMIRIDMSEYMERYSTSRL
HHCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHH
IGSAPGYVGYDEGGQLTEKVRQKPYSVVLFDEVEKAHPDVFNILLQVLDDGYLTDSKGRK
HCCCCCCCCCCCCCHHHHHHHHCCCEEEEEHHHHHHCCHHHHHHHHHHCCCCEECCCCCE
VDFRNTILIMTSNLGATTLRDEKSVGFGATDKANDYNAVAATIRATLKQTFRPEFLNRID
EECCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHH
ETIVFHSLNKEELHEIVKLMSQEIVDRVGQQGIKIKITPAAIDVVAKAGFDPEYGARPIR
HHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHCCCCCCCCCHHHH
RALQTEIEDRLSEELLTGAIKVDDQVTIGASKGTITINIKTSLRQMVVRPFLQSRRD
HHHHHHHHHHHHHHHHHHHEEECCEEEEECCCCEEEEEEHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDNLFTPSAKSVLVLAQEQAKYFKHQAVGTEHLLLALAIEKNGIANKVLQQYAVSEDDIR
CCCCCCCCCCCEEEEEHHHHHHHHHHHCCHHHEEEEEEECCCCHHHHHHHHHCCCHHHHH
EEIERFTGYGTLSNVGKDTYLPYSPKAKEILSVAGDEAKRLGANKIGTEHLLLAMLSDES
HHHHHHCCCCCHHHCCCCCCCCCCCCHHHHHHHCCHHHHHCCCCCCCHHHHHHHHHCCHH
ILSSRILMNLNLDLGQTRKVVLRKLGVSDAMSKRKGNAANRGGKKTEGTPTLDSLARDLT
HHHHHHHEEECCCCCHHHHHHHHHHCHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHH
QLASEQEMDPVVGRSKEVKRVIQILSRRTKNNPVLIGEPGVGKTAIAEGLAQKIVAGDVP
HHHHHCCCCHHCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCC
TDMADKRLMMLDMGSLVAGTKYRGEFEDRLKKVIDEIYNDGHVILFIDELHTLIGAGGAE
CCHHCCEEHEEECCHHHCCCCCCCCHHHHHHHHHHHHHCCCCEEEEHHHHHHHHCCCCCC
GAIDASNILKPALARGELQTIGATTLNEYQKYIESDAALERRFATVMVNEPTEDEAVEIL
CCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHH
DGLRPRYEEHHRVTITDEAVDQAVKLSSRYISDRFLPDKAIDLMDEAAAKVRIDQMDQPT
HCCCCCHHCCCEEEEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHEEHHCCCCCC
KLSKNQDKLAQLREDKETAIEAQDFEQAADIRKQEMQLKQRLDRIEADQDAEVTEGATPH
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
YDLQVTGEDIAQVVAEWTGVPLTQLQKSESERLVNLEKILHERVVGQPEAVSAVARAIRR
EEEEECHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
ARSGLKDPSRPIGSFMFLGPTGVGKTELAKALAAAMFGSEDNMIRIDMSEYMERYSTSRL
HHCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHH
IGSAPGYVGYDEGGQLTEKVRQKPYSVVLFDEVEKAHPDVFNILLQVLDDGYLTDSKGRK
HCCCCCCCCCCCCCHHHHHHHHCCCEEEEEHHHHHHCCHHHHHHHHHHCCCCEECCCCCE
VDFRNTILIMTSNLGATTLRDEKSVGFGATDKANDYNAVAATIRATLKQTFRPEFLNRID
EECCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHH
ETIVFHSLNKEELHEIVKLMSQEIVDRVGQQGIKIKITPAAIDVVAKAGFDPEYGARPIR
HHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHCCCCCCCCCHHHH
RALQTEIEDRLSEELLTGAIKVDDQVTIGASKGTITINIKTSLRQMVVRPFLQSRRD
HHHHHHHHHHHHHHHHHHHEEECCEEEEECCCCEEEEEEHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12235376 [H]