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The map label for this gene is yabR [H]

Identifier: 28377428

GI number: 28377428

Start: 493572

End: 494111

Strand: Direct

Name: yabR [H]

Synonym: lp_0543

Alternate gene names: 28377428

Gene position: 493572-494111 (Clockwise)

Preceding gene: 28377427

Following gene: 28377429

Centisome position: 14.92

GC content: 45.19

Gene sequence:

>540_bases
ATGGCAATTGAAGTAGGTACAAAAGTCACTGGTAAGGTATCTGGGATTACTAATTTTGGTGCATTTGTAAACTTGGGTAA
TAATCAAACGGGGCTAGTACACATCAGTGAGGTTTCCGATGGCTTTGTAAAGGACATTCATGATGTCTTGAGCGTGGGCG
ACGATGTTACAGTCAAAGTGTTATCCGTTGGTGATGACGGTAAGATTGGCTTGTCAATCCGTAAAGCGGTTGACAAACCT
CAAGGTGAACATGAACATCATGGCAACCATCAGGGTGGCAACCGGCCAAACAATCATCAAGGTAACAACCATGGTCATGG
TGAACGTCAAACCAATGGCAATCATCACGATCGGTCAAATAATTTCCATAGTCGTGGGGGAAATGGCGGCGGTCGTTACC
AATCACGACAACATGAACCTAAGAAGCAGGACTTTGATTCATTGATGTCTGGCTTCTTAAAAGATAGCGAGGATCGGCTA
GCAACCTTAAAGCGTAATACTGAAGGTAAGCGTGGTGGCCGTGGTGGTCGTCGTAGCTAA

Upstream 100 bases:

>100_bases
GAGTAGACCACTTTTTATTAATTGCTTAAATGTATAACTCAACGTTTCACAAAGTATGCTATACTAAAACCATTATTTCA
TAGGAGGAACAACTTTTTTT

Downstream 100 bases:

>100_bases
ACTTAGTGACTTGCCATTAATCTAGTTAAATTTTGAAGCACGGTGCGGCTATTTAGAGTCACGACCGTGCTTTTTTTATT
GAAAATTGCCGATTGTTCAA

Product: hypothetical protein

Products: RNAn; a nucleoside diphosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 179; Mature: 178

Protein sequence:

>179_residues
MAIEVGTKVTGKVSGITNFGAFVNLGNNQTGLVHISEVSDGFVKDIHDVLSVGDDVTVKVLSVGDDGKIGLSIRKAVDKP
QGEHEHHGNHQGGNRPNNHQGNNHGHGERQTNGNHHDRSNNFHSRGGNGGGRYQSRQHEPKKQDFDSLMSGFLKDSEDRL
ATLKRNTEGKRGGRGGRRS

Sequences:

>Translated_179_residues
MAIEVGTKVTGKVSGITNFGAFVNLGNNQTGLVHISEVSDGFVKDIHDVLSVGDDVTVKVLSVGDDGKIGLSIRKAVDKP
QGEHEHHGNHQGGNRPNNHQGNNHGHGERQTNGNHHDRSNNFHSRGGNGGGRYQSRQHEPKKQDFDSLMSGFLKDSEDRL
ATLKRNTEGKRGGRGGRRS
>Mature_178_residues
AIEVGTKVTGKVSGITNFGAFVNLGNNQTGLVHISEVSDGFVKDIHDVLSVGDDVTVKVLSVGDDGKIGLSIRKAVDKPQ
GEHEHHGNHQGGNRPNNHQGNNHGHGERQTNGNHHDRSNNFHSRGGNGGGRYQSRQHEPKKQDFDSLMSGFLKDSEDRLA
TLKRNTEGKRGGRGGRRS

Specific function: Involved In Mrna Degradation. Hydrolyzes Single-Stranded Polyribonucleotides Processively In The 3' To 5' Direction. Involved In The RNA Degradosome, A Multi-Enzyme Complex Important In RNA Processing And Messenger RNA Degradation. [C]

COG id: COG1098

COG function: function code J; Predicted RNA binding protein (contains ribosomal protein S1 domain)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1 motif domain [H]

Homologues:

Organism=Escherichia coli, GI145693187, Length=79, Percent_Identity=49.3670886075949, Blast_Score=75, Evalue=2e-15,
Organism=Escherichia coli, GI87082262, Length=115, Percent_Identity=42.6086956521739, Blast_Score=72, Evalue=3e-14,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1000 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 3328 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR003029
- InterPro:   IPR022967 [H]

Pfam domain/function: PF00575 S1 [H]

EC number: 2.7.7.8 [C]

Molecular weight: Translated: 19371; Mature: 19240

Theoretical pI: Translated: 10.20; Mature: 10.20

Prosite motif: PS50126 S1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIEVGTKVTGKVSGITNFGAFVNLGNNQTGLVHISEVSDGFVKDIHDVLSVGDDVTVKV
CEEECCCCCCCEECCCCCCCEEEECCCCCCEEEEECCCCCHHHHHHHHHHHCCCCEEEEE
LSVGDDGKIGLSIRKAVDKPQGEHEHHGNHQGGNRPNNHQGNNHGHGERQTNGNHHDRSN
EEECCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
NFHSRGGNGGGRYQSRQHEPKKQDFDSLMSGFLKDSEDRLATLKRNTEGKRGGRGGRRS
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
AIEVGTKVTGKVSGITNFGAFVNLGNNQTGLVHISEVSDGFVKDIHDVLSVGDDVTVKV
EEECCCCCCCEECCCCCCCEEEECCCCCCEEEEECCCCCHHHHHHHHHHHCCCCEEEEE
LSVGDDGKIGLSIRKAVDKPQGEHEHHGNHQGGNRPNNHQGNNHGHGERQTNGNHHDRSN
EEECCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
NFHSRGGNGGGRYQSRQHEPKKQDFDSLMSGFLKDSEDRLATLKRNTEGKRGGRGGRRS
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): 4500 [C]

Specific activity: NA

Km value (mM): NA

Substrates: RNAn+1; phosphate [C]

Specific reaction: RNAn+1 + phosphate = RNAn + a nucleoside diphosphate [C]

General reaction: Nucleotidyl group transfer [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8113187; 7584024; 9384377 [H]