BacMap

Definition	Lactobacillus plantarum WCFS1, complete genome.
Accession	NC_004567
Length	3,308,274

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The map label for this gene is yvaG [H]

Identifier: 28377100

GI number: 28377100

Start: 135873

End: 136667

Strand: Direct

Name: yvaG [H]

Synonym: lp_0159

Alternate gene names: 28377100

Gene position: 135873-136667 (Clockwise)

Preceding gene: 28377099

Following gene: 28377101

Centisome position: 4.11

GC content: 46.92

Gene sequence:

>795_bases
ATGGAAATGGGATTGGCAGGAAAACGGGTCTTGGTCACTGGTTCGACTAAGGGAATCGGACGGGCAATTGCGGTAGCATT
TGCCAAGGAAGGCGCGGATGTGGTCATTAATGGTCGCCGCGCAGATACGGTGGCAGCGGTTGTGGATGAACTCGCAGCGG
CATACCCAACAACTCATCCAGTGGCGGCACCGTATGATATTAGTGATCCGCAGCAAGCTGACAAAATGTTTCAACAAATT
CCAACGGTTGACGTACTGGTCAACAATATGGGAATCTTTGGGCCAATGGCTTACGATGAGATTGACGATGCAACCTGGGA
ACGCTTCTTTAAAGTGAACGTGTTGTCTGGCAATCGGTTGGCAAAACATTATTTACCTGCAATGTTAGCCCAAGATTTTG
GACGCATTATCTTTATTGCGAGTGAAGAAGCAGTTATGCCTTCGGGGGAAATGCCCCAATATTCGATGACTAAATCGATG
AACCTTTCTTTAGCGAAGAGTCTGTCGAAGTTAACAGTTGGCAGCCACGTAACGGTTAACACGGTTATGCCCGGCTCGAC
ATTAACAGAAGGTGTTCAGAAAATGTTAGATGATATGTATGCTGATTCAGATTTGCCAAAGGATCAGTGGGAGCATGACT
TTATGATTAATCATCGACCACTATCACAAATTCAGCGTTTGATTCGGCCGGAAGAAATTGGTCGGTTAGCAGTGTTTGTC
GCTAGTCCGTTTGCTAGCAGTTTTTCGGGTGAAGCATTGCGGGCGGATGGTGGGTTAGTCCCAACTATCTTCTAG

Upstream 100 bases:

>100_bases
CGAGTTAGATTAATACCCGTGAGGACCGATTATTTGTGTTTATTGATCGAACTAGCTAAAATTAACAGGCAATTTAAATT
AGAACGGAGGAACTTTGAGC

Downstream 100 bases:

>100_bases
TGGCTAATGAAGACGATATATCTTTCTGGTTCTGCCATAGAAATTCAGATGTCAAAAAACTGTTTTAGCGAGTAAAGTTT
ATCGCCAAAACAGTTTTTTT

Product: short-chain dehydrogenase/oxidoreductase

Products: 3-oxoacyl-[acyl-carrier protein]; NADPH; H+

Alternate protein names: NA

Number of amino acids: Translated: 264; Mature: 264

Protein sequence:

>264_residues
MEMGLAGKRVLVTGSTKGIGRAIAVAFAKEGADVVINGRRADTVAAVVDELAAAYPTTHPVAAPYDISDPQQADKMFQQI
PTVDVLVNNMGIFGPMAYDEIDDATWERFFKVNVLSGNRLAKHYLPAMLAQDFGRIIFIASEEAVMPSGEMPQYSMTKSM
NLSLAKSLSKLTVGSHVTVNTVMPGSTLTEGVQKMLDDMYADSDLPKDQWEHDFMINHRPLSQIQRLIRPEEIGRLAVFV
ASPFASSFSGEALRADGGLVPTIF

Sequences:

>Translated_264_residues
MEMGLAGKRVLVTGSTKGIGRAIAVAFAKEGADVVINGRRADTVAAVVDELAAAYPTTHPVAAPYDISDPQQADKMFQQI
PTVDVLVNNMGIFGPMAYDEIDDATWERFFKVNVLSGNRLAKHYLPAMLAQDFGRIIFIASEEAVMPSGEMPQYSMTKSM
NLSLAKSLSKLTVGSHVTVNTVMPGSTLTEGVQKMLDDMYADSDLPKDQWEHDFMINHRPLSQIQRLIRPEEIGRLAVFV
ASPFASSFSGEALRADGGLVPTIF
>Mature_264_residues
MEMGLAGKRVLVTGSTKGIGRAIAVAFAKEGADVVINGRRADTVAAVVDELAAAYPTTHPVAAPYDISDPQQADKMFQQI
PTVDVLVNNMGIFGPMAYDEIDDATWERFFKVNVLSGNRLAKHYLPAMLAQDFGRIIFIASEEAVMPSGEMPQYSMTKSM
NLSLAKSLSKLTVGSHVTVNTVMPGSTLTEGVQKMLDDMYADSDLPKDQWEHDFMINHRPLSQIQRLIRPEEIGRLAVFV
ASPFASSFSGEALRADGGLVPTIF

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI5031737, Length=257, Percent_Identity=27.6264591439689, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI4504505, Length=196, Percent_Identity=31.1224489795918, Blast_Score=78, Evalue=7e-15,
Organism=Homo sapiens, GI32483357, Length=262, Percent_Identity=28.2442748091603, Blast_Score=78, Evalue=8e-15,
Organism=Homo sapiens, GI66933014, Length=255, Percent_Identity=28.2352941176471, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI7705925, Length=262, Percent_Identity=27.0992366412214, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI31542939, Length=207, Percent_Identity=28.0193236714976, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI19923817, Length=268, Percent_Identity=23.5074626865672, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI40807363, Length=167, Percent_Identity=26.9461077844311, Blast_Score=68, Evalue=9e-12,
Organism=Homo sapiens, GI33667109, Length=185, Percent_Identity=29.1891891891892, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI4503817, Length=243, Percent_Identity=23.8683127572016, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1787335, Length=263, Percent_Identity=30.4182509505703, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1787905, Length=260, Percent_Identity=31.5384615384615, Blast_Score=100, Evalue=8e-23,
Organism=Escherichia coli, GI1786812, Length=272, Percent_Identity=30.8823529411765, Blast_Score=94, Evalue=7e-21,
Organism=Escherichia coli, GI1790717, Length=263, Percent_Identity=25.4752851711027, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI87082100, Length=260, Percent_Identity=28.4615384615385, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI87082160, Length=264, Percent_Identity=27.6515151515151, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1789378, Length=197, Percent_Identity=30.4568527918782, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1787820, Length=183, Percent_Identity=27.8688524590164, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1788459, Length=268, Percent_Identity=28.3582089552239, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI2367365, Length=257, Percent_Identity=27.2373540856031, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1789208, Length=265, Percent_Identity=23.0188679245283, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1789057, Length=259, Percent_Identity=25.4826254826255, Blast_Score=61, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI17560676, Length=264, Percent_Identity=29.9242424242424, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17561402, Length=264, Percent_Identity=29.5454545454545, Blast_Score=91, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI17562990, Length=270, Percent_Identity=28.8888888888889, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17562906, Length=275, Percent_Identity=28.3636363636364, Blast_Score=84, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17568967, Length=223, Percent_Identity=29.1479820627803, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI115534694, Length=259, Percent_Identity=28.1853281853282, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17562908, Length=272, Percent_Identity=27.9411764705882, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI72000259, Length=267, Percent_Identity=29.9625468164794, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17562904, Length=279, Percent_Identity=26.8817204301075, Blast_Score=77, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI17560150, Length=267, Percent_Identity=27.7153558052434, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI193204405, Length=271, Percent_Identity=29.1512915129151, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17562910, Length=269, Percent_Identity=26.7657992565056, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17531453, Length=273, Percent_Identity=27.8388278388278, Blast_Score=74, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI17551412, Length=265, Percent_Identity=29.0566037735849, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17563726, Length=276, Percent_Identity=28.6231884057971, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17538480, Length=265, Percent_Identity=27.5471698113208, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17508895, Length=170, Percent_Identity=32.9411764705882, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI71994604, Length=264, Percent_Identity=26.8939393939394, Blast_Score=70, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17560332, Length=267, Percent_Identity=27.7153558052434, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17544670, Length=196, Percent_Identity=28.5714285714286, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17564282, Length=141, Percent_Identity=34.0425531914894, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17555706, Length=269, Percent_Identity=27.1375464684015, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI71994600, Length=258, Percent_Identity=26.3565891472868, Blast_Score=66, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17559104, Length=267, Percent_Identity=25.4681647940075, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17560220, Length=272, Percent_Identity=26.8382352941176, Blast_Score=64, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=198, Percent_Identity=29.7979797979798, Blast_Score=77, Evalue=2e-15,
Organism=Drosophila melanogaster, GI21355319, Length=269, Percent_Identity=28.6245353159851, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24639444, Length=269, Percent_Identity=29.7397769516729, Blast_Score=84, Evalue=8e-17,
Organism=Drosophila melanogaster, GI24644339, Length=260, Percent_Identity=26.1538461538462, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24643142, Length=258, Percent_Identity=27.1317829457364, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI161076933, Length=191, Percent_Identity=27.7486910994764, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24584748, Length=191, Percent_Identity=27.7486910994764, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI23397609, Length=263, Percent_Identity=26.615969581749, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI21358495, Length=197, Percent_Identity=28.9340101522843, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24584744, Length=190, Percent_Identity=28.4210526315789, Blast_Score=71, Evalue=7e-13,
Organism=Drosophila melanogaster, GI28574402, Length=191, Percent_Identity=28.7958115183246, Blast_Score=71, Evalue=8e-13,
Organism=Drosophila melanogaster, GI18859837, Length=199, Percent_Identity=28.1407035175879, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24581726, Length=169, Percent_Identity=28.9940828402367, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.1.1.100

Molecular weight: Translated: 28712; Mature: 28712

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.3 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEMGLAGKRVLVTGSTKGIGRAIAVAFAKEGADVVINGRRADTVAAVVDELAAAYPTTHP
CCCCCCCCEEEEECCCCCHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHCCCCCC
VAAPYDISDPQQADKMFQQIPTVDVLVNNMGIFGPMAYDEIDDATWERFFKVNVLSGNRL
CCCCCCCCCHHHHHHHHHHCCHHHHHHHCCCCCCCCCHHHHCHHHHHHEEEEEEECCCHH
AKHYLPAMLAQDFGRIIFIASEEAVMPSGEMPQYSMTKSMNLSLAKSLSKLTVGSHVTVN
HHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHCCCCEEEE
TVMPGSTLTEGVQKMLDDMYADSDLPKDQWEHDFMINHRPLSQIQRLIRPEEIGRLAVFV
EECCCHHHHHHHHHHHHHHHCCCCCCHHHCCCCEEECCCCHHHHHHHHCHHHHCEEEEEE
ASPFASSFSGEALRADGGLVPTIF
ECCCCCCCCCCEEECCCCCCCCCC
>Mature Secondary Structure
MEMGLAGKRVLVTGSTKGIGRAIAVAFAKEGADVVINGRRADTVAAVVDELAAAYPTTHP
CCCCCCCCEEEEECCCCCHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHCCCCCC
VAAPYDISDPQQADKMFQQIPTVDVLVNNMGIFGPMAYDEIDDATWERFFKVNVLSGNRL
CCCCCCCCCHHHHHHHHHHCCHHHHHHHCCCCCCCCCHHHHCHHHHHHEEEEEEECCCHH
AKHYLPAMLAQDFGRIIFIASEEAVMPSGEMPQYSMTKSMNLSLAKSLSKLTVGSHVTVN
HHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHCCCCEEEE
TVMPGSTLTEGVQKMLDDMYADSDLPKDQWEHDFMINHRPLSQIQRLIRPEEIGRLAVFV
EECCCHHHHHHHHHHHHHHHCCCCCCHHHCCCCEEECCCCHHHHHHHHCHHHHCEEEEEE
ASPFASSFSGEALRADGGLVPTIF
ECCCCCCCCCCEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NADPH [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (3R)-3-hydroxyacyl-[acyl-carrier protein]; NADP+

Specific reaction: (3R)-3-hydroxyacyl-[acyl-carrier protein] + NADP+ = 3-oxoacyl-[acyl-carrier protein] + NADPH + H+

General reaction: Redox reaction [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]