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The map label for this gene is dapB

Identifier: 28211892

GI number: 28211892

Start: 2420793

End: 2421560

Strand: Direct

Name: dapB

Synonym: CTC02295

Alternate gene names: 28211892

Gene position: 2420793-2421560 (Clockwise)

Preceding gene: 28211891

Following gene: 28211896

Centisome position: 86.48

GC content: 29.3

Gene sequence:

>768_bases
GTGGAGGTATATTTAATGGTTAGAATAATGTTAGTTGGTTGCAATGGTAAAATGGGTAGAATAATAACTCATTGTTCTAA
GGATTTTAATGATATTGAAATAGTAGCTGGTGTGGATAAAAGCTCAACTTCTAACTTAGATTTCCCAGTATTTGAAAATA
TACATTCTTCTAGTGTGGAATGCGATGTGGTTTTAGATTTTTCTAGACCATCTTCTTTAAAAAGTTTAATTAGTTATTGT
ACAGAAAAAAAATTACCTCTAGTTTTATGTACTACTGGATATTCAAAAGAAGAATTAAATTTAATAGAGGAGACATCTAA
AAATATCCCTATATTTAAATCAGCTAATATGTCCATAGGGATAAATGTAATAAACTCTCTTTTAAAAGATATTAGTAAAA
AACTTTATAAAGACTTTGATATAGAAATAATAGAAAAACATCATAATCAAAAAGTAGATTCACCTAGTGGTACTGCTTTA
CTTTTAGCAGATACAATTAAGGATAATGTACCAGAAAAATTAGAATATATCTATGGAAGATCAGGACATTCAAAAAGAAC
TAAGAACGAAATAGGTATTCATGCTATAAGGGGTGGTTCTATAGTAGGTGATCATGATGTGATTTTTGCAGGTATTGGAG
AATGTATAGAAATTAAGCATACCGCTATATCTAGAGAAGTTTTTGCCATAGGAGCATTAAAGGCTTCCGCTTTTATGAAA
GGTAAACCTTCAGGTATGTACAATATGGATTGTATGTTGAACTCTTAA

Upstream 100 bases:

>100_bases
AACTAAGGCTTCCGCTATGTAATATGGATGAAAGTAATTTAAACCTATTAAAAAAAGAGCTATCAAATCATGCTCTTATT
AAGTAATAAACTATATTGAT

Downstream 100 bases:

>100_bases
TAATTATATAAAAGCCCTCAAAATGAGGGCTTTTATTATGTTCATTTTATTCATCTTCATTTTCCTTAACTTCATTTTCT
ACTTTTTCCATTTTTGATAT

Product: dihydrodipicolinate reductase

Products: NA

Alternate protein names: DHPR

Number of amino acids: Translated: 255; Mature: 255

Protein sequence:

>255_residues
MEVYLMVRIMLVGCNGKMGRIITHCSKDFNDIEIVAGVDKSSTSNLDFPVFENIHSSSVECDVVLDFSRPSSLKSLISYC
TEKKLPLVLCTTGYSKEELNLIEETSKNIPIFKSANMSIGINVINSLLKDISKKLYKDFDIEIIEKHHNQKVDSPSGTAL
LLADTIKDNVPEKLEYIYGRSGHSKRTKNEIGIHAIRGGSIVGDHDVIFAGIGECIEIKHTAISREVFAIGALKASAFMK
GKPSGMYNMDCMLNS

Sequences:

>Translated_255_residues
MEVYLMVRIMLVGCNGKMGRIITHCSKDFNDIEIVAGVDKSSTSNLDFPVFENIHSSSVECDVVLDFSRPSSLKSLISYC
TEKKLPLVLCTTGYSKEELNLIEETSKNIPIFKSANMSIGINVINSLLKDISKKLYKDFDIEIIEKHHNQKVDSPSGTAL
LLADTIKDNVPEKLEYIYGRSGHSKRTKNEIGIHAIRGGSIVGDHDVIFAGIGECIEIKHTAISREVFAIGALKASAFMK
GKPSGMYNMDCMLNS
>Mature_255_residues
MEVYLMVRIMLVGCNGKMGRIITHCSKDFNDIEIVAGVDKSSTSNLDFPVFENIHSSSVECDVVLDFSRPSSLKSLISYC
TEKKLPLVLCTTGYSKEELNLIEETSKNIPIFKSANMSIGINVINSLLKDISKKLYKDFDIEIIEKHHNQKVDSPSGTAL
LLADTIKDNVPEKLEYIYGRSGHSKRTKNEIGIHAIRGGSIVGDHDVIFAGIGECIEIKHTAISREVFAIGALKASAFMK
GKPSGMYNMDCMLNS

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; second step. [C]

COG id: COG0289

COG function: function code E; Dihydrodipicolinate reductase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydrodipicolinate reductase family

Homologues:

Organism=Escherichia coli, GI1786214, Length=264, Percent_Identity=33.3333333333333, Blast_Score=152, Evalue=3e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DAPB_CLOTE (Q891S2)

Other databases:

- EMBL:   AE015927
- RefSeq:   NP_782836.1
- ProteinModelPortal:   Q891S2
- SMR:   Q891S2
- GeneID:   1060445
- GenomeReviews:   AE015927_GR
- KEGG:   ctc:CTC02295
- NMPDR:   fig|212717.1.peg.2058
- HOGENOM:   HBG594002
- OMA:   GALKACE
- PhylomeDB:   Q891S2
- ProtClustDB:   PRK00048
- BioCyc:   CTET212717:CTC_02295-MONOMER
- BRENDA:   1.3.1.26
- GO:   GO:0005737
- GO:   GO:0005488
- HAMAP:   MF_00102
- InterPro:   IPR022663
- InterPro:   IPR000846
- InterPro:   IPR022664
- InterPro:   IPR011770
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- PANTHER:   PTHR20836
- TIGRFAMs:   TIGR00036

Pfam domain/function: PF05173 DapB_C; PF01113 DapB_N

EC number: =1.3.1.26

Molecular weight: Translated: 28155; Mature: 28155

Theoretical pI: Translated: 6.93; Mature: 6.93

Prosite motif: PS01298 DAPB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEVYLMVRIMLVGCNGKMGRIITHCSKDFNDIEIVAGVDKSSTSNLDFPVFENIHSSSVE
CEEEEEEEEEEECCCCCHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCHHHHCCCCCCCE
CDVVLDFSRPSSLKSLISYCTEKKLPLVLCTTGYSKEELNLIEETSKNIPIFKSANMSIG
EEEEEECCCCHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHCCCCCCEEECCCCEEC
INVINSLLKDISKKLYKDFDIEIIEKHHNQKVDSPSGTALLLADTIKDNVPEKLEYIYGR
HHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCEEEEEECHHCCCHHHHHHHHCC
SGHSKRTKNEIGIHAIRGGSIVGDHDVIFAGIGECIEIKHTAISREVFAIGALKASAFMK
CCCCCCCCCCCCEEEEECCCEECCCCEEEECCCCHHHHHHHHHHHHHHEEEHHHHHHHCC
GKPSGMYNMDCMLNS
CCCCCEEEEEEEECC
>Mature Secondary Structure
MEVYLMVRIMLVGCNGKMGRIITHCSKDFNDIEIVAGVDKSSTSNLDFPVFENIHSSSVE
CEEEEEEEEEEECCCCCHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCHHHHCCCCCCCE
CDVVLDFSRPSSLKSLISYCTEKKLPLVLCTTGYSKEELNLIEETSKNIPIFKSANMSIG
EEEEEECCCCHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHCCCCCCEEECCCCEEC
INVINSLLKDISKKLYKDFDIEIIEKHHNQKVDSPSGTALLLADTIKDNVPEKLEYIYGR
HHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCEEEEEECHHCCCHHHHHHHHCC
SGHSKRTKNEIGIHAIRGGSIVGDHDVIFAGIGECIEIKHTAISREVFAIGALKASAFMK
CCCCCCCCCCCCEEEEECCCEECCCCEEEECCCCHHHHHHHHHHHHHHEEEHHHHHHHCC
GKPSGMYNMDCMLNS
CCCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12552129