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The map label for this gene is asd [H]

Identifier: 28211890

GI number: 28211890

Start: 2418869

End: 2419867

Strand: Direct

Name: asd [H]

Synonym: CTC02293

Alternate gene names: 28211890

Gene position: 2418869-2419867 (Clockwise)

Preceding gene: 28211886

Following gene: 28211891

Centisome position: 86.41

GC content: 31.13

Gene sequence:

>999_bases
TTGTGTATGAAGTATAATGTTGCTCTAGTTGGCTGTACAGGAATGGTAGGCCAAAAATTTTTAGAAATATTAGAAGAGAG
AAAGTTTCCTGTTGACAATCTTTATCTTTTTGCTTCTGCAAGATCTGCAGGTAAAAAGATTCAGTTTTGTGAAAAAGAAT
TTACAGTTGAAGAATTAAAAGAAGATAATATAAAAAACAAAAAAATAGACATCGCTTTATTCTCAGCAGGAGGTACTATA
AGTACAGAATATGCACCAATTTTTGTAAGATATGGTGCAACAGTTATTGATAATAGTAGTGCTTGGAGAATGGATCCTAG
TGTTCCTTTAGTTGTACCTGAAGTTAACCCTGATGATGTTAAATTAAGCAAAGGTATAATTGCAAATCCAAATTGTTCTA
CTATACAAGCAGTAGTTGCCTTAAAACCTTTATATGATGAGTATGGTATAAAAAGAATAGTTTACTCAACTTATCAAGCT
GTTTCTGGTGCAGGTATGGCTGGATATAATGATTTAAAGGATGGCTATAATGGAGTAGCCCCTAAAAAATTCCCTTATGC
CATAGCTGGTAATGCATTGCCACATATTGACTCTTTCTTAGATAATGGATATACAAAAGAAGAAATGAAAATGGTAAATG
AAACTAGAAAAATATTTCATAATGAAGGCTTAAAAATAACTGCTACCACTGTAAGAATTCCTGTTTTCAATAGCCATAGC
GAAAGTATAAATGTTGAATTAGAAAAAGAATTCAACCTAGAAGATGTTTTTGAGTTATATAAAAATGTCCAAGGAATAAC
TCTTGAAGATGATGTGGAAAATTTAGTTTATCCAATGGCTATAACTGCGTCAGGAAAAGATGATGTTTTTGTAGGAAGAA
TTAGAAGAGACTTTAGTATAAATAACGGATTGAATCTATGGGTAGTTGCAGATAATATAAGAAAAGGTGCTGCTCTTAAT
ACAATTCAAATTGCTGAATGTCTAATTAAAAACAAATAA

Upstream 100 bases:

>100_bases
TATAATTTATAATATTTCGAATAATTATTTTTGTGTATTTAGTATATAATTTTTCATATATCAGTTATATAATATATAAT
ATAGATAGTTTAGGAGGGAT

Downstream 100 bases:

>100_bases
CAAATAATTTAAAGTGAGGTTTTTATATGAGTATATTTAAAGGTTCTGGAGTAGCTATAGTAACACCCTTTTGTGAAAAT
GGTGTTAATTTTAAAAAGCT

Product: aspartate-semialdehyde dehydrogenase

Products: NA

Alternate protein names: ASA dehydrogenase; ASADH [H]

Number of amino acids: Translated: 332; Mature: 332

Protein sequence:

>332_residues
MCMKYNVALVGCTGMVGQKFLEILEERKFPVDNLYLFASARSAGKKIQFCEKEFTVEELKEDNIKNKKIDIALFSAGGTI
STEYAPIFVRYGATVIDNSSAWRMDPSVPLVVPEVNPDDVKLSKGIIANPNCSTIQAVVALKPLYDEYGIKRIVYSTYQA
VSGAGMAGYNDLKDGYNGVAPKKFPYAIAGNALPHIDSFLDNGYTKEEMKMVNETRKIFHNEGLKITATTVRIPVFNSHS
ESINVELEKEFNLEDVFELYKNVQGITLEDDVENLVYPMAITASGKDDVFVGRIRRDFSINNGLNLWVVADNIRKGAALN
TIQIAECLIKNK

Sequences:

>Translated_332_residues
MCMKYNVALVGCTGMVGQKFLEILEERKFPVDNLYLFASARSAGKKIQFCEKEFTVEELKEDNIKNKKIDIALFSAGGTI
STEYAPIFVRYGATVIDNSSAWRMDPSVPLVVPEVNPDDVKLSKGIIANPNCSTIQAVVALKPLYDEYGIKRIVYSTYQA
VSGAGMAGYNDLKDGYNGVAPKKFPYAIAGNALPHIDSFLDNGYTKEEMKMVNETRKIFHNEGLKITATTVRIPVFNSHS
ESINVELEKEFNLEDVFELYKNVQGITLEDDVENLVYPMAITASGKDDVFVGRIRRDFSINNGLNLWVVADNIRKGAALN
TIQIAECLIKNK
>Mature_332_residues
MCMKYNVALVGCTGMVGQKFLEILEERKFPVDNLYLFASARSAGKKIQFCEKEFTVEELKEDNIKNKKIDIALFSAGGTI
STEYAPIFVRYGATVIDNSSAWRMDPSVPLVVPEVNPDDVKLSKGIIANPNCSTIQAVVALKPLYDEYGIKRIVYSTYQA
VSGAGMAGYNDLKDGYNGVAPKKFPYAIAGNALPHIDSFLDNGYTKEEMKMVNETRKIFHNEGLKITATTVRIPVFNSHS
ESINVELEKEFNLEDVFELYKNVQGITLEDDVENLVYPMAITASGKDDVFVGRIRRDFSINNGLNLWVVADNIRKGAALN
TIQIAECLIKNK

Specific function: Unknown

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1788658, Length=341, Percent_Identity=34.0175953079179, Blast_Score=187, Evalue=7e-49,
Organism=Saccharomyces cerevisiae, GI6320362, Length=389, Percent_Identity=27.5064267352185, Blast_Score=85, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000319
- InterPro:   IPR012080
- InterPro:   IPR005986
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.11 [H]

Molecular weight: Translated: 36954; Mature: 36954

Theoretical pI: Translated: 5.30; Mature: 5.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCMKYNVALVGCTGMVGQKFLEILEERKFPVDNLYLFASARSAGKKIQFCEKEFTVEELK
CCEEEEEEEEECCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCEEEHHHHHCCHHHHH
EDNIKNKKIDIALFSAGGTISTEYAPIFVRYGATVIDNSSAWRMDPSVPLVVPEVNPDDV
HCCCCCCEEEEEEEECCCEEECCCCEEEEEECCEEEECCCCEEECCCCCEEECCCCCCCE
KLSKGIIANPNCSTIQAVVALKPLYDEYGIKRIVYSTYQAVSGAGMAGYNDLKDGYNGVA
EECCCEECCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCC
PKKFPYAIAGNALPHIDSFLDNGYTKEEMKMVNETRKIFHNEGLKITATTVRIPVFNSHS
CCCCCEEEECCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEECCCC
ESINVELEKEFNLEDVFELYKNVQGITLEDDVENLVYPMAITASGKDDVFVGRIRRDFSI
CEEEEEEECCCCHHHHHHHHHCCCCCEECCCHHHCEEEEEEEECCCCCEEEEEEEECEEC
NNGLNLWVVADNIRKGAALNTIQIAECLIKNK
CCCCEEEEEECCCCCCCCCCHHHHHHHHHCCC
>Mature Secondary Structure
MCMKYNVALVGCTGMVGQKFLEILEERKFPVDNLYLFASARSAGKKIQFCEKEFTVEELK
CCEEEEEEEEECCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCEEEHHHHHCCHHHHH
EDNIKNKKIDIALFSAGGTISTEYAPIFVRYGATVIDNSSAWRMDPSVPLVVPEVNPDDV
HCCCCCCEEEEEEEECCCEEECCCCEEEEEECCEEEECCCCEEECCCCCEEECCCCCCCE
KLSKGIIANPNCSTIQAVVALKPLYDEYGIKRIVYSTYQAVSGAGMAGYNDLKDGYNGVA
EECCCEECCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCC
PKKFPYAIAGNALPHIDSFLDNGYTKEEMKMVNETRKIFHNEGLKITATTVRIPVFNSHS
CCCCCEEEECCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEECCCC
ESINVELEKEFNLEDVFELYKNVQGITLEDDVENLVYPMAITASGKDDVFVGRIRRDFSI
CEEEEEEECCCCHHHHHHHHHCCCCCEECCCHHHCEEEEEEEECCCCCEEEEEEEECEEC
NNGLNLWVVADNIRKGAALNTIQIAECLIKNK
CCCCEEEEEECCCCCCCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]