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The map label for this gene is bcd [H]

Identifier: 28211699

GI number: 28211699

Start: 2210462

End: 2211646

Strand: Direct

Name: bcd [H]

Synonym: CTC02081

Alternate gene names: 28211699

Gene position: 2210462-2211646 (Clockwise)

Preceding gene: 28211671

Following gene: 28211707

Centisome position: 78.97

GC content: 33.84

Gene sequence:

>1185_bases
TTGCGTATATATTATTACGAGGATATATTTAAGGAGGTATATTTTATGAATTTTAAATTGACTAAGGAACAAAAATCTTT
AAAAGAAATGATTAGAGATTTTGTTAAAAAAGAAATTGAACCCATAGCTGCTAAAAGTGATGAAAGTGGTGAGTTTCCTA
AAGAAACCTTTAATAAAATGAAAGATTTGGGGCTTTTAGGTCTTCCTTTCCCAAAAGAATATGGTGGCACAGGTGGAGAT
TATTTTTCCTATGCTCTAGCTGTTGAAGAAATTTCAAAGGCTTGTGCTGCTACTGGAATTTCTTATTCTGTGTCTACATC
CTTATGTGCTTCTCCTATATTACAATATGGAACAGAAGAACAAAAACAAAAATACCTAAGTCAAATAGCTTCTGGTAAAG
TATTAGGTGGGTTTGGATTAACAGAGCCTAATGCTGGTACAGATGCTGGTGGTCAACAAACTACTGCTGTATTAGACGGT
GACCACTATATACTAAATGGAGAAAAAAAGTTTACAACTAATAGTCCTGTAGCTGATATATTTGTAGTATTTGCTATGAC
AGATAAAGAAAAAGGCCCAAAGGGTATATCTGCATTTATAGTTGAAAAATCCTTTCCTGGATTTTCTATAGGCAAACTTG
AAGATACTATGGGATTAAGAGCTGCAAAAGTAGCTGAAACTATATATAAAGATTGTAAAGTTCCAAAAGAAAATCTTCTT
GGCAAAGAAGGTGATGGATTTAAGATCGCTATGCAAACTTTAGATGGAGGTAGAATTGGTGTAGCAGCTCAGGCACTAGG
TATAGCACAGGGTGCTTTTGAAAAAGCCAAAAAGTACATGATGGAAAGAAAGCAATTTGGTAAAGCATTGTGTAAATTCC
AAGGTCTACAATGGATGATGGCAGATATGGATTTAAAAATAGAACAAGCAAGATATTTAGTTTATAAAGCTGCTTGGGAA
AAAGATAATGGATTACCTTATTCACTTTCCGCAGCAAGAGCTAAATTAGCTGCTACAGATGCAGCTATGTTTGTAACTAC
AGAGGCTGTCCAACTATTTGGTGGATATGGATATATAAAGGACTATCCTGTTGAAAGAATGATGAGAGATGCAAAAATCA
CTCAAATATATGAAGGTACAAACCAAGTACAAAAAATGGTTATTGCAGGAAATATATTTAGATAA

Upstream 100 bases:

>100_bases
TCTACCATACCTTCACCTCATCTCCGTATATTTTAATTTCTATAAACTTTCTGAAAATCCTTTCAACTTTTAAATTTATT
TAACATATTATGGAAAATAA

Downstream 100 bases:

>100_bases
ATATAAAAAAAGCCCGATAAGCTAAGCTTAATATCGGGCTTTATATAATTAAAAATTTTTCGTAATAACAATTAAGGAAA
ATTATTCATAGTTGCTCATT

Product: (3-hydroxy)butyryl-CoA dehydrogenase

Products: NA

Alternate protein names: Butyryl-CoA dehydrogenase; SCAD [H]

Number of amino acids: Translated: 394; Mature: 394

Protein sequence:

>394_residues
MRIYYYEDIFKEVYFMNFKLTKEQKSLKEMIRDFVKKEIEPIAAKSDESGEFPKETFNKMKDLGLLGLPFPKEYGGTGGD
YFSYALAVEEISKACAATGISYSVSTSLCASPILQYGTEEQKQKYLSQIASGKVLGGFGLTEPNAGTDAGGQQTTAVLDG
DHYILNGEKKFTTNSPVADIFVVFAMTDKEKGPKGISAFIVEKSFPGFSIGKLEDTMGLRAAKVAETIYKDCKVPKENLL
GKEGDGFKIAMQTLDGGRIGVAAQALGIAQGAFEKAKKYMMERKQFGKALCKFQGLQWMMADMDLKIEQARYLVYKAAWE
KDNGLPYSLSAARAKLAATDAAMFVTTEAVQLFGGYGYIKDYPVERMMRDAKITQIYEGTNQVQKMVIAGNIFR

Sequences:

>Translated_394_residues
MRIYYYEDIFKEVYFMNFKLTKEQKSLKEMIRDFVKKEIEPIAAKSDESGEFPKETFNKMKDLGLLGLPFPKEYGGTGGD
YFSYALAVEEISKACAATGISYSVSTSLCASPILQYGTEEQKQKYLSQIASGKVLGGFGLTEPNAGTDAGGQQTTAVLDG
DHYILNGEKKFTTNSPVADIFVVFAMTDKEKGPKGISAFIVEKSFPGFSIGKLEDTMGLRAAKVAETIYKDCKVPKENLL
GKEGDGFKIAMQTLDGGRIGVAAQALGIAQGAFEKAKKYMMERKQFGKALCKFQGLQWMMADMDLKIEQARYLVYKAAWE
KDNGLPYSLSAARAKLAATDAAMFVTTEAVQLFGGYGYIKDYPVERMMRDAKITQIYEGTNQVQKMVIAGNIFR
>Mature_394_residues
MRIYYYEDIFKEVYFMNFKLTKEQKSLKEMIRDFVKKEIEPIAAKSDESGEFPKETFNKMKDLGLLGLPFPKEYGGTGGD
YFSYALAVEEISKACAATGISYSVSTSLCASPILQYGTEEQKQKYLSQIASGKVLGGFGLTEPNAGTDAGGQQTTAVLDG
DHYILNGEKKFTTNSPVADIFVVFAMTDKEKGPKGISAFIVEKSFPGFSIGKLEDTMGLRAAKVAETIYKDCKVPKENLL
GKEGDGFKIAMQTLDGGRIGVAAQALGIAQGAFEKAKKYMMERKQFGKALCKFQGLQWMMADMDLKIEQARYLVYKAAWE
KDNGLPYSLSAARAKLAATDAAMFVTTEAVQLFGGYGYIKDYPVERMMRDAKITQIYEGTNQVQKMVIAGNIFR

Specific function: Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA. [C]

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=383, Percent_Identity=47.7806788511749, Blast_Score=376, Evalue=1e-104,
Organism=Homo sapiens, GI4557231, Length=377, Percent_Identity=41.1140583554377, Blast_Score=287, Evalue=1e-77,
Organism=Homo sapiens, GI226958412, Length=373, Percent_Identity=38.8739946380697, Blast_Score=287, Evalue=1e-77,
Organism=Homo sapiens, GI187960098, Length=377, Percent_Identity=41.1140583554377, Blast_Score=287, Evalue=1e-77,
Organism=Homo sapiens, GI4501859, Length=373, Percent_Identity=40.2144772117962, Blast_Score=285, Evalue=4e-77,
Organism=Homo sapiens, GI226958414, Length=368, Percent_Identity=38.0434782608696, Blast_Score=268, Evalue=7e-72,
Organism=Homo sapiens, GI7656849, Length=379, Percent_Identity=36.1477572559367, Blast_Score=254, Evalue=9e-68,
Organism=Homo sapiens, GI21361497, Length=367, Percent_Identity=40.0544959128065, Blast_Score=249, Evalue=3e-66,
Organism=Homo sapiens, GI76496475, Length=391, Percent_Identity=36.0613810741688, Blast_Score=232, Evalue=5e-61,
Organism=Homo sapiens, GI4557235, Length=391, Percent_Identity=36.0613810741688, Blast_Score=231, Evalue=6e-61,
Organism=Homo sapiens, GI4501857, Length=376, Percent_Identity=33.5106382978723, Blast_Score=224, Evalue=8e-59,
Organism=Homo sapiens, GI4503943, Length=382, Percent_Identity=30.3664921465969, Blast_Score=187, Evalue=2e-47,
Organism=Homo sapiens, GI7669494, Length=372, Percent_Identity=30.6451612903226, Blast_Score=179, Evalue=6e-45,
Organism=Homo sapiens, GI48976061, Length=317, Percent_Identity=29.3375394321767, Blast_Score=119, Evalue=6e-27,
Organism=Homo sapiens, GI211971008, Length=317, Percent_Identity=29.3375394321767, Blast_Score=118, Evalue=7e-27,
Organism=Homo sapiens, GI38505218, Length=354, Percent_Identity=27.4011299435028, Blast_Score=112, Evalue=5e-25,
Organism=Homo sapiens, GI218563752, Length=238, Percent_Identity=26.890756302521, Blast_Score=71, Evalue=1e-12,
Organism=Escherichia coli, GI1786223, Length=380, Percent_Identity=30, Blast_Score=185, Evalue=4e-48,
Organism=Escherichia coli, GI87081958, Length=382, Percent_Identity=31.6753926701571, Blast_Score=184, Evalue=1e-47,
Organism=Escherichia coli, GI87081702, Length=372, Percent_Identity=26.0752688172043, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI87082384, Length=289, Percent_Identity=25.2595155709343, Blast_Score=83, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17534899, Length=382, Percent_Identity=42.9319371727749, Blast_Score=300, Evalue=1e-81,
Organism=Caenorhabditis elegans, GI17508101, Length=371, Percent_Identity=40.1617250673854, Blast_Score=297, Evalue=6e-81,
Organism=Caenorhabditis elegans, GI17569725, Length=378, Percent_Identity=42.3280423280423, Blast_Score=293, Evalue=1e-79,
Organism=Caenorhabditis elegans, GI17506239, Length=370, Percent_Identity=38.9189189189189, Blast_Score=280, Evalue=1e-75,
Organism=Caenorhabditis elegans, GI17570075, Length=378, Percent_Identity=38.8888888888889, Blast_Score=276, Evalue=2e-74,
Organism=Caenorhabditis elegans, GI17538396, Length=373, Percent_Identity=36.7292225201072, Blast_Score=266, Evalue=2e-71,
Organism=Caenorhabditis elegans, GI17533517, Length=376, Percent_Identity=36.968085106383, Blast_Score=255, Evalue=4e-68,
Organism=Caenorhabditis elegans, GI71990804, Length=293, Percent_Identity=43.0034129692833, Blast_Score=240, Evalue=1e-63,
Organism=Caenorhabditis elegans, GI71985184, Length=398, Percent_Identity=34.1708542713568, Blast_Score=238, Evalue=4e-63,
Organism=Caenorhabditis elegans, GI17534353, Length=386, Percent_Identity=33.160621761658, Blast_Score=221, Evalue=4e-58,
Organism=Caenorhabditis elegans, GI71982178, Length=274, Percent_Identity=38.6861313868613, Blast_Score=214, Evalue=7e-56,
Organism=Caenorhabditis elegans, GI71985192, Length=345, Percent_Identity=33.6231884057971, Blast_Score=192, Evalue=2e-49,
Organism=Caenorhabditis elegans, GI32563615, Length=229, Percent_Identity=40.174672489083, Blast_Score=187, Evalue=7e-48,
Organism=Caenorhabditis elegans, GI17551932, Length=371, Percent_Identity=28.8409703504043, Blast_Score=158, Evalue=5e-39,
Organism=Caenorhabditis elegans, GI17531909, Length=237, Percent_Identity=35.4430379746835, Blast_Score=158, Evalue=5e-39,
Organism=Caenorhabditis elegans, GI17505929, Length=384, Percent_Identity=27.8645833333333, Blast_Score=155, Evalue=3e-38,
Organism=Caenorhabditis elegans, GI17562446, Length=335, Percent_Identity=28.6567164179104, Blast_Score=115, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI17531913, Length=176, Percent_Identity=31.25, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI86563381, Length=269, Percent_Identity=26.7657992565056, Blast_Score=79, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI86563383, Length=269, Percent_Identity=26.7657992565056, Blast_Score=79, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17540912, Length=371, Percent_Identity=23.4501347708895, Blast_Score=72, Evalue=7e-13,
Organism=Drosophila melanogaster, GI21356377, Length=375, Percent_Identity=47.4666666666667, Blast_Score=373, Evalue=1e-103,
Organism=Drosophila melanogaster, GI24646207, Length=375, Percent_Identity=43.2, Blast_Score=326, Evalue=2e-89,
Organism=Drosophila melanogaster, GI24660351, Length=381, Percent_Identity=41.994750656168, Blast_Score=300, Evalue=2e-81,
Organism=Drosophila melanogaster, GI24666513, Length=373, Percent_Identity=38.6058981233244, Blast_Score=278, Evalue=3e-75,
Organism=Drosophila melanogaster, GI21355753, Length=375, Percent_Identity=36, Blast_Score=251, Evalue=7e-67,
Organism=Drosophila melanogaster, GI281363737, Length=380, Percent_Identity=37.3684210526316, Blast_Score=246, Evalue=2e-65,
Organism=Drosophila melanogaster, GI19920834, Length=383, Percent_Identity=30.2872062663185, Blast_Score=184, Evalue=8e-47,
Organism=Drosophila melanogaster, GI24652780, Length=250, Percent_Identity=25.6, Blast_Score=72, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: =1.3.99.2 [H]

Molecular weight: Translated: 43558; Mature: 43558

Theoretical pI: Translated: 8.47; Mature: 8.47

Prosite motif: PS00072 ACYL_COA_DH_1 ; PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIYYYEDIFKEVYFMNFKLTKEQKSLKEMIRDFVKKEIEPIAAKSDESGEFPKETFNKM
CEEEEHHHHHHHHHHHEEEECHHHHHHHHHHHHHHHHHHCHHHCCCCCCCCCCHHHHHHH
KDLGLLGLPFPKEYGGTGGDYFSYALAVEEISKACAATGISYSVSTSLCASPILQYGTEE
HHCCCCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHCCCHH
QKQKYLSQIASGKVLGGFGLTEPNAGTDAGGQQTTAVLDGDHYILNGEKKFTTNSPVADI
HHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCEEEEECCCEEEECCCCEECCCCCHHHE
FVVFAMTDKEKGPKGISAFIVEKSFPGFSIGKLEDTMGLRAAKVAETIYKDCKVPKENLL
EEEEEECCCCCCCCCCEEEEEECCCCCCCCCCHHHHHCHHHHHHHHHHHHHCCCCHHHCC
GKEGDGFKIAMQTLDGGRIGVAAQALGIAQGAFEKAKKYMMERKQFGKALCKFQGLQWMM
CCCCCCEEEEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEE
ADMDLKIEQARYLVYKAAWEKDNGLPYSLSAARAKLAATDAAMFVTTEAVQLFGGYGYIK
CCCCCCHHHHHEEEEEECCCCCCCCCEEHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCC
DYPVERMMRDAKITQIYEGTNQVQKMVIAGNIFR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MRIYYYEDIFKEVYFMNFKLTKEQKSLKEMIRDFVKKEIEPIAAKSDESGEFPKETFNKM
CEEEEHHHHHHHHHHHEEEECHHHHHHHHHHHHHHHHHHCHHHCCCCCCCCCCHHHHHHH
KDLGLLGLPFPKEYGGTGGDYFSYALAVEEISKACAATGISYSVSTSLCASPILQYGTEE
HHCCCCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHCCCHH
QKQKYLSQIASGKVLGGFGLTEPNAGTDAGGQQTTAVLDGDHYILNGEKKFTTNSPVADI
HHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCEEEEECCCEEEECCCCEECCCCCHHHE
FVVFAMTDKEKGPKGISAFIVEKSFPGFSIGKLEDTMGLRAAKVAETIYKDCKVPKENLL
EEEEEECCCCCCCCCCEEEEEECCCCCCCCCCHHHHHCHHHHHHHHHHHHHCCCCHHHCC
GKEGDGFKIAMQTLDGGRIGVAAQALGIAQGAFEKAKKYMMERKQFGKALCKFQGLQWMM
CCCCCCEEEEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEE
ADMDLKIEQARYLVYKAAWEKDNGLPYSLSAARAKLAATDAAMFVTTEAVQLFGGYGYIK
CCCCCCHHHHHEEEEEECCCCCCCCCEEHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCC
DYPVERMMRDAKITQIYEGTNQVQKMVIAGNIFR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8655474; 11466286 [H]