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The map label for this gene is aspB [H]

Identifier: 28210993

GI number: 28210993

Start: 1409405

End: 1410604

Strand: Direct

Name: aspB [H]

Synonym: CTC01309

Alternate gene names: 28210993

Gene position: 1409405-1410604 (Clockwise)

Preceding gene: 28210983

Following gene: 28211013

Centisome position: 50.35

GC content: 29.83

Gene sequence:

>1200_bases
ATGTTAGGAGTTTCAAAGAGAGTAGAAGAGCTTAGATTTTCAGAAATAAGAAAGTTTATACCATACTCTGATGGAGCAAA
AGCTAAGGGAGTTCAGGTTCACCATTTAAATATAGGTCAACCAGATATTAAAACACCAGAGGAATTTATTAGTGCTATAA
AAAACTTTGATGAGGAAATTGTAAAATATGAAGATTCTCAAGGTAATAAAGATTTAATAGATGCCTTTGTTAAATATTAT
GAAAGTATAAATATAGACATAGATAAAGAAGATGTATATATAACAAATGGAGGTAGTGAAGCTATTTTATATGCTCTATT
AACCATATGCGACTTAGGGGATAGTGTTATAGTTCCAGAACCCTATTATACAAACTATAATACTATGGCTAAAATGGCAG
GAGTAGATATAATCTCTTTCAGAACCTATAGAGAAGATGGCTTTAGAATAAAGAGTAAAGAGGATATAATAAATTCTATA
AAAGACAATACAAAAGCTATAATGATTACAAATCCTAGTAACCCAACTGGAGTTGTTTATACTAAAGAGGAAATTAGAAT
GATTTCTGACATAGCAAAGGAAAAGGATTTGTTCATAATATCTGATGAAGTTTACAGAGAATTTGTATATGATGATCTTA
AGTTTACATCTTTTATGGACATGAAGGACATATTGGATAGAGTAATTATAATAGATAGTATATCTAAAAGATATAGTGCC
TGTGGAGCAAGAATTGGAGCTTTAATATGTAAAAATAGAAATGTTACAGAAAACTTCATGAAGATGTGCCAAGCTAGACT
TAGTGTTTCTTCTCTTGATCAAGTGGGAGCGGCTAATTTAATAAATGTTCCTAAAAGCTATATAGAAGAAGTAAGGATTG
AATATGAAAAAAGAAGAAATATATTATATGAAGGGCTTTGTGATATACCCGGTGTTCACTGTGAAAAGCCTTCAGGAGCC
TTTTATATTATAGCAAAGCTTCCTATTGACAATTCTGATGATTTTACAAAGTGGATGTTAAAAGACTTTCAATATAATAA
TAAAACCGTTATGGTTACTCCAGCAGAGGGATTTTATACTACAGAGGGCTTAGGTAAGGATGAAGTTAGATTATCCTACT
GTATTAACTCTCAAGATTTAAAAGAATCCATGTTAATATTAAAGAAAGCATTAGAAGAATATAATAAATTAAGAAAATAA

Upstream 100 bases:

>100_bases
GAAAAGTTTGAATCTTTTAAGATTATGAAATATAATATATGAATACAATGGAAAATACGTATATATAGTTATTTAAGTAA
AGCTTGAGGGAGGTAATAAT

Downstream 100 bases:

>100_bases
CCAGGAATATTTTATTCCTGGTTATGTCTTTAATTCCATAGTATAAATCTTTCTATTAAATTTAAATCCACAATCTTTAT
ATAAGTTTAAGGCCACTTTA

Product: aspartate aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 399; Mature: 399

Protein sequence:

>399_residues
MLGVSKRVEELRFSEIRKFIPYSDGAKAKGVQVHHLNIGQPDIKTPEEFISAIKNFDEEIVKYEDSQGNKDLIDAFVKYY
ESINIDIDKEDVYITNGGSEAILYALLTICDLGDSVIVPEPYYTNYNTMAKMAGVDIISFRTYREDGFRIKSKEDIINSI
KDNTKAIMITNPSNPTGVVYTKEEIRMISDIAKEKDLFIISDEVYREFVYDDLKFTSFMDMKDILDRVIIIDSISKRYSA
CGARIGALICKNRNVTENFMKMCQARLSVSSLDQVGAANLINVPKSYIEEVRIEYEKRRNILYEGLCDIPGVHCEKPSGA
FYIIAKLPIDNSDDFTKWMLKDFQYNNKTVMVTPAEGFYTTEGLGKDEVRLSYCINSQDLKESMLILKKALEEYNKLRK

Sequences:

>Translated_399_residues
MLGVSKRVEELRFSEIRKFIPYSDGAKAKGVQVHHLNIGQPDIKTPEEFISAIKNFDEEIVKYEDSQGNKDLIDAFVKYY
ESINIDIDKEDVYITNGGSEAILYALLTICDLGDSVIVPEPYYTNYNTMAKMAGVDIISFRTYREDGFRIKSKEDIINSI
KDNTKAIMITNPSNPTGVVYTKEEIRMISDIAKEKDLFIISDEVYREFVYDDLKFTSFMDMKDILDRVIIIDSISKRYSA
CGARIGALICKNRNVTENFMKMCQARLSVSSLDQVGAANLINVPKSYIEEVRIEYEKRRNILYEGLCDIPGVHCEKPSGA
FYIIAKLPIDNSDDFTKWMLKDFQYNNKTVMVTPAEGFYTTEGLGKDEVRLSYCINSQDLKESMLILKKALEEYNKLRK
>Mature_399_residues
MLGVSKRVEELRFSEIRKFIPYSDGAKAKGVQVHHLNIGQPDIKTPEEFISAIKNFDEEIVKYEDSQGNKDLIDAFVKYY
ESINIDIDKEDVYITNGGSEAILYALLTICDLGDSVIVPEPYYTNYNTMAKMAGVDIISFRTYREDGFRIKSKEDIINSI
KDNTKAIMITNPSNPTGVVYTKEEIRMISDIAKEKDLFIISDEVYREFVYDDLKFTSFMDMKDILDRVIIIDSISKRYSA
CGARIGALICKNRNVTENFMKMCQARLSVSSLDQVGAANLINVPKSYIEEVRIEYEKRRNILYEGLCDIPGVHCEKPSGA
FYIIAKLPIDNSDDFTKWMLKDFQYNNKTVMVTPAEGFYTTEGLGKDEVRLSYCINSQDLKESMLILKKALEEYNKLRK

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713254, Length=383, Percent_Identity=27.4151436031332, Blast_Score=122, Evalue=7e-28,
Organism=Homo sapiens, GI56713256, Length=383, Percent_Identity=27.4151436031332, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI95147551, Length=377, Percent_Identity=24.1379310344828, Blast_Score=119, Evalue=7e-27,
Organism=Homo sapiens, GI169881279, Length=377, Percent_Identity=24.1379310344828, Blast_Score=119, Evalue=7e-27,
Organism=Homo sapiens, GI4507369, Length=314, Percent_Identity=24.203821656051, Blast_Score=112, Evalue=6e-25,
Organism=Homo sapiens, GI169881281, Length=290, Percent_Identity=23.448275862069, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI149944424, Length=224, Percent_Identity=26.3392857142857, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI187936925, Length=252, Percent_Identity=24.2063492063492, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI14211921, Length=252, Percent_Identity=24.2063492063492, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI215599424, Length=322, Percent_Identity=25.4658385093168, Blast_Score=76, Evalue=6e-14,
Organism=Homo sapiens, GI19263340, Length=346, Percent_Identity=25.1445086705202, Blast_Score=76, Evalue=6e-14,
Organism=Homo sapiens, GI4885351, Length=375, Percent_Identity=24, Blast_Score=75, Evalue=1e-13,
Organism=Escherichia coli, GI1788627, Length=385, Percent_Identity=28.5714285714286, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1788722, Length=396, Percent_Identity=25, Blast_Score=114, Evalue=9e-27,
Organism=Escherichia coli, GI1786816, Length=327, Percent_Identity=21.4067278287462, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1790797, Length=305, Percent_Identity=24.2622950819672, Blast_Score=73, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17567663, Length=377, Percent_Identity=26.790450928382, Blast_Score=122, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI71994476, Length=397, Percent_Identity=24.6851385390428, Blast_Score=112, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI71994472, Length=397, Percent_Identity=24.6851385390428, Blast_Score=112, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI17567369, Length=374, Percent_Identity=25.668449197861, Blast_Score=111, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI71981209, Length=317, Percent_Identity=25.8675078864353, Blast_Score=80, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6322401, Length=391, Percent_Identity=26.5984654731458, Blast_Score=117, Evalue=3e-27,
Organism=Saccharomyces cerevisiae, GI6320317, Length=271, Percent_Identity=28.0442804428044, Blast_Score=99, Evalue=9e-22,
Organism=Saccharomyces cerevisiae, GI6323118, Length=340, Percent_Identity=24.7058823529412, Blast_Score=87, Evalue=5e-18,
Organism=Drosophila melanogaster, GI28573069, Length=404, Percent_Identity=26.4851485148515, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI24646114, Length=404, Percent_Identity=26.4851485148515, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI28573067, Length=404, Percent_Identity=26.4851485148515, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI28573065, Length=404, Percent_Identity=26.4851485148515, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI18859735, Length=345, Percent_Identity=25.5072463768116, Blast_Score=108, Evalue=7e-24,
Organism=Drosophila melanogaster, GI45551451, Length=345, Percent_Identity=26.0869565217391, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24641770, Length=345, Percent_Identity=26.0869565217391, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24641760, Length=345, Percent_Identity=26.0869565217391, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24641768, Length=345, Percent_Identity=26.0869565217391, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24641766, Length=345, Percent_Identity=26.0869565217391, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24641764, Length=345, Percent_Identity=26.0869565217391, Blast_Score=84, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 45716; Mature: 45716

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLGVSKRVEELRFSEIRKFIPYSDGAKAKGVQVHHLNIGQPDIKTPEEFISAIKNFDEEI
CCCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHH
VKYEDSQGNKDLIDAFVKYYESINIDIDKEDVYITNGGSEAILYALLTICDLGDSVIVPE
HHCCCCCCCHHHHHHHHHHHHHCCCEECCCCEEEECCCCHHHHHHHHHHHHCCCCEECCC
PYYTNYNTMAKMAGVDIISFRTYREDGFRIKSKEDIINSIKDNTKAIMITNPSNPTGVVY
CCCCCHHHHHHHHCCEEEEEEEECCCCCEECCHHHHHHHHCCCCCEEEEECCCCCCEEEE
TKEEIRMISDIAKEKDLFIISDEVYREFVYDDLKFTSFMDMKDILDRVIIIDSISKRYSA
EHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
CGARIGALICKNRNVTENFMKMCQARLSVSSLDQVGAANLINVPKSYIEEVRIEYEKRRN
HHHHHHHHEECCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHHHH
ILYEGLCDIPGVHCEKPSGAFYIIAKLPIDNSDDFTKWMLKDFQYNNKTVMVTPAEGFYT
HHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHCCCCCEEEEECCCCCEE
TEGLGKDEVRLSYCINSQDLKESMLILKKALEEYNKLRK
CCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLGVSKRVEELRFSEIRKFIPYSDGAKAKGVQVHHLNIGQPDIKTPEEFISAIKNFDEEI
CCCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHH
VKYEDSQGNKDLIDAFVKYYESINIDIDKEDVYITNGGSEAILYALLTICDLGDSVIVPE
HHCCCCCCCHHHHHHHHHHHHHCCCEECCCCEEEECCCCHHHHHHHHHHHHCCCCEECCC
PYYTNYNTMAKMAGVDIISFRTYREDGFRIKSKEDIINSIKDNTKAIMITNPSNPTGVVY
CCCCCHHHHHHHHCCEEEEEEEECCCCCEECCHHHHHHHHCCCCCEEEEECCCCCCEEEE
TKEEIRMISDIAKEKDLFIISDEVYREFVYDDLKFTSFMDMKDILDRVIIIDSISKRYSA
EHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
CGARIGALICKNRNVTENFMKMCQARLSVSSLDQVGAANLINVPKSYIEEVRIEYEKRRN
HHHHHHHHEECCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHHHH
ILYEGLCDIPGVHCEKPSGAFYIIAKLPIDNSDDFTKWMLKDFQYNNKTVMVTPAEGFYT
HHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHCCCCCEEEEECCCCCEE
TEGLGKDEVRLSYCINSQDLKESMLILKKALEEYNKLRK
CCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8760912; 9384377 [H]