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The map label for this gene is 28210975

Identifier: 28210975

GI number: 28210975

Start: 1384696

End: 1386267

Strand: Direct

Name: 28210975

Synonym: CTC01290

Alternate gene names: NA

Gene position: 1384696-1386267 (Clockwise)

Preceding gene: 28210974

Following gene: 28210976

Centisome position: 49.47

GC content: 33.21

Gene sequence:

>1572_bases
ATGACACTTTCTAAGCTTTTGTATTTATCAGCAATAGATTATCTAAACACAAAAAGCAAAGGAGGTGCTCATTTGAACTT
AACGTATTATATAGTAGCAACTATTATAATAGCAGTTATAGCTGTATATGTTGATTACTATATTAGGAAAAATGTATCTG
CAGCTAAAATTTCAAATGCAGAAGAAAAAGGACGTAATATAATAGAAGATGCTAAAAGAGAGGCTGAATCTAAAAAGAAA
GAAGCCATACTAGAAGCAAAAGAAGAAATGCATAGACTTAGAAACGATTTTGAAAAAGAGTCTAAAGACAGAAGAAATGA
AATTCAAAGATTAGAAAGAAGAATAATACAAAGAGAAGAAGCACTTGACAAAAAAGGTGACATGTTAGAAAAGAAAGAAG
AAAGTTTGAATAAAAAACATCAAGAACTGGAAAATAAGAAGAGTAACATAGAAAATTTATACGAAAAACAAAGAGAAGAA
TTGGAAAGGCTTGCTGGATTAACTTCAGATCAAGCTAAAGAAATGTTACTAGAAGAAGTAAGAAAAGAAATTAAACATGA
AACCGCAATGTTAATTAAAGAGGTAGAAACAAAAGCTAAAGAAGAGGCCGATAAAAAGGCAAGAGAAATAACTACATATG
CTATTCAAAGATGTGCAGCAGACCATGTTGCAGAAACCACAGTTTATGTAGTAAATCTTCCTAATGATGAAATGAAGGGA
AGAATTATAGGAAGAGAAGGTAGAAATATAAGAACACTTGAAACTTTAACAGGTGTAGATTTAATAATAGATGATACACC
TGAAGCAGTTATTCTTTCAGCTTTTGACCCTGTAAGAAGAGAAGTTGCTAGAATAGCTTTAGAAAAATTAATTATGGATG
GACGTATTCATCCAGCTAGAATTGAAGAAATGGTAGAAAAAGCCAAAAAGGAAGTTGAAAATAATATTAGAGAAGAAGGG
GAACAGGCTACATTTGAAACAAGTGTGCATGGACTTCATTCAGAACTAATAAAATTATTAGGTAGATTAAAATATAGAAC
TAGTTATGGTCAAAATGTTTTAAAACATTCTATAGAAGTATCTTACTTAGCAGGCTTAATGGCTTCGGAATTGGGAATGG
ATCCTACTTTAGCTAAAAGAGCAGGATTGCTTCACGATATAGGAAAGGCTGTTGACCATGAGGTGGAAGGACCACATGCT
ATTATAGGAGCCGAAGTGGCTAAAAGATATCATGAGTCATCCATAGTTGTAAATGCAATAGCTGCCCATCATGGAGATGA
AGAATTTGAATCTATAGAAGCAATATTAGTTCAGGCGGCAGATGCTATTTCAGCTGCTAGACCTGGAGCAAGAAGAGAAA
CTTTAGAAGCTTATATTAAAAGGTTAGAAAAACTCGAAGAGATTGCAAATTCATATGAAGGCGTAGAAAAGTCATATGCC
ATTCAAGCGGGTAGAGAGCTAAGAATAATAGTTAAACCAGAAGTAGTAGATGACGCAGGGTCCTATGAGATGGCTAGAAA
TATGGCTAAGACCATAGAGAATGAATTAGAATACCTGGTCAAATTAAGGTAA

Upstream 100 bases:

>100_bases
AATTATATACAAATATATATAACTTGACATAATAAAAAAATTAATATAAAATAAAGACAAAATCTGGTTTAGCAAAAAAG
TTAGTCCATTTGAATAAATT

Downstream 100 bases:

>100_bases
ATGTAATAAGGGAAACTCGATCCATCGAGTATGCTAAATAAAAATTAGATTAGAAAACAAAATCCTCTAAATCTTGTAAA
TTCATAGTAATTTTACAAAA

Product: phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 523; Mature: 522

Protein sequence:

>523_residues
MTLSKLLYLSAIDYLNTKSKGGAHLNLTYYIVATIIIAVIAVYVDYYIRKNVSAAKISNAEEKGRNIIEDAKREAESKKK
EAILEAKEEMHRLRNDFEKESKDRRNEIQRLERRIIQREEALDKKGDMLEKKEESLNKKHQELENKKSNIENLYEKQREE
LERLAGLTSDQAKEMLLEEVRKEIKHETAMLIKEVETKAKEEADKKAREITTYAIQRCAADHVAETTVYVVNLPNDEMKG
RIIGREGRNIRTLETLTGVDLIIDDTPEAVILSAFDPVRREVARIALEKLIMDGRIHPARIEEMVEKAKKEVENNIREEG
EQATFETSVHGLHSELIKLLGRLKYRTSYGQNVLKHSIEVSYLAGLMASELGMDPTLAKRAGLLHDIGKAVDHEVEGPHA
IIGAEVAKRYHESSIVVNAIAAHHGDEEFESIEAILVQAADAISAARPGARRETLEAYIKRLEKLEEIANSYEGVEKSYA
IQAGRELRIIVKPEVVDDAGSYEMARNMAKTIENELEYLVKLR

Sequences:

>Translated_523_residues
MTLSKLLYLSAIDYLNTKSKGGAHLNLTYYIVATIIIAVIAVYVDYYIRKNVSAAKISNAEEKGRNIIEDAKREAESKKK
EAILEAKEEMHRLRNDFEKESKDRRNEIQRLERRIIQREEALDKKGDMLEKKEESLNKKHQELENKKSNIENLYEKQREE
LERLAGLTSDQAKEMLLEEVRKEIKHETAMLIKEVETKAKEEADKKAREITTYAIQRCAADHVAETTVYVVNLPNDEMKG
RIIGREGRNIRTLETLTGVDLIIDDTPEAVILSAFDPVRREVARIALEKLIMDGRIHPARIEEMVEKAKKEVENNIREEG
EQATFETSVHGLHSELIKLLGRLKYRTSYGQNVLKHSIEVSYLAGLMASELGMDPTLAKRAGLLHDIGKAVDHEVEGPHA
IIGAEVAKRYHESSIVVNAIAAHHGDEEFESIEAILVQAADAISAARPGARRETLEAYIKRLEKLEEIANSYEGVEKSYA
IQAGRELRIIVKPEVVDDAGSYEMARNMAKTIENELEYLVKLR
>Mature_522_residues
TLSKLLYLSAIDYLNTKSKGGAHLNLTYYIVATIIIAVIAVYVDYYIRKNVSAAKISNAEEKGRNIIEDAKREAESKKKE
AILEAKEEMHRLRNDFEKESKDRRNEIQRLERRIIQREEALDKKGDMLEKKEESLNKKHQELENKKSNIENLYEKQREEL
ERLAGLTSDQAKEMLLEEVRKEIKHETAMLIKEVETKAKEEADKKAREITTYAIQRCAADHVAETTVYVVNLPNDEMKGR
IIGREGRNIRTLETLTGVDLIIDDTPEAVILSAFDPVRREVARIALEKLIMDGRIHPARIEEMVEKAKKEVENNIREEGE
QATFETSVHGLHSELIKLLGRLKYRTSYGQNVLKHSIEVSYLAGLMASELGMDPTLAKRAGLLHDIGKAVDHEVEGPHAI
IGAEVAKRYHESSIVVNAIAAHHGDEEFESIEAILVQAADAISAARPGARRETLEAYIKRLEKLEEIANSYEGVEKSYAI
QAGRELRIIVKPEVVDDAGSYEMARNMAKTIENELEYLVKLR

Specific function: Catalyzes the hydrolysis of both 2',3'-cyclic AMP and 2',3'-cyclic GMP into 3'-AMP and 3'-GMP, respectively, at the 3'- terminal of RNA

COG id: COG1418

COG function: function code R; Predicted HD superfamily hydrolase

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CNPD_CLOTE (Q895I4)

Other databases:

- EMBL:   AE015927
- RefSeq:   NP_781919.1
- ProteinModelPortal:   Q895I4
- GeneID:   1059536
- GenomeReviews:   AE015927_GR
- KEGG:   ctc:CTC01290
- NMPDR:   fig|212717.1.peg.1141
- HOGENOM:   HBG734610
- OMA:   HPGRIEE
- ProtClustDB:   PRK12704
- BioCyc:   CTET212717:CTC_01290-MONOMER
- HAMAP:   MF_00335
- InterPro:   IPR017705
- InterPro:   IPR022711
- InterPro:   IPR004087
- InterPro:   IPR004088
- InterPro:   IPR018111
- InterPro:   IPR003607
- InterPro:   IPR006675
- SMART:   SM00471
- SMART:   SM00322
- TIGRFAMs:   TIGR00277
- TIGRFAMs:   TIGR03319

Pfam domain/function: PF12072 DUF3552; PF00013 KH_1

EC number: =3.1.4.16

Molecular weight: Translated: 59446; Mature: 59314

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: PS50084 KH_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xb94cb1c)-;

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLSKLLYLSAIDYLNTKSKGGAHLNLTYYIVATIIIAVIAVYVDYYIRKNVSAAKISNA
CCHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCH
EEKGRNIIEDAKREAESKKKEAILEAKEEMHRLRNDFEKESKDRRNEIQRLERRIIQREE
HHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALDKKGDMLEKKEESLNKKHQELENKKSNIENLYEKQREELERLAGLTSDQAKEMLLEEV
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
RKEIKHETAMLIKEVETKAKEEADKKAREITTYAIQRCAADHVAETTVYVVNLPNDEMKG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCC
RIIGREGRNIRTLETLTGVDLIIDDTPEAVILSAFDPVRREVARIALEKLIMDGRIHPAR
CEECCCCCCCCHHHHHCCCEEEECCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCCHHH
IEEMVEKAKKEVENNIREEGEQATFETSVHGLHSELIKLLGRLKYRTSYGQNVLKHSIEV
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SYLAGLMASELGMDPTLAKRAGLLHDIGKAVDHEVEGPHAIIGAEVAKRYHESSIVVNAI
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
AAHHGDEEFESIEAILVQAADAISAARPGARRETLEAYIKRLEKLEEIANSYEGVEKSYA
HHHCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IQAGRELRIIVKPEVVDDAGSYEMARNMAKTIENELEYLVKLR
HHCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCH
>Mature Secondary Structure 
TLSKLLYLSAIDYLNTKSKGGAHLNLTYYIVATIIIAVIAVYVDYYIRKNVSAAKISNA
CHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCH
EEKGRNIIEDAKREAESKKKEAILEAKEEMHRLRNDFEKESKDRRNEIQRLERRIIQREE
HHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALDKKGDMLEKKEESLNKKHQELENKKSNIENLYEKQREELERLAGLTSDQAKEMLLEEV
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
RKEIKHETAMLIKEVETKAKEEADKKAREITTYAIQRCAADHVAETTVYVVNLPNDEMKG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCC
RIIGREGRNIRTLETLTGVDLIIDDTPEAVILSAFDPVRREVARIALEKLIMDGRIHPAR
CEECCCCCCCCHHHHHCCCEEEECCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCCHHH
IEEMVEKAKKEVENNIREEGEQATFETSVHGLHSELIKLLGRLKYRTSYGQNVLKHSIEV
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SYLAGLMASELGMDPTLAKRAGLLHDIGKAVDHEVEGPHAIIGAEVAKRYHESSIVVNAI
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
AAHHGDEEFESIEAILVQAADAISAARPGARRETLEAYIKRLEKLEEIANSYEGVEKSYA
HHHCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IQAGRELRIIVKPEVVDDAGSYEMARNMAKTIENELEYLVKLR
HHCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12552129