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The map label for this gene is comM [H]

Identifier: 28210943

GI number: 28210943

Start: 1345130

End: 1346704

Strand: Direct

Name: comM [H]

Synonym: CTC01257

Alternate gene names: 28210943

Gene position: 1345130-1346704 (Clockwise)

Preceding gene: 28210941

Following gene: 28210944

Centisome position: 48.05

GC content: 28.25

Gene sequence:

>1575_bases
TTGAAAGACTTCTTTTTTTATTATAAAAAAAATTTTTTTGTCAACAATGATAAGGAGGTGAAGAAAAATATGGTAGTAAA
AATAAATACAGCAACTTTTACAGGCATTGAAGGTATACCTATTAATGTAGAAGTGGATATTAATAGAGGGTTACCTAATT
TTAACATAGTTGGAATGGCGGATACTTCTATTAAAGAATCAAAGGATAGGGTTAGAAGTGCCATAATAAATTCAGGATTT
GAATTTCCGCTTGGAAAAATTACTGTTAATTTAGCTCCAGCAGATATAAAAAAAGAAGGAGCTCTTTTTGATTTACCTAT
AGCAATAGGTATACTATGTGCAACGGAACAAATAAAAATAGAAGATATTAAAGAGTATGTATTTTTAGGAGAATTATCTT
TAGTAGGAGAGTTAAAAAAAGTAAAAGGAGCGTTGCCTATAGTTGTATCTGGTATAAAAAAAGAAATTAGCAATTATGTT
ATACCTATTGAAAATAAAAATGAATGTTCAATGATAGATAAAGCTAATATATATCCCTTTAATAATTTAATAGAAGTTAT
TAATTTCCTTCAATTTAAAGATGTATATCCTTATAAAACTAATTTTGAAAAGAGTAAAAAAAATGAAGAGAGGATTGATT
TTCTTGATGTAATAGGTCAGGAAAGTGCTAAAAGAGCCCTAGAAGTTGCAGCAGCTGGAAACCATAATGTAATTTTATAT
GGTCCCCCAGGCACGGGAAAGACAATGCTTGCACAAAGAGTTACTACTATATTGCCAGAAATAACTTACGAAGAGTCTTT
AGAATGTACAAAAATATATAGTGTAGCTGGATATTTAGATGAAGAACATGGGTTTATAAATGAAAGACCTTTTAGAGAGA
TACATAATACTTCAACAAAAATTGCATTAATAGGTGGAGGGAGAAAGCTACTTCCAGGGGAAATATCCCTAGCTCATAAT
GGAGTCTTATTTTTAGATGAAATATTAGAGTTCAATAAAGGTACATTAGAGTCTTTAAGGCAACCTATAGAAAATAGAAA
AATAAAAATAACAAGAAGCACGGGAACTGTAGAATATCCATGTAATTGTATGTTGATTGCTTCATTAAACCCTTGTCCTT
GTTCTAAAGATATATGTGTATGCACTCCCTACGAAAAAGAAAAATATATAAATAAATTATCTAGAGCTTTTTTAGATAGG
ATAGATATTTACACTTCTTTATCAAAAATACAATATAGCAAGATAAAAGAAGGGCAAAGAGGAGAAAGTTCAAAAGTTGT
AAGACAGCGAATAAATAGTGCACGGGAAATTCAAAGACGGAGATTTAAAAAAGAAAATATTTTAACCAATGGAGAAATGA
ATATAAATAATATTATGAAATATTGTAAGCTAGATAAAAATTCTGTTAAATTTATGGAAAAAGTTTATAAAAAATTTAAT
TTTAGCACTAGAGTTTACTCTAGAATATTAAAAGTATCTAGAACCATTGCAGATTTAGATGAAAGAGAAAATATAATAGA
AGAAGACTTAATTGAAGCTCTTCAGTATAGAAGGTTTTTAGAAAATATAGTATAA

Upstream 100 bases:

>100_bases
GTTATTCATTAATAAAAGTGTTCCACATTTTTATTATATTATACTATAATTTCAAGAAAATACCTATTGAAAAATTAATA
AATATATTTTTAAAAGAAGT

Downstream 100 bases:

>100_bases
AAGAGGTGTATATATTATGGAGTTTGATATATGGTATTCATTAGTAAGATTCTCTAATAGAGATAAACTAAGTCTTTTAA
AAAAATTTAAAAGCACTGAA

Product: Mg(2+) chelatase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 524; Mature: 524

Protein sequence:

>524_residues
MKDFFFYYKKNFFVNNDKEVKKNMVVKINTATFTGIEGIPINVEVDINRGLPNFNIVGMADTSIKESKDRVRSAIINSGF
EFPLGKITVNLAPADIKKEGALFDLPIAIGILCATEQIKIEDIKEYVFLGELSLVGELKKVKGALPIVVSGIKKEISNYV
IPIENKNECSMIDKANIYPFNNLIEVINFLQFKDVYPYKTNFEKSKKNEERIDFLDVIGQESAKRALEVAAAGNHNVILY
GPPGTGKTMLAQRVTTILPEITYEESLECTKIYSVAGYLDEEHGFINERPFREIHNTSTKIALIGGGRKLLPGEISLAHN
GVLFLDEILEFNKGTLESLRQPIENRKIKITRSTGTVEYPCNCMLIASLNPCPCSKDICVCTPYEKEKYINKLSRAFLDR
IDIYTSLSKIQYSKIKEGQRGESSKVVRQRINSAREIQRRRFKKENILTNGEMNINNIMKYCKLDKNSVKFMEKVYKKFN
FSTRVYSRILKVSRTIADLDERENIIEEDLIEALQYRRFLENIV

Sequences:

>Translated_524_residues
MKDFFFYYKKNFFVNNDKEVKKNMVVKINTATFTGIEGIPINVEVDINRGLPNFNIVGMADTSIKESKDRVRSAIINSGF
EFPLGKITVNLAPADIKKEGALFDLPIAIGILCATEQIKIEDIKEYVFLGELSLVGELKKVKGALPIVVSGIKKEISNYV
IPIENKNECSMIDKANIYPFNNLIEVINFLQFKDVYPYKTNFEKSKKNEERIDFLDVIGQESAKRALEVAAAGNHNVILY
GPPGTGKTMLAQRVTTILPEITYEESLECTKIYSVAGYLDEEHGFINERPFREIHNTSTKIALIGGGRKLLPGEISLAHN
GVLFLDEILEFNKGTLESLRQPIENRKIKITRSTGTVEYPCNCMLIASLNPCPCSKDICVCTPYEKEKYINKLSRAFLDR
IDIYTSLSKIQYSKIKEGQRGESSKVVRQRINSAREIQRRRFKKENILTNGEMNINNIMKYCKLDKNSVKFMEKVYKKFN
FSTRVYSRILKVSRTIADLDERENIIEEDLIEALQYRRFLENIV
>Mature_524_residues
MKDFFFYYKKNFFVNNDKEVKKNMVVKINTATFTGIEGIPINVEVDINRGLPNFNIVGMADTSIKESKDRVRSAIINSGF
EFPLGKITVNLAPADIKKEGALFDLPIAIGILCATEQIKIEDIKEYVFLGELSLVGELKKVKGALPIVVSGIKKEISNYV
IPIENKNECSMIDKANIYPFNNLIEVINFLQFKDVYPYKTNFEKSKKNEERIDFLDVIGQESAKRALEVAAAGNHNVILY
GPPGTGKTMLAQRVTTILPEITYEESLECTKIYSVAGYLDEEHGFINERPFREIHNTSTKIALIGGGRKLLPGEISLAHN
GVLFLDEILEFNKGTLESLRQPIENRKIKITRSTGTVEYPCNCMLIASLNPCPCSKDICVCTPYEKEKYINKLSRAFLDR
IDIYTSLSKIQYSKIKEGQRGESSKVVRQRINSAREIQRRRFKKENILTNGEMNINNIMKYCKLDKNSVKFMEKVYKKFN
FSTRVYSRILKVSRTIADLDERENIIEEDLIEALQYRRFLENIV

Specific function: Induced during competence development. Not needed for DNA uptake. May be involved in a recombination step [H]

COG id: COG0606

COG function: function code O; Predicted ATPase with chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily [H]

Homologues:

Organism=Escherichia coli, GI145693202, Length=499, Percent_Identity=41.2825651302605, Blast_Score=394, Evalue=1e-110,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR001208
- InterPro:   IPR004482
- InterPro:   IPR000523
- InterPro:   IPR020568 [H]

Pfam domain/function: PF01078 Mg_chelatase [H]

EC number: NA

Molecular weight: Translated: 59857; Mature: 59857

Theoretical pI: Translated: 8.94; Mature: 8.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDFFFYYKKNFFVNNDKEVKKNMVVKINTATFTGIEGIPINVEVDINRGLPNFNIVGMA
CCCEEEEEECCEEECCCHHHCCCEEEEEEEEEECCCCCEEEEEEEEECCCCCCCEEEEEC
DTSIKESKDRVRSAIINSGFEFPLGKITVNLAPADIKKEGALFDLPIAIGILCATEQIKI
CCCHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCEEECHHHHHHHHCCCCEEH
EDIKEYVFLGELSLVGELKKVKGALPIVVSGIKKEISNYVIPIENKNECSMIDKANIYPF
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCH
NNLIEVINFLQFKDVYPYKTNFEKSKKNEERIDFLDVIGQESAKRALEVAAAGNHNVILY
HHHHHHHHHHHHCCCCCCCCCCCHHCCCHHHHHHHHHHCCHHHHHHHHHEECCCCEEEEE
GPPGTGKTMLAQRVTTILPEITYEESLECTKIYSVAGYLDEEHGFINERPFREIHNTSTK
CCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCCE
IALIGGGRKLLPGEISLAHNGVLFLDEILEFNKGTLESLRQPIENRKIKITRSTGTVEYP
EEEEECCCEECCCCEEECCCCCHHHHHHHHCCCCHHHHHHHHHHCCEEEEEECCCCEECC
CNCMLIASLNPCPCSKDICVCTPYEKEKYINKLSRAFLDRIDIYTSLSKIQYSKIKEGQR
CCEEEEECCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
GESSKVVRQRINSAREIQRRRFKKENILTNGEMNINNIMKYCKLDKNSVKFMEKVYKKFN
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHC
FSTRVYSRILKVSRTIADLDERENIIEEDLIEALQYRRFLENIV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKDFFFYYKKNFFVNNDKEVKKNMVVKINTATFTGIEGIPINVEVDINRGLPNFNIVGMA
CCCEEEEEECCEEECCCHHHCCCEEEEEEEEEECCCCCEEEEEEEEECCCCCCCEEEEEC
DTSIKESKDRVRSAIINSGFEFPLGKITVNLAPADIKKEGALFDLPIAIGILCATEQIKI
CCCHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCEEECHHHHHHHHCCCCEEH
EDIKEYVFLGELSLVGELKKVKGALPIVVSGIKKEISNYVIPIENKNECSMIDKANIYPF
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCH
NNLIEVINFLQFKDVYPYKTNFEKSKKNEERIDFLDVIGQESAKRALEVAAAGNHNVILY
HHHHHHHHHHHHCCCCCCCCCCCHHCCCHHHHHHHHHHCCHHHHHHHHHEECCCCEEEEE
GPPGTGKTMLAQRVTTILPEITYEESLECTKIYSVAGYLDEEHGFINERPFREIHNTSTK
CCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCCE
IALIGGGRKLLPGEISLAHNGVLFLDEILEFNKGTLESLRQPIENRKIKITRSTGTVEYP
EEEEECCCEECCCCEEECCCCCHHHHHHHHCCCCHHHHHHHHHHCCEEEEEECCCCEECC
CNCMLIASLNPCPCSKDICVCTPYEKEKYINKLSRAFLDRIDIYTSLSKIQYSKIKEGQR
CCEEEEECCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
GESSKVVRQRINSAREIQRRRFKKENILTNGEMNINNIMKYCKLDKNSVKFMEKVYKKFN
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHC
FSTRVYSRILKVSRTIADLDERENIIEEDLIEALQYRRFLENIV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800; 9457884 [H]