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The map label for this gene is rpe [H]

Identifier: 28210915

GI number: 28210915

Start: 1315038

End: 1315691

Strand: Direct

Name: rpe [H]

Synonym: CTC01227

Alternate gene names: 28210915

Gene position: 1315038-1315691 (Clockwise)

Preceding gene: 28210914

Following gene: 28210916

Centisome position: 46.98

GC content: 31.5

Gene sequence:

>654_bases
ATGGTAAAAATAGCACCTTCAATATTATCAGCAGATTTCGCAAATTTAGGTAGGGACATAGAAGCCATAGAAAAATATGG
TGCCCACGTTGTACATTTTGATGTAATGGATGGAAAATATGTTCCCAATATATCCTTTGGAGTGCCTATAATGAAAAGTA
TAAAGGGACTAACTAAATTACCCTTTGATGTACACCTTATGATAGAAGAGCCCTCAAAATACATAGAAGATTTTGCAAAA
GCAGGAGCAGATATTATTACATTTCACTATGAAGCAGAGACACATTTAGATAGAACTATAAACTACATAAAATCCTTTGG
AGTTAAAGCAGGAATCGCATTAAATCCTGGAACTCCTGTAAGTCTTATAAAAGATCTTATACCTTCCTTAGATATGGTAC
TTATAATGTCTGTTAATCCAGGTTTTGGAGGTCAAAAATATATATATTATGCTTCAGATAAAATAAGAGAACTTAAGAAA
TTAAAAGATGAACTAAATAAAGATTTAATAATAGAAGTAGATGGTGGAGTAGGTAAAGATAATATAAAAGATATAGCAAA
CTGTGGAGTAGATTTAGTTGTAGCAGGATCAGCAGTTTTTAAAGATGGTAAAATAGAGGAGAACTTAAAGGTTTTAAGAG
AGGCTTTAAGATGA

Upstream 100 bases:

>100_bases
GTGTAGTAAAAAATGCTTTAGAGCAAGGAAAAATACATAAGAAAAGATATGAATTTTATATACAAATAATAGAAGAAAAA
TTAAGGGGGAAAAATAACAA

Downstream 100 bases:

>100_bases
AAGCTTTAATAGTCTGTGGAGGAAAAGCACCAGAAAAAGAATTATTATTAGAGGAATTAAAAGATAGCGATATAATTATA
GCAGCAGATAAAGGAGCAGA

Product: ribulose-phosphate 3-epimerase

Products: NA

Alternate protein names: Pentose-5-phosphate 3-epimerase; PPE; R5P3E [H]

Number of amino acids: Translated: 217; Mature: 217

Protein sequence:

>217_residues
MVKIAPSILSADFANLGRDIEAIEKYGAHVVHFDVMDGKYVPNISFGVPIMKSIKGLTKLPFDVHLMIEEPSKYIEDFAK
AGADIITFHYEAETHLDRTINYIKSFGVKAGIALNPGTPVSLIKDLIPSLDMVLIMSVNPGFGGQKYIYYASDKIRELKK
LKDELNKDLIIEVDGGVGKDNIKDIANCGVDLVVAGSAVFKDGKIEENLKVLREALR

Sequences:

>Translated_217_residues
MVKIAPSILSADFANLGRDIEAIEKYGAHVVHFDVMDGKYVPNISFGVPIMKSIKGLTKLPFDVHLMIEEPSKYIEDFAK
AGADIITFHYEAETHLDRTINYIKSFGVKAGIALNPGTPVSLIKDLIPSLDMVLIMSVNPGFGGQKYIYYASDKIRELKK
LKDELNKDLIIEVDGGVGKDNIKDIANCGVDLVVAGSAVFKDGKIEENLKVLREALR
>Mature_217_residues
MVKIAPSILSADFANLGRDIEAIEKYGAHVVHFDVMDGKYVPNISFGVPIMKSIKGLTKLPFDVHLMIEEPSKYIEDFAK
AGADIITFHYEAETHLDRTINYIKSFGVKAGIALNPGTPVSLIKDLIPSLDMVLIMSVNPGFGGQKYIYYASDKIRELKK
LKDELNKDLIIEVDGGVGKDNIKDIANCGVDLVVAGSAVFKDGKIEENLKVLREALR

Specific function: Unknown

COG id: COG0036

COG function: function code G; Pentose-5-phosphate-3-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribulose-phosphate 3-epimerase family [H]

Homologues:

Organism=Homo sapiens, GI40385883, Length=214, Percent_Identity=40.1869158878505, Blast_Score=163, Evalue=1e-40,
Organism=Homo sapiens, GI219879828, Length=214, Percent_Identity=38.785046728972, Blast_Score=153, Evalue=1e-37,
Organism=Homo sapiens, GI24307923, Length=168, Percent_Identity=32.1428571428571, Blast_Score=98, Evalue=5e-21,
Organism=Escherichia coli, GI1789788, Length=215, Percent_Identity=50.2325581395349, Blast_Score=206, Evalue=7e-55,
Organism=Escherichia coli, GI1790523, Length=214, Percent_Identity=35.0467289719626, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI1790754, Length=206, Percent_Identity=25.7281553398058, Blast_Score=95, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI17552948, Length=219, Percent_Identity=39.2694063926941, Blast_Score=159, Evalue=7e-40,
Organism=Saccharomyces cerevisiae, GI6322341, Length=229, Percent_Identity=42.7947598253275, Blast_Score=185, Evalue=5e-48,
Organism=Drosophila melanogaster, GI24586301, Length=216, Percent_Identity=37.962962962963, Blast_Score=157, Evalue=4e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR000056
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00834 Ribul_P_3_epim [H]

EC number: =5.1.3.1 [H]

Molecular weight: Translated: 23882; Mature: 23882

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: PS01085 RIBUL_P_3_EPIMER_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKIAPSILSADFANLGRDIEAIEKYGAHVVHFDVMDGKYVPNISFGVPIMKSIKGLTKL
CCEECHHHHHHHHHHHCCHHHHHHHHCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHCC
PFDVHLMIEEPSKYIEDFAKAGADIITFHYEAETHLDRTINYIKSFGVKAGIALNPGTPV
CCEEEEEEECHHHHHHHHHHCCCEEEEEEECHHHHHHHHHHHHHHCCCCCCEEECCCCCH
SLIKDLIPSLDMVLIMSVNPGFGGQKYIYYASDKIRELKKLKDELNKDLIIEVDGGVGKD
HHHHHHHCCCCEEEEEEECCCCCCCEEEEECHHHHHHHHHHHHHCCCCEEEEECCCCCCH
NIKDIANCGVDLVVAGSAVFKDGKIEENLKVLREALR
HHHHHHHCCEEEEEECCHHCCCCCCHHHHHHHHHHHC
>Mature Secondary Structure
MVKIAPSILSADFANLGRDIEAIEKYGAHVVHFDVMDGKYVPNISFGVPIMKSIKGLTKL
CCEECHHHHHHHHHHHCCHHHHHHHHCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHCC
PFDVHLMIEEPSKYIEDFAKAGADIITFHYEAETHLDRTINYIKSFGVKAGIALNPGTPV
CCEEEEEEECHHHHHHHHHHCCCEEEEEEECHHHHHHHHHHHHHHCCCCCCEEECCCCCH
SLIKDLIPSLDMVLIMSVNPGFGGQKYIYYASDKIRELKKLKDELNKDLIIEVDGGVGKD
HHHHHHHCCCCEEEEEEECCCCCCCEEEEECHHHHHHHHHHHHHCCCCEEEEECCCCCCH
NIKDIANCGVDLVVAGSAVFKDGKIEENLKVLREALR
HHHHHHHCCEEEEEECCHHCCCCCCHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377 [H]