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The map label for this gene is udk

Identifier: 28210766

GI number: 28210766

Start: 1135167

End: 1135796

Strand: Direct

Name: udk

Synonym: CTC01064

Alternate gene names: 28210766

Gene position: 1135167-1135796 (Clockwise)

Preceding gene: 28210765

Following gene: 28210767

Centisome position: 40.55

GC content: 29.05

Gene sequence:

>630_bases
ATGAGTAAAAGACCGATATTAATAGGTATAACTGGTGGAACGGGCTCAGGAAAGAGCACTGTAAGTAAAGAAATTTGTAG
AAGATTTGATAAAGAGCTTATAGTTATGATAGAGCAAGATTCCTATTACAAGGACCAAAGTCATTTATCCATTGAAGAAA
GAGTTAAAACTAATTATGATCACCCTAATGCTTTTGATACAGAGCTTTTAGTAAAGCATTTAAAAGAGCTTTCATATTGG
AGTAAAGTGGAAAAACCTATATATGATTTTGAATTACATAATAGAAAAAATGAAACAGAAATTGTAGAACCTACTGAAAT
TATAATAGTAGAAGGAATATTAGTATTAGAAGAAAAAGAAATAAGAGATCTATTAGATATAAAGATTTATGTGGATACAG
ATGCAGATGTAAGAATAATAAGAAGACTTGTTAGAGATATAAAGGAAAGAGGAAGGTCTTTAGATTCCGTAATAAATCAA
TATTTAAATGTTGTAAGACCTATGCATATGCAATTTATAGAACCAAGTAAAAGATATGCAGATATAATAATCCCTGAGGG
AGGACATAATAAAGTCGCCATAGATATAATCGTAGGAAATATAAAACAGATGGTTCAAAAATCAGAATAA

Upstream 100 bases:

>100_bases
TCAAATGATATATAAAGCTAGGGTTAACATAGAATTAAAGAAAAATGATATGCTTATTAAAGCTAAGTAAAGTTTATTTG
AGGGGGGTAGAAGATTTACT

Downstream 100 bases:

>100_bases
AAGGATAAAAGTACCTCATTTTGACAATAATAAAGTTAAAGTGAGGTGTTTTTTATTCATAAGGAAAGATGTTATATAAT
ACTTTTGTTTTTTTTAATAT

Product: uridine kinase

Products: NA

Alternate protein names: Cytidine monophosphokinase; Uridine monophosphokinase

Number of amino acids: Translated: 209; Mature: 208

Protein sequence:

>209_residues
MSKRPILIGITGGTGSGKSTVSKEICRRFDKELIVMIEQDSYYKDQSHLSIEERVKTNYDHPNAFDTELLVKHLKELSYW
SKVEKPIYDFELHNRKNETEIVEPTEIIIVEGILVLEEKEIRDLLDIKIYVDTDADVRIIRRLVRDIKERGRSLDSVINQ
YLNVVRPMHMQFIEPSKRYADIIIPEGGHNKVAIDIIVGNIKQMVQKSE

Sequences:

>Translated_209_residues
MSKRPILIGITGGTGSGKSTVSKEICRRFDKELIVMIEQDSYYKDQSHLSIEERVKTNYDHPNAFDTELLVKHLKELSYW
SKVEKPIYDFELHNRKNETEIVEPTEIIIVEGILVLEEKEIRDLLDIKIYVDTDADVRIIRRLVRDIKERGRSLDSVINQ
YLNVVRPMHMQFIEPSKRYADIIIPEGGHNKVAIDIIVGNIKQMVQKSE
>Mature_208_residues
SKRPILIGITGGTGSGKSTVSKEICRRFDKELIVMIEQDSYYKDQSHLSIEERVKTNYDHPNAFDTELLVKHLKELSYWS
KVEKPIYDFELHNRKNETEIVEPTEIIIVEGILVLEEKEIRDLLDIKIYVDTDADVRIIRRLVRDIKERGRSLDSVINQY
LNVVRPMHMQFIEPSKRYADIIIPEGGHNKVAIDIIVGNIKQMVQKSE

Specific function: Pyrimidine salvage pathway. [C]

COG id: COG0572

COG function: function code F; Uridine kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uridine kinase family

Homologues:

Organism=Homo sapiens, GI18699734, Length=213, Percent_Identity=43.6619718309859, Blast_Score=195, Evalue=2e-50,
Organism=Homo sapiens, GI301129207, Length=210, Percent_Identity=42.3809523809524, Blast_Score=184, Evalue=4e-47,
Organism=Homo sapiens, GI57863312, Length=210, Percent_Identity=42.3809523809524, Blast_Score=184, Evalue=5e-47,
Organism=Homo sapiens, GI13899253, Length=215, Percent_Identity=41.8604651162791, Blast_Score=178, Evalue=2e-45,
Organism=Homo sapiens, GI209863022, Length=152, Percent_Identity=41.4473684210526, Blast_Score=123, Evalue=1e-28,
Organism=Escherichia coli, GI87082034, Length=209, Percent_Identity=50.2392344497608, Blast_Score=221, Evalue=2e-59,
Organism=Caenorhabditis elegans, GI17539894, Length=209, Percent_Identity=39.2344497607655, Blast_Score=178, Evalue=2e-45,
Organism=Caenorhabditis elegans, GI17539892, Length=209, Percent_Identity=39.2344497607655, Blast_Score=178, Evalue=2e-45,
Organism=Caenorhabditis elegans, GI71981181, Length=218, Percent_Identity=36.697247706422, Blast_Score=141, Evalue=2e-34,
Organism=Saccharomyces cerevisiae, GI6324339, Length=195, Percent_Identity=34.3589743589744, Blast_Score=123, Evalue=3e-29,
Organism=Saccharomyces cerevisiae, GI6320223, Length=208, Percent_Identity=27.4038461538462, Blast_Score=65, Evalue=6e-12,
Organism=Drosophila melanogaster, GI28573516, Length=204, Percent_Identity=44.1176470588235, Blast_Score=186, Evalue=1e-47,
Organism=Drosophila melanogaster, GI28573514, Length=204, Percent_Identity=44.1176470588235, Blast_Score=186, Evalue=1e-47,
Organism=Drosophila melanogaster, GI28573512, Length=204, Percent_Identity=44.1176470588235, Blast_Score=186, Evalue=1e-47,
Organism=Drosophila melanogaster, GI45550449, Length=204, Percent_Identity=44.1176470588235, Blast_Score=186, Evalue=1e-47,
Organism=Drosophila melanogaster, GI24649624, Length=219, Percent_Identity=41.5525114155251, Blast_Score=177, Evalue=5e-45,
Organism=Drosophila melanogaster, GI221458995, Length=218, Percent_Identity=41.743119266055, Blast_Score=177, Evalue=5e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): URK_CLOTE (Q896E3)

Other databases:

- EMBL:   AE015927
- RefSeq:   NP_781710.1
- ProteinModelPortal:   Q896E3
- SMR:   Q896E3
- GeneID:   1059379
- GenomeReviews:   AE015927_GR
- KEGG:   ctc:CTC01064
- NMPDR:   fig|212717.1.peg.932
- HOGENOM:   HBG527126
- OMA:   NQFVEPT
- PhylomeDB:   Q896E3
- ProtClustDB:   PRK05480
- BioCyc:   CTET212717:CTC_01064-MONOMER
- BRENDA:   2.7.1.48
- GO:   GO:0005737
- HAMAP:   MF_00551
- InterPro:   IPR006083
- InterPro:   IPR000764
- PANTHER:   PTHR10285:SF6
- PRINTS:   PR00988
- TIGRFAMs:   TIGR00235

Pfam domain/function: PF00485 PRK

EC number: =2.7.1.48

Molecular weight: Translated: 24320; Mature: 24189

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKRPILIGITGGTGSGKSTVSKEICRRFDKELIVMIEQDSYYKDQSHLSIEERVKTNYD
CCCCCEEEEEECCCCCCHHHHHHHHHHHCCHHEEEEECCCCCCCCCCCCCHHHHHHCCCC
HPNAFDTELLVKHLKELSYWSKVEKPIYDFELHNRKNETEIVEPTEIIIVEGILVLEEKE
CCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCEECCCEEEEEECEEEECHHH
IRDLLDIKIYVDTDADVRIIRRLVRDIKERGRSLDSVINQYLNVVRPMHMQFIEPSKRYA
HHHHHEEEEEEECCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCE
DIIIPEGGHNKVAIDIIVGNIKQMVQKSE
EEEEECCCCCEEEEEEEEHHHHHHHHCCC
>Mature Secondary Structure 
SKRPILIGITGGTGSGKSTVSKEICRRFDKELIVMIEQDSYYKDQSHLSIEERVKTNYD
CCCCEEEEEECCCCCCHHHHHHHHHHHCCHHEEEEECCCCCCCCCCCCCHHHHHHCCCC
HPNAFDTELLVKHLKELSYWSKVEKPIYDFELHNRKNETEIVEPTEIIIVEGILVLEEKE
CCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCEECCCEEEEEECEEEECHHH
IRDLLDIKIYVDTDADVRIIRRLVRDIKERGRSLDSVINQYLNVVRPMHMQFIEPSKRYA
HHHHHEEEEEEECCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCE
DIIIPEGGHNKVAIDIIVGNIKQMVQKSE
EEEEECCCCCEEEEEEEEHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12552129