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The map label for this gene is lytS [H]

Identifier: 28210645

GI number: 28210645

Start: 994497

End: 995717

Strand: Direct

Name: lytS [H]

Synonym: CTC00934

Alternate gene names: 28210645

Gene position: 994497-995717 (Clockwise)

Preceding gene: 28210644

Following gene: 28210646

Centisome position: 35.53

GC content: 25.31

Gene sequence:

>1221_bases
GTGTTAAATAATAGGAATTTACATGATTTAATAGATGTAAATATACTAAAAAACATTCAAGATAGACTTGCGGAAATTAC
AGGACTTGCTTATAATATAGTAAATTTTAAAGGAATACCTATTAATGAATATTCAAATTTTTCTTCATTTTGTAAAAAAA
TGAGGAGCACTCATGAAGGATTACGCATATGTTGCGATGCCAATGCCCACGCAGGGCTTGAAGCAGCATTAAGAAAAAAA
CCATATATATTTAGATGCCCTGCCGGCTTGGTAGATGTTGCAATACCCATAATTGTAAATGATACTTATCTTGGAGCAAT
TTTTTTTGGACAGGTTAGAACTAATAATGATAACCTATCGTCAATTAATAATTCAAATTACTATTTAAAAAAGCATAAAA
AATGTTCTGAATTTATAGATGATTACAATAATATTTTGTACCTAGATTATTATAAAATAGAATCAATAGCATACTTAGTT
CAAATTATTGTTAATCAGCTAGTTGAGAAAACATATTTAAAATCTATTGAGGAAGAATTGAATTTTAATAATATAAAATT
AATGAAAGAAAAGGAATATAGGATTAAACTAGAGGAAGAACTAAAAGTTTCCAAGTTAACACTATTGCAATCTAAAATAA
ATCCATACTTTTTATTTAATGCATTAAATTCCATATCAAGACTTGCATTAATAGAAGATTCCCCTAAAACCTATGAAATG
ATTGTTTTATTAGCAGAATTTTCAAGATATACTTCAAAACACATAGGGAGTAAAGTTATTTTAGAAGAAGATATAGAAAA
TATTATACTATATCTTAAAATTCAGTCCATAAGATTTAAAGATAGAATAAAGTATGAAATTAATATAAATGATAATATAA
AAAAACTAAAAATACCTTCAATGGTTTTACAATGCTTTATAGAAAATGCTGTAATACATGGATTATGTCCTAAAAAAGAA
GGTGGAACAATTAAAATTAAAGGAGAAATTTTAGAAAAAGCTGCTACTATAACAATTACTGATGATGGAGTAGGAATTTC
TAAAGACAAACTTTTTCTTATATTAAATGGAAGTGATAGAATTAAAAATAACAATGTTGGTATGAGCATATACAATGTTA
ATGAAATATTAACTAGATGTTATGGCAAGAATTATAGAGTTGAAATTGAAAGTGAAATTAATGTTGGAACTATGATAAAA
CTTAAATTTCCGTTTACTTAA

Upstream 100 bases:

>100_bases
ATAATAAAAATAGTTGTGTATATTCTTAAAGGTTTGTATAATTGATATATGGACTATACATTTAATTAATATTCAACATT
AGTCTACAGGGGGTATTTTT

Downstream 100 bases:

>100_bases
AATATAAACTTTTTTGCAAATATGTATAATGGAATTGCATATGAGGGGGAATTAATGTGTGTAGAGTAGTGCTTGCCGAT
GATGAACATTTAGAAATTGA

Product: two-component sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 406; Mature: 406

Protein sequence:

>406_residues
MLNNRNLHDLIDVNILKNIQDRLAEITGLAYNIVNFKGIPINEYSNFSSFCKKMRSTHEGLRICCDANAHAGLEAALRKK
PYIFRCPAGLVDVAIPIIVNDTYLGAIFFGQVRTNNDNLSSINNSNYYLKKHKKCSEFIDDYNNILYLDYYKIESIAYLV
QIIVNQLVEKTYLKSIEEELNFNNIKLMKEKEYRIKLEEELKVSKLTLLQSKINPYFLFNALNSISRLALIEDSPKTYEM
IVLLAEFSRYTSKHIGSKVILEEDIENIILYLKIQSIRFKDRIKYEININDNIKKLKIPSMVLQCFIENAVIHGLCPKKE
GGTIKIKGEILEKAATITITDDGVGISKDKLFLILNGSDRIKNNNVGMSIYNVNEILTRCYGKNYRVEIESEINVGTMIK
LKFPFT

Sequences:

>Translated_406_residues
MLNNRNLHDLIDVNILKNIQDRLAEITGLAYNIVNFKGIPINEYSNFSSFCKKMRSTHEGLRICCDANAHAGLEAALRKK
PYIFRCPAGLVDVAIPIIVNDTYLGAIFFGQVRTNNDNLSSINNSNYYLKKHKKCSEFIDDYNNILYLDYYKIESIAYLV
QIIVNQLVEKTYLKSIEEELNFNNIKLMKEKEYRIKLEEELKVSKLTLLQSKINPYFLFNALNSISRLALIEDSPKTYEM
IVLLAEFSRYTSKHIGSKVILEEDIENIILYLKIQSIRFKDRIKYEININDNIKKLKIPSMVLQCFIENAVIHGLCPKKE
GGTIKIKGEILEKAATITITDDGVGISKDKLFLILNGSDRIKNNNVGMSIYNVNEILTRCYGKNYRVEIESEINVGTMIK
LKFPFT
>Mature_406_residues
MLNNRNLHDLIDVNILKNIQDRLAEITGLAYNIVNFKGIPINEYSNFSSFCKKMRSTHEGLRICCDANAHAGLEAALRKK
PYIFRCPAGLVDVAIPIIVNDTYLGAIFFGQVRTNNDNLSSINNSNYYLKKHKKCSEFIDDYNNILYLDYYKIESIAYLV
QIIVNQLVEKTYLKSIEEELNFNNIKLMKEKEYRIKLEEELKVSKLTLLQSKINPYFLFNALNSISRLALIEDSPKTYEM
IVLLAEFSRYTSKHIGSKVILEEDIENIILYLKIQSIRFKDRIKYEININDNIKKLKIPSMVLQCFIENAVIHGLCPKKE
GGTIKIKGEILEKAATITITDDGVGISKDKLFLILNGSDRIKNNNVGMSIYNVNEILTRCYGKNYRVEIESEINVGTMIK
LKFPFT

Specific function: Member of the two-component regulatory system lytS/lytT that probably regulates genes involved in cell wall metabolism [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788446, Length=205, Percent_Identity=27.3170731707317, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1788723, Length=213, Percent_Identity=29.1079812206573, Blast_Score=78, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR010559
- InterPro:   IPR005467
- InterPro:   IPR011620 [H]

Pfam domain/function: PF07694 5TM-5TMR_LYT; PF01590 GAF; PF02518 HATPase_c; PF06580 His_kinase [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 46704; Mature: 46704

Theoretical pI: Translated: 8.76; Mature: 8.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNNRNLHDLIDVNILKNIQDRLAEITGLAYNIVNFKGIPINEYSNFSSFCKKMRSTHEG
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCCCHHHHHHHHHCCCCC
LRICCDANAHAGLEAALRKKPYIFRCPAGLVDVAIPIIVNDTYLGAIFFGQVRTNNDNLS
EEEEECCCCCCCHHHHHHCCCEEEECCCCHHHEEEEEEECCCEEEEEEEEEEEECCCCCC
SINNSNYYLKKHKKCSEFIDDYNNILYLDYYKIESIAYLVQIIVNQLVEKTYLKSIEEEL
CCCCCCEEEEHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
NFNNIKLMKEKEYRIKLEEELKVSKLTLLQSKINPYFLFNALNSISRLALIEDSPKTYEM
CCCCEEEEECCCEEEEEHHHHHHHHHHHHHHCCCCEEEHHHHHHHHEEEEECCCCCHHHH
IVLLAEFSRYTSKHIGSKVILEEDIENIILYLKIQSIRFKDRIKYEININDNIKKLKIPS
HHHHHHHHHHHHHHCCCEEEEHHCCCEEEEEEEEEEEEECEEEEEEEEECCCCEEEEHHH
MVLQCFIENAVIHGLCPKKEGGTIKIKGEILEKAATITITDDGVGISKDKLFLILNGSDR
HHHHHHHHHHHHCCCCCCCCCCEEEEEHHEECCEEEEEEECCCCCCCCCEEEEEECCCCC
IKNNNVGMSIYNVNEILTRCYGKNYRVEIESEINVGTMIKLKFPFT
CCCCCCCEEEEEHHHHHHHHCCCCEEEEEECCCCCEEEEEEECCCC
>Mature Secondary Structure
MLNNRNLHDLIDVNILKNIQDRLAEITGLAYNIVNFKGIPINEYSNFSSFCKKMRSTHEG
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCCCHHHHHHHHHCCCCC
LRICCDANAHAGLEAALRKKPYIFRCPAGLVDVAIPIIVNDTYLGAIFFGQVRTNNDNLS
EEEEECCCCCCCHHHHHHCCCEEEECCCCHHHEEEEEEECCCEEEEEEEEEEEECCCCCC
SINNSNYYLKKHKKCSEFIDDYNNILYLDYYKIESIAYLVQIIVNQLVEKTYLKSIEEEL
CCCCCCEEEEHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
NFNNIKLMKEKEYRIKLEEELKVSKLTLLQSKINPYFLFNALNSISRLALIEDSPKTYEM
CCCCEEEEECCCEEEEEHHHHHHHHHHHHHHCCCCEEEHHHHHHHHEEEEECCCCCHHHH
IVLLAEFSRYTSKHIGSKVILEEDIENIILYLKIQSIRFKDRIKYEININDNIKKLKIPS
HHHHHHHHHHHHHHCCCEEEEHHCCCEEEEEEEEEEEEECEEEEEEEEECCCCEEEEHHH
MVLQCFIENAVIHGLCPKKEGGTIKIKGEILEKAATITITDDGVGISKDKLFLILNGSDR
HHHHHHHHHHHHCCCCCCCCCCEEEEEHHEECCEEEEEEECCCCCCCCCEEEEEECCCCC
IKNNNVGMSIYNVNEILTRCYGKNYRVEIESEINVGTMIKLKFPFT
CCCCCCCEEEEEHHHHHHHHCCCCEEEEEECCCCCEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969504; 9384377 [H]