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The map label for this gene is 28210644

Identifier: 28210644

GI number: 28210644

Start: 993066

End: 994313

Strand: Direct

Name: 28210644

Synonym: CTC00933

Alternate gene names: NA

Gene position: 993066-994313 (Clockwise)

Preceding gene: 28210643

Following gene: 28210645

Centisome position: 35.48

GC content: 33.01

Gene sequence:

>1248_bases
ATGAGTAAAATTGCATTTATAGGTGGTTTATTAATAGATGGTACAGGAAAGGAACCTATAAAAAATTCCTTATTACTTGT
TGATAATAAAAAAATTAAATATGCTGGACCAATGATGGATGTTAATGAAGAATATGAAAAAATAGATATTACAGGAAAAA
TAATTATGCCTGGATTAATTGACACTCATCTTCATTTTAGTGGAAATAGAACTGATAATGACACTGAATGGGTGCTAGAT
CCTGTTATACAAAAAACAATTGTAGCTGTTGCTCAGGCTCGTGAAGCTCTTGAACATGGATTAACATCTGTAGGCGAAAT
TTCTCGTTCAGGTATATATATACGTAATATGATTGAAGAAGGAGTAATTCCTGGACCACGTGTAGTTACAACAGGACTTG
GTTTCTGTAGGACAGCAGGACATGGTGATTCACATAAATTACCGTTAGATTATAATAATGACTCTCATCCTTGGGCTGAG
AGAGTAGATGGACCTTGGGATCTTAGAAAAGCAATAAGAAGGAGAATTCGTGAAAATCCAGATGCTATTAAAATTTGGTC
TACAGGTGGAGGCATATGGAGACTTGATGCAAAGGCTGATTTACATTATTGTATGGAAGAAATACAAGCTGTTGTGGATG
AGTGCAACATGGTTGGACTTCCTGTATGGTCACATGCAGAAGGCTATGAAGGAGCACTAAATTCATGTAAAGCTGGAGTA
TCTGCAATTATTCATGGACAAGAACTAAATGAAGAATGTCTTGAAATAATGAAAGAAAAGGATATTACATTCTGTCCAAC
TTTACAGTTCTTCTATGAATGGTTTACTGTATATGAACCACCATATAGAGCTATTCATGATAAGTATCCAGGTAAGAATA
CTGCTGAAAAAGAGCTTAATCGTATAATTGATAATTTGCAAAACGCAAATAAAAAAGGCATTAGAATAACTGTTGGTTCT
GATTCATTTTGTAGTAGTTTAACTCCATATGGTGAATATGCTATTACAGAAATGTATACACTTAATAAAGCTGGATTAAC
AAAAATGGAAACAATTTTGGCTGCTACTAAAAATGGAGCAGAAATGCTTAGAATAGATGATATCACAGGAACTCTTGAAG
AGGGAAAATTTGCTGACCTTCTTGTTTTATCCAAAAATCCATTAGAAGATATTCACAATGTAAATACTGATAATATGGAA
ATTATTATGAAAGAAGGGGCATTTATTAAAAAAGTAAATGATAAATAA

Upstream 100 bases:

>100_bases
CTTATGCTAATTAGAGGTAAAAAAGTAGAAACTAAAGATAGTGGTGCTAACTAAAGTTAATTATAAATAGTTAAAAAGTT
ATAGTTTTGGGGGGAATTTC

Downstream 100 bases:

>100_bases
CAAAACAGGGCTTCTCTTTTGTTTAAGAGAGCCTTATTTTGTTATTGAGAATTATATTTATTATAAATTAAAAGTATATT
CATATAATAAAAATAGTTGT

Product: parathion hydrolase

Products: dialkyl phosphate; aryl alcohol

Alternate protein names: Amidohydrolase Family Protein; Xaa-Pro Dipeptidase; Prolidase; Secreted Hydrolase; Amidohydrolase Family; Imidazolonepropionase; Xaa-Pro Dipeptidase Family; Imidazolonepropionase Related Amidohydrolase; M38 Family Peptidase; Aryldialkylphosphatase Related Protein; Parathion Hydrolase; Metal-Dependent Amidohydrolase; Amidohydrolase Domain Protein; Pro-Hyp Dipeptidase; Aryldialkylphosphatase; Dipeptidase; Amidase; Aryldialkylphosphatase-Related Protein; M38 Familypeptidase; Metal-Dependent Hydrolase; Amidohydrolase Imidazolonepropionase; Xaa-Arg/Lys Peptidase; Hydrolase; Amidohydrolase Domain-Containing Protein; X-Pro Dipeptidase; Exported Adenine Deaminase-Like Amidohydrolase

Number of amino acids: Translated: 415; Mature: 414

Protein sequence:

>415_residues
MSKIAFIGGLLIDGTGKEPIKNSLLLVDNKKIKYAGPMMDVNEEYEKIDITGKIIMPGLIDTHLHFSGNRTDNDTEWVLD
PVIQKTIVAVAQAREALEHGLTSVGEISRSGIYIRNMIEEGVIPGPRVVTTGLGFCRTAGHGDSHKLPLDYNNDSHPWAE
RVDGPWDLRKAIRRRIRENPDAIKIWSTGGGIWRLDAKADLHYCMEEIQAVVDECNMVGLPVWSHAEGYEGALNSCKAGV
SAIIHGQELNEECLEIMKEKDITFCPTLQFFYEWFTVYEPPYRAIHDKYPGKNTAEKELNRIIDNLQNANKKGIRITVGS
DSFCSSLTPYGEYAITEMYTLNKAGLTKMETILAATKNGAEMLRIDDITGTLEEGKFADLLVLSKNPLEDIHNVNTDNME
IIMKEGAFIKKVNDK

Sequences:

>Translated_415_residues
MSKIAFIGGLLIDGTGKEPIKNSLLLVDNKKIKYAGPMMDVNEEYEKIDITGKIIMPGLIDTHLHFSGNRTDNDTEWVLD
PVIQKTIVAVAQAREALEHGLTSVGEISRSGIYIRNMIEEGVIPGPRVVTTGLGFCRTAGHGDSHKLPLDYNNDSHPWAE
RVDGPWDLRKAIRRRIRENPDAIKIWSTGGGIWRLDAKADLHYCMEEIQAVVDECNMVGLPVWSHAEGYEGALNSCKAGV
SAIIHGQELNEECLEIMKEKDITFCPTLQFFYEWFTVYEPPYRAIHDKYPGKNTAEKELNRIIDNLQNANKKGIRITVGS
DSFCSSLTPYGEYAITEMYTLNKAGLTKMETILAATKNGAEMLRIDDITGTLEEGKFADLLVLSKNPLEDIHNVNTDNME
IIMKEGAFIKKVNDK
>Mature_414_residues
SKIAFIGGLLIDGTGKEPIKNSLLLVDNKKIKYAGPMMDVNEEYEKIDITGKIIMPGLIDTHLHFSGNRTDNDTEWVLDP
VIQKTIVAVAQAREALEHGLTSVGEISRSGIYIRNMIEEGVIPGPRVVTTGLGFCRTAGHGDSHKLPLDYNNDSHPWAER
VDGPWDLRKAIRRRIRENPDAIKIWSTGGGIWRLDAKADLHYCMEEIQAVVDECNMVGLPVWSHAEGYEGALNSCKAGVS
AIIHGQELNEECLEIMKEKDITFCPTLQFFYEWFTVYEPPYRAIHDKYPGKNTAEKELNRIIDNLQNANKKGIRITVGSD
SFCSSLTPYGEYAITEMYTLNKAGLTKMETILAATKNGAEMLRIDDITGTLEEGKFADLLVLSKNPLEDIHNVNTDNMEI
IMKEGAFIKKVNDK

Specific function: Unknown

COG id: COG1228

COG function: function code Q; Imidazolonepropionase and related amidohydrolases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Saccharomyces cerevisiae, GI6322248, Length=323, Percent_Identity=32.5077399380805, Blast_Score=129, Evalue=1e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.1.8.1

Molecular weight: Translated: 46403; Mature: 46271

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKIAFIGGLLIDGTGKEPIKNSLLLVDNKKIKYAGPMMDVNEEYEKIDITGKIIMPGLI
CCCEEEECCEEEECCCCCCHHCCEEEEECCEEEEECCCCCCCCCHHEEEEECEEEECCEE
DTHLHFSGNRTDNDTEWVLDPVIQKTIVAVAQAREALEHGLTSVGEISRSGIYIRNMIEE
ECEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHH
GVIPGPRVVTTGLGFCRTAGHGDSHKLPLDYNNDSHPWAERVDGPWDLRKAIRRRIRENP
CCCCCCCEEECCCHHHHCCCCCCCCCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHCCC
DAIKIWSTGGGIWRLDAKADLHYCMEEIQAVVDECNMVGLPVWSHAEGYEGALNSCKAGV
CEEEEEECCCCEEEEECCCHHHHHHHHHHHHHHHCCEECCCCCCCCCCHHHHHHHHHHHH
SAIIHGQELNEECLEIMKEKDITFCPTLQFFYEWFTVYEPPYRAIHDKYPGKNTAEKELN
HHEEECCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHCCCCCCCHHHHHHH
RIIDNLQNANKKGIRITVGSDSFCSSLTPYGEYAITEMYTLNKAGLTKMETILAATKNGA
HHHHHHHCCCCCCEEEEECCCHHHHCCCCCCCCHHHHEEECCCCCHHHHHHHHHHCCCCC
EMLRIDDITGTLEEGKFADLLVLSKNPLEDIHNVNTDNMEIIMKEGAFIKKVNDK
EEEEEECCCCCCCCCCEEEEEEECCCCHHHHHCCCCCCEEEEEECCCEEEECCCC
>Mature Secondary Structure 
SKIAFIGGLLIDGTGKEPIKNSLLLVDNKKIKYAGPMMDVNEEYEKIDITGKIIMPGLI
CCEEEECCEEEECCCCCCHHCCEEEEECCEEEEECCCCCCCCCHHEEEEECEEEECCEE
DTHLHFSGNRTDNDTEWVLDPVIQKTIVAVAQAREALEHGLTSVGEISRSGIYIRNMIEE
ECEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHH
GVIPGPRVVTTGLGFCRTAGHGDSHKLPLDYNNDSHPWAERVDGPWDLRKAIRRRIRENP
CCCCCCCEEECCCHHHHCCCCCCCCCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHCCC
DAIKIWSTGGGIWRLDAKADLHYCMEEIQAVVDECNMVGLPVWSHAEGYEGALNSCKAGV
CEEEEEECCCCEEEEECCCHHHHHHHHHHHHHHHCCEECCCCCCCCCCHHHHHHHHHHHH
SAIIHGQELNEECLEIMKEKDITFCPTLQFFYEWFTVYEPPYRAIHDKYPGKNTAEKELN
HHEEECCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHCCCCCCCHHHHHHH
RIIDNLQNANKKGIRITVGSDSFCSSLTPYGEYAITEMYTLNKAGLTKMETILAATKNGA
HHHHHHHCCCCCCEEEEECCCHHHHCCCCCCCCHHHHEEECCCCCHHHHHHHHHHCCCCC
EMLRIDDITGTLEEGKFADLLVLSKNPLEDIHNVNTDNMEIIMKEGAFIKKVNDK
EEEEEECCCCCCCCCCEEEEEEECCCCHHHHHCCCCCCEEEEEECCCEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: aryl dialkyl phosphate; H2O

Specific reaction: An aryl dialkyl phosphate + H2O = dialkyl phosphate + an aryl alcohol

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA