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The map label for this gene is rocC [H]

Identifier: 28210643

GI number: 28210643

Start: 991598

End: 993019

Strand: Direct

Name: rocC [H]

Synonym: CTC00932

Alternate gene names: 28210643

Gene position: 991598-993019 (Clockwise)

Preceding gene: 28210642

Following gene: 28210644

Centisome position: 35.42

GC content: 33.83

Gene sequence:

>1422_bases
ATGTCCGCTGACACATCTACTAAAGGAGGAGGAATGAAAAAAACTTTATCCCTATGGAATTTTTTCACTATAGGATTTGG
AGCTATCATAGGTACTGGATGGGTTTTATTAGTAGGCGATTGGATGATTATAGGGGGAGGACCAATAGCTGCCATGATCG
CATTTTTAATAGGATCACTATTTTTACTTCCTATAGGAGCTGTTTTTGGTGAGCTTACATCTGCTATTCCAATTTCAGGT
GGTATAGTTGAATATGTATCACGTACTTTTGGTAATAAGCCATCATATTTTACTGGATGGTTTCTTGCTTTAGGAAATGG
AATTCTTTGTCCATGGGAAGCAATTGCTATTTCTTCATTAGTAGGAGAATTCATTCCAGCACTTAAAGTTATTCCATTAT
ATGAAGTTATGGGAGCTACAGTATATCTTCCACCACTACTTATATCACTTGCATTTGCTATTTATGTTATTCGATTAAAC
TTTAAAGGTGCATCAGAGGCTGCTAAACTTCAAGGGTTTCTTACTAAATTATTACTTGCAGGTATGGTAATTGCCATGAT
TATTTCTTTATTTAGAGGAGGACCTAAAAACTTGCAACCTATATATCAACCTAAAGCTAGTAATGCTAGATCTATTTGGG
CAGGAATTCTTCCTGTACTTGTTATGACACCATTTTTCTATGCAGGTTTTGATACTATTCCGCAACAGGCTGAAGAAGCA
TCGGAAGATTTGGATTGGAATAAATTTGGGAAAGTTATTAGTATGGTTTTAATTGCTTCAGGTATATTTTATGTAATTTG
CATATATTCCTTTGGAACCATAGTTCCTTGGCAAAAGTTTGTTACTTATACTATTCCAGCACTAACTATTTTATCAGTAA
TAGGACTTAAAATTTTTTCAAAAGTTATGATGCTTATTGCTATTATGGGACCATTAGGACCTATGAATTCCTTTTTTGGA
GCTACTGCTAGAATTTTATTGGCTATGGGACGTAAAGGACAACTTCCTGAAAAATTTAAGGAACTAGATAAAAATAATGG
AACTCCAAAGACTGCTAATATTTTAATGGCAACACTTACTATAATAGGGCCATTTTTAGGTAAAAATATGTTGGTTCCAC
TTACTAATGTTAGTTCACTAGCCTTTATATTTGCTTGCTTTATGGTAAGTTTAGCTTGTTTACGTATGAGAAGAACGGAA
CCTAACATTAAAAGACCTTATAAGGTTCCAGGAGGAAAAGTTGGAATAATACTCGCATGTATGTCTTCGCTTATTATTAT
AGGATTGTTAGTTATTCCTGGTAGTCCTGCTTCTTTAAATTTTGTTGAATGGATGGTTGTGCTTACATGGTTTTTAATAG
GATTTGCACTTATGCTAATTAGAGGTAAAAAAGTAGAAACTAAAGATAGTGGTGCTAACTAA

Upstream 100 bases:

>100_bases
CATTCATCATAAATCGAGAAAAGGACTAATATACTAAATATTGTTAGTACAGAAAAAAATTTTACTAACGATTTAATGTA
TAAGAGAGGAGGTAATAAAA

Downstream 100 bases:

>100_bases
AGTTAATTATAAATAGTTAAAAAGTTATAGTTTTGGGGGGAATTTCATGAGTAAAATTGCATTTATAGGTGGTTTATTAA
TAGATGGTACAGGAAAGGAA

Product: putative amino acid permease rocC

Products: Proton [Cytoplasm]; L-asparagine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 473; Mature: 472

Protein sequence:

>473_residues
MSADTSTKGGGMKKTLSLWNFFTIGFGAIIGTGWVLLVGDWMIIGGGPIAAMIAFLIGSLFLLPIGAVFGELTSAIPISG
GIVEYVSRTFGNKPSYFTGWFLALGNGILCPWEAIAISSLVGEFIPALKVIPLYEVMGATVYLPPLLISLAFAIYVIRLN
FKGASEAAKLQGFLTKLLLAGMVIAMIISLFRGGPKNLQPIYQPKASNARSIWAGILPVLVMTPFFYAGFDTIPQQAEEA
SEDLDWNKFGKVISMVLIASGIFYVICIYSFGTIVPWQKFVTYTIPALTILSVIGLKIFSKVMMLIAIMGPLGPMNSFFG
ATARILLAMGRKGQLPEKFKELDKNNGTPKTANILMATLTIIGPFLGKNMLVPLTNVSSLAFIFACFMVSLACLRMRRTE
PNIKRPYKVPGGKVGIILACMSSLIIIGLLVIPGSPASLNFVEWMVVLTWFLIGFALMLIRGKKVETKDSGAN

Sequences:

>Translated_473_residues
MSADTSTKGGGMKKTLSLWNFFTIGFGAIIGTGWVLLVGDWMIIGGGPIAAMIAFLIGSLFLLPIGAVFGELTSAIPISG
GIVEYVSRTFGNKPSYFTGWFLALGNGILCPWEAIAISSLVGEFIPALKVIPLYEVMGATVYLPPLLISLAFAIYVIRLN
FKGASEAAKLQGFLTKLLLAGMVIAMIISLFRGGPKNLQPIYQPKASNARSIWAGILPVLVMTPFFYAGFDTIPQQAEEA
SEDLDWNKFGKVISMVLIASGIFYVICIYSFGTIVPWQKFVTYTIPALTILSVIGLKIFSKVMMLIAIMGPLGPMNSFFG
ATARILLAMGRKGQLPEKFKELDKNNGTPKTANILMATLTIIGPFLGKNMLVPLTNVSSLAFIFACFMVSLACLRMRRTE
PNIKRPYKVPGGKVGIILACMSSLIIIGLLVIPGSPASLNFVEWMVVLTWFLIGFALMLIRGKKVETKDSGAN
>Mature_472_residues
SADTSTKGGGMKKTLSLWNFFTIGFGAIIGTGWVLLVGDWMIIGGGPIAAMIAFLIGSLFLLPIGAVFGELTSAIPISGG
IVEYVSRTFGNKPSYFTGWFLALGNGILCPWEAIAISSLVGEFIPALKVIPLYEVMGATVYLPPLLISLAFAIYVIRLNF
KGASEAAKLQGFLTKLLLAGMVIAMIISLFRGGPKNLQPIYQPKASNARSIWAGILPVLVMTPFFYAGFDTIPQQAEEAS
EDLDWNKFGKVISMVLIASGIFYVICIYSFGTIVPWQKFVTYTIPALTILSVIGLKIFSKVMMLIAIMGPLGPMNSFFGA
TARILLAMGRKGQLPEKFKELDKNNGTPKTANILMATLTIIGPFLGKNMLVPLTNVSSLAFIFACFMVSLACLRMRRTEP
NIKRPYKVPGGKVGIILACMSSLIIIGLLVIPGSPASLNFVEWMVVLTWFLIGFALMLIRGKKVETKDSGAN

Specific function: Unknown

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Homo sapiens, GI7657683, Length=349, Percent_Identity=25.5014326647564, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI87081915, Length=416, Percent_Identity=24.0384615384615, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1786602, Length=396, Percent_Identity=22.2222222222222, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR015606 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 51090; Mature: 50959

Theoretical pI: Translated: 10.17; Mature: 10.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSADTSTKGGGMKKTLSLWNFFTIGFGAIIGTGWVLLVGDWMIIGGGPIAAMIAFLIGSL
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHEEEECEEEECCCHHHHHHHHHHHHH
FLLPIGAVFGELTSAIPISGGIVEYVSRTFGNKPSYFTGWFLALGNGILCPWEAIAISSL
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCHHHHHHHHH
VGEFIPALKVIPLYEVMGATVYLPPLLISLAFAIYVIRLNFKGASEAAKLQGFLTKLLLA
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
GMVIAMIISLFRGGPKNLQPIYQPKASNARSIWAGILPVLVMTPFFYAGFDTIPQQAEEA
HHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
SEDLDWNKFGKVISMVLIASGIFYVICIYSFGTIVPWQKFVTYTIPALTILSVIGLKIFS
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
KVMMLIAIMGPLGPMNSFFGATARILLAMGRKGQLPEKFKELDKNNGTPKTANILMATLT
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHH
IIGPFLGKNMLVPLTNVSSLAFIFACFMVSLACLRMRRTEPNIKRPYKVPGGKVGIILAC
HHHHHHCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHH
MSSLIIIGLLVIPGSPASLNFVEWMVVLTWFLIGFALMLIRGKKVETKDSGAN
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
SADTSTKGGGMKKTLSLWNFFTIGFGAIIGTGWVLLVGDWMIIGGGPIAAMIAFLIGSL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHEEEECEEEECCCHHHHHHHHHHHHH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HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-asparagine [Periplasm]; Proton [Periplasm] [C]

Specific reaction: L-asparagine [Periplasm] + Proton [Periplasm] = Proton [Cytoplasm] + L-asparagine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9141694; 9384377 [H]