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The map label for this gene is rbsK [H]

Identifier: 28210620

GI number: 28210620

Start: 963177

End: 964103

Strand: Direct

Name: rbsK [H]

Synonym: CTC00909

Alternate gene names: 28210620

Gene position: 963177-964103 (Clockwise)

Preceding gene: 28210619

Following gene: 28210621

Centisome position: 34.41

GC content: 33.01

Gene sequence:

>927_bases
ATGAATGTGAAGAAGATACTAGTAATAGGTAGTTTTATGATGGATCTAGTGGCACAAACTCCAAGAGCACCAATAGAGGG
TGAAACAATTATAGGAAAGTCATTTAGTCAGTTTACAGGAGGAAAAGGTGCAAATCAAGCAGTAGCGGCTGCTAGATTAG
GTGCATATGTCACTATGATTGGAAAACTTGGAAAGGATAGCTTTGGAGAAGCTCATATAGAATCCTTAAGAAGAGAAGGT
ATAAATCATGACTATGTACTATTTGATGATGTAGAAAGTTCTGGAGTAGGTCACATAACATTAGAAGAAAACGGAAACAA
TAGAATAATTGTTATTCCTGGAGCAAACTTAAAGTTAACTCCTAAAGAAGTTGAGGATCTTGAAGACAATATTAAAAGCT
CAGATATAGTAATACTTCAACTTGAAATCCCATTTGAAACTGTATATAAGACTATTGAATTAGCACATAAACATGGAAAG
ACAATAATTTTAAATCCGGCACCGGCAGCCAAATTAAAGGAACATTTTGTAGAACTAGTTGATTATATAGTTCCTAATGA
ATCAGAGGCTTCACTATTAACTGGCATTAAAGTAAATAGTATTGAAAGTGCTAGAAAAGCAGCTAAAAGTCTCCTTAATT
TAGGATGTAAAAATGTTATAATTACACTAGGAGAAAAAGGGGTATTACTTGTAAATAATAATGAGGAAATATTTCAAGAA
TCATTTAAAGTTAAACCAGTTGATACAACTGCAGCTGGAGATTCATTTATAGGTGCATTTGCTTATTCATTAGCTAATGG
ATTAGGAAATGTAAAGTCTTTAGAATTTGCATGTGCAGTTGGAGCATTGACAGTTACGAAAATAGGTGCTCAACCATCAC
TTCCAAAGCTTACAGAAGTTGAAATGTTTATGAAAGAAAATAGATAG

Upstream 100 bases:

>100_bases
CTTAAAGAATTTAAGAGGGAAAATTTTGCAGTATTTCATCCCGGCGGAAGTCTAGGTAAGAGATTGTTTAATGAGATGAA
AAAGCTTTAATAAAAGGAGA

Downstream 100 bases:

>100_bases
TACGATAAAGTAAAAACTCACATTTATAAATGTGAGTTTTTATATAAGAAAAGAGTTATTAAATTATATAAGGGAGGGAT
TTAAATGAAATTAAGATGGG

Product: ribokinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MNVKKILVIGSFMMDLVAQTPRAPIEGETIIGKSFSQFTGGKGANQAVAAARLGAYVTMIGKLGKDSFGEAHIESLRREG
INHDYVLFDDVESSGVGHITLEENGNNRIIVIPGANLKLTPKEVEDLEDNIKSSDIVILQLEIPFETVYKTIELAHKHGK
TIILNPAPAAKLKEHFVELVDYIVPNESEASLLTGIKVNSIESARKAAKSLLNLGCKNVIITLGEKGVLLVNNNEEIFQE
SFKVKPVDTTAAGDSFIGAFAYSLANGLGNVKSLEFACAVGALTVTKIGAQPSLPKLTEVEMFMKENR

Sequences:

>Translated_308_residues
MNVKKILVIGSFMMDLVAQTPRAPIEGETIIGKSFSQFTGGKGANQAVAAARLGAYVTMIGKLGKDSFGEAHIESLRREG
INHDYVLFDDVESSGVGHITLEENGNNRIIVIPGANLKLTPKEVEDLEDNIKSSDIVILQLEIPFETVYKTIELAHKHGK
TIILNPAPAAKLKEHFVELVDYIVPNESEASLLTGIKVNSIESARKAAKSLLNLGCKNVIITLGEKGVLLVNNNEEIFQE
SFKVKPVDTTAAGDSFIGAFAYSLANGLGNVKSLEFACAVGALTVTKIGAQPSLPKLTEVEMFMKENR
>Mature_308_residues
MNVKKILVIGSFMMDLVAQTPRAPIEGETIIGKSFSQFTGGKGANQAVAAARLGAYVTMIGKLGKDSFGEAHIESLRREG
INHDYVLFDDVESSGVGHITLEENGNNRIIVIPGANLKLTPKEVEDLEDNIKSSDIVILQLEIPFETVYKTIELAHKHGK
TIILNPAPAAKLKEHFVELVDYIVPNESEASLLTGIKVNSIESARKAAKSLLNLGCKNVIITLGEKGVLLVNNNEEIFQE
SFKVKPVDTTAAGDSFIGAFAYSLANGLGNVKSLEFACAVGALTVTKIGAQPSLPKLTEVEMFMKENR

Specific function: Ribose metabolism; first step. [C]

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=293, Percent_Identity=41.296928327645, Blast_Score=194, Evalue=1e-49,
Organism=Escherichia coli, GI1790193, Length=308, Percent_Identity=39.6103896103896, Blast_Score=193, Evalue=1e-50,
Organism=Escherichia coli, GI87082343, Length=300, Percent_Identity=29.3333333333333, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1788017, Length=251, Percent_Identity=29.0836653386454, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI87081971, Length=326, Percent_Identity=25.1533742331288, Blast_Score=75, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17532905, Length=306, Percent_Identity=40.8496732026144, Blast_Score=208, Evalue=3e-54,
Organism=Caenorhabditis elegans, GI25147470, Length=308, Percent_Identity=26.2987012987013, Blast_Score=65, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6319884, Length=329, Percent_Identity=31.9148936170213, Blast_Score=117, Evalue=2e-27,
Organism=Drosophila melanogaster, GI20128807, Length=307, Percent_Identity=36.4820846905537, Blast_Score=164, Evalue=7e-41,
Organism=Drosophila melanogaster, GI24583886, Length=299, Percent_Identity=30.4347826086957, Blast_Score=130, Evalue=8e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR011877
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.15 [H]

Molecular weight: Translated: 33222; Mature: 33222

Theoretical pI: Translated: 5.70; Mature: 5.70

Prosite motif: PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVKKILVIGSFMMDLVAQTPRAPIEGETIIGKSFSQFTGGKGANQAVAAARLGAYVTMI
CCCEEEEEHHHHHHHHHHCCCCCCCCCCEEECCCHHHHCCCCCCCHHHHHHHHHHHHHHH
GKLGKDSFGEAHIESLRREGINHDYVLFDDVESSGVGHITLEENGNNRIIVIPGANLKLT
HHCCCCCCCHHHHHHHHHCCCCCCEEEEECCCCCCCEEEEEEECCCEEEEEEECCCEEEC
PKEVEDLEDNIKSSDIVILQLEIPFETVYKTIELAHKHGKTIILNPAPAAKLKEHFVELV
HHHHHHHHHCCCCCCEEEEEEECCHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHH
DYIVPNESEASLLTGIKVNSIESARKAAKSLLNLGCKNVIITLGEKGVLLVNNNEEIFQE
HHHCCCCCCCCEEECEEECCHHHHHHHHHHHHHCCCCEEEEEECCCCEEEECCCHHHHHH
SFKVKPVDTTAAGDSFIGAFAYSLANGLGNVKSLEFACAVGALTVTKIGAQPSLPKLTEV
HCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHEEEEECCCCCCCCHHHH
EMFMKENR
HHHHHCCC
>Mature Secondary Structure
MNVKKILVIGSFMMDLVAQTPRAPIEGETIIGKSFSQFTGGKGANQAVAAARLGAYVTMI
CCCEEEEEHHHHHHHHHHCCCCCCCCCCEEECCCHHHHCCCCCCCHHHHHHHHHHHHHHH
GKLGKDSFGEAHIESLRREGINHDYVLFDDVESSGVGHITLEENGNNRIIVIPGANLKLT
HHCCCCCCCHHHHHHHHHCCCCCCEEEEECCCCCCCEEEEEEECCCEEEEEEECCCEEEC
PKEVEDLEDNIKSSDIVILQLEIPFETVYKTIELAHKHGKTIILNPAPAAKLKEHFVELV
HHHHHHHHHCCCCCCEEEEEEECCHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHH
DYIVPNESEASLLTGIKVNSIESARKAAKSLLNLGCKNVIITLGEKGVLLVNNNEEIFQE
HHHCCCCCCCCEEECEEECCHHHHHHHHHHHHHCCCCEEEEEECCCCEEEECCCHHHHHH
SFKVKPVDTTAAGDSFIGAFAYSLANGLGNVKSLEFACAVGALTVTKIGAQPSLPKLTEV
HCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHEEEEECCCCCCCCHHHH
EMFMKENR
HHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]