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The map label for this gene is prc [C]

Identifier: 28210595

GI number: 28210595

Start: 936420

End: 938111

Strand: Direct

Name: prc [C]

Synonym: CTC00882

Alternate gene names: 28210595

Gene position: 936420-938111 (Clockwise)

Preceding gene: 28210591

Following gene: 28210596

Centisome position: 33.45

GC content: 25.71

Gene sequence:

>1692_bases
ATGAAAAAATTAAATAATAAAAATAATATTATAAAATTTATTCTCTACTTACTATTTATTACTTTAATAAATTCTAATAA
TGTAGTTTTTGCTAATAATAACAACGAACATGATAATTATCATAAACTAGATCAACAATTTTCGGAATTATTAAAGGACA
ATACATATAAAGAATACAATGATGGATTAATAGAGCAAATAAAATATTTAATAAATAATGTTTATTATTATGATGTACCA
GAAAGTATATCTAATGCTAAAAGTGTAGAAGAAATTATGAAAAATATAAGAGACCCTTATACTCAATACTATACAGGAGA
AGAATTTAAAAAATTACAAGAGGGAATAAACAATGTATTTTCTGGAATAGGTATATACTATAAAAAACATGAAGATGGAA
TTATAATAACGGATATGGTTCCAGGATCTTCAGCAGAATATGCAGGTTTAAAAATAGGAGATATTGTAATACAATTGAAT
AGAGAAGAAATAAAAGGTTTAAGTGTTGAAAAAATAGATAAATATATAAAGGGAGAAGAAGGAACTAAAGTTATATTGGA
TGTAAAAAGGGGAACACAAATTGTTACTTTTATTTTGCAGAGAAGAGCTGTTGAAATACCAACAGTAGATTCGAAAATAT
TGGATGAAAATATAGGATATGTACATATAAAGTCTTTTGGAAATAAGACACCAGAACTTTTTAAGAAAAGAATTGAGAAT
TTATTAAATAGTAATATAGAAAACTTAGTTGTAGATCTAAGAGGAAACCTTGGAGGATATACAAGCTCTGCATATGAAAT
AGCAGGTTACTTTATTGGAAATAAAACAGTGACTATAATGAAGGACAAAAAAGGAAATGAAACTTTATATAGAGGATCGT
CTCAAGAATTATTAAGAGATATTCCTATAATATTTATAACGGATAAAAACACAGCATCGGCATCAGAAATATTAACATCA
GCAGTAAAAGACTATGAAAGAGCTTTTATTATAGGGAATAAAACTTATGGTAAAGGAGTACAACAGACATCATTTATACT
TACAGATGAAAGTTTTTTAAAGCTTACAACTCATGAATTTTTTTCGCCTTTTGGAAGTAAAATAAATAAGATAGGTGTAA
AACCCAATTTTGATACAAAAAGTATAGACTCTTTAAAAGTTGCAGAACTCTTATTTTCAGGTGGAAAGCATAGAGAATAT
AATAGCCAATTAGTAAAATTGAGTATTGATAATAGGGAGTTTATTATAGATTTAAAAAAAGGAAAAGATAGAAACTATAG
AAGTGCTTTTAAATATATTATAGAAAGTTCTGATGGGGAGAATATAGAGATTGGAAATAAAGATAATTGGGTAAAATTTG
ATAAAAATAAAATAAGCAATGACTTTTATTTTGAGAACTTAAAAACTATGGATAGCTTAACTAAGAGTAGTAAAGATACT
GAACTTATTGTAAAATTTAATAAGGATATTCGACCTAGAACTGCAAATGAATTAAATGTAAAATTAGTAGAGGGAGCTTT
TTTTCAGGAAATTCAATTAGAATATACTATAGATAAAGGTAATGAGATTCATATAAAATGCAAGGAAGATCTAAGTACTG
ATAAAGAATATTATTTATTAGTAGAAGGTATAGAATCTATAGATGGAATGCCTCTAAAAAATGGGTCAATAGCTAGGGTA
TATGTGTATTAA

Upstream 100 bases:

>100_bases
TATAACATAATAAATGGAATTAAGTATATAGAAAAGAGGATATTGTTTAGATAAATATATTTATATGGTATAATTATTCC
AACTAGGAAGGTGGGATAAA

Downstream 100 bases:

>100_bases
ATAAAAATTTATAGAATTTTAATAAAGAAATGAAGAAATTTATGATAATATATATTTAAATAGATATTCCATTTATAAAT
AATGTGGTAAAACAGTTGAT

Product: carboxyl-terminal protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 563; Mature: 563

Protein sequence:

>563_residues
MKKLNNKNNIIKFILYLLFITLINSNNVVFANNNNEHDNYHKLDQQFSELLKDNTYKEYNDGLIEQIKYLINNVYYYDVP
ESISNAKSVEEIMKNIRDPYTQYYTGEEFKKLQEGINNVFSGIGIYYKKHEDGIIITDMVPGSSAEYAGLKIGDIVIQLN
REEIKGLSVEKIDKYIKGEEGTKVILDVKRGTQIVTFILQRRAVEIPTVDSKILDENIGYVHIKSFGNKTPELFKKRIEN
LLNSNIENLVVDLRGNLGGYTSSAYEIAGYFIGNKTVTIMKDKKGNETLYRGSSQELLRDIPIIFITDKNTASASEILTS
AVKDYERAFIIGNKTYGKGVQQTSFILTDESFLKLTTHEFFSPFGSKINKIGVKPNFDTKSIDSLKVAELLFSGGKHREY
NSQLVKLSIDNREFIIDLKKGKDRNYRSAFKYIIESSDGENIEIGNKDNWVKFDKNKISNDFYFENLKTMDSLTKSSKDT
ELIVKFNKDIRPRTANELNVKLVEGAFFQEIQLEYTIDKGNEIHIKCKEDLSTDKEYYLLVEGIESIDGMPLKNGSIARV
YVY

Sequences:

>Translated_563_residues
MKKLNNKNNIIKFILYLLFITLINSNNVVFANNNNEHDNYHKLDQQFSELLKDNTYKEYNDGLIEQIKYLINNVYYYDVP
ESISNAKSVEEIMKNIRDPYTQYYTGEEFKKLQEGINNVFSGIGIYYKKHEDGIIITDMVPGSSAEYAGLKIGDIVIQLN
REEIKGLSVEKIDKYIKGEEGTKVILDVKRGTQIVTFILQRRAVEIPTVDSKILDENIGYVHIKSFGNKTPELFKKRIEN
LLNSNIENLVVDLRGNLGGYTSSAYEIAGYFIGNKTVTIMKDKKGNETLYRGSSQELLRDIPIIFITDKNTASASEILTS
AVKDYERAFIIGNKTYGKGVQQTSFILTDESFLKLTTHEFFSPFGSKINKIGVKPNFDTKSIDSLKVAELLFSGGKHREY
NSQLVKLSIDNREFIIDLKKGKDRNYRSAFKYIIESSDGENIEIGNKDNWVKFDKNKISNDFYFENLKTMDSLTKSSKDT
ELIVKFNKDIRPRTANELNVKLVEGAFFQEIQLEYTIDKGNEIHIKCKEDLSTDKEYYLLVEGIESIDGMPLKNGSIARV
YVY
>Mature_563_residues
MKKLNNKNNIIKFILYLLFITLINSNNVVFANNNNEHDNYHKLDQQFSELLKDNTYKEYNDGLIEQIKYLINNVYYYDVP
ESISNAKSVEEIMKNIRDPYTQYYTGEEFKKLQEGINNVFSGIGIYYKKHEDGIIITDMVPGSSAEYAGLKIGDIVIQLN
REEIKGLSVEKIDKYIKGEEGTKVILDVKRGTQIVTFILQRRAVEIPTVDSKILDENIGYVHIKSFGNKTPELFKKRIEN
LLNSNIENLVVDLRGNLGGYTSSAYEIAGYFIGNKTVTIMKDKKGNETLYRGSSQELLRDIPIIFITDKNTASASEILTS
AVKDYERAFIIGNKTYGKGVQQTSFILTDESFLKLTTHEFFSPFGSKINKIGVKPNFDTKSIDSLKVAELLFSGGKHREY
NSQLVKLSIDNREFIIDLKKGKDRNYRSAFKYIIESSDGENIEIGNKDNWVKFDKNKISNDFYFENLKTMDSLTKSSKDT
ELIVKFNKDIRPRTANELNVKLVEGAFFQEIQLEYTIDKGNEIHIKCKEDLSTDKEYYLLVEGIESIDGMPLKNGSIARV
YVY

Specific function: Involved In The Cleavage Of A C-Terminal Peptide Of 11 Residues From The Precursor Form Of Penicillin-Binding Protein 3 (Pbp3). May Be Involved In Protection Of The Bacterium From Thermal And Osmotic Stresses. [C]

COG id: COG0793

COG function: function code M; Periplasmic protease

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Escherichia coli, GI1788134, Length=340, Percent_Identity=25.5882352941176, Blast_Score=108, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR005151
- InterPro:   IPR004447
- InterPro:   IPR002477 [H]

Pfam domain/function: PF00595 PDZ; PF03572 Peptidase_S41; PF01471 PG_binding_1 [H]

EC number: 3.4.21.102 [C]

Molecular weight: Translated: 64568; Mature: 64568

Theoretical pI: Translated: 6.66; Mature: 6.66

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLNNKNNIIKFILYLLFITLINSNNVVFANNNNEHDNYHKLDQQFSELLKDNTYKEYN
CCCCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHHHHCCCCCHHC
DGLIEQIKYLINNVYYYDVPESISNAKSVEEIMKNIRDPYTQYYTGEEFKKLQEGINNVF
CCHHHHHHHHHHCCEEEECCHHHCCHHHHHHHHHHHCCHHHHCCCCHHHHHHHHHHHHHH
SGIGIYYKKHEDGIIITDMVPGSSAEYAGLKIGDIVIQLNREEIKGLSVEKIDKYIKGEE
HCCCEEEEECCCCEEEEEECCCCCCCCCCEEEEEEEEEECHHHHCCCCHHHHHHHHCCCC
GTKVILDVKRGTQIVTFILQRRAVEIPTVDSKILDENIGYVHIKSFGNKTPELFKKRIEN
CCEEEEEECCCHHHHHHHHHHCCCCCCCCCHHHHHCCCCEEEEECCCCCCHHHHHHHHHH
LLNSNIENLVVDLRGNLGGYTSSAYEIAGYFIGNKTVTIMKDKKGNETLYRGSSQELLRD
HHCCCHHHEEEEECCCCCCCCCCCEEEEEEEECCEEEEEEECCCCCCCEECCCHHHHHHH
IPIIFITDKNTASASEILTSAVKDYERAFIIGNKTYGKGVQQTSFILTDESFLKLTTHEF
CCEEEEECCCCCHHHHHHHHHHHHHCEEEEEECCCCCCCCCCCEEEEECCHHHEEHHHHH
FSPFGSKINKIGVKPNFDTKSIDSLKVAELLFSGGKHREYNSQLVKLSIDNREFIIDLKK
HHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCEEEEEEECCCEEEEEECC
GKDRNYRSAFKYIIESSDGENIEIGNKDNWVKFDKNKISNDFYFENLKTMDSLTKSSKDT
CCCCCHHHHHHHHHCCCCCCEEEECCCCCCEEECCCCCCCCHHHHHHHHHHHHHCCCCCC
ELIVKFNKDIRPRTANELNVKLVEGAFFQEIQLEYTIDKGNEIHIKCKEDLSTDKEYYLL
EEEEEECCCCCCCCCCCCEEEEECCCCEEEEEEEEEECCCCEEEEEECCCCCCCCEEEEE
VEGIESIDGMPLKNGSIARVYVY
EECHHHCCCCCCCCCCEEEEEEC
>Mature Secondary Structure
MKKLNNKNNIIKFILYLLFITLINSNNVVFANNNNEHDNYHKLDQQFSELLKDNTYKEYN
CCCCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHHHHCCCCCHHC
DGLIEQIKYLINNVYYYDVPESISNAKSVEEIMKNIRDPYTQYYTGEEFKKLQEGINNVF
CCHHHHHHHHHHCCEEEECCHHHCCHHHHHHHHHHHCCHHHHCCCCHHHHHHHHHHHHHH
SGIGIYYKKHEDGIIITDMVPGSSAEYAGLKIGDIVIQLNREEIKGLSVEKIDKYIKGEE
HCCCEEEEECCCCEEEEEECCCCCCCCCCEEEEEEEEEECHHHHCCCCHHHHHHHHCCCC
GTKVILDVKRGTQIVTFILQRRAVEIPTVDSKILDENIGYVHIKSFGNKTPELFKKRIEN
CCEEEEEECCCHHHHHHHHHHCCCCCCCCCHHHHHCCCCEEEEECCCCCCHHHHHHHHHH
LLNSNIENLVVDLRGNLGGYTSSAYEIAGYFIGNKTVTIMKDKKGNETLYRGSSQELLRD
HHCCCHHHEEEEECCCCCCCCCCCEEEEEEEECCEEEEEEECCCCCCCEECCCHHHHHHH
IPIIFITDKNTASASEILTSAVKDYERAFIIGNKTYGKGVQQTSFILTDESFLKLTTHEF
CCEEEEECCCCCHHHHHHHHHHHHHCEEEEEECCCCCCCCCCCEEEEECCHHHEEHHHHH
FSPFGSKINKIGVKPNFDTKSIDSLKVAELLFSGGKHREYNSQLVKLSIDNREFIIDLKK
HHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCEEEEEEECCCEEEEEECC
GKDRNYRSAFKYIIESSDGENIEIGNKDNWVKFDKNKISNDFYFENLKTMDSLTKSSKDT
CCCCCHHHHHHHHHCCCCCCEEEECCCCCCEEECCCCCCCCHHHHHHHHHHHHHCCCCCC
ELIVKFNKDIRPRTANELNVKLVEGAFFQEIQLEYTIDKGNEIHIKCKEDLSTDKEYYLL
EEEEEECCCCCCCCCCCCEEEEECCCCEEEEEEEEEECCCCEEEEEECCCCCCCCEEEEE
VEGIESIDGMPLKNGSIARVYVY
EECHHHCCCCCCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Cleavage of the C-terminal peptide from the precursor form of penicillin-binding protein 3 [C]

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA