Click here to switch to the map view.

The map label for this gene is galE [H]

Identifier: 28210582

GI number: 28210582

Start: 920540

End: 921538

Strand: Direct

Name: galE [H]

Synonym: CTC00866

Alternate gene names: 28210582

Gene position: 920540-921538 (Clockwise)

Preceding gene: 28210581

Following gene: 28210583

Centisome position: 32.89

GC content: 32.23

Gene sequence:

>999_bases
TTGGGAGGAATAAATTTGAGTATTTTAATATGTGGTGGCGCAGGATACATCGGAAGTCATATGGTAGCTAGACTTTTAGA
AGAAAAAGAAGACATAATTATATTAGATAATTTTCAAAAAGGACATAGGAAGGCTATATTAGGGGGGAAAGTATATAAAG
GAGATATTAGGAACAAAGCCTTACTAGATAAAATATTTAATGAGAACTCAATAGAAGGAGTTATAGATTTTGCAGCTAGT
TCTTTAGTTAGAGAGAGTGTAGAAAAACCTTTAGAGTATTTTGATAACAATATAGGTGGTACTATAGTATTATTAAAAAG
TATGATAGAACATAACGTGAAAAATATCGTATTTTCATCTACAGCAGCAACCTACGGAGAACCAGAAAATATACCTATAA
GGGAAGAAGATAAAACTAATCCTACTAACCCCTACGGTGAGTCTAAATTAGCTGTAGAAAAAATATTAAAATGGTGTGAT
AAAGCTTATGGATTAAAATACACTGTTTTAAGGTATTTTAATGCAGCGGGAGCATATGACACAGGAAAGATAGGAGAAGA
CCATAGGCCAGAAACTCATTTAATTCCTATAATAATAGAAGTAGCTTTAGGAAAAAGGGATAAAATACAAGTATTTGGGA
ATGATTATAATACAAAGGATGGAACTTGTATAAGAGACTATGTTCACGTTATGGATCTTACAGAGGCTCATCTCTTAGCC
ATGAATAAATTAAAGAATGGAGGAAAAAGCGGAATTTATAATCTAGGAAATGGAGAAGGATTTTCAGTAAAGGAAGTAAT
AGATATGGTCCAAAAAGTTACAGGTAGAAAAATAAAGTGGGAAGTAGCAAATAGAAGAAAGGGAGATCCGAGAGTATTAA
TAGCATCTTCTGAAAAGGCAAAAACACAGTTAGGTTGGCACCCAAAATATAATTCTTTAGAAAAGATTATAGAAACAGCT
TGGAAATGGCATAAAAATAACCCAGATGGTTATATGTAG

Upstream 100 bases:

>100_bases
GATATGGCTAAAAAGAATAATAAGTTAAAAGTTTTAGAATCAAAAGAAGAATTGAATTTTTATATAAAATTACAATTAAA
GAGTATATAATATTAGAACT

Downstream 100 bases:

>100_bases
TTTTATAGGCTATAGTGTTTATTTTAGTAAGACACTATAGCTATTCTATGTATAAATTTGTATAAAAATTTAATAAATTG
TAACCTTTCTATAAAATATT

Product: UDP-glucose 4-epimerase, galE

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 332; Mature: 331

Protein sequence:

>332_residues
MGGINLSILICGGAGYIGSHMVARLLEEKEDIIILDNFQKGHRKAILGGKVYKGDIRNKALLDKIFNENSIEGVIDFAAS
SLVRESVEKPLEYFDNNIGGTIVLLKSMIEHNVKNIVFSSTAATYGEPENIPIREEDKTNPTNPYGESKLAVEKILKWCD
KAYGLKYTVLRYFNAAGAYDTGKIGEDHRPETHLIPIIIEVALGKRDKIQVFGNDYNTKDGTCIRDYVHVMDLTEAHLLA
MNKLKNGGKSGIYNLGNGEGFSVKEVIDMVQKVTGRKIKWEVANRRKGDPRVLIASSEKAKTQLGWHPKYNSLEKIIETA
WKWHKNNPDGYM

Sequences:

>Translated_332_residues
MGGINLSILICGGAGYIGSHMVARLLEEKEDIIILDNFQKGHRKAILGGKVYKGDIRNKALLDKIFNENSIEGVIDFAAS
SLVRESVEKPLEYFDNNIGGTIVLLKSMIEHNVKNIVFSSTAATYGEPENIPIREEDKTNPTNPYGESKLAVEKILKWCD
KAYGLKYTVLRYFNAAGAYDTGKIGEDHRPETHLIPIIIEVALGKRDKIQVFGNDYNTKDGTCIRDYVHVMDLTEAHLLA
MNKLKNGGKSGIYNLGNGEGFSVKEVIDMVQKVTGRKIKWEVANRRKGDPRVLIASSEKAKTQLGWHPKYNSLEKIIETA
WKWHKNNPDGYM
>Mature_331_residues
GGINLSILICGGAGYIGSHMVARLLEEKEDIIILDNFQKGHRKAILGGKVYKGDIRNKALLDKIFNENSIEGVIDFAASS
LVRESVEKPLEYFDNNIGGTIVLLKSMIEHNVKNIVFSSTAATYGEPENIPIREEDKTNPTNPYGESKLAVEKILKWCDK
AYGLKYTVLRYFNAAGAYDTGKIGEDHRPETHLIPIIIEVALGKRDKIQVFGNDYNTKDGTCIRDYVHVMDLTEAHLLAM
NKLKNGGKSGIYNLGNGEGFSVKEVIDMVQKVTGRKIKWEVANRRKGDPRVLIASSEKAKTQLGWHPKYNSLEKIIETAW
KWHKNNPDGYM

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=341, Percent_Identity=40.7624633431085, Blast_Score=263, Evalue=1e-70,
Organism=Homo sapiens, GI56118217, Length=341, Percent_Identity=40.7624633431085, Blast_Score=263, Evalue=1e-70,
Organism=Homo sapiens, GI189083684, Length=341, Percent_Identity=40.7624633431085, Blast_Score=263, Evalue=1e-70,
Organism=Homo sapiens, GI7657641, Length=343, Percent_Identity=28.2798833819242, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI42516563, Length=309, Percent_Identity=25.2427184466019, Blast_Score=88, Evalue=1e-17,
Organism=Escherichia coli, GI1786974, Length=337, Percent_Identity=43.9169139465875, Blast_Score=280, Evalue=7e-77,
Organism=Escherichia coli, GI48994969, Length=356, Percent_Identity=27.5280898876405, Blast_Score=94, Evalue=9e-21,
Organism=Escherichia coli, GI1788353, Length=363, Percent_Identity=28.099173553719, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI1790049, Length=267, Percent_Identity=26.5917602996255, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI1788365, Length=340, Percent_Identity=22.0588235294118, Blast_Score=62, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI71982035, Length=346, Percent_Identity=38.4393063583815, Blast_Score=244, Evalue=6e-65,
Organism=Caenorhabditis elegans, GI71982038, Length=348, Percent_Identity=38.2183908045977, Blast_Score=243, Evalue=1e-64,
Organism=Caenorhabditis elegans, GI17539532, Length=325, Percent_Identity=24.3076923076923, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17568069, Length=346, Percent_Identity=27.7456647398844, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI115532424, Length=347, Percent_Identity=25.9365994236311, Blast_Score=76, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6319493, Length=343, Percent_Identity=40.2332361516035, Blast_Score=245, Evalue=5e-66,
Organism=Drosophila melanogaster, GI19923002, Length=344, Percent_Identity=39.5348837209302, Blast_Score=256, Evalue=2e-68,
Organism=Drosophila melanogaster, GI21356223, Length=327, Percent_Identity=24.7706422018349, Blast_Score=79, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 37184; Mature: 37053

Theoretical pI: Translated: 8.89; Mature: 8.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGGINLSILICGGAGYIGSHMVARLLEEKEDIIILDNFQKGHRKAILGGKVYKGDIRNKA
CCCCEEEEEEECCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCEEEECCEEEECCCCHHH
LLDKIFNENSIEGVIDFAASSLVRESVEKPLEYFDNNIGGTIVLLKSMIEHNVKNIVFSS
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHEEEEC
TAATYGEPENIPIREEDKTNPTNPYGESKLAVEKILKWCDKAYGLKYTVLRYFNAAGAYD
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCC
TGKIGEDHRPETHLIPIIIEVALGKRDKIQVFGNDYNTKDGTCIRDYVHVMDLTEAHLLA
CCCCCCCCCCCCCHHEEEEEEECCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHH
MNKLKNGGKSGIYNLGNGEGFSVKEVIDMVQKVTGRKIKWEVANRRKGDPRVLIASSEKA
HHHHCCCCCCCCEECCCCCCCCHHHHHHHHHHHHCCEEEEEECCCCCCCCEEEEECCCCH
KTQLGWHPKYNSLEKIIETAWKWHKNNPDGYM
HHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
GGINLSILICGGAGYIGSHMVARLLEEKEDIIILDNFQKGHRKAILGGKVYKGDIRNKA
CCCEEEEEEECCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCEEEECCEEEECCCCHHH
LLDKIFNENSIEGVIDFAASSLVRESVEKPLEYFDNNIGGTIVLLKSMIEHNVKNIVFSS
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHEEEEC
TAATYGEPENIPIREEDKTNPTNPYGESKLAVEKILKWCDKAYGLKYTVLRYFNAAGAYD
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCC
TGKIGEDHRPETHLIPIIIEVALGKRDKIQVFGNDYNTKDGTCIRDYVHVMDLTEAHLLA
CCCCCCCCCCCCCHHEEEEEEECCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHH
MNKLKNGGKSGIYNLGNGEGFSVKEVIDMVQKVTGRKIKWEVANRRKGDPRVLIASSEKA
HHHHCCCCCCCCEECCCCCCCCHHHHHHHHHHHHCCEEEEEECCCCCCCCEEEEECCCCH
KTQLGWHPKYNSLEKIIETAWKWHKNNPDGYM
HHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]