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The map label for this gene is pgcA [H]

Identifier: 28210496

GI number: 28210496

Start: 824484

End: 826205

Strand: Direct

Name: pgcA [H]

Synonym: CTC00779

Alternate gene names: 28210496

Gene position: 824484-826205 (Clockwise)

Preceding gene: 28210495

Following gene: 28210497

Centisome position: 29.45

GC content: 29.62

Gene sequence:

>1722_bases
ATGAATTATATGAGAATTTATAATGAGTGGTTAAATAACGATTACTTTGATGATGTTACAAAAGAAGAATTAAAAAGTAT
AAAAGATAATCCTAAGGAAATAGAAGATAGATTTTATAAAAATTTAGAGTTTGGAACAGCAGGACTTAGAGGTAAAATTG
CAGCTGGTACAAATAGAATGAATAAATATATAATAGCTAAAGTAACTCAAGGACTTGCAAATTTTATAGCAAAACAAGGT
AAAGAGGTAATGAATAGGGGGGTAGCTATAGCCTATGATTGTAGGCATTATTCAGATGTGTTTGCAAAAACTGCAGCATT
AGTTTTGGCTGCAAATGGAATTAAAGCATATTTATTTGAAGATTTAAGACCAACACCAGAGTTATCCTATACAGTAAGGA
GATTAAATACAATATCTGGAATAGTAGTAACAGCTAGTCATAACCCTAAAGATTATAATGGATATAAAGTGTACTGGGAA
GATGGAGCACAAATATTAGATAAGATAGCCAAACCTGTTACAGAAGAGATAAATAACATTAAAAATTTTAAAGAAATAAA
GTCCATATCTGAAGAAGAAGCTTTAGAAAAAGGTCTTTTAGAGATATTAGGAAAAGAAATAGATGATGAATATATAGAAA
AAGTTAAGGCTTTATCTATAAGAAATGATATAGATAAGGACATAAAAATAGTTTACACACCATTAAATGGAACGGGAAAT
ATTCCAGTAAGAAGAGTTCTAAGGGAAAGAAGATTTACCAATGTAATAGTTGTGCCAGAACAGGAAAATCCAGATCCAGA
TTTTACCACAGTAGGTTATCCAAATCCAGAGGATATAAAAGCCTTTGAATATGCTAAAAGATTAGGAGAGAAAGAAAGAG
CAGATTTATTATTAGCAACAGATCCTGATTGTGACAGACTAGCAGTAATGGCTAGAAATAATCGTGGAGAATTTGTGGCG
TTAAATGGTAATCAAACAGGAGCTGTTTTAATAAAATATCTTGTGGAAAGTAAAGTAGAAAAGGGAACTTTACCTGAGAA
ACCAATGATAGTAAAATCAGTAGTTACTGGTGACATGGGTAAAGTTGTAGGAGAAAAATATGGTGTTACTACCTTTGAAT
CTCTTACAGGATTTAAAAATATTTGTGGTAAAGAAATGGAAATGAATAAAAAAGGATATAATTTTATTTTTGGATATGAA
GAAAGCATAGGCTATACAGCTGGGGACTTTGTTAAAGATAAAGATGGAGTTATTTCAGCAATGTTTTTATGTGAGGCAGC
GGCTTATTATAAAACACAAGGTAAAACTTTAATAGATGTGTTAAATGACATGTATAATGAATTTGGATATTATAGGGAAA
ATTTAATTTCACTTATATTAGAAGGTGTTGAAGGACAAAGAAGAATAGGAAGAATGATGGAAGCATATAGGAATGAATTT
CCTAAAATTATAGGAGATAATAAACTTATAAAGTATATAGACATAGATAAAGGAAAAGAAATTGATTTTATAACTAGGGA
AGAAAAATCAGTAGAATTTCCTAAATCAAATGTACTTAAATTTATATTAGAAGATGGATCATGGTATGCTATTAGACCAT
CGGGTACAGAACCCAAAATAAAAATATACTTATATTCTAAAGGGCATACTTTAAAAGATTCAGAAGATAAGTTGAAAATC
ATGGAAAAGACTATTATGGAAAAACTTAATTCCGTAGAATAA

Upstream 100 bases:

>100_bases
TTTTATAATATATTTTAGGAAATAATTATAATATATGCTAATAAACTATACAATAATCTGATAAAATAATAGTATATAAC
AAAGGAAAGGGGATATATTT

Downstream 100 bases:

>100_bases
GAGAAAAGTGTAATCATTGGAGGTACTATATGGATAAGGTGGGATTAATACTAGAAGGTGGAGGTATGAGAGGACTTTAC
ACCGCAGGTATATTGGATTA

Product: phosphoglucomutase

Products: NA

Alternate protein names: PGM; Alpha-phosphoglucomutase; Glucose phosphomutase [H]

Number of amino acids: Translated: 573; Mature: 573

Protein sequence:

>573_residues
MNYMRIYNEWLNNDYFDDVTKEELKSIKDNPKEIEDRFYKNLEFGTAGLRGKIAAGTNRMNKYIIAKVTQGLANFIAKQG
KEVMNRGVAIAYDCRHYSDVFAKTAALVLAANGIKAYLFEDLRPTPELSYTVRRLNTISGIVVTASHNPKDYNGYKVYWE
DGAQILDKIAKPVTEEINNIKNFKEIKSISEEEALEKGLLEILGKEIDDEYIEKVKALSIRNDIDKDIKIVYTPLNGTGN
IPVRRVLRERRFTNVIVVPEQENPDPDFTTVGYPNPEDIKAFEYAKRLGEKERADLLLATDPDCDRLAVMARNNRGEFVA
LNGNQTGAVLIKYLVESKVEKGTLPEKPMIVKSVVTGDMGKVVGEKYGVTTFESLTGFKNICGKEMEMNKKGYNFIFGYE
ESIGYTAGDFVKDKDGVISAMFLCEAAAYYKTQGKTLIDVLNDMYNEFGYYRENLISLILEGVEGQRRIGRMMEAYRNEF
PKIIGDNKLIKYIDIDKGKEIDFITREEKSVEFPKSNVLKFILEDGSWYAIRPSGTEPKIKIYLYSKGHTLKDSEDKLKI
MEKTIMEKLNSVE

Sequences:

>Translated_573_residues
MNYMRIYNEWLNNDYFDDVTKEELKSIKDNPKEIEDRFYKNLEFGTAGLRGKIAAGTNRMNKYIIAKVTQGLANFIAKQG
KEVMNRGVAIAYDCRHYSDVFAKTAALVLAANGIKAYLFEDLRPTPELSYTVRRLNTISGIVVTASHNPKDYNGYKVYWE
DGAQILDKIAKPVTEEINNIKNFKEIKSISEEEALEKGLLEILGKEIDDEYIEKVKALSIRNDIDKDIKIVYTPLNGTGN
IPVRRVLRERRFTNVIVVPEQENPDPDFTTVGYPNPEDIKAFEYAKRLGEKERADLLLATDPDCDRLAVMARNNRGEFVA
LNGNQTGAVLIKYLVESKVEKGTLPEKPMIVKSVVTGDMGKVVGEKYGVTTFESLTGFKNICGKEMEMNKKGYNFIFGYE
ESIGYTAGDFVKDKDGVISAMFLCEAAAYYKTQGKTLIDVLNDMYNEFGYYRENLISLILEGVEGQRRIGRMMEAYRNEF
PKIIGDNKLIKYIDIDKGKEIDFITREEKSVEFPKSNVLKFILEDGSWYAIRPSGTEPKIKIYLYSKGHTLKDSEDKLKI
MEKTIMEKLNSVE
>Mature_573_residues
MNYMRIYNEWLNNDYFDDVTKEELKSIKDNPKEIEDRFYKNLEFGTAGLRGKIAAGTNRMNKYIIAKVTQGLANFIAKQG
KEVMNRGVAIAYDCRHYSDVFAKTAALVLAANGIKAYLFEDLRPTPELSYTVRRLNTISGIVVTASHNPKDYNGYKVYWE
DGAQILDKIAKPVTEEINNIKNFKEIKSISEEEALEKGLLEILGKEIDDEYIEKVKALSIRNDIDKDIKIVYTPLNGTGN
IPVRRVLRERRFTNVIVVPEQENPDPDFTTVGYPNPEDIKAFEYAKRLGEKERADLLLATDPDCDRLAVMARNNRGEFVA
LNGNQTGAVLIKYLVESKVEKGTLPEKPMIVKSVVTGDMGKVVGEKYGVTTFESLTGFKNICGKEMEMNKKGYNFIFGYE
ESIGYTAGDFVKDKDGVISAMFLCEAAAYYKTQGKTLIDVLNDMYNEFGYYRENLISLILEGVEGQRRIGRMMEAYRNEF
PKIIGDNKLIKYIDIDKGKEIDFITREEKSVEFPKSNVLKFILEDGSWYAIRPSGTEPKIKIYLYSKGHTLKDSEDKLKI
MEKTIMEKLNSVE

Specific function: Catalyzes the interconversion between glucose-6- phosphate and alpha-glucose-1-phosphate. This is the first step in the biosynthesis of diglucosyl-diacylglycerol (Glc2-DAG), i.e. the predominant glycolipid found in B.subtilis membrane, which is also used

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Homo sapiens, GI63055049, Length=555, Percent_Identity=32.6126126126126, Blast_Score=298, Evalue=9e-81,
Organism=Homo sapiens, GI31377548, Length=560, Percent_Identity=32.5, Blast_Score=262, Evalue=8e-70,
Organism=Escherichia coli, GI1789566, Length=266, Percent_Identity=30.0751879699248, Blast_Score=68, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71993870, Length=575, Percent_Identity=31.8260869565217, Blast_Score=251, Evalue=9e-67,
Organism=Caenorhabditis elegans, GI71993878, Length=313, Percent_Identity=34.8242811501597, Blast_Score=164, Evalue=2e-40,
Organism=Saccharomyces cerevisiae, GI6323934, Length=569, Percent_Identity=30.7557117750439, Blast_Score=241, Evalue=2e-64,
Organism=Drosophila melanogaster, GI20129809, Length=559, Percent_Identity=29.695885509839, Blast_Score=243, Evalue=2e-64,
Organism=Drosophila melanogaster, GI24653722, Length=583, Percent_Identity=28.8164665523156, Blast_Score=236, Evalue=5e-62,
Organism=Drosophila melanogaster, GI24651977, Length=432, Percent_Identity=31.9444444444444, Blast_Score=233, Evalue=3e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.2 [H]

Molecular weight: Translated: 65306; Mature: 65306

Theoretical pI: Translated: 5.61; Mature: 5.61

Prosite motif: PS00710 PGM_PMM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYMRIYNEWLNNDYFDDVTKEELKSIKDNPKEIEDRFYKNLEFGTAGLRGKIAAGTNRM
CCHHHHHHHHHCCCCCCCCCHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCEEECCCCHH
NKYIIAKVTQGLANFIAKQGKEVMNRGVAIAYDCRHYSDVFAKTAALVLAANGIKAYLFE
HHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHCCCCHHHHHHH
DLRPTPELSYTVRRLNTISGIVVTASHNPKDYNGYKVYWEDGAQILDKIAKPVTEEINNI
HCCCCCCHHHHHHHHHHCCEEEEEECCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHH
KNFKEIKSISEEEALEKGLLEILGKEIDDEYIEKVKALSIRNDIDKDIKIVYTPLNGTGN
HHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCC
IPVRRVLRERRFTNVIVVPEQENPDPDFTTVGYPNPEDIKAFEYAKRLGEKERADLLLAT
CHHHHHHHHHCCCEEEEEECCCCCCCCEEECCCCCHHHHHHHHHHHHCCCHHHCCEEEEC
DPDCDRLAVMARNNRGEFVALNGNQTGAVLIKYLVESKVEKGTLPEKPMIVKSVVTGDMG
CCCCCCEEEEEECCCCCEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCHH
KVVGEKYGVTTFESLTGFKNICGKEMEMNKKGYNFIFGYEESIGYTAGDFVKDKDGVISA
HHHHHHCCCCHHHHHHHHHHHCCCHHHCCCCCCEEEEEEHHCCCCCCCCCCCCCCHHHHH
MFLCEAAAYYKTQGKTLIDVLNDMYNEFGYYRENLISLILEGVEGQRRIGRMMEAYRNEF
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHC
PKIIGDNKLIKYIDIDKGKEIDFITREEKSVEFPKSNVLKFILEDGSWYAIRPSGTEPKI
CHHHCCCCEEEEEECCCCCCCCEEECCCCCCCCCHHHHHHHEEECCCEEEECCCCCCCEE
KIYLYSKGHTLKDSEDKLKIMEKTIMEKLNSVE
EEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNYMRIYNEWLNNDYFDDVTKEELKSIKDNPKEIEDRFYKNLEFGTAGLRGKIAAGTNRM
CCHHHHHHHHHCCCCCCCCCHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCEEECCCCHH
NKYIIAKVTQGLANFIAKQGKEVMNRGVAIAYDCRHYSDVFAKTAALVLAANGIKAYLFE
HHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHCCCCHHHHHHH
DLRPTPELSYTVRRLNTISGIVVTASHNPKDYNGYKVYWEDGAQILDKIAKPVTEEINNI
HCCCCCCHHHHHHHHHHCCEEEEEECCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHH
KNFKEIKSISEEEALEKGLLEILGKEIDDEYIEKVKALSIRNDIDKDIKIVYTPLNGTGN
HHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCC
IPVRRVLRERRFTNVIVVPEQENPDPDFTTVGYPNPEDIKAFEYAKRLGEKERADLLLAT
CHHHHHHHHHCCCEEEEEECCCCCCCCEEECCCCCHHHHHHHHHHHHCCCHHHCCEEEEC
DPDCDRLAVMARNNRGEFVALNGNQTGAVLIKYLVESKVEKGTLPEKPMIVKSVVTGDMG
CCCCCCEEEEEECCCCCEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCHH
KVVGEKYGVTTFESLTGFKNICGKEMEMNKKGYNFIFGYEESIGYTAGDFVKDKDGVISA
HHHHHHCCCCHHHHHHHHHHHCCCHHHCCCCCCEEEEEEHHCCCCCCCCCCCCCCHHHHH
MFLCEAAAYYKTQGKTLIDVLNDMYNEFGYYRENLISLILEGVEGQRRIGRMMEAYRNEF
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHC
PKIIGDNKLIKYIDIDKGKEIDFITREEKSVEFPKSNVLKFILEDGSWYAIRPSGTEPKI
CHHHCCCCEEEEEECCCCCCCCEEECCCCCCCCCHHHHHHHEEECCCEEEECCCCCCCEE
KIYLYSKGHTLKDSEDKLKIMEKTIMEKLNSVE
EEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377; 2127799 [H]