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The map label for this gene is ycbL [H]

Identifier: 28210332

GI number: 28210332

Start: 621634

End: 622338

Strand: Direct

Name: ycbL [H]

Synonym: CTC00597

Alternate gene names: 28210332

Gene position: 621634-622338 (Clockwise)

Preceding gene: 28210330

Following gene: 28210333

Centisome position: 22.21

GC content: 28.65

Gene sequence:

>705_bases
ATGAAGGAAAGAATATTAATAGTGGAAGACGATGAAGAAATAGCTTTATGTATAAAAGAATATGTAGAAAAAACAGGTTA
TGAAGTTTTGTGGGCATCCACAGGAAAAGAGGGATATGAAGAATTTAAGAGAGAAAATTTTAGTCTTTTAATGATAGATA
TTATGATGCCAGAAATGGACGGATTAACTCTTTGCAAAAATATAAGACTTACAAGTGATGTACCAATACTTATTATAAGT
GCTAAAAATGAAGATGGGTATAAAGTTAAAGGATTAAATATAGGTGCAGATGATTATATTACAAAACCATTTAGTCTAGT
AGAACTTCAAGCAAGGTTAGAATCTCATTTAAGAAGATATAGAAGATATAATGGAATAGAAAATAATGAACATATTTTAA
AGTTTAAAAGAGGTCTTATAATATACCAAGAAGGAAAATATGTAGAAGTGGATGGAAGAAACATTCATTTAACGTCAAAG
GAATTTGAACTACTAATGTTAATGGCTGAAAATCCTAAAAAAACCTTTACAAAAAGTGAACTCTACGAAATTTTATGGGG
AGAAAAGGATGTACATGGAAATAATACAGTTACTGTGCACATAAAAGAACTTAGAGAAAAGCTAAAAGAAAATATTAAAA
ATCCTAACTTTATAGAAACAGTATGGGGAGTAGGATACAAATTTATAGGAGAAGTGTTACCATGA

Upstream 100 bases:

>100_bases
TGAAAAAGTTACCTTTTTTCTTTAATTATAAAGAATTTATAAAGTTTTTAAAAACCATTATAATATAACCTATAATTTAA
CGTATAGGGAGGGCTTTTCT

Downstream 100 bases:

>100_bases
AAATTAAAAATTGGATTACAGTTTCCTATATAACAGTAATGCTCATACCTATTTTAACTGCTGTAATGTTGTTTTCTTGG
ATAAAAAATTATAATAGAAA

Product: two-component response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 234; Mature: 234

Protein sequence:

>234_residues
MKERILIVEDDEEIALCIKEYVEKTGYEVLWASTGKEGYEEFKRENFSLLMIDIMMPEMDGLTLCKNIRLTSDVPILIIS
AKNEDGYKVKGLNIGADDYITKPFSLVELQARLESHLRRYRRYNGIENNEHILKFKRGLIIYQEGKYVEVDGRNIHLTSK
EFELLMLMAENPKKTFTKSELYEILWGEKDVHGNNTVTVHIKELREKLKENIKNPNFIETVWGVGYKFIGEVLP

Sequences:

>Translated_234_residues
MKERILIVEDDEEIALCIKEYVEKTGYEVLWASTGKEGYEEFKRENFSLLMIDIMMPEMDGLTLCKNIRLTSDVPILIIS
AKNEDGYKVKGLNIGADDYITKPFSLVELQARLESHLRRYRRYNGIENNEHILKFKRGLIIYQEGKYVEVDGRNIHLTSK
EFELLMLMAENPKKTFTKSELYEILWGEKDVHGNNTVTVHIKELREKLKENIKNPNFIETVWGVGYKFIGEVLP
>Mature_234_residues
MKERILIVEDDEEIALCIKEYVEKTGYEVLWASTGKEGYEEFKRENFSLLMIDIMMPEMDGLTLCKNIRLTSDVPILIIS
AKNEDGYKVKGLNIGADDYITKPFSLVELQARLESHLRRYRRYNGIENNEHILKFKRGLIIYQEGKYVEVDGRNIHLTSK
EFELLMLMAENPKKTFTKSELYEILWGEKDVHGNNTVTVHIKELREKLKENIKNPNFIETVWGVGYKFIGEVLP

Specific function: Member of the two-component regulatory system ycbM/ycbL [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788394, Length=226, Percent_Identity=34.9557522123894, Blast_Score=144, Evalue=7e-36,
Organism=Escherichia coli, GI1789809, Length=234, Percent_Identity=32.0512820512821, Blast_Score=136, Evalue=1e-33,
Organism=Escherichia coli, GI1786911, Length=225, Percent_Identity=31.1111111111111, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI1789402, Length=227, Percent_Identity=34.3612334801762, Blast_Score=129, Evalue=1e-31,
Organism=Escherichia coli, GI87082012, Length=227, Percent_Identity=30.3964757709251, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI1786599, Length=231, Percent_Identity=29.4372294372294, Blast_Score=114, Evalue=5e-27,
Organism=Escherichia coli, GI1790863, Length=231, Percent_Identity=29.8701298701299, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1786784, Length=224, Percent_Identity=31.6964285714286, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI2367329, Length=229, Percent_Identity=29.6943231441048, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1790860, Length=230, Percent_Identity=27.3913043478261, Blast_Score=107, Evalue=6e-25,
Organism=Escherichia coli, GI1790552, Length=232, Percent_Identity=31.8965517241379, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1787229, Length=235, Percent_Identity=28.936170212766, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI145693140, Length=231, Percent_Identity=29.4372294372294, Blast_Score=91, Evalue=5e-20,
Organism=Escherichia coli, GI1787375, Length=228, Percent_Identity=28.5087719298246, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1790437, Length=114, Percent_Identity=35.0877192982456, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1788550, Length=107, Percent_Identity=33.6448598130841, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27341; Mature: 27341

Theoretical pI: Translated: 5.49; Mature: 5.49

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKERILIVEDDEEIALCIKEYVEKTGYEVLWASTGKEGYEEFKRENFSLLMIDIMMPEMD
CCCCEEEEECCCHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHCCCEEEEEEEECCCCC
GLTLCKNIRLTSDVPILIISAKNEDGYKVKGLNIGADDYITKPFSLVELQARLESHLRRY
CCCHHHCCEECCCCCEEEEEECCCCCCEEEEEEECCCCHHCCCHHHHHHHHHHHHHHHHH
RRYNGIENNEHILKFKRGLIIYQEGKYVEVDGRNIHLTSKEFELLMLMAENPKKTFTKSE
HHHCCCCCCCCEEEEECCEEEEECCCEEEECCCEEEEECCCEEEEEEEECCCCHHHHHHH
LYEILWGEKDVHGNNTVTVHIKELREKLKENIKNPNFIETVWGVGYKFIGEVLP
HHHHHCCCCCCCCCCEEEEEHHHHHHHHHHHCCCCCHHHHHHHCHHHHHHHCCC
>Mature Secondary Structure
MKERILIVEDDEEIALCIKEYVEKTGYEVLWASTGKEGYEEFKRENFSLLMIDIMMPEMD
CCCCEEEEECCCHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHCCCEEEEEEEECCCCC
GLTLCKNIRLTSDVPILIISAKNEDGYKVKGLNIGADDYITKPFSLVELQARLESHLRRY
CCCHHHCCEECCCCCEEEEEECCCCCCEEEEEEECCCCHHCCCHHHHHHHHHHHHHHHHH
RRYNGIENNEHILKFKRGLIIYQEGKYVEVDGRNIHLTSKEFELLMLMAENPKKTFTKSE
HHHCCCCCCCCEEEEECCEEEEECCCEEEECCCEEEEECCCEEEEEEEECCCCHHHHHHH
LYEILWGEKDVHGNNTVTVHIKELREKLKENIKNPNFIETVWGVGYKFIGEVLP
HHHHHCCCCCCCCCCEEEEEHHHHHHHHHHHCCCCCHHHHHHHCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7704254; 9384377 [H]