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The map label for this gene is 28210330

Identifier: 28210330

GI number: 28210330

Start: 619004

End: 620275

Strand: Direct

Name: 28210330

Synonym: CTC00595

Alternate gene names: NA

Gene position: 619004-620275 (Clockwise)

Preceding gene: 28210324

Following gene: 28210332

Centisome position: 22.11

GC content: 31.76

Gene sequence:

>1272_bases
ATGGAGTTATTAAAACTAGGGAGTAGAGGCCCTAGAGTAAGGGAAGTCCAATCAATATTAAAACAAATGGGATATTATAG
AGGAACGGTTGATGGGATATATGGATCTCAAACTGAAGCTGCGGTAAGGAATTTTCAAAAAAATATGGGGCTTATAGCTG
ATGGAATAGTAGGAGAAAATACTTATAGAGCTTTAGGAAGATATTTATCAGGATATGATGTATACACCATCAGACCTGGA
GATACATTTTACAAAATAGCTAAAAAATATAATACAAATTTATATAGTATATTATTAGCAAACCCTAATATAGATCCCTA
TAATTTACAGGTAGGCAATGAAATAATAGTACCTTATGGTATACCAGTAGTTCAAACAGATATTGATTATACTTATGAAA
TATTAGAAAGAGATATTAATGGCTTAAAAAGAAGATATCCCTTTATAGAAGTAGGTTCCATAGGAAAAAGTGTTTTAGGA
AGAGAGCTTTATTATTTAAAACTAGGAAATGGTCCTAATAAAGTTTTTTATAATGGAGCACATCATTCTTTAGAATGGAT
TACTACACCTCTTCTTATGAAGTTTGCTGAAAACTTTATAAGAAGTTATGCCTTTGGAGAAGAAATGAGAGGGTATAATA
TAGGAGATATATGGAGTAGAAGTACAATATATATAGTGCCTATGGTTAATCCAGATGGAGTGGATCTAGTTTTAAATGGC
TTAAAAAGAGACAATCCATATTATGATGAGTTAATAGTATGGAATAATGGAAGTACAGATTTTTCAACAAATTGGCAAGC
AAATAATAGAGGAGTAGATTTAAATCATAATTACAATGCTTCTTGGCAAAAATCTAAAGATGCTGAAAAAGAATATGGAA
TATATGGTCCAGGACCTACAAGGTATTCAGGACCATATCCAGAATCAGAGCCAGAAACTCAGGCTATGGTTAAATTTACT
AGAGAACATGACTTTAGATTAACACTAGCATATCATAGTCAAGGCGAGGTAATATACTGGCAATATAGCACATTAACACC
TCCAGAATCAGAAAGAATAGTAGAAATTTTTGCAGAAGTAAGCGGTTATACGCCAAGTCAAACGGAAGGAATAGCCTCAT
ATGCAGGCTATAAAGATTGGTTTATTGAAGAATTTAGAAGACCTGGTTTTACTATAGAAGTAGGACTTGGTAAAAATCCA
CTACCTATAAGTCAGTTTGATAAAATTTATGAAGATAATGAAGAACTTTTATTAATAGCATCGGTTATTTAA

Upstream 100 bases:

>100_bases
AAAAACAAGTAAAATGTTGAATTTGCGTAGAATAATTTATTCACATAATTATAACTATAAAATAAAATGTTAATGGAACA
ATAAATAGGCAGGTTGTTAT

Downstream 100 bases:

>100_bases
AAAATAGCAGTACATTTTTTATGTACTGCTACTTTATAATTAACATAAATTTTTATATTGAAGCCCTAATTTATTAGCTA
CCAAAATAGCATTATATAGT

Product: gamma-D-glutamyl-L-diamino acid endopeptidase I

Products: NA

Alternate protein names: Endopeptidase I; Gamma-D-glutamyl-L-diamino acid endopeptidase I; Gamma-D-glutamyl-meso-diaminopimelate peptidase I [H]

Number of amino acids: Translated: 423; Mature: 423

Protein sequence:

>423_residues
MELLKLGSRGPRVREVQSILKQMGYYRGTVDGIYGSQTEAAVRNFQKNMGLIADGIVGENTYRALGRYLSGYDVYTIRPG
DTFYKIAKKYNTNLYSILLANPNIDPYNLQVGNEIIVPYGIPVVQTDIDYTYEILERDINGLKRRYPFIEVGSIGKSVLG
RELYYLKLGNGPNKVFYNGAHHSLEWITTPLLMKFAENFIRSYAFGEEMRGYNIGDIWSRSTIYIVPMVNPDGVDLVLNG
LKRDNPYYDELIVWNNGSTDFSTNWQANNRGVDLNHNYNASWQKSKDAEKEYGIYGPGPTRYSGPYPESEPETQAMVKFT
REHDFRLTLAYHSQGEVIYWQYSTLTPPESERIVEIFAEVSGYTPSQTEGIASYAGYKDWFIEEFRRPGFTIEVGLGKNP
LPISQFDKIYEDNEELLLIASVI

Sequences:

>Translated_423_residues
MELLKLGSRGPRVREVQSILKQMGYYRGTVDGIYGSQTEAAVRNFQKNMGLIADGIVGENTYRALGRYLSGYDVYTIRPG
DTFYKIAKKYNTNLYSILLANPNIDPYNLQVGNEIIVPYGIPVVQTDIDYTYEILERDINGLKRRYPFIEVGSIGKSVLG
RELYYLKLGNGPNKVFYNGAHHSLEWITTPLLMKFAENFIRSYAFGEEMRGYNIGDIWSRSTIYIVPMVNPDGVDLVLNG
LKRDNPYYDELIVWNNGSTDFSTNWQANNRGVDLNHNYNASWQKSKDAEKEYGIYGPGPTRYSGPYPESEPETQAMVKFT
REHDFRLTLAYHSQGEVIYWQYSTLTPPESERIVEIFAEVSGYTPSQTEGIASYAGYKDWFIEEFRRPGFTIEVGLGKNP
LPISQFDKIYEDNEELLLIASVI
>Mature_423_residues
MELLKLGSRGPRVREVQSILKQMGYYRGTVDGIYGSQTEAAVRNFQKNMGLIADGIVGENTYRALGRYLSGYDVYTIRPG
DTFYKIAKKYNTNLYSILLANPNIDPYNLQVGNEIIVPYGIPVVQTDIDYTYEILERDINGLKRRYPFIEVGSIGKSVLG
RELYYLKLGNGPNKVFYNGAHHSLEWITTPLLMKFAENFIRSYAFGEEMRGYNIGDIWSRSTIYIVPMVNPDGVDLVLNG
LKRDNPYYDELIVWNNGSTDFSTNWQANNRGVDLNHNYNASWQKSKDAEKEYGIYGPGPTRYSGPYPESEPETQAMVKFT
REHDFRLTLAYHSQGEVIYWQYSTLTPPESERIVEIFAEVSGYTPSQTEGIASYAGYKDWFIEEFRRPGFTIEVGLGKNP
LPISQFDKIYEDNEELLLIASVI

Specific function: An endopeptidase which hydrolyzes the gamma-D-Glu- (L)meso-diaminopimelic acid bond of L-Ala-gamma-D-Glu-(L)meso- diaminopimelic acid and L-Ala-gamma-D-Glu-(L)meso-diaminopimelic acid(L)-D-Ala peptides. It is active on spore cortex peptidoglycan [H]

COG id: COG2866

COG function: function code E; Predicted carboxypeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 2 LysM repeats [H]

Homologues:

Organism=Homo sapiens, GI188536067, Length=201, Percent_Identity=28.3582089552239, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI221316749, Length=222, Percent_Identity=25.6756756756757, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI54607080, Length=288, Percent_Identity=24.3055555555556, Blast_Score=69, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24639964, Length=232, Percent_Identity=26.2931034482759, Blast_Score=66, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000834
- InterPro:   IPR018392
- InterPro:   IPR002482 [H]

Pfam domain/function: PF01476 LysM; PF00246 Peptidase_M14 [H]

EC number: =3.4.19.11 [H]

Molecular weight: Translated: 48366; Mature: 48366

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: PS50008 PIPLC_Y_DOMAIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELLKLGSRGPRVREVQSILKQMGYYRGTVDGIYGSQTEAAVRNFQKNMGLIADGIVGEN
CCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCEEECCCCCCH
TYRALGRYLSGYDVYTIRPGDTFYKIAKKYNTNLYSILLANPNIDPYNLQVGNEIIVPYG
HHHHHHHHHCCCEEEEECCCCHHHHHHHHHCCCEEEEEEECCCCCCEEEEECCEEEEECC
IPVVQTDIDYTYEILERDINGLKRRYPFIEVGSIGKSVLGRELYYLKLGNGPNKVFYNGA
CEEEEECCHHHHHHHHHHHHHHHHHCCEEEECCCCHHHHCCEEEEEEECCCCCEEEECCC
HHSLEWITTPLLMKFAENFIRSYAFGEEMRGYNIGDIWSRSTIYIVPMVNPDGVDLVLNG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCHHHHHHH
LKRDNPYYDELIVWNNGSTDFSTNWQANNRGVDLNHNYNASWQKSKDAEKEYGIYGPGPT
HCCCCCCCCEEEEECCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCHHHCCCCCCCCC
RYSGPYPESEPETQAMVKFTREHDFRLTLAYHSQGEVIYWQYSTLTPPESERIVEIFAEV
CCCCCCCCCCCCHHHHHHHHCCCCEEEEEEEECCCCEEEEEECCCCCCCHHHHHHHHHHH
SGYTPSQTEGIASYAGYKDWFIEEFRRPGFTIEVGLGKNPLPISQFDKIYEDNEELLLIA
CCCCCCCCCCHHHHCCCHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHCCCCCEEEEE
SVI
ECC
>Mature Secondary Structure
MELLKLGSRGPRVREVQSILKQMGYYRGTVDGIYGSQTEAAVRNFQKNMGLIADGIVGEN
CCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCEEECCCCCCH
TYRALGRYLSGYDVYTIRPGDTFYKIAKKYNTNLYSILLANPNIDPYNLQVGNEIIVPYG
HHHHHHHHHCCCEEEEECCCCHHHHHHHHHCCCEEEEEEECCCCCCEEEEECCEEEEECC
IPVVQTDIDYTYEILERDINGLKRRYPFIEVGSIGKSVLGRELYYLKLGNGPNKVFYNGA
CEEEEECCHHHHHHHHHHHHHHHHHCCEEEECCCCHHHHCCEEEEEEECCCCCEEEECCC
HHSLEWITTPLLMKFAENFIRSYAFGEEMRGYNIGDIWSRSTIYIVPMVNPDGVDLVLNG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCHHHHHHH
LKRDNPYYDELIVWNNGSTDFSTNWQANNRGVDLNHNYNASWQKSKDAEKEYGIYGPGPT
HCCCCCCCCEEEEECCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCHHHCCCCCCCCC
RYSGPYPESEPETQAMVKFTREHDFRLTLAYHSQGEVIYWQYSTLTPPESERIVEIFAEV
CCCCCCCCCCCCHHHHHHHHCCCCEEEEEEEECCCCEEEEEECCCCCCCHHHHHHHHHHH
SGYTPSQTEGIASYAGYKDWFIEEFRRPGFTIEVGLGKNPLPISQFDKIYEDNEELLLIA
CCCCCCCCCCHHHHCCCHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHCCCCCEEEEE
SVI
ECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8503890; 3922755 [H]