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The map label for this gene is cat2 [H]

Identifier: 28210230

GI number: 28210230

Start: 487490

End: 488803

Strand: Direct

Name: cat2 [H]

Synonym: CTC00482

Alternate gene names: 28210230

Gene position: 487490-488803 (Clockwise)

Preceding gene: 28210229

Following gene: 28210231

Centisome position: 17.42

GC content: 31.58

Gene sequence:

>1314_bases
ATGAATTGGGAAGATATTTACAAAAGTAAGCTATTATCATCAAAGGAAGCTGTTTTAAAATTAAAATCTGAAAACCACGT
AGCAGTTGGACATGCTGCTAGTGAACCTAGACTTTTAATGAAAGCTTTAGTTGATAATAAGGAAAGTTTTAGAGATTTAA
AACTTTATCAAATGATAGCTTTAGAAAAGAGTGAATGTGCTAAAAAAGGTATGGAAAAACATTTTAGTTATAATTCTCTT
TTTGTAGGAGGAGGGAGTAGGGAAGCTATAAATGATGGAAGAGCTGATTATATTCCTTGTTTTTTTTCAAGGATACCAAG
ACTTTTTAGAGAGAACTATATAAAATTAGATGCGGCATTAATACAAGTTGCACCTCCAGATGAGCATGGATTTTGTAGCT
TTGGTGTTTCTTCTGATTATATAAAACCTGCAGCAGAATGTGCAAAACTTGTTATTGCAGAAGTAAATGATAAGATGCCA
AGAACTTTAGGGGATAATTTTATACATGTTAGTGACATAGATTATATAGTTGAAAATTCTCGAGAGATACCAGAGCTAAA
ACCTTCTAATATAGGTGATATAGAAAGGGCAATAGGAGAAAATTGTGCATCTCTTATAAATAATGGAGATGTTTTGCAAT
TGGGCATAGGTGCAATTCCAGATGCAGTACTTTTATTTTTAAAGGATAAAAAGGATTTAGGAATACATTCAGAGATGATT
TCTGATGGGGTGGTAGATTTAGTAAAGGCAGGGGTAATAAATAATAAGAAAAAGACTTTGCATCAAGGGAAGATAATTGT
TAGTTTTTTAATGGGAACAAAGAAATTATATGATTTTGTGGATAATAATCCTATGGTGAGAATGTACCCTGTGGATTATG
TTAATAATCCTGTAGTTATTAGTAAAAATGATAATATGGTCTCTATAAATTCCTGTATTCAAATAGATCTTATGGGTCAA
ATAGATGCAGAAACCATAGGCTTTACCCAAATAAGTGGTGTTGGTGGACAAATAGATTTTATAAGAGGAGCAGGTCTTAG
TAAAAATGGAAGGTCTATCATTGCAATACCTTCTACTGTAGGAAATGGAAAAATATCTAAAATAGTTCCTCTATTAGATA
AAGGAGCAGCAGTAACTACCACAAGAAATGAAGTGGATTATGTAGTTACTGAATACGGAATTGCAAGACTTAAAGGTAAA
AATTTAAGGGACAGGGCCCGAGAACTTATTAAAATAGCTCATCCTGATTTTAGAGAGGAATTAAAATTAGAATATAAGAA
TAGATTTAAAGAAGAGTTTAAAAGAATAGGATAA

Upstream 100 bases:

>100_bases
ATCCTGTATTCTAAAGAATAAGAAAGGGGAATTAGATGAATACACTTAGAACTTAGCTCAACATTGATTAAGTATTAACA
ATTAAATAGGGGGAATTGAG

Downstream 100 bases:

>100_bases
ATACTAGTAAATAGGAGCTGTTATATTAGTGATTTTTTAAATCGCTATTAACAGCTCTTTTTTTTAAGAAAATATTAAGG
TTTAATTAATGTGTTATTCA

Product: 4-hydroxybutyrate coenzyme A transferase

Products: propionate; succinyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 437; Mature: 437

Protein sequence:

>437_residues
MNWEDIYKSKLLSSKEAVLKLKSENHVAVGHAASEPRLLMKALVDNKESFRDLKLYQMIALEKSECAKKGMEKHFSYNSL
FVGGGSREAINDGRADYIPCFFSRIPRLFRENYIKLDAALIQVAPPDEHGFCSFGVSSDYIKPAAECAKLVIAEVNDKMP
RTLGDNFIHVSDIDYIVENSREIPELKPSNIGDIERAIGENCASLINNGDVLQLGIGAIPDAVLLFLKDKKDLGIHSEMI
SDGVVDLVKAGVINNKKKTLHQGKIIVSFLMGTKKLYDFVDNNPMVRMYPVDYVNNPVVISKNDNMVSINSCIQIDLMGQ
IDAETIGFTQISGVGGQIDFIRGAGLSKNGRSIIAIPSTVGNGKISKIVPLLDKGAAVTTTRNEVDYVVTEYGIARLKGK
NLRDRARELIKIAHPDFREELKLEYKNRFKEEFKRIG

Sequences:

>Translated_437_residues
MNWEDIYKSKLLSSKEAVLKLKSENHVAVGHAASEPRLLMKALVDNKESFRDLKLYQMIALEKSECAKKGMEKHFSYNSL
FVGGGSREAINDGRADYIPCFFSRIPRLFRENYIKLDAALIQVAPPDEHGFCSFGVSSDYIKPAAECAKLVIAEVNDKMP
RTLGDNFIHVSDIDYIVENSREIPELKPSNIGDIERAIGENCASLINNGDVLQLGIGAIPDAVLLFLKDKKDLGIHSEMI
SDGVVDLVKAGVINNKKKTLHQGKIIVSFLMGTKKLYDFVDNNPMVRMYPVDYVNNPVVISKNDNMVSINSCIQIDLMGQ
IDAETIGFTQISGVGGQIDFIRGAGLSKNGRSIIAIPSTVGNGKISKIVPLLDKGAAVTTTRNEVDYVVTEYGIARLKGK
NLRDRARELIKIAHPDFREELKLEYKNRFKEEFKRIG
>Mature_437_residues
MNWEDIYKSKLLSSKEAVLKLKSENHVAVGHAASEPRLLMKALVDNKESFRDLKLYQMIALEKSECAKKGMEKHFSYNSL
FVGGGSREAINDGRADYIPCFFSRIPRLFRENYIKLDAALIQVAPPDEHGFCSFGVSSDYIKPAAECAKLVIAEVNDKMP
RTLGDNFIHVSDIDYIVENSREIPELKPSNIGDIERAIGENCASLINNGDVLQLGIGAIPDAVLLFLKDKKDLGIHSEMI
SDGVVDLVKAGVINNKKKTLHQGKIIVSFLMGTKKLYDFVDNNPMVRMYPVDYVNNPVVISKNDNMVSINSCIQIDLMGQ
IDAETIGFTQISGVGGQIDFIRGAGLSKNGRSIIAIPSTVGNGKISKIVPLLDKGAAVTTTRNEVDYVVTEYGIARLKGK
NLRDRARELIKIAHPDFREELKLEYKNRFKEEFKRIG

Specific function: Unknown

COG id: COG0427

COG function: function code C; Acetyl-CoA hydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetyl-CoA hydrolase/transferase family [H]

Homologues:

Organism=Escherichia coli, GI1789287, Length=222, Percent_Identity=29.7297297297297, Blast_Score=79, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI32563853, Length=429, Percent_Identity=46.1538461538462, Blast_Score=371, Evalue=1e-103,
Organism=Caenorhabditis elegans, GI17538151, Length=433, Percent_Identity=42.7251732101617, Blast_Score=338, Evalue=3e-93,
Organism=Saccharomyces cerevisiae, GI6319456, Length=419, Percent_Identity=26.2529832935561, Blast_Score=80, Evalue=8e-16,
Organism=Drosophila melanogaster, GI21358615, Length=431, Percent_Identity=46.6357308584687, Blast_Score=384, Evalue=1e-107,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003702 [H]

Pfam domain/function: PF02550 AcetylCoA_hydro [H]

EC number: NA

Molecular weight: Translated: 48586; Mature: 48586

Theoretical pI: Translated: 8.11; Mature: 8.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNWEDIYKSKLLSSKEAVLKLKSENHVAVGHAASEPRLLMKALVDNKESFRDLKLYQMIA
CCHHHHHHHHHHCCCHHHEEECCCCEEEEECCCCCHHHHHHHHHCCHHHHHHHHHHHHHH
LEKSECAKKGMEKHFSYNSLFVGGGSREAINDGRADYIPCFFSRIPRLFRENYIKLDAAL
HCHHHHHHHHHHHHCCCCEEEECCCCCHHCCCCCCCHHHHHHHHHHHHHHHCCEEEEEEE
IQVAPPDEHGFCSFGVSSDYIKPAAECAKLVIAEVNDKMPRTLGDNFIHVSDIDYIVENS
EEECCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHCCCCCHHHCCCEEEECCHHHHHHCC
REIPELKPSNIGDIERAIGENCASLINNGDVLQLGIGAIPDAVLLFLKDKKDLGIHSEMI
CCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEECCCCCCCHHEEEEECCCCCCHHHHHH
SDGVVDLVKAGVINNKKKTLHQGKIIVSFLMGTKKLYDFVDNNPMVRMYPVDYVNNPVVI
HHHHHHHHHHCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEE
SKNDNMVSINSCIQIDLMGQIDAETIGFTQISGVGGQIDFIRGAGLSKNGRSIIAIPSTV
ECCCCEEEECCEEEEEEECCCCCCCCCCEEECCCCCEEEEEECCCCCCCCCEEEEECCCC
GNGKISKIVPLLDKGAAVTTTRNEVDYVVTEYGIARLKGKNLRDRARELIKIAHPDFREE
CCCCHHHHHHHHCCCCEEEEECCCCCEEEEHHCHHHHCCCCHHHHHHHHHHHCCCCHHHH
LKLEYKNRFKEEFKRIG
HHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNWEDIYKSKLLSSKEAVLKLKSENHVAVGHAASEPRLLMKALVDNKESFRDLKLYQMIA
CCHHHHHHHHHHCCCHHHEEECCCCEEEEECCCCCHHHHHHHHHCCHHHHHHHHHHHHHH
LEKSECAKKGMEKHFSYNSLFVGGGSREAINDGRADYIPCFFSRIPRLFRENYIKLDAAL
HCHHHHHHHHHHHHCCCCEEEECCCCCHHCCCCCCCHHHHHHHHHHHHHHHCCEEEEEEE
IQVAPPDEHGFCSFGVSSDYIKPAAECAKLVIAEVNDKMPRTLGDNFIHVSDIDYIVENS
EEECCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHCCCCCHHHCCCEEEECCHHHHHHCC
REIPELKPSNIGDIERAIGENCASLINNGDVLQLGIGAIPDAVLLFLKDKKDLGIHSEMI
CCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEECCCCCCCHHEEEEECCCCCCHHHHHH
SDGVVDLVKAGVINNKKKTLHQGKIIVSFLMGTKKLYDFVDNNPMVRMYPVDYVNNPVVI
HHHHHHHHHHCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEE
SKNDNMVSINSCIQIDLMGQIDAETIGFTQISGVGGQIDFIRGAGLSKNGRSIIAIPSTV
ECCCCEEEECCEEEEEEECCCCCCCCCCEEECCCCCEEEEEECCCCCCCCCEEEEECCCC
GNGKISKIVPLLDKGAAVTTTRNEVDYVVTEYGIARLKGKNLRDRARELIKIAHPDFREE
CCCCHHHHHHHHCCCCEEEEECCCCCEEEEHHCHHHHCCCCHHHHHHHHHHHCCCCHHHH
LKLEYKNRFKEEFKRIG
HHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: propionyl-CoA; succinate [C]

Specific reaction: propionyl-CoA + succinate = propionate + succinyl-CoA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550525 [H]