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The map label for this gene is vanW [H]

Identifier: 28210116

GI number: 28210116

Start: 345402

End: 346805

Strand: Direct

Name: vanW [H]

Synonym: CTC00360

Alternate gene names: 28210116

Gene position: 345402-346805 (Clockwise)

Preceding gene: 28210115

Following gene: 28210117

Centisome position: 12.34

GC content: 27.07

Gene sequence:

>1404_bases
GTGCTTATATTAGGAGGTGAAATTATGGCAAAAAGAAAAAAAAGAAAGAAAAATTCAAGTAAAAAAATTACTATATGTTT
AATAATAGCTGCAGTATTAATAGGGTTAACTTCCGTAAAAGCAGGGTATAGCTATAATAATATAAAACATTATGAGAATT
TATTTTATCCGGGTATTACAGTTGGCAATGAGGATATTTCAGGTAAAACTTTAGAAGAAGGTAGAAAAATTATAAAAGAA
AAATATGCAAATAAGTTGCTAAATAAAAAGATAACTGTAAAGATTCCAGAAGGTGAATATTCAATAACCTTTGATAAGAT
AGAGGGAAAATACGATATAGATAACTCGTTAAAAAAAGCTTATGACTATGGTAAAGATTCTAATGCATTTTCTAAATATA
GAATAATAAAAAAAGCAGAAAAAAAACCTTTCGAACTTATGTTTTCTTATAATGAAAAAAAAGTAATTGATTTTATTAAT
GATGTAGAAAAAAAAGTAAATAAAGATGCAACTAATGCAAAACTTATAAAGAAAGGCGAAAATTTTAATATAATTCCAGA
AAGTGTGGGAAAAAAACTAAATAAAGAGAAATTACAAAAAGATATATTAACTAATATAAATGGTGATATCTCTAAAGATT
TAGTTGTAAATGGGGAAGTGAAAAATGTACAAGCTAAGGTTACTTCTGATAAATTAACATCAGTGAATAGTTTAATTGCT
TCTTTTGGAACTAATTATGCAAATATATCTTCACAGCAAAGAGCAAATAATATAAGACTTAGTACGGAAAGTATAAATGG
TACTGTGTTAATGCCAGGAGAAGTATTTAGTTTTAATGGAGCAGTAGGAGAAAGAACTGCTGATAGAGGATATCAAGCGG
CATCAGTAATTATAGGTAATCAAGTAGAAGATGGTCTTGGTGGAGGTATATGTCAAACTTCATCCACTTTATACAATGCA
GCTCTTAAGGCTAACTTAAAATCAGTGGAAAGAGCACATCATACTTTACCATCAAGTTATGTACCTTTAGGAAGAGATGC
TACAGTAGATTGGGAAAATATAGATTATAAATTTAGAAATGACTACTCTTTTCCTATATATATAGAAGGATTAACTCAAA
ATGGAGAGGTCAGATTTAATATATATTCACATTCTTCTGTTAAAAATAGAAGGTATGAAATAACTACAGATGTATATGAA
AATCTACCAACTGATACAAAAACAATACAAGATGCAAATTTATCAAAAGGCACAACAGAAGTAGTTCAGAAGCCTTATCA
AGGATTTAAAGTTAAAGTTTATAGAAATATATATGAAAATGAAAAATTTATAAATAAAGAACTTATTTCAAATGATTTTT
ATAGGCCTATACAGGGAATAATAAAAGTAGGTACTAAAAAATAA

Upstream 100 bases:

>100_bases
AATCAACTAGTGGAATAATTGGGTAAACGTGGGTTAATTTAAATCATAAATTATTTTAAGAAATATTGTTTATAATTTTA
ATTAAAGCTATAATGAATAT

Downstream 100 bases:

>100_bases
TATAGAGGAGTTGGAGGAGAAAAATCTCTTTTCAACTCTTCTACTTTTACTAGGGAAAGGGGAAAATATTTTGAGAGAAA
CAGAAATTGTGGAAAAAATT

Product: vancomycin b-type resistance protein vanW

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 467; Mature: 467

Protein sequence:

>467_residues
MLILGGEIMAKRKKRKKNSSKKITICLIIAAVLIGLTSVKAGYSYNNIKHYENLFYPGITVGNEDISGKTLEEGRKIIKE
KYANKLLNKKITVKIPEGEYSITFDKIEGKYDIDNSLKKAYDYGKDSNAFSKYRIIKKAEKKPFELMFSYNEKKVIDFIN
DVEKKVNKDATNAKLIKKGENFNIIPESVGKKLNKEKLQKDILTNINGDISKDLVVNGEVKNVQAKVTSDKLTSVNSLIA
SFGTNYANISSQQRANNIRLSTESINGTVLMPGEVFSFNGAVGERTADRGYQAASVIIGNQVEDGLGGGICQTSSTLYNA
ALKANLKSVERAHHTLPSSYVPLGRDATVDWENIDYKFRNDYSFPIYIEGLTQNGEVRFNIYSHSSVKNRRYEITTDVYE
NLPTDTKTIQDANLSKGTTEVVQKPYQGFKVKVYRNIYENEKFINKELISNDFYRPIQGIIKVGTKK

Sequences:

>Translated_467_residues
MLILGGEIMAKRKKRKKNSSKKITICLIIAAVLIGLTSVKAGYSYNNIKHYENLFYPGITVGNEDISGKTLEEGRKIIKE
KYANKLLNKKITVKIPEGEYSITFDKIEGKYDIDNSLKKAYDYGKDSNAFSKYRIIKKAEKKPFELMFSYNEKKVIDFIN
DVEKKVNKDATNAKLIKKGENFNIIPESVGKKLNKEKLQKDILTNINGDISKDLVVNGEVKNVQAKVTSDKLTSVNSLIA
SFGTNYANISSQQRANNIRLSTESINGTVLMPGEVFSFNGAVGERTADRGYQAASVIIGNQVEDGLGGGICQTSSTLYNA
ALKANLKSVERAHHTLPSSYVPLGRDATVDWENIDYKFRNDYSFPIYIEGLTQNGEVRFNIYSHSSVKNRRYEITTDVYE
NLPTDTKTIQDANLSKGTTEVVQKPYQGFKVKVYRNIYENEKFINKELISNDFYRPIQGIIKVGTKK
>Mature_467_residues
MLILGGEIMAKRKKRKKNSSKKITICLIIAAVLIGLTSVKAGYSYNNIKHYENLFYPGITVGNEDISGKTLEEGRKIIKE
KYANKLLNKKITVKIPEGEYSITFDKIEGKYDIDNSLKKAYDYGKDSNAFSKYRIIKKAEKKPFELMFSYNEKKVIDFIN
DVEKKVNKDATNAKLIKKGENFNIIPESVGKKLNKEKLQKDILTNINGDISKDLVVNGEVKNVQAKVTSDKLTSVNSLIA
SFGTNYANISSQQRANNIRLSTESINGTVLMPGEVFSFNGAVGERTADRGYQAASVIIGNQVEDGLGGGICQTSSTLYNA
ALKANLKSVERAHHTLPSSYVPLGRDATVDWENIDYKFRNDYSFPIYIEGLTQNGEVRFNIYSHSSVKNRRYEITTDVYE
NLPTDTKTIQDANLSKGTTEVVQKPYQGFKVKVYRNIYENEKFINKELISNDFYRPIQGIIKVGTKK

Specific function: Unknown

COG id: COG2720

COG function: function code V; Uncharacterized vancomycin resistance protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022029
- InterPro:   IPR007391 [H]

Pfam domain/function: PF12229 PG_binding_4; PF04294 VanW [H]

EC number: NA

Molecular weight: Translated: 52552; Mature: 52552

Theoretical pI: Translated: 9.93; Mature: 9.93

Prosite motif: PS51109 G5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLILGGEIMAKRKKRKKNSSKKITICLIIAAVLIGLTSVKAGYSYNNIKHYENLFYPGIT
CEEECCHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCEE
VGNEDISGKTLEEGRKIIKEKYANKLLNKKITVKIPEGEYSITFDKIEGKYDIDNSLKKA
ECCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEECCCCEEEEEECCCCCCCCCHHHHHH
YDYGKDSNAFSKYRIIKKAEKKPFELMFSYNEKKVIDFINDVEKKVNKDATNAKLIKKGE
HCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCCCHHEECCC
NFNIIPESVGKKLNKEKLQKDILTNINGDISKDLVVNGEVKNVQAKVTSDKLTSVNSLIA
CCCCCCHHHHHHCCHHHHHHHHHHCCCCCCCCCEEECCCCCCEEEEECHHHHHHHHHHHH
SFGTNYANISSQQRANNIRLSTESINGTVLMPGEVFSFNGAVGERTADRGYQAASVIIGN
HHCCCCCCCCHHHHCCCEEEEEECCCCEEEECCCEEEECCCCCCCCHHCCCCEEEEEECC
QVEDGLGGGICQTSSTLYNAALKANLKSVERAHHTLPSSYVPLGRDATVDWENIDYKFRN
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEECCCCCCEEECC
DYSFPIYIEGLTQNGEVRFNIYSHSSVKNRRYEITTDVYENLPTDTKTIQDANLSKGTTE
CCCCEEEEEEECCCCEEEEEEEECCCCCCCEEEEEHHHHHCCCCCCCCCCCCCCCCCCHH
VVQKPYQGFKVKVYRNIYENEKFINKELISNDFYRPIQGIIKVGTKK
HHHCCCCCCEEEEEHHHHHCHHHHHHHHHCCCHHHHHHHHHHCCCCC
>Mature Secondary Structure
MLILGGEIMAKRKKRKKNSSKKITICLIIAAVLIGLTSVKAGYSYNNIKHYENLFYPGIT
CEEECCHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCEE
VGNEDISGKTLEEGRKIIKEKYANKLLNKKITVKIPEGEYSITFDKIEGKYDIDNSLKKA
ECCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEECCCCEEEEEECCCCCCCCCHHHHHH
YDYGKDSNAFSKYRIIKKAEKKPFELMFSYNEKKVIDFINDVEKKVNKDATNAKLIKKGE
HCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCCCHHEECCC
NFNIIPESVGKKLNKEKLQKDILTNINGDISKDLVVNGEVKNVQAKVTSDKLTSVNSLIA
CCCCCCHHHHHHCCHHHHHHHHHHCCCCCCCCCEEECCCCCCEEEEECHHHHHHHHHHHH
SFGTNYANISSQQRANNIRLSTESINGTVLMPGEVFSFNGAVGERTADRGYQAASVIIGN
HHCCCCCCCCHHHHCCCEEEEEECCCCEEEECCCEEEECCCCCCCCHHCCCCEEEEEECC
QVEDGLGGGICQTSSTLYNAALKANLKSVERAHHTLPSSYVPLGRDATVDWENIDYKFRN
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEECCCCCCEEECC
DYSFPIYIEGLTQNGEVRFNIYSHSSVKNRRYEITTDVYENLPTDTKTIQDANLSKGTTE
CCCCEEEEEEECCCCEEEEEEEECCCCCCCEEEEEHHHHHCCCCCCCCCCCCCCCCCCHH
VVQKPYQGFKVKVYRNIYENEKFINKELISNDFYRPIQGIIKVGTKK
HHHCCCCCCEEEEEHHHHHCHHHHHHHHHCCCHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]