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The map label for this gene is mreB [H]

Identifier: 28210078

GI number: 28210078

Start: 300216

End: 301247

Strand: Direct

Name: mreB [H]

Synonym: CTC00318

Alternate gene names: 28210078

Gene position: 300216-301247 (Clockwise)

Preceding gene: 28210077

Following gene: 28210081

Centisome position: 10.72

GC content: 34.88

Gene sequence:

>1032_bases
ATGTTTTTTAGCGTAGGAACAGATATGGGAATAGATCTTGGAACAGCCACTGTATTAGTTTATATCAAAGGAAAAGGTGT
AGTATTAAATGATCCATCAGTAGTAGCAATTGATAAGAGTAAACGCAAACTTTTAGCAGTAGGAGAAGAAGCAAGACAGA
TGATTGGCAGAACTCCTGGAAATATTGTGGCATTAAAACCTCTTAGAGGAGGAGTTATTTCTGATTACGATTTAACAGAA
AAAATGCTGAAATATTTTATTACTAAAGCTTGTGGAAAGAAGAAAATGGTTTCGCCAAGAGTAGTAGTATGTATACCTTG
TGAATCTACAGAAGTTGAGAAAAGAGCAGTTATAGATGCAGCAAGGAATGCTGGAGCTAAGAAAGTTTTTTTAATAGAAG
AACCCTTAGCAGCAGCAATAGGTGCAGGTGTTGATATAACTAAAGCCAGCGGTAATATGATAATTGATATAGGAGGAGGG
ACAACCGATATAGCGGTTATATCTTTAGGAGGAATAGTTGAAAGGTCTACAATAAGTATAGCGGGAGATAGCTTTGATGA
AGCTATAATAAAATACATACGAAAGAAACATAATCTTATGATAGGAGAAAGGACAGCAGAAGACTTAAAAATCAATGTAG
GATCTGTTTATGATAATGGCGAAGAACAATTTATGGATATAAGAGGAAGAGATTTAATATCAGGTTTACCAAAGAATATA
ACTGTATCATCATCAGAAATGAGAGAAGCCCTAATAGAACCTGTAAATACCATAGCAGAAAGTACTCATGCTATTTTAGA
AAAAACTCCACCAGAGTTAGCGGCAGATATATCTGATAAAGGTATAGTAATGACTGGCGGAGGGGCACTATTAAATGGTT
TAGATAAATTAATATCGGAGGTAACCCATGTTCCAGTATATGTTTCTGAGGAGGCGGTTACATGTGTAGCAATTGGAACG
GGTAAGATGTTAGAGTATTTAGATAAGTTAGATGTAACTTTCCTAGGAGACAATATAGTTTTAATAGATTAA

Upstream 100 bases:

>100_bases
CTATTGAAGGTTAAAAACATTCCTATTATAATTGATATTAGGTAATAGTATCAAATTTTACCAAAGAAGAATAAGGAAAG
AGTAGGTGTGAATAATAGGG

Downstream 100 bases:

>100_bases
ATATGAAACAAAGCAAAGAGTTTATGTCTTTGCTTTATTTTTATTTGGTAAAGTATATTTTTCACAAGTTAATTTGAATC
CATATATTATGGAATGAGAA

Product: rod shape-determining protein MreB

Products: NA

Alternate protein names: Protein mbl [H]

Number of amino acids: Translated: 343; Mature: 343

Protein sequence:

>343_residues
MFFSVGTDMGIDLGTATVLVYIKGKGVVLNDPSVVAIDKSKRKLLAVGEEARQMIGRTPGNIVALKPLRGGVISDYDLTE
KMLKYFITKACGKKKMVSPRVVVCIPCESTEVEKRAVIDAARNAGAKKVFLIEEPLAAAIGAGVDITKASGNMIIDIGGG
TTDIAVISLGGIVERSTISIAGDSFDEAIIKYIRKKHNLMIGERTAEDLKINVGSVYDNGEEQFMDIRGRDLISGLPKNI
TVSSSEMREALIEPVNTIAESTHAILEKTPPELAADISDKGIVMTGGGALLNGLDKLISEVTHVPVYVSEEAVTCVAIGT
GKMLEYLDKLDVTFLGDNIVLID

Sequences:

>Translated_343_residues
MFFSVGTDMGIDLGTATVLVYIKGKGVVLNDPSVVAIDKSKRKLLAVGEEARQMIGRTPGNIVALKPLRGGVISDYDLTE
KMLKYFITKACGKKKMVSPRVVVCIPCESTEVEKRAVIDAARNAGAKKVFLIEEPLAAAIGAGVDITKASGNMIIDIGGG
TTDIAVISLGGIVERSTISIAGDSFDEAIIKYIRKKHNLMIGERTAEDLKINVGSVYDNGEEQFMDIRGRDLISGLPKNI
TVSSSEMREALIEPVNTIAESTHAILEKTPPELAADISDKGIVMTGGGALLNGLDKLISEVTHVPVYVSEEAVTCVAIGT
GKMLEYLDKLDVTFLGDNIVLID
>Mature_343_residues
MFFSVGTDMGIDLGTATVLVYIKGKGVVLNDPSVVAIDKSKRKLLAVGEEARQMIGRTPGNIVALKPLRGGVISDYDLTE
KMLKYFITKACGKKKMVSPRVVVCIPCESTEVEKRAVIDAARNAGAKKVFLIEEPLAAAIGAGVDITKASGNMIIDIGGG
TTDIAVISLGGIVERSTISIAGDSFDEAIIKYIRKKHNLMIGERTAEDLKINVGSVYDNGEEQFMDIRGRDLISGLPKNI
TVSSSEMREALIEPVNTIAESTHAILEKTPPELAADISDKGIVMTGGGALLNGLDKLISEVTHVPVYVSEEAVTCVAIGT
GKMLEYLDKLDVTFLGDNIVLID

Specific function: Not essential for cell viability or sporulation [H]

COG id: COG1077

COG function: function code D; Actin-like ATPase involved in cell morphogenesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsA/mreB family [H]

Homologues:

Organism=Escherichia coli, GI87082236, Length=327, Percent_Identity=52.5993883792049, Blast_Score=357, Evalue=1e-100,
Organism=Saccharomyces cerevisiae, GI6322426, Length=258, Percent_Identity=26.7441860465116, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004753 [H]

Pfam domain/function: PF06723 MreB_Mbl [H]

EC number: NA

Molecular weight: Translated: 36568; Mature: 36568

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFFSVGTDMGIDLGTATVLVYIKGKGVVLNDPSVVAIDKSKRKLLAVGEEARQMIGRTPG
CEEECCCCCCCCCCCEEEEEEECCCEEEECCCCEEEEECCCCEEEEECHHHHHHHCCCCC
NIVALKPLRGGVISDYDLTEKMLKYFITKACGKKKMVSPRVVVCIPCESTEVEKRAVIDA
CEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCHHHHHHHH
ARNAGAKKVFLIEEPLAAAIGAGVDITKASGNMIIDIGGGTTDIAVISLGGIVERSTISI
HHCCCCEEEEEEECCHHHHHCCCCEEEECCCCEEEEECCCCCEEEEEEECCEEEEEEEEE
AGDSFDEAIIKYIRKKHNLMIGERTAEDLKINVGSVYDNGEEQFMDIRGRDLISGLPKNI
ECCCHHHHHHHHHHHHCCEEEECCCCCCEEEEECCEEECCHHHHHHCCCCHHHCCCCCCE
TVSSSEMREALIEPVNTIAESTHAILEKTPPELAADISDKGIVMTGGGALLNGLDKLISE
EECHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCEEEECCHHHHHHHHHHHHH
VTHVPVYVSEEAVTCVAIGTGKMLEYLDKLDVTFLGDNIVLID
HHHCCEEEECCCEEEEEECCCHHHHHHHHCCEEEECCEEEEEC
>Mature Secondary Structure
MFFSVGTDMGIDLGTATVLVYIKGKGVVLNDPSVVAIDKSKRKLLAVGEEARQMIGRTPG
CEEECCCCCCCCCCCEEEEEEECCCEEEECCCCEEEEECCCCEEEEECHHHHHHHCCCCC
NIVALKPLRGGVISDYDLTEKMLKYFITKACGKKKMVSPRVVVCIPCESTEVEKRAVIDA
CEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCHHHHHHHH
ARNAGAKKVFLIEEPLAAAIGAGVDITKASGNMIIDIGGGTTDIAVISLGGIVERSTISI
HHCCCCEEEEEEECCHHHHHCCCCEEEECCCCEEEEECCCCCEEEEEEECCEEEEEEEEE
AGDSFDEAIIKYIRKKHNLMIGERTAEDLKINVGSVYDNGEEQFMDIRGRDLISGLPKNI
ECCCHHHHHHHHHHHHCCEEEECCCCCCEEEEECCEEECCHHHHHHCCCCHHHCCCCCCE
TVSSSEMREALIEPVNTIAESTHAILEKTPPELAADISDKGIVMTGGGALLNGLDKLISE
EECHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCEEEECCHHHHHHHHHHHHH
VTHVPVYVSEEAVTCVAIGTGKMLEYLDKLDVTFLGDNIVLID
HHHCCEEEECCCEEEEEECCCHHHHHHHHCCEEEECCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7836311; 9384377; 10568751; 9353933 [H]