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The map label for this gene is coaE [H]

Identifier: 28199788

GI number: 28199788

Start: 2253607

End: 2254245

Strand: Reverse

Name: coaE [H]

Synonym: PD1921

Alternate gene names: 28199788

Gene position: 2254245-2253607 (Counterclockwise)

Preceding gene: 28199789

Following gene: 28199783

Centisome position: 89.46

GC content: 53.68

Gene sequence:

>639_bases
GTGAGGTTGGAGTTGATGAGTGTCTATGCGGTTGGTCTCACTGGAGGGGTCGCTTGCGGTAAGAGCTTGCTGGCGCAGCT
GTTCGAGGCGTTAAACACGACGGTTGTTGATGCAGATACAATTGCCCGCCAAGTGGTTGAGCCTGGTCCAGTTCTCAATT
GCATCGTTGCTAGGTTTGGTAGCAAGATTTTGCGGGCTGATGGTTGTCTTGATCGTCGTTTTTTGCGGCAACGTGTATTT
GCCGATGTGGCCGAACGAAAGGCGTTGGAGGCTATTGTCCATCCGGTGATCCGAGCTAGGTTGAAGCAGGCGGCGGCGGC
GGCGGCAGGTCCATATGTGCTAGTCGTCATTCCACTTTTGGCCGAGGCTGGTGGTCGCATTGGATACCCTTGGTTGCAGC
GCATTCTTGTCGTGGATGCTATACCGGAAGTACAACACGCACGACTGATGCAGCGTGATTCAATTGACGCTGAGCAGGCT
TCCTTGATGATCGCGGCCCAGATTGGCCGCAAAGAGCGCTTAGCTATAGCCGACGATATTGTGTTTAACGATGGAGATCC
CGCGCATTTGGGCGGGCAGGTATGCAATTTGGACGCGCGCTATCGCGCTCTTGCTTCTGTTTTTTCTGATGTTGATTAG

Upstream 100 bases:

>100_bases
CGATGATTCCGTTTGGACCTTATCTGGCAGTTGGTGGATGGATCGTGTTCTTTTTCGGCGATCAGATCATCCATGCTTAT
CTGGAGCTATTAAGTATCGG

Downstream 100 bases:

>100_bases
TATCAATTGTTGGCATTACCGAGAGACATCAATTCATCATTGTGACACTTAAATAGTGTACGGTGGTGGATGTTATTTGC
GGTTGTTATCTGCAAGAGTA

Product: dephospho-CoA kinase

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase [H]

Number of amino acids: Translated: 212; Mature: 212

Protein sequence:

>212_residues
MRLELMSVYAVGLTGGVACGKSLLAQLFEALNTTVVDADTIARQVVEPGPVLNCIVARFGSKILRADGCLDRRFLRQRVF
ADVAERKALEAIVHPVIRARLKQAAAAAAGPYVLVVIPLLAEAGGRIGYPWLQRILVVDAIPEVQHARLMQRDSIDAEQA
SLMIAAQIGRKERLAIADDIVFNDGDPAHLGGQVCNLDARYRALASVFSDVD

Sequences:

>Translated_212_residues
MRLELMSVYAVGLTGGVACGKSLLAQLFEALNTTVVDADTIARQVVEPGPVLNCIVARFGSKILRADGCLDRRFLRQRVF
ADVAERKALEAIVHPVIRARLKQAAAAAAGPYVLVVIPLLAEAGGRIGYPWLQRILVVDAIPEVQHARLMQRDSIDAEQA
SLMIAAQIGRKERLAIADDIVFNDGDPAHLGGQVCNLDARYRALASVFSDVD
>Mature_212_residues
MRLELMSVYAVGLTGGVACGKSLLAQLFEALNTTVVDADTIARQVVEPGPVLNCIVARFGSKILRADGCLDRRFLRQRVF
ADVAERKALEAIVHPVIRARLKQAAAAAAGPYVLVVIPLLAEAGGRIGYPWLQRILVVDAIPEVQHARLMQRDSIDAEQA
SLMIAAQIGRKERLAIADDIVFNDGDPAHLGGQVCNLDARYRALASVFSDVD

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A [H]

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain [H]

Homologues:

Organism=Homo sapiens, GI191252797, Length=183, Percent_Identity=34.9726775956284, Blast_Score=103, Evalue=1e-22,
Organism=Homo sapiens, GI191252795, Length=183, Percent_Identity=34.9726775956284, Blast_Score=103, Evalue=1e-22,
Organism=Homo sapiens, GI110227607, Length=167, Percent_Identity=32.3353293413174, Blast_Score=72, Evalue=3e-13,
Organism=Homo sapiens, GI110227605, Length=172, Percent_Identity=31.9767441860465, Blast_Score=71, Evalue=7e-13,
Organism=Homo sapiens, GI110227603, Length=172, Percent_Identity=31.9767441860465, Blast_Score=71, Evalue=7e-13,
Organism=Homo sapiens, GI110227601, Length=172, Percent_Identity=31.9767441860465, Blast_Score=71, Evalue=7e-13,
Organism=Homo sapiens, GI205277394, Length=179, Percent_Identity=32.4022346368715, Blast_Score=71, Evalue=9e-13,
Organism=Escherichia coli, GI1786292, Length=201, Percent_Identity=46.2686567164179, Blast_Score=171, Evalue=4e-44,
Organism=Caenorhabditis elegans, GI17554944, Length=196, Percent_Identity=33.6734693877551, Blast_Score=91, Evalue=4e-19,
Organism=Saccharomyces cerevisiae, GI6320402, Length=197, Percent_Identity=37.0558375634518, Blast_Score=88, Evalue=8e-19,
Organism=Drosophila melanogaster, GI24644728, Length=182, Percent_Identity=28.021978021978, Blast_Score=84, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24658602, Length=184, Percent_Identity=31.5217391304348, Blast_Score=71, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001977 [H]

Pfam domain/function: PF01121 CoaE [H]

EC number: =2.7.1.24 [H]

Molecular weight: Translated: 22896; Mature: 22896

Theoretical pI: Translated: 7.39; Mature: 7.39

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS01294 COAE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLELMSVYAVGLTGGVACGKSLLAQLFEALNTTVVDADTIARQVVEPGPVLNCIVARFG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCHHHHHHHHCCCCHHHHHHHHHHH
SKILRADGCLDRRFLRQRVFADVAERKALEAIVHPVIRARLKQAAAAAAGPYVLVVIPLL
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
AEAGGRIGYPWLQRILVVDAIPEVQHARLMQRDSIDAEQASLMIAAQIGRKERLAIADDI
HHCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHE
VFNDGDPAHLGGQVCNLDARYRALASVFSDVD
EECCCCCHHHCCCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRLELMSVYAVGLTGGVACGKSLLAQLFEALNTTVVDADTIARQVVEPGPVLNCIVARFG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCHHHHHHHHCCCCHHHHHHHHHHH
SKILRADGCLDRRFLRQRVFADVAERKALEAIVHPVIRARLKQAAAAAAGPYVLVVIPLL
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
AEAGGRIGYPWLQRILVVDAIPEVQHARLMQRDSIDAEQASLMIAAQIGRKERLAIADDI
HHCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHE
VFNDGDPAHLGGQVCNLDARYRALASVFSDVD
EECCCCCHHHCCCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]