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The map label for this gene is speD [H]

Identifier: 28198660

GI number: 28198660

Start: 927823

End: 928617

Strand: Reverse

Name: speD [H]

Synonym: PD0754

Alternate gene names: 28198660

Gene position: 928617-927823 (Counterclockwise)

Preceding gene: 28198662

Following gene: 28198658

Centisome position: 36.85

GC content: 45.66

Gene sequence:

>795_bases
ATGGTCAAGCCATTGCCTCGCCTGAGGTTACAAGGATTCAACAACCTCACCAAGGCGCTGAGCTTCAATATCTACGACGT
ATGCTACGCACGTACCGAAGAGGAGCGTCAGCGTTACATCGATTATATTGACGAGCGCTATGACGCTGATCGCCTGACTC
AGATCCTAACCGACGTGGCTGAGATCATCGGGGCTAACATCCTCAATATCGCCCGACAAGATTACGATCCCCAAGGAGCC
TCAGTCACCATTTTGATCTCCGAAGAGCCTGTAATCGATAAAAAGCAAGCAGGCAAAGAATTGATCTCCGATGCAGTGGT
TACGCACATGGATAAGAGTCACATCACGGTTCACACCTATCCTGAGACCCATCCACAGGAAGGGATCGCAACTTTCCGTG
CTGATATCGACGTGGCAACCTGCGGGGTCATATCGCCACTCAAAGCACTGAACTATTTGATCGAAAGCCTGGAGTCAGAC
ATCGTGATCATGGATTACCGTGTACGCGGCTTCACGCGTGACGTAAAGGGAAAAAAGCATTTCATTGACCATAAAATCAA
CTCGATCCAGAACTTTCTTTCCAAAAGCATCAAGTCACGCTACGAAATGTTCGATGTGAACGTGTACCAGGAAAATATCT
TTCACACAAAAATGCATTTGAAAGACTTTGATCTGGATCAGTATCTGTTTGAAGAAAAAGCAAGGAATCTTTCATTCAAG
GAACGCATGAAAATAGAAGCATTACTCAAACTTGAAATTGAGGAGTTATTTCACGGACGCAATTTGGCCGAATAA

Upstream 100 bases:

>100_bases
TGCCACGCGTAAACCATCACTAGCAATGGCATTTCGCTGCTGAGAACTTTGCCGCATAATTTCTTCTTCCCGCTTCTCTC
TTATTCCAGGATCAGCCGAC

Downstream 100 bases:

>100_bases
GCGTTTTGGAACTTCGTGACAAGCCCTGTGAACATGTCAGGGTTGTTTTTCTCCTTGTGAGTCATGCACAACGCCTTAGC
ACACTTCTACGTCAATATTA

Product: S-adenosylmethionine decarboxylase

Products: NA

Alternate protein names: AdoMetDC; SAMDC [H]

Number of amino acids: Translated: 264; Mature: 264

Protein sequence:

>264_residues
MVKPLPRLRLQGFNNLTKALSFNIYDVCYARTEEERQRYIDYIDERYDADRLTQILTDVAEIIGANILNIARQDYDPQGA
SVTILISEEPVIDKKQAGKELISDAVVTHMDKSHITVHTYPETHPQEGIATFRADIDVATCGVISPLKALNYLIESLESD
IVIMDYRVRGFTRDVKGKKHFIDHKINSIQNFLSKSIKSRYEMFDVNVYQENIFHTKMHLKDFDLDQYLFEEKARNLSFK
ERMKIEALLKLEIEELFHGRNLAE

Sequences:

>Translated_264_residues
MVKPLPRLRLQGFNNLTKALSFNIYDVCYARTEEERQRYIDYIDERYDADRLTQILTDVAEIIGANILNIARQDYDPQGA
SVTILISEEPVIDKKQAGKELISDAVVTHMDKSHITVHTYPETHPQEGIATFRADIDVATCGVISPLKALNYLIESLESD
IVIMDYRVRGFTRDVKGKKHFIDHKINSIQNFLSKSIKSRYEMFDVNVYQENIFHTKMHLKDFDLDQYLFEEKARNLSFK
ERMKIEALLKLEIEELFHGRNLAE
>Mature_264_residues
MVKPLPRLRLQGFNNLTKALSFNIYDVCYARTEEERQRYIDYIDERYDADRLTQILTDVAEIIGANILNIARQDYDPQGA
SVTILISEEPVIDKKQAGKELISDAVVTHMDKSHITVHTYPETHPQEGIATFRADIDVATCGVISPLKALNYLIESLESD
IVIMDYRVRGFTRDVKGKKHFIDHKINSIQNFLSKSIKSRYEMFDVNVYQENIFHTKMHLKDFDLDQYLFEEKARNLSFK
ERMKIEALLKLEIEELFHGRNLAE

Specific function: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine [H]

COG id: COG1586

COG function: function code E; S-adenosylmethionine decarboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786311, Length=262, Percent_Identity=66.030534351145, Blast_Score=361, Evalue=1e-101,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003826
- InterPro:   IPR009165
- InterPro:   IPR016067 [H]

Pfam domain/function: PF02675 AdoMet_dc [H]

EC number: =4.1.1.50 [H]

Molecular weight: Translated: 30735; Mature: 30735

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKPLPRLRLQGFNNLTKALSFNIYDVCYARTEEERQRYIDYIDERYDADRLTQILTDVA
CCCCCCHHHHCCCHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHH
EIIGANILNIARQDYDPQGASVTILISEEPVIDKKQAGKELISDAVVTHMDKSHITVHTY
HHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEC
PETHPQEGIATFRADIDVATCGVISPLKALNYLIESLESDIVIMDYRVRGFTRDVKGKKH
CCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCHHCCCCHHH
FIDHKINSIQNFLSKSIKSRYEMFDVNVYQENIFHTKMHLKDFDLDQYLFEEKARNLSFK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCHH
ERMKIEALLKLEIEELFHGRNLAE
HHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MVKPLPRLRLQGFNNLTKALSFNIYDVCYARTEEERQRYIDYIDERYDADRLTQILTDVA
CCCCCCHHHHCCCHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHH
EIIGANILNIARQDYDPQGASVTILISEEPVIDKKQAGKELISDAVVTHMDKSHITVHTY
HHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEC
PETHPQEGIATFRADIDVATCGVISPLKALNYLIESLESDIVIMDYRVRGFTRDVKGKKH
CCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCHHCCCCHHH
FIDHKINSIQNFLSKSIKSRYEMFDVNVYQENIFHTKMHLKDFDLDQYLFEEKARNLSFK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCHH
ERMKIEALLKLEIEELFHGRNLAE
HHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA