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The map label for this gene is cysJ [H]

Identifier: 62184834

GI number: 62184834

Start: 208468

End: 209517

Strand: Direct

Name: cysJ [H]

Synonym: CAB190

Alternate gene names: 62184834

Gene position: 208468-209517 (Clockwise)

Preceding gene: 161501895

Following gene: 62184836

Centisome position: 18.22

GC content: 39.52

Gene sequence:

>1050_bases
ATGCATTTGTTAGAGAAATTTAAAGCTCAGAGAGTGTCTCTTCTCTCAAGAGAGCTCATTTCTTGTTGCGATCCTGCTAT
TGCTTCTTCTGATGCAGGCCACGTTTATCAATTGCTCTTTAACACAACAGGCTCTAATCTGTCCTATAAGGTAGGGGATT
CTCTTGGTGTATTTCCAAAGAATCCCGTGCATGTTGTTGAGAAGATCCTTGAGTGTCTAAGTTATTCTCCAAAACAACTC
GTACAATCTCGAGAATCTTCTCAGATTTCCCTCTACGACTTCTTAAGATGTCATACCAATATCAATAAAGTTCCCCCAAA
GCTGAAGTCTTTTTTCCCCGACCTAGAAGAGACTATGACTTTCTACGATGCAATACAGAAATACCAACCCCATATCCCTG
TGGAATTGTTTGTAGAGAGTGTCTTGCCCTTATTGCCACGGTTTTATTCTATAGCTTCAGCTCCCCATCCTCATGAGAAT
CAGATAGAACTCTTAGTCAGGCTCGTGAATTATTCTGGAGAATATGAGCAACGCTACGGTGTCTGCTCTTTCTTTTTGTG
CAGGGAATTAGAATTAGGCAAAAGTTGTCATGTATTCGTACAACCAACCAAACACTTTACTCTTGCAGAGCATGTACAAA
ATCAACCTATTGTAATGATTGGTTCAGGAACAGGAATCGCTCCTTATAAAGCATTCGTGCAACAGCGTATCTACAATAAC
GATTCCGGTATGAACATACTCTTTTTTGGCGAACGTTTCGAAAAAGCAAATTTCTATTATCAAGATTTCTGGAAAAAAGC
CGTCGAAAATGAGTTGTTAAAGCTATTTTTAGCGTTTTCTCGCGACGGCGATCGTAAACTTTATGTGCAAGATCTACTCA
AACAACACGCAGACCTGGTTCTAAAAGCTTATCAAAAAGGCGCCTACTTCTTTGTATGCGGAAGTAAAGTACTAGGAAAT
GAGGTAAAAAAGACACTAGAAGATATTCTAGGAAAGAATAAGCTCTCCCAATTAAAGGAAGAGCACCGTTATGTCGCTGA
TGTGTATTAA

Upstream 100 bases:

>100_bases
TAGATCCTACAGGAAAAACTATAGATGCTTTAAAAATGTTAGCTCTTCCAGCAGGAGTTGATATTAAAATCAAAGCTGCA
TAAATTCATCTGACTCGGCT

Downstream 100 bases:

>100_bases
CCGCAGTACTCCATAATGGTAAGTATACAAAAACATTGCACACCATCACCACAACCAAAATCACTCAATCCCTCTCCTGA
AGTCGCAGTAATGCCTACAG

Product: putative oxidoreductase

Products: NA

Alternate protein names: SiR-FP [H]

Number of amino acids: Translated: 349; Mature: 349

Protein sequence:

>349_residues
MHLLEKFKAQRVSLLSRELISCCDPAIASSDAGHVYQLLFNTTGSNLSYKVGDSLGVFPKNPVHVVEKILECLSYSPKQL
VQSRESSQISLYDFLRCHTNINKVPPKLKSFFPDLEETMTFYDAIQKYQPHIPVELFVESVLPLLPRFYSIASAPHPHEN
QIELLVRLVNYSGEYEQRYGVCSFFLCRELELGKSCHVFVQPTKHFTLAEHVQNQPIVMIGSGTGIAPYKAFVQQRIYNN
DSGMNILFFGERFEKANFYYQDFWKKAVENELLKLFLAFSRDGDRKLYVQDLLKQHADLVLKAYQKGAYFFVCGSKVLGN
EVKKTLEDILGKNKLSQLKEEHRYVADVY

Sequences:

>Translated_349_residues
MHLLEKFKAQRVSLLSRELISCCDPAIASSDAGHVYQLLFNTTGSNLSYKVGDSLGVFPKNPVHVVEKILECLSYSPKQL
VQSRESSQISLYDFLRCHTNINKVPPKLKSFFPDLEETMTFYDAIQKYQPHIPVELFVESVLPLLPRFYSIASAPHPHEN
QIELLVRLVNYSGEYEQRYGVCSFFLCRELELGKSCHVFVQPTKHFTLAEHVQNQPIVMIGSGTGIAPYKAFVQQRIYNN
DSGMNILFFGERFEKANFYYQDFWKKAVENELLKLFLAFSRDGDRKLYVQDLLKQHADLVLKAYQKGAYFFVCGSKVLGN
EVKKTLEDILGKNKLSQLKEEHRYVADVY
>Mature_349_residues
MHLLEKFKAQRVSLLSRELISCCDPAIASSDAGHVYQLLFNTTGSNLSYKVGDSLGVFPKNPVHVVEKILECLSYSPKQL
VQSRESSQISLYDFLRCHTNINKVPPKLKSFFPDLEETMTFYDAIQKYQPHIPVELFVESVLPLLPRFYSIASAPHPHEN
QIELLVRLVNYSGEYEQRYGVCSFFLCRELELGKSCHVFVQPTKHFTLAEHVQNQPIVMIGSGTGIAPYKAFVQQRIYNN
DSGMNILFFGERFEKANFYYQDFWKKAVENELLKLFLAFSRDGDRKLYVQDLLKQHADLVLKAYQKGAYFFVCGSKVLGN
EVKKTLEDILGKNKLSQLKEEHRYVADVY

Specific function: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow f

COG id: COG0369

COG function: function code P; Sulfite reductase, alpha subunit (flavoprotein)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 flavodoxin-like domain [H]

Homologues:

Organism=Homo sapiens, GI7657393, Length=371, Percent_Identity=26.6846361185984, Blast_Score=122, Evalue=6e-28,
Organism=Homo sapiens, GI221316705, Length=380, Percent_Identity=26.0526315789474, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI221316709, Length=371, Percent_Identity=26.4150943396226, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI221316707, Length=323, Percent_Identity=27.5541795665635, Blast_Score=112, Evalue=6e-25,
Organism=Homo sapiens, GI10835173, Length=419, Percent_Identity=26.0143198090692, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI24041029, Length=370, Percent_Identity=28.9189189189189, Blast_Score=102, Evalue=7e-22,
Organism=Homo sapiens, GI40254422, Length=227, Percent_Identity=30.3964757709251, Blast_Score=92, Evalue=6e-19,
Organism=Homo sapiens, GI127139033, Length=238, Percent_Identity=27.3109243697479, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI169790958, Length=261, Percent_Identity=26.8199233716475, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI169790956, Length=261, Percent_Identity=26.8199233716475, Blast_Score=78, Evalue=1e-14,
Organism=Escherichia coli, GI1789123, Length=336, Percent_Identity=30.0595238095238, Blast_Score=151, Evalue=7e-38,
Organism=Caenorhabditis elegans, GI17554134, Length=368, Percent_Identity=26.9021739130435, Blast_Score=121, Evalue=5e-28,
Organism=Caenorhabditis elegans, GI17566446, Length=323, Percent_Identity=27.5541795665635, Blast_Score=94, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6321143, Length=372, Percent_Identity=26.6129032258064, Blast_Score=118, Evalue=1e-27,
Organism=Saccharomyces cerevisiae, GI6321832, Length=427, Percent_Identity=25.7611241217799, Blast_Score=99, Evalue=7e-22,
Organism=Saccharomyces cerevisiae, GI6325305, Length=283, Percent_Identity=26.5017667844523, Blast_Score=77, Evalue=3e-15,
Organism=Drosophila melanogaster, GI78706872, Length=390, Percent_Identity=27.6923076923077, Blast_Score=119, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24583543, Length=390, Percent_Identity=27.6923076923077, Blast_Score=119, Evalue=3e-27,
Organism=Drosophila melanogaster, GI78706876, Length=390, Percent_Identity=27.6923076923077, Blast_Score=119, Evalue=3e-27,
Organism=Drosophila melanogaster, GI24582192, Length=239, Percent_Identity=31.3807531380753, Blast_Score=105, Evalue=6e-23,
Organism=Drosophila melanogaster, GI17137192, Length=239, Percent_Identity=31.3807531380753, Blast_Score=104, Evalue=9e-23,
Organism=Drosophila melanogaster, GI24660907, Length=198, Percent_Identity=32.3232323232323, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24660903, Length=198, Percent_Identity=32.3232323232323, Blast_Score=84, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010199
- InterPro:   IPR003097
- InterPro:   IPR017927
- InterPro:   IPR001094
- InterPro:   IPR008254
- InterPro:   IPR001709
- InterPro:   IPR023173
- InterPro:   IPR001433
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00667 FAD_binding_1; PF00258 Flavodoxin_1; PF00175 NAD_binding_1 [H]

EC number: =1.8.1.2 [H]

Molecular weight: Translated: 40165; Mature: 40165

Theoretical pI: Translated: 8.01; Mature: 8.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHLLEKFKAQRVSLLSRELISCCDPAIASSDAGHVYQLLFNTTGSNLSYKVGDSLGVFPK
CCHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCHHHHHHHHCCCCCCEEECCCCCCCCCC
NPVHVVEKILECLSYSPKQLVQSRESSQISLYDFLRCHTNINKVPPKLKSFFPDLEETMT
CHHHHHHHHHHHHCCCHHHHHHCCCCCCCHHHHHHHHHCCCCCCCHHHHHHCCCHHHHHH
FYDAIQKYQPHIPVELFVESVLPLLPRFYSIASAPHPHENQIELLVRLVNYSGEYEQRYG
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCHHHHHH
VCSFFLCRELELGKSCHVFVQPTKHFTLAEHVQNQPIVMIGSGTGIAPYKAFVQQRIYNN
HHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHCC
DSGMNILFFGERFEKANFYYQDFWKKAVENELLKLFLAFSRDGDRKLYVQDLLKQHADLV
CCCCEEEEECCHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
LKAYQKGAYFFVCGSKVLGNEVKKTLEDILGKNKLSQLKEEHRYVADVY
HHHHHCCCEEEEECCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MHLLEKFKAQRVSLLSRELISCCDPAIASSDAGHVYQLLFNTTGSNLSYKVGDSLGVFPK
CCHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCHHHHHHHHCCCCCCEEECCCCCCCCCC
NPVHVVEKILECLSYSPKQLVQSRESSQISLYDFLRCHTNINKVPPKLKSFFPDLEETMT
CHHHHHHHHHHHHCCCHHHHHHCCCCCCCHHHHHHHHHCCCCCCCHHHHHHCCCHHHHHH
FYDAIQKYQPHIPVELFVESVLPLLPRFYSIASAPHPHENQIELLVRLVNYSGEYEQRYG
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCHHHHHH
VCSFFLCRELELGKSCHVFVQPTKHFTLAEHVQNQPIVMIGSGTGIAPYKAFVQQRIYNN
HHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHCC
DSGMNILFFGERFEKANFYYQDFWKKAVENELLKLFLAFSRDGDRKLYVQDLLKQHADLV
CCCCEEEEECCHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
LKAYQKGAYFFVCGSKVLGNEVKKTLEDILGKNKLSQLKEEHRYVADVY
HHHHHCCCEEEEECCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA