Click here to switch to the map view.

The map label for this gene is coaE [H]

Identifier: 62184773

GI number: 62184773

Start: 136827

End: 137444

Strand: Direct

Name: coaE [H]

Synonym: CAB128

Alternate gene names: 62184773

Gene position: 136827-137444 (Clockwise)

Preceding gene: 62184772

Following gene: 62184774

Centisome position: 11.96

GC content: 37.22

Gene sequence:

>618_bases
TTGGGCAGAATGTTAGAATTGCTAAAAGTTTCTATTACAGGGGATCTCTCTTCGGGAAAGACTGAGGCGTGTAGGGTTTT
TCAAGAGCTGGGAGCCTATGTAATTAGTGCTGATAAAGTTTCGCATAGTTTCCTTGTTCCTCACTCGCACATAGGTCGTC
GCGTTATAGATCTCCTGGGACCAGAAGTTGTTATTGACAATACATTTGATAGAAAAGTCATAGCAGAAAAAGTTTTTGGT
AATTTAGATCTGCTGCAAGCTTTAGAAGCTATTTTGCATCCTGAAGTTTGTCGAATTATTGAAGAGCAGTATTGTCAAGT
CGCTAAAGAGCGAAAGTACCCTCTGTTCATTGCTGAGGTGCCTTTGTTGTACGAAATACATTATGCGAGATGGTTTGATC
GTGTAATTCTAATTACAGCTGATGAGAATATTCGTAGGGAAAGGTTTACCAAAAAAACTAATTGTTCTGATTTAAATTTT
TATCAGAGATGTGCACGGTTTTCTTCTCATGAGGAAAAAATGATGCATGCCGATATTGTTATCGAAAATAACGGTACTAA
AGAAGAATTACGTCATAAAGTTGAAGAATATTTTTACGCTTTAAAGGGAGCACTATGA

Upstream 100 bases:

>100_bases
AGGAAGAAAAAGAAGAAGTGCAAACTTTAGTGCGAGATATAATGGAATCTGCAATGATTTTATCTGTCCCATTAGTTGTG
AATATCTTAATTGGAAAAAA

Downstream 100 bases:

>100_bases
AAGAAGAACGTTCTTCAGAAGTCTTGCCAAAGGTCAAAGAGAATAGAAAACATGCGTGTCCTGGGTTGCAAGAGAAGTCT
TTTGCGGGAGAATGTGCAGT

Product: dephospho-CoA kinase

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase [H]

Number of amino acids: Translated: 205; Mature: 204

Protein sequence:

>205_residues
MGRMLELLKVSITGDLSSGKTEACRVFQELGAYVISADKVSHSFLVPHSHIGRRVIDLLGPEVVIDNTFDRKVIAEKVFG
NLDLLQALEAILHPEVCRIIEEQYCQVAKERKYPLFIAEVPLLYEIHYARWFDRVILITADENIRRERFTKKTNCSDLNF
YQRCARFSSHEEKMMHADIVIENNGTKEELRHKVEEYFYALKGAL

Sequences:

>Translated_205_residues
MGRMLELLKVSITGDLSSGKTEACRVFQELGAYVISADKVSHSFLVPHSHIGRRVIDLLGPEVVIDNTFDRKVIAEKVFG
NLDLLQALEAILHPEVCRIIEEQYCQVAKERKYPLFIAEVPLLYEIHYARWFDRVILITADENIRRERFTKKTNCSDLNF
YQRCARFSSHEEKMMHADIVIENNGTKEELRHKVEEYFYALKGAL
>Mature_204_residues
GRMLELLKVSITGDLSSGKTEACRVFQELGAYVISADKVSHSFLVPHSHIGRRVIDLLGPEVVIDNTFDRKVIAEKVFGN
LDLLQALEAILHPEVCRIIEEQYCQVAKERKYPLFIAEVPLLYEIHYARWFDRVILITADENIRRERFTKKTNCSDLNFY
QRCARFSSHEEKMMHADIVIENNGTKEELRHKVEEYFYALKGAL

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A [H]

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain [H]

Homologues:

Organism=Homo sapiens, GI191252797, Length=179, Percent_Identity=26.8156424581006, Blast_Score=78, Evalue=6e-15,
Organism=Homo sapiens, GI191252795, Length=179, Percent_Identity=26.8156424581006, Blast_Score=78, Evalue=6e-15,
Organism=Escherichia coli, GI1786292, Length=186, Percent_Identity=25.8064516129032, Blast_Score=74, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17554944, Length=195, Percent_Identity=30.2564102564103, Blast_Score=87, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24644728, Length=182, Percent_Identity=26.9230769230769, Blast_Score=77, Evalue=9e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001977 [H]

Pfam domain/function: PF01121 CoaE [H]

EC number: =2.7.1.24 [H]

Molecular weight: Translated: 23776; Mature: 23645

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: PS01294 COAE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGRMLELLKVSITGDLSSGKTEACRVFQELGAYVISADKVSHSFLVPHSHIGRRVIDLLG
CCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHEEEHHHCCCEEECCHHHHHHHHHHHHC
PEVVIDNTFDRKVIAEKVFGNLDLLQALEAILHPEVCRIIEEQYCQVAKERKYPLFIAEV
CCEEEECCCHHHHHHHHHHCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCEEEECC
PLLYEIHYARWFDRVILITADENIRRERFTKKTNCSDLNFYQRCARFSSHEEKMMHADIV
CHHHHHHHHHHHCEEEEEECCCHHHHHHHHCCCCCCCCHHHHHHHHHCCHHHHHHHEEEE
IENNGTKEELRHKVEEYFYALKGAL
EECCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
GRMLELLKVSITGDLSSGKTEACRVFQELGAYVISADKVSHSFLVPHSHIGRRVIDLLG
CHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHEEEHHHCCCEEECCHHHHHHHHHHHHC
PEVVIDNTFDRKVIAEKVFGNLDLLQALEAILHPEVCRIIEEQYCQVAKERKYPLFIAEV
CCEEEECCCHHHHHHHHHHCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCEEEECC
PLLYEIHYARWFDRVILITADENIRRERFTKKTNCSDLNFYQRCARFSSHEEKMMHADIV
CHHHHHHHHHHHCEEEEEECCCHHHHHHHHCCCCCCCCHHHHHHHHHCCHHHHHHHEEEE
IENNGTKEELRHKVEEYFYALKGAL
EECCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA