| Definition | Chlamydophila abortus S26/3, complete genome. |
|---|---|
| Accession | NC_004552 |
| Length | 1,144,377 |
Click here to switch to the map view.
The map label for this gene is polA [H]
Identifier: 62184772
GI number: 62184772
Start: 134233
End: 136842
Strand: Direct
Name: polA [H]
Synonym: CAB127
Alternate gene names: 62184772
Gene position: 134233-136842 (Clockwise)
Preceding gene: 62184771
Following gene: 62184773
Centisome position: 11.73
GC content: 39.0
Gene sequence:
>2610_bases GTGAGAAAGGTCTTTATTTTAGATGCTTCAGGATTTGTTTTTAGAGCATATTTTGCTCTCCCTGATATGAAAAATTCTTC AGGAGAAGGAACTCAAGCCGTGTTTGGCTTTATTCGTTCTATGAATAAATTAATAAAAGAATTCTCTCCTAAGCATATGG TTGCTGTGTTTGATGGTCCAAACAACAAACAGAGTCGTAGAGAAATTTATGCGGATTATAAAATTCATCGGGAGAAACAA GATGAGAATCTCTACCAACAAATTCCTATAGTTAAAGAATATTGTCATTTACTCGGGTTACGTTATTTAGAAATAGAAGG CGTTGAAGCTGACGATGTTATAGCGAGTATCACAAAGCAGGCAGTTTCAGAAGGATGTGAAGTTTGCCTATGTACCGCAG ATAAAGATCTACTCCAACTTGTAGGCCCGAATGTTGTGGCCTGGAATCCTTGGAAAGCTGGACCTCCTATCGATGAAAAT AGTGTTGTAGATATCTATGGTGTCCCCCCGAGCAGAATAGCCGATTATCTGGCTTTGGTGGGGGATACCTCAGATAATAT TCCAGGAGTCTCTGGTTGTGGACCTCAAAAAGCTACAGCTCTGTTACAAAAATATCATTCTGTTGAAGGTATTCTGGAAC ATCTTGATGAATTGACAGGTTCCACTCATAAAATGATCTCCGAACAAAAAGATGTATTGTTATTAAGTAAGGACCTCGCT GTATTAGATAACAATGTACCTCTTCCTATGGGCATAAGTGGATTTGCCTTTCCTCTACACGAGGTGCCCCAGGAAGAAAT CAATACCTTCTACATGCGTCATGGTTTTAAAACCTTGGTCCAACCAGTCGAAGAAGCGTCAAACATCGATATAGAGATCA TTCATAGTTGTCAGCCCTTAGTTCGTGTCTTGTCTACTTTACAGGGAAAGAGTGTCGCTTTTTCTGTAGGGTACAAGGGG AACTTTCTTCCCTCTCTTACGTTAATGGGAGTCGCTTTAGCCTGCGATGAACAAGTGTATTACGTTGATATAGAACATGC CCAAGACGATGTCATCACGCCATTACGCGATTTCTTCAAAAGAAAAGATACTGAATTTTACGGTTATAATATCAAGAGGG ATAACCATGCGTTAAAAAATGCTGGCATTCACATTCATAATATAACCCTGGATTTAGCCTTAGCAGAACATTTGATCAAC GGTGGAGCGAAGATTTCTTACCAAACACTTCTCGTTGATCATGGGTTAGTAGAGTCTGCAGGTAAGTATGGAAAGGAATG GGGACAATTAAGTCTCCCTATATTGAAATCCCCCGCCAAACCTGCGGAATATTTCGGAGAATTTGTTTCTCATCTGCCTA AAATCAAAAAATCACTGTTAGAAGAATTAAAAGTCAAAGGACTAGAAGATCTATTTTTCAACATGGAAATGCCCCTAGAG AAAGTCCTATTCACGATTGAAAGAAATGGGATGCCACTAGATGTGGAGGATCTTCAAGAGCTTGAGAGAACTTTATCAGA GGAATTAGCAATTCTTACTGATGATATTTATACAGTAGCTGGGACGTCTTTTAATATTAAATCTCCTAAGCAGTTGTCAG ATGTTTTATATAATAAATTAGGCCTAACACCTATAGATAAAGCTCGATCAACGAAGGCAGAAGTTTTGGCAGCCTTATTA GGAGAGCACGAAATAGTTGAAAAAATTTTAGCATTTAGAGCTATTGAGAAGTTACTCTCTACCTATGTTAAAGCTTTGCC TAGGCAAATAGATCCTCATACTTCTAGGATACACCCGACATTTAATCAGATGGGGACAGTCACAGGTAGGTTGGCTTGTC AGGATCCAAATTTACAGAATATTCCTATACGCTCTGAGCGAGGAAGATTGTTAAGAAAAGCGTTCTGTGATACGCGTCAG AATAATTATTTTTTATCTGCAGATTATTCTCAAATTGAGTTAAGATTCCTGGCGCATTTGAGTCAAGATGAGTCGTTGAG GTTGGCGTTCGCGTCGCGAGAAGATGTCCACACATTTACAGCTTCTCAGGTATTTCATGTGCCTTTAGAAGAAGTCACCA AGCAACAGCGCATGCAAGCAAAAACTGTAAATTTTGGTATTATCTATGGGCAACAAGCTTATGGACTCTCTAAGATTTTA AAAATCAGTGTTTCTGAAGCTCAGAAGTTAATAGATGCATATTTTGATCGTTATCCTGCAGTAGCTCGTTTTATTAATGA AACGATAAACGAAGCTTGTGAAAATTTGCGTGTAAAGACGTTACTGGGACGAGAAAGAATCATTGACAATTGGACAGAGT TTTCGAACTCTCGTGCTGCTTCAGGTCGTCTTGCCGTTAATACCCGCATTCAAGGTAGCGCAGCTGAATTGATCAAGTTA GCGATGCTACAGCTTGCTGCTGCGTTGGAAAAACGCAAATTAAGAAGCCGTATGCTGTTACAAATACATGATGAATTGAT CTTTGAAGTCCCTGAGGAAGAAAAAGAAGAAGTGCAAACTTTAGTGCGAGATATAATGGAATCTGCAATGATTTTATCTG TCCCATTAGTTGTGAATATCTTAATTGGAAAAAATTGGGCAGAATGTTAG
Upstream 100 bases:
>100_bases AGGAAAGATTCAACATGAGTTGCTCCCAAGCTTAGATAATTCCATAAGTACATTTTACTACTTAGATTCGTGATTCTGAT TCATAGGGCGGAGAGAATTA
Downstream 100 bases:
>100_bases AATTGCTAAAAGTTTCTATTACAGGGGATCTCTCTTCGGGAAAGACTGAGGCGTGTAGGGTTTTTCAAGAGCTGGGAGCC TATGTAATTAGTGCTGATAA
Product: DNA polymerase I
Products: NA
Alternate protein names: POL I [H]
Number of amino acids: Translated: 869; Mature: 869
Protein sequence:
>869_residues MRKVFILDASGFVFRAYFALPDMKNSSGEGTQAVFGFIRSMNKLIKEFSPKHMVAVFDGPNNKQSRREIYADYKIHREKQ DENLYQQIPIVKEYCHLLGLRYLEIEGVEADDVIASITKQAVSEGCEVCLCTADKDLLQLVGPNVVAWNPWKAGPPIDEN SVVDIYGVPPSRIADYLALVGDTSDNIPGVSGCGPQKATALLQKYHSVEGILEHLDELTGSTHKMISEQKDVLLLSKDLA VLDNNVPLPMGISGFAFPLHEVPQEEINTFYMRHGFKTLVQPVEEASNIDIEIIHSCQPLVRVLSTLQGKSVAFSVGYKG NFLPSLTLMGVALACDEQVYYVDIEHAQDDVITPLRDFFKRKDTEFYGYNIKRDNHALKNAGIHIHNITLDLALAEHLIN GGAKISYQTLLVDHGLVESAGKYGKEWGQLSLPILKSPAKPAEYFGEFVSHLPKIKKSLLEELKVKGLEDLFFNMEMPLE KVLFTIERNGMPLDVEDLQELERTLSEELAILTDDIYTVAGTSFNIKSPKQLSDVLYNKLGLTPIDKARSTKAEVLAALL GEHEIVEKILAFRAIEKLLSTYVKALPRQIDPHTSRIHPTFNQMGTVTGRLACQDPNLQNIPIRSERGRLLRKAFCDTRQ NNYFLSADYSQIELRFLAHLSQDESLRLAFASREDVHTFTASQVFHVPLEEVTKQQRMQAKTVNFGIIYGQQAYGLSKIL KISVSEAQKLIDAYFDRYPAVARFINETINEACENLRVKTLLGRERIIDNWTEFSNSRAASGRLAVNTRIQGSAAELIKL AMLQLAAALEKRKLRSRMLLQIHDELIFEVPEEEKEEVQTLVRDIMESAMILSVPLVVNILIGKNWAEC
Sequences:
>Translated_869_residues MRKVFILDASGFVFRAYFALPDMKNSSGEGTQAVFGFIRSMNKLIKEFSPKHMVAVFDGPNNKQSRREIYADYKIHREKQ DENLYQQIPIVKEYCHLLGLRYLEIEGVEADDVIASITKQAVSEGCEVCLCTADKDLLQLVGPNVVAWNPWKAGPPIDEN SVVDIYGVPPSRIADYLALVGDTSDNIPGVSGCGPQKATALLQKYHSVEGILEHLDELTGSTHKMISEQKDVLLLSKDLA VLDNNVPLPMGISGFAFPLHEVPQEEINTFYMRHGFKTLVQPVEEASNIDIEIIHSCQPLVRVLSTLQGKSVAFSVGYKG NFLPSLTLMGVALACDEQVYYVDIEHAQDDVITPLRDFFKRKDTEFYGYNIKRDNHALKNAGIHIHNITLDLALAEHLIN GGAKISYQTLLVDHGLVESAGKYGKEWGQLSLPILKSPAKPAEYFGEFVSHLPKIKKSLLEELKVKGLEDLFFNMEMPLE KVLFTIERNGMPLDVEDLQELERTLSEELAILTDDIYTVAGTSFNIKSPKQLSDVLYNKLGLTPIDKARSTKAEVLAALL GEHEIVEKILAFRAIEKLLSTYVKALPRQIDPHTSRIHPTFNQMGTVTGRLACQDPNLQNIPIRSERGRLLRKAFCDTRQ NNYFLSADYSQIELRFLAHLSQDESLRLAFASREDVHTFTASQVFHVPLEEVTKQQRMQAKTVNFGIIYGQQAYGLSKIL KISVSEAQKLIDAYFDRYPAVARFINETINEACENLRVKTLLGRERIIDNWTEFSNSRAASGRLAVNTRIQGSAAELIKL AMLQLAAALEKRKLRSRMLLQIHDELIFEVPEEEKEEVQTLVRDIMESAMILSVPLVVNILIGKNWAEC >Mature_869_residues MRKVFILDASGFVFRAYFALPDMKNSSGEGTQAVFGFIRSMNKLIKEFSPKHMVAVFDGPNNKQSRREIYADYKIHREKQ DENLYQQIPIVKEYCHLLGLRYLEIEGVEADDVIASITKQAVSEGCEVCLCTADKDLLQLVGPNVVAWNPWKAGPPIDEN SVVDIYGVPPSRIADYLALVGDTSDNIPGVSGCGPQKATALLQKYHSVEGILEHLDELTGSTHKMISEQKDVLLLSKDLA VLDNNVPLPMGISGFAFPLHEVPQEEINTFYMRHGFKTLVQPVEEASNIDIEIIHSCQPLVRVLSTLQGKSVAFSVGYKG NFLPSLTLMGVALACDEQVYYVDIEHAQDDVITPLRDFFKRKDTEFYGYNIKRDNHALKNAGIHIHNITLDLALAEHLIN GGAKISYQTLLVDHGLVESAGKYGKEWGQLSLPILKSPAKPAEYFGEFVSHLPKIKKSLLEELKVKGLEDLFFNMEMPLE KVLFTIERNGMPLDVEDLQELERTLSEELAILTDDIYTVAGTSFNIKSPKQLSDVLYNKLGLTPIDKARSTKAEVLAALL GEHEIVEKILAFRAIEKLLSTYVKALPRQIDPHTSRIHPTFNQMGTVTGRLACQDPNLQNIPIRSERGRLLRKAFCDTRQ NNYFLSADYSQIELRFLAHLSQDESLRLAFASREDVHTFTASQVFHVPLEEVTKQQRMQAKTVNFGIIYGQQAYGLSKIL KISVSEAQKLIDAYFDRYPAVARFINETINEACENLRVKTLLGRERIIDNWTEFSNSRAASGRLAVNTRIQGSAAELIKL AMLQLAAALEKRKLRSRMLLQIHDELIFEVPEEEKEEVQTLVRDIMESAMILSVPLVVNILIGKNWAEC
Specific function: In addition to polymerase activity, this DNA polymerase exhibits 3' to 5' and 5' to 3' exonuclease activity [H]
COG id: COG0749
COG function: function code L; DNA polymerase I - 3'-5' exonuclease and polymerase domains
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 5'-3' exonuclease domain [H]
Homologues:
Organism=Homo sapiens, GI112420958, Length=517, Percent_Identity=31.9148936170213, Blast_Score=213, Evalue=7e-55, Organism=Homo sapiens, GI139394648, Length=523, Percent_Identity=28.6806883365201, Blast_Score=178, Evalue=3e-44, Organism=Escherichia coli, GI1790294, Length=934, Percent_Identity=34.3683083511777, Blast_Score=480, Evalue=1e-136, Organism=Escherichia coli, GI226510970, Length=223, Percent_Identity=30.4932735426009, Blast_Score=114, Evalue=3e-26, Organism=Caenorhabditis elegans, GI86563272, Length=426, Percent_Identity=30.7511737089202, Blast_Score=184, Evalue=2e-46, Organism=Drosophila melanogaster, GI17933644, Length=581, Percent_Identity=27.5387263339071, Blast_Score=178, Evalue=1e-44,
Paralogues:
None
Copy number: 400 Molecules/Cell In: Glucose minimal media [C]
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002562 - InterPro: IPR020046 - InterPro: IPR020045 - InterPro: IPR002421 - InterPro: IPR020047 - InterPro: IPR019760 - InterPro: IPR001098 - InterPro: IPR018320 - InterPro: IPR002298 - InterPro: IPR008918 - InterPro: IPR003583 - InterPro: IPR012337 [H]
Pfam domain/function: PF01367 5_3_exonuc; PF02739 5_3_exonuc_N; PF00476 DNA_pol_A [H]
EC number: =2.7.7.7 [H]
Molecular weight: Translated: 97735; Mature: 97735
Theoretical pI: Translated: 5.97; Mature: 5.97
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.3 %Cys (Translated Protein) 2.0 %Met (Translated Protein) 3.2 %Cys+Met (Translated Protein) 1.3 %Cys (Mature Protein) 2.0 %Met (Mature Protein) 3.2 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MRKVFILDASGFVFRAYFALPDMKNSSGEGTQAVFGFIRSMNKLIKEFSPKHMVAVFDGP CCEEEEEECCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECC NNKQSRREIYADYKIHREKQDENLYQQIPIVKEYCHLLGLRYLEIEGVEADDVIASITKQ CCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHH AVSEGCEVCLCTADKDLLQLVGPNVVAWNPWKAGPPIDENSVVDIYGVPPSRIADYLALV HHHCCCCEEEEECCHHHHHHHCCCEEEECCCCCCCCCCCCCEEEEECCCHHHHHHHHHHH GDTSDNIPGVSGCGPQKATALLQKYHSVEGILEHLDELTGSTHKMISEQKDVLLLSKDLA CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCEEEEECCHH VLDNNVPLPMGISGFAFPLHEVPQEEINTFYMRHGFKTLVQPVEEASNIDIEIIHSCQPL HHCCCCCCCCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHH VRVLSTLQGKSVAFSVGYKGNFLPSLTLMGVALACDEQVYYVDIEHAQDDVITPLRDFFK HHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHEECCEEEEEEECCCCCHHHHHHHHHHH RKDTEFYGYNIKRDNHALKNAGIHIHNITLDLALAEHLINGGAKISYQTLLVDHGLVESA HCCCCEECEEECCCCCHHHHCCEEEEEEEHHHHHHHHHHCCCCEEEEEEEEHHCHHHHHH GKYGKEWGQLSLPILKSPAKPAEYFGEFVSHLPKIKKSLLEELKVKGLEDLFFNMEMPLE HHHHHHCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCHH KVLFTIERNGMPLDVEDLQELERTLSEELAILTDDIYTVAGTSFNIKSPKQLSDVLYNKL HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHEEECCCCCCCCHHHHHHHHHHHC GLTPIDKARSTKAEVLAALLGEHEIVEKILAFRAIEKLLSTYVKALPRQIDPHTSRIHPT CCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC FNQMGTVTGRLACQDPNLQNIPIRSERGRLLRKAFCDTRQNNYFLSADYSQIELRFLAHL HHHHCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHC SQDESLRLAFASREDVHTFTASQVFHVPLEEVTKQQRMQAKTVNFGIIYGQQAYGLSKIL CCCCCEEEEECCCCCHHHHHHHHEEECCHHHHHHHHHHHHHHEEEEEEECCHHHCHHHHH KISVSEAQKLIDAYFDRYPAVARFINETINEACENLRVKTLLGRERIIDNWTEFSNSRAA HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCC SGRLAVNTRIQGSAAELIKLAMLQLAAALEKRKLRSRMLLQIHDELIFEVPEEEKEEVQT CCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH LVRDIMESAMILSVPLVVNILIGKNWAEC HHHHHHHHHHHHHHHHHHHHHHCCCCCCC >Mature Secondary Structure MRKVFILDASGFVFRAYFALPDMKNSSGEGTQAVFGFIRSMNKLIKEFSPKHMVAVFDGP CCEEEEEECCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECC NNKQSRREIYADYKIHREKQDENLYQQIPIVKEYCHLLGLRYLEIEGVEADDVIASITKQ CCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHH AVSEGCEVCLCTADKDLLQLVGPNVVAWNPWKAGPPIDENSVVDIYGVPPSRIADYLALV HHHCCCCEEEEECCHHHHHHHCCCEEEECCCCCCCCCCCCCEEEEECCCHHHHHHHHHHH GDTSDNIPGVSGCGPQKATALLQKYHSVEGILEHLDELTGSTHKMISEQKDVLLLSKDLA CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCEEEEECCHH VLDNNVPLPMGISGFAFPLHEVPQEEINTFYMRHGFKTLVQPVEEASNIDIEIIHSCQPL HHCCCCCCCCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHH VRVLSTLQGKSVAFSVGYKGNFLPSLTLMGVALACDEQVYYVDIEHAQDDVITPLRDFFK HHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHEECCEEEEEEECCCCCHHHHHHHHHHH RKDTEFYGYNIKRDNHALKNAGIHIHNITLDLALAEHLINGGAKISYQTLLVDHGLVESA HCCCCEECEEECCCCCHHHHCCEEEEEEEHHHHHHHHHHCCCCEEEEEEEEHHCHHHHHH GKYGKEWGQLSLPILKSPAKPAEYFGEFVSHLPKIKKSLLEELKVKGLEDLFFNMEMPLE HHHHHHCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCHH KVLFTIERNGMPLDVEDLQELERTLSEELAILTDDIYTVAGTSFNIKSPKQLSDVLYNKL HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHEEECCCCCCCCHHHHHHHHHHHC GLTPIDKARSTKAEVLAALLGEHEIVEKILAFRAIEKLLSTYVKALPRQIDPHTSRIHPT CCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC FNQMGTVTGRLACQDPNLQNIPIRSERGRLLRKAFCDTRQNNYFLSADYSQIELRFLAHL HHHHCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHC SQDESLRLAFASREDVHTFTASQVFHVPLEEVTKQQRMQAKTVNFGIIYGQQAYGLSKIL CCCCCEEEEECCCCCHHHHHHHHEEECCHHHHHHHHHHHHHHEEEEEEECCHHHCHHHHH KISVSEAQKLIDAYFDRYPAVARFINETINEACENLRVKTLLGRERIIDNWTEFSNSRAA HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCC SGRLAVNTRIQGSAAELIKLAMLQLAAALEKRKLRSRMLLQIHDELIFEVPEEEKEEVQT CCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH LVRDIMESAMILSVPLVVNILIGKNWAEC HHHHHHHHHHHHHHHHHHHHHHCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 9387221; 9384377 [H]